DK0928191T3 - Farmaceutiske præparater indeholdende S-alkylisothiouroniumderivater - Google Patents

Farmaceutiske præparater indeholdende S-alkylisothiouroniumderivater

Info

Publication number: DK0928191T3
Authority: DK; Denmark
Prior art keywords: pct; pharmaceuticals containing; sec; processes; date
Prior art date: 1996-09-26

Application number

DK97941178T

Other languages

English (en)

Inventor

V Evgeni Arzamastsev

I Lev Mizrakh

I Victor Gikavy

V Valentin Znamensky

B Lev Shagalov

Valeri Kovtun

H Vladimir Jashounsky

V Victor Darchuk

G Marina Kochetkova

I Galina Bondareva

A Olga Terekhova

Original Assignee

Meditor Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-26

Filing date

1997-09-25

Publication date

2002-12-30

1996-09-26 Priority claimed from RU96119163A external-priority patent/RU2142796C1/ru

1997-09-19 Priority claimed from RU97115433/14A external-priority patent/RU2187309C2/ru

1997-09-25 Application filed by Meditor Pharmaceuticals Ltd filed Critical Meditor Pharmaceuticals Ltd

2002-12-30 Application granted granted Critical

2002-12-30 Publication of DK0928191T3 publication Critical patent/DK0928191T3/da

Links

239000003814 drug Substances 0.000 title 1
208000032843 Hemorrhage Diseases 0.000 abstract 1
208000001953 Hypotension Diseases 0.000 abstract 1
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
208000011861 acute hypotension Diseases 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000222 hyperoxic effect Effects 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052698 phosphorus Inorganic materials 0.000 abstract 1
239000011574 phosphorus Substances 0.000 abstract 1
231100000572 poisoning Toxicity 0.000 abstract 1
230000000607 poisoning effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000035939 shock Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)

DK97941178T 1996-09-26 1997-09-25 Farmaceutiske præparater indeholdende S-alkylisothiouroniumderivater DK0928191T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
RU96119163A RU2142796C1 (ru)	1996-09-26	1996-09-26	Лекарственное противошоковое средство
RU97115433/14A RU2187309C2 (ru)	1997-09-19	1997-09-19	Средство, влияющее на артериальное давление
PCT/IL1997/000314 WO1998013036A1 (en)	1996-09-26	1997-09-25	Pharmaceutical compositions comprising s-alkylisothiouronium derivatives

Publications (1)

Publication Number	Publication Date
DK0928191T3 true DK0928191T3 (da)	2002-12-30

Family

ID=26653892

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97941178T DK0928191T3 (da)	1996-09-26	1997-09-25	Farmaceutiske præparater indeholdende S-alkylisothiouroniumderivater

Country Status (17)

Country	Link
US (1)	US6160008A (da)
EP (1)	EP0928191B1 (da)
JP (1)	JP4260888B2 (da)
KR (1)	KR100575507B1 (da)
CN (1)	CN1116871C (da)
AT (1)	ATE222758T1 (da)
AU (1)	AU717712B2 (da)
BR (1)	BR9712851A (da)
CA (1)	CA2266533C (da)
DE (1)	DE69715013T2 (da)
DK (1)	DK0928191T3 (da)
ES (1)	ES2182116T3 (da)
IL (1)	IL129020A (da)
NO (1)	NO326600B1 (da)
PT (1)	PT928191E (da)
TR (1)	TR199900783T2 (da)
WO (1)	WO1998013036A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1315505B1 (en) *	2000-09-05	2007-10-17	Meditor Pharmaceuticals Ltd.	Pharmaceutical compositions for headache, migraine, nausea and emesis
EA200800762A1 (ru) *	2005-09-06	2008-12-30	Медитор Фармасьютикалз Лтд.	Предотвращение гипотензии и стабилизация кровяного давления у гемодиализных пациентов
US20090186854A1 (en) *	2006-03-23	2009-07-23	Meditor Pharmaceuticals Ltd.	S-alkylisothiouronium derivatives for the treatment of inflammatory diseases
WO2008152619A1 (en) *	2007-06-13	2008-12-18	Meditor Pharmaceuticals Ltd.	Taste masked pharmaceutical compositions of s-alkylisothiouronium derivatives
US12011423B2 (en)	2007-11-06	2024-06-18	Foraviset Ltd.	S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
CN101917848B (zh) *	2007-11-06	2014-02-12	巴坎-法尔玛有限责任公司	用于治疗子宫收缩过强病症的s-烷基异硫脲衍生物
MD3619G2 (ro) *	2007-11-06	2009-01-31	Рафаэль Баркан	Remediu medicamentos nazal cu acţiune anticongestivă
CN104140386A (zh) *	2014-02-12	2014-11-12	上海应用技术学院	一种2-苄基-异硫脲三氟乙酸盐的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3123636A (en) *		1964-03-03		Thiuronium h alii
US3116327A (en) *	1960-07-22	1963-12-31	Baxter Laboratories Inc	Upsilon-dimethylaminopropyl isothiourea and acid addition salts thereof
US3657337A (en) *	1967-12-04	1972-04-18	Sandoz Ag	Benzylideneamino guanidines
FR2419675A1 (fr) *	1978-03-16	1979-10-12	Philagro Sa	Compositions fongicides a base de phosphites d'isothiouronium
AT395012B (de) *	1986-06-27	1992-08-25	Richter Gedeon Vegyeszet	Verfahren zur herstellung von n-(1(s)\|thoxycarbonyl-3-phenyl-propyl)-(s)-alanyl-(s)prolin und von dessen saeureadditionssalzen

1997
- 1997-09-25 PT PT97941178T patent/PT928191E/pt unknown
- 1997-09-25 CN CN97199137A patent/CN1116871C/zh not_active Expired - Fee Related
- 1997-09-25 TR TR1999/00783T patent/TR199900783T2/xx unknown
- 1997-09-25 EP EP97941178A patent/EP0928191B1/en not_active Expired - Lifetime
- 1997-09-25 IL IL12902097A patent/IL129020A/en not_active IP Right Cessation
- 1997-09-25 CA CA002266533A patent/CA2266533C/en not_active Expired - Fee Related
- 1997-09-25 BR BR9712851-1A patent/BR9712851A/pt not_active IP Right Cessation
- 1997-09-25 DK DK97941178T patent/DK0928191T3/da active
- 1997-09-25 US US09/269,405 patent/US6160008A/en not_active Expired - Fee Related
- 1997-09-25 ES ES97941178T patent/ES2182116T3/es not_active Expired - Lifetime
- 1997-09-25 WO PCT/IL1997/000314 patent/WO1998013036A1/en not_active Ceased
- 1997-09-25 JP JP51546498A patent/JP4260888B2/ja not_active Expired - Fee Related
- 1997-09-25 DE DE69715013T patent/DE69715013T2/de not_active Expired - Lifetime
- 1997-09-25 AT AT97941178T patent/ATE222758T1/de active
- 1997-09-25 KR KR1019997002578A patent/KR100575507B1/ko not_active Expired - Fee Related
- 1997-09-25 AU AU43178/97A patent/AU717712B2/en not_active Ceased
1999
- 1999-03-24 NO NO19991419A patent/NO326600B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE222758T1 (de)	2002-09-15
JP4260888B2 (ja)	2009-04-30
ES2182116T3 (es)	2003-03-01
WO1998013036A1 (en)	1998-04-02
EP0928191A1 (en)	1999-07-14
IL129020A (en)	2004-06-20
CN1116871C (zh)	2003-08-06
NO326600B1 (no)	2009-01-19
TR199900783T2 (xx)	1999-07-21
EP0928191B1 (en)	2002-08-28
DE69715013D1 (de)	2002-10-02
CA2266533C (en)	2007-08-07
CN1234737A (zh)	1999-11-10
IL129020A0 (en)	2000-02-17
CA2266533A1 (en)	1998-04-02
DE69715013T2 (de)	2003-05-22
BR9712851A (pt)	2000-01-18
HK1022833A1 (en)	2000-08-25
AU4317897A (en)	1998-04-17
US6160008A (en)	2000-12-12
KR20000048636A (ko)	2000-07-25
PT928191E (pt)	2003-01-31
NO991419D0 (no)	1999-03-24
JP2001501928A (ja)	2001-02-13
AU717712B2 (en)	2000-03-30
NO991419L (no)	1999-05-21
KR100575507B1 (ko)	2006-05-03

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KR900011887A (ko)	1990-08-02	효소 및 효소 안정화 시스템을 함유하는 액체 세제 조성물
DE3882078D1 (de)	1993-08-05	Amperometrische methode zur titration von nadh (1,4-dihydronicotinamid-adenine-dinucleotide) in loesung.
NO982721L (no)	1998-08-14	Preserverende oppl°sning
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DE69409649D1 (de)	1998-05-20	Nachweis von mikrobiellem wachstum
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ATE232191T1 (de)	2003-02-15	Verfahren und zusammensetzung zur inhibierung der polymerisierung von ethylenisch ungesättigten kohlenwasserstoffen
ES2195586T3 (es)	2003-12-01	Almidon modificado, estable respecto a la sal.
ATE211719T1 (de)	2002-01-15	Korrosionsinhibitoren enthaltender injektionszement
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ES2089091T3 (es)	1996-10-01	Complejos que contienen acidos s(+)-fenilalcanoicos y acidos alfa-hidroalcanoicos.
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