DK0915087T3 - Sulfonamid-substituerede anellerede 5-leddede ringforbindelser, deres anvendelse som lægemiddel samt farmaceutiske præparater, som indeholder dem - Google Patents

Sulfonamid-substituerede anellerede 5-leddede ringforbindelser, deres anvendelse som lægemiddel samt farmaceutiske præparater, som indeholder dem

Info

Publication number
DK0915087T3
DK0915087T3 DK98120913T DK98120913T DK0915087T3 DK 0915087 T3 DK0915087 T3 DK 0915087T3 DK 98120913 T DK98120913 T DK 98120913T DK 98120913 T DK98120913 T DK 98120913T DK 0915087 T3 DK0915087 T3 DK 0915087T3
Authority
DK
Denmark
Prior art keywords
sulfonamide
annealed
drug
substituted
pharmaceutical compositions
Prior art date
Application number
DK98120913T
Other languages
English (en)
Inventor
Joachim Dr Brendel
Uwe Dr Gerlach
Hans Jochen Dr Lang
Klaus Dr Weidmann
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of DK0915087T3 publication Critical patent/DK0915087T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/07—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK98120913T 1997-11-10 1998-11-04 Sulfonamid-substituerede anellerede 5-leddede ringforbindelser, deres anvendelse som lægemiddel samt farmaceutiske præparater, som indeholder dem DK0915087T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19749453A DE19749453A1 (de) 1997-11-10 1997-11-10 Sulfonamid-substituierte anellierte 5-Ring-Verbindungen, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
DK0915087T3 true DK0915087T3 (da) 2003-07-21

Family

ID=7848065

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98120913T DK0915087T3 (da) 1997-11-10 1998-11-04 Sulfonamid-substituerede anellerede 5-leddede ringforbindelser, deres anvendelse som lægemiddel samt farmaceutiske præparater, som indeholder dem

Country Status (29)

Country Link
US (1) US6015822A (da)
EP (1) EP0915087B1 (da)
JP (1) JP4331809B2 (da)
KR (1) KR19990045147A (da)
CN (1) CN1219533A (da)
AR (1) AR016006A1 (da)
AT (1) ATE236120T1 (da)
AU (1) AU742199B2 (da)
BR (1) BR9804995A (da)
CA (1) CA2253211C (da)
CZ (1) CZ363798A3 (da)
DE (2) DE19749453A1 (da)
DK (1) DK0915087T3 (da)
ES (1) ES2196456T3 (da)
HR (1) HRP980585B1 (da)
HU (1) HUP9802590A3 (da)
ID (1) ID21282A (da)
IL (1) IL126955A (da)
MY (1) MY115619A (da)
NO (1) NO312546B1 (da)
NZ (1) NZ332633A (da)
PL (1) PL329596A1 (da)
PT (1) PT915087E (da)
RU (1) RU2223951C2 (da)
SI (1) SI0915087T1 (da)
SK (1) SK283866B6 (da)
TR (1) TR199802270A2 (da)
TW (1) TW427970B (da)
ZA (1) ZA9810202B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1332943C (zh) 1998-07-08 2007-08-22 萨诺费－阿文蒂斯德国有限公司 硫取代的磺酰基氨基羧酸n－芳基酰胺,其制备方法、用途以及含有该化合物的药物制剂
DE19929076A1 (de) 1999-06-25 2000-12-28 Aventis Pharma Gmbh Indanylsubstituierte Benzolcarbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
AU781365B2 (en) * 1999-12-21 2005-05-19 Icagen, Inc. Potassium channel inhibitors
US6849634B2 (en) 2000-12-21 2005-02-01 Icagen Potassium channel inhibitors
PL370980A1 (en) * 2001-12-12 2005-06-13 F.Hoffmann-La Roche Ag Benzothiophenes as adenosine receptor modulators
US7119112B2 (en) * 2002-02-28 2006-10-10 Icagen, Inc. Sulfonamides as potassium channel blockers
JP4502280B2 (ja) * 2005-03-31 2010-07-14 塩野義製薬株式会社 スルファミンカルボン酸誘導体の製造方法
BRPI0706411A2 (pt) * 2006-01-24 2011-03-29 Lilly Co Eli composto, composição farmacêutica, método de preparação de um indol ou um sal farmaceuticamente aceitável do mesmo, e, uso de um composto
JP2009026126A (ja) * 2007-07-20 2009-02-05 Nec Electronics Corp 半導体装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3407842A1 (de) * 1983-03-04 1984-09-06 Otsuka Pharmaceutical Co. Ltd., Tokyo Indanderivate und deren salze, verfahren zu deren herstellung und arzneimittel und antioxidationsmittel, welche diese enthalten
DE3623944A1 (de) * 1986-07-16 1988-02-11 Thomae Gmbh Dr K Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof
US5877218A (en) * 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives

Also Published As

Publication number Publication date
EP0915087A3 (de) 1999-07-21
TW427970B (en) 2001-04-01
HU9802590D0 (en) 1999-01-28
SI0915087T1 (en) 2003-10-31
ID21282A (id) 1999-05-12
SK154598A3 (en) 1999-06-11
IL126955A (en) 2002-11-10
DE59807718D1 (de) 2003-05-08
CN1219533A (zh) 1999-06-16
HUP9802590A2 (hu) 2000-04-28
NZ332633A (en) 2000-05-26
KR19990045147A (ko) 1999-06-25
AU742199B2 (en) 2001-12-20
AU9139898A (en) 1999-05-27
ZA9810202B (en) 1999-05-10
CZ363798A3 (cs) 1999-05-12
US6015822A (en) 2000-01-18
RU2223951C2 (ru) 2004-02-20
HRP980585A2 (en) 1999-06-30
MY115619A (en) 2003-07-31
PT915087E (pt) 2003-08-29
TR199802270A2 (xx) 1999-05-21
IL126955A0 (en) 1999-09-22
JPH11236368A (ja) 1999-08-31
NO312546B1 (no) 2002-05-27
EP0915087B1 (de) 2003-04-02
NO985171D0 (no) 1998-11-05
CA2253211C (en) 2009-04-14
NO985171L (no) 1999-05-11
DE19749453A1 (de) 1999-05-12
BR9804995A (pt) 2001-05-22
SK283866B6 (sk) 2004-03-02
JP4331809B2 (ja) 2009-09-16
EP0915087A2 (de) 1999-05-12
AR016006A1 (es) 2001-05-30
HRP980585B1 (en) 2003-02-28
ES2196456T3 (es) 2003-12-16
CA2253211A1 (en) 1999-05-10
ATE236120T1 (de) 2003-04-15
PL329596A1 (en) 1999-05-24
HUP9802590A3 (en) 2001-08-28

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