DK0920426T3 - Hidtil ukendte thiazolderivater med phosphodiesteraseinhiberende virkning - Google Patents

Hidtil ukendte thiazolderivater med phosphodiesteraseinhiberende virkning

Info

Publication number: DK0920426T3
Authority: DK; Denmark
Prior art keywords: inhibitory effect; thiazole derivatives; pct; phosphodiesterase inhibitory; novel thiazole
Prior art date: 1996-08-26

Application number

DK97940080T

Other languages

English (en)

Inventor

Hermann Amschler

Thomas Martin

Beate Schmidt

Hildegard Boss

Thomas Baer

Wolf-Ruediger Ulrich

Dietrich Haefner

Dieter Flockerzi

Ulrich Thibaut

Armin Hatzelmann

Hans-Peter Kley

Rolf Beume

Original Assignee

Altana Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-26

Filing date

1997-08-13

Publication date

2004-02-02

1997-08-13 Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag

2004-02-02 Application granted granted Critical

2004-02-02 Publication of DK0920426T3 publication Critical patent/DK0920426T3/da

Links

102000004861 Phosphoric Diester Hydrolases Human genes 0.000 title 1
108090001050 Phosphoric Diester Hydrolases Proteins 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
150000007979 thiazole derivatives Chemical class 0.000 title 1
229940124639 Selective inhibitor Drugs 0.000 abstract 1
102000011017 Type 4 Cyclic Nucleotide Phosphodiesterases Human genes 0.000 abstract 1
108010037584 Type 4 Cyclic Nucleotide Phosphodiesterases Proteins 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK97940080T 1996-08-26 1997-08-13 Hidtil ukendte thiazolderivater med phosphodiesteraseinhiberende virkning DK0920426T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE19634411		1996-08-26
EP96113737		1996-08-28
PCT/EP1997/004435 WO1998008841A1 (de)	1996-08-26	1997-08-13	Neue thiazol-derivate mit phosphodiesterase inhibierender wirkung

Publications (1)

Publication Number	Publication Date
DK0920426T3 true DK0920426T3 (da)	2004-02-02

Family

ID=26028746

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97940080T DK0920426T3 (da)	1996-08-26	1997-08-13	Hidtil ukendte thiazolderivater med phosphodiesteraseinhiberende virkning

Country Status (12)

Country	Link
US (1)	US6011037A (da)
EP (1)	EP0920426B9 (da)
JP (1)	JP2000516940A (da)
AT (1)	ATE251153T1 (da)
AU (1)	AU4205197A (da)
CY (1)	CY2509B1 (da)
DE (1)	DE59710816D1 (da)
DK (1)	DK0920426T3 (da)
ES (1)	ES2208950T3 (da)
PT (1)	PT920426E (da)
SI (1)	SI0920426T1 (da)
WO (1)	WO1998008841A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1212089B1 (en)	1999-08-21	2006-03-22	ALTANA Pharma AG	Synergistic combination of roflumilast and salmeterol
IL160327A0 (en)	2001-08-13	2004-07-25	Janssen Pharmaceutica Nv	2,4,5-trisubstituted thiazolyl derivatives and their antiinflammatory activity
MXPA05010373A (es)	2003-04-01	2005-12-05	Applied Research Systems	Inhibidores de fosfodiesterasas en infertilidad.
EP2258358A3 (en)	2005-08-26	2011-09-07	Braincells, Inc.	Neurogenesis with acetylcholinesterase inhibitor
EP1928437A2 (en)	2005-08-26	2008-06-11	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation
EP1940389A2 (en)	2005-10-21	2008-07-09	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
US20070112017A1 (en)	2005-10-31	2007-05-17	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
EP1991212A1 (en) *	2006-03-08	2008-11-19	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
US20100009983A1 (en) *	2006-05-09	2010-01-14	Braincells, Inc.	5 ht receptor mediated neurogenesis
AU2007249399A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
WO2007134077A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	5 ht receptor mediated neurogenesis
EP2068872A1 (en) *	2006-09-08	2009-06-17	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative
AU2007299920A1 (en) *	2006-09-19	2008-03-27	Braincells, Inc.	PPAR Mediated Modulation of Neurogenesis
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
EP2707357B1 (en)	2011-05-10	2017-01-18	Merck Sharp & Dohme Corp.	Pyridyl aminopyridines as syk inhibitors
US9145391B2 (en)	2011-05-10	2015-09-29	Merck Sharp & Dohme Corp.	Bipyridylaminopyridines as Syk inhibitors
MX2013013090A (es) *	2011-05-10	2013-12-16	Merck Sharp & Dohme	Aminopirimidinas como inhibidores de tirosina cinaza del bazo.
WO2013106547A1 (en)	2012-01-10	2013-07-18	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0934937T3 (da) *	1990-11-30	2002-04-02	Otsuka Pharma Co Ltd	Azolderivater som superoxidradikalinhibitor
AU657413C (en) *	1992-05-29	2007-05-03	Otsuka Pharmaceutical Co., Ltd.	Thiazole derivatives for the release of superoxide radical
GB9315017D0 (en) *	1993-07-20	1993-09-01	Glaxo Lab Sa	Chemical compounds
EP0772606A1 (en) *	1994-07-27	1997-05-14	G.D. SEARLE & CO.	Substituted thiazoles for the treatment of inflammation

1997
- 1997-08-13 EP EP97940080A patent/EP0920426B9/de not_active Expired - Lifetime
- 1997-08-13 ES ES97940080T patent/ES2208950T3/es not_active Expired - Lifetime
- 1997-08-13 SI SI9730611T patent/SI0920426T1/xx unknown
- 1997-08-13 WO PCT/EP1997/004435 patent/WO1998008841A1/de not_active Ceased
- 1997-08-13 PT PT97940080T patent/PT920426E/pt unknown
- 1997-08-13 US US09/147,740 patent/US6011037A/en not_active Expired - Fee Related
- 1997-08-13 DE DE59710816T patent/DE59710816D1/de not_active Expired - Fee Related
- 1997-08-13 AU AU42051/97A patent/AU4205197A/en not_active Abandoned
- 1997-08-13 JP JP10511228A patent/JP2000516940A/ja active Pending
- 1997-08-13 DK DK97940080T patent/DK0920426T3/da active
- 1997-08-13 AT AT97940080T patent/ATE251153T1/de not_active IP Right Cessation
2005
- 2005-03-23 CY CY0500019A patent/CY2509B1/xx unknown

Also Published As

Publication number	Publication date
CY2509B1 (en)	2005-12-23
ES2208950T3 (es)	2004-06-16
JP2000516940A (ja)	2000-12-19
DE59710816D1 (de)	2003-11-06
US6011037A (en)	2000-01-04
EP0920426B1 (de)	2003-10-01
SI0920426T1 (en)	2004-04-30
ATE251153T1 (de)	2003-10-15
AU4205197A (en)	1998-03-19
WO1998008841A1 (de)	1998-03-05
PT920426E (pt)	2004-02-27
EP0920426B9 (de)	2005-04-06
EP0920426A1 (de)	1999-06-09

Publication	Publication Date	Title
DK0920426T3 (da)	2004-02-02	Hidtil ukendte thiazolderivater med phosphodiesteraseinhiberende virkning
ATE233247T1 (de)	2003-03-15	Phtalazinonen
ATE228507T1 (de)	2002-12-15	Substituierte 6-phenylphenanthridine
DE69115280D1 (de)	1996-01-18	Indolderivate, die die leukotrienbiosynthese hemmen.
SI1070056T1 (en)	2004-12-31	Phthalazinone pde iii/iv inhibitors
DK0937074T3 (da)	2003-06-23	Benzonaphthyridiner som bronkiale terapeutiske midler
ATE233252T1 (de)	2003-03-15	Substituierte dihydrobenzofurane als pde- hemmstoffe
DK1042319T3 (da)	2004-06-01	Dihydrobenzofuraner
SI1086096T1 (en)	2003-12-31	Benzamides with tetrahydrofuranyloxy substitutents as phosphodiesterase 4 inhibitors
DK1003724T3 (da)	2003-05-05	Substituerede quinolin-derivater med antiviral virkning
TW282458B (da)	1996-08-01
SI0937075T1 (en)	2004-06-30	New Imidazo- and Oxazolopyridines as Phosphodiesterase Inhibitors.