DK0928191T3 - Farmaceutiske præparater indeholdende S-alkylisothiouroniumderivater - Google Patents

Farmaceutiske præparater indeholdende S-alkylisothiouroniumderivater

Info

Publication number: DK0928191T3
Authority: DK; Denmark
Prior art keywords: pct; pharmaceuticals containing; sec; processes; date
Prior art date: 1996-09-26

Application number

DK97941178T

Other languages

Danish (da)

English (en)

Inventor

V Evgeni Arzamastsev

I Lev Mizrakh

I Victor Gikavy

V Valentin Znamensky

B Lev Shagalov

Valeri Kovtun

H Vladimir Jashounsky

V Victor Darchuk

G Marina Kochetkova

I Galina Bondareva

A Olga Terekhova

Original Assignee

Meditor Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-26

Filing date

1997-09-25

Publication date

2002-12-30

1996-09-26 Priority claimed from RU96119163A external-priority patent/RU2142796C1/ru

1997-09-19 Priority claimed from RU97115433/14A external-priority patent/RU2187309C2/ru

1997-09-25 Application filed by Meditor Pharmaceuticals Ltd filed Critical Meditor Pharmaceuticals Ltd

2002-12-30 Application granted granted Critical

2002-12-30 Publication of DK0928191T3 publication Critical patent/DK0928191T3/da

Links

239000003814 drug Substances 0.000 title 1
208000032843 Hemorrhage Diseases 0.000 abstract 1
208000001953 Hypotension Diseases 0.000 abstract 1
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
208000011861 acute hypotension Diseases 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000222 hyperoxic effect Effects 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052698 phosphorus Inorganic materials 0.000 abstract 1
239000011574 phosphorus Substances 0.000 abstract 1
231100000572 poisoning Toxicity 0.000 abstract 1
230000000607 poisoning effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000035939 shock Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Toxicology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Biochemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)

DK97941178T 1996-09-26 1997-09-25 Farmaceutiske præparater indeholdende S-alkylisothiouroniumderivater DK0928191T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
RU96119163A RU2142796C1 (ru)	1996-09-26	1996-09-26	Лекарственное противошоковое средство
RU97115433/14A RU2187309C2 (ru)	1997-09-19	1997-09-19	Средство, влияющее на артериальное давление
PCT/IL1997/000314 WO1998013036A1 (fr)	1996-09-26	1997-09-25	Compositions pharmaceutiques renfermant des derives de s-alkylisothiouronium

Publications (1)

Publication Number	Publication Date
DK0928191T3 true DK0928191T3 (da)	2002-12-30

Family

ID=26653892

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97941178T DK0928191T3 (da)	1996-09-26	1997-09-25	Farmaceutiske præparater indeholdende S-alkylisothiouroniumderivater

Country Status (17)

Country	Link
US (1)	US6160008A (fr)
EP (1)	EP0928191B1 (fr)
JP (1)	JP4260888B2 (fr)
KR (1)	KR100575507B1 (fr)
CN (1)	CN1116871C (fr)
AT (1)	ATE222758T1 (fr)
AU (1)	AU717712B2 (fr)
BR (1)	BR9712851A (fr)
CA (1)	CA2266533C (fr)
DE (1)	DE69715013T2 (fr)
DK (1)	DK0928191T3 (fr)
ES (1)	ES2182116T3 (fr)
IL (1)	IL129020A (fr)
NO (1)	NO326600B1 (fr)
PT (1)	PT928191E (fr)
TR (1)	TR199900783T2 (fr)
WO (1)	WO1998013036A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2420410C (fr)	2000-09-05	2011-04-26	Meditor Pharmaceuticals Ltd.	Compositions pharmaceutiques contre les cephalees, la migraine, les nausees et les vomissements
WO2007029255A1 (fr) *	2005-09-06	2007-03-15	Meditor Pharmaceuticals Ltd.	Prevention de l'hypotension et stabilisation de la pression sanguine chez des patients hemodialyses
US20090186854A1 (en) *	2006-03-23	2009-07-23	Meditor Pharmaceuticals Ltd.	S-alkylisothiouronium derivatives for the treatment of inflammatory diseases
EP2167050A1 (fr) *	2007-06-13	2010-03-31	Meditor Pharmaceuticals Ltd.	Compositions pharmaceutiques à goût masqué de dérivés de s-alkylisothiuronium
MD3619G2 (ro) *	2007-11-06	2009-01-31	Рафаэль Баркан	Remediu medicamentos nazal cu acţiune anticongestivă
EA030035B1 (ru) *	2007-11-06	2018-06-29	Меламед, Лемуил	Применение s-этилизотиоурония диэтилфосфата для изготовления лекарственного средства для лечения нарушения матки
US12011423B2 (en)	2007-11-06	2024-06-18	Foraviset Ltd.	S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
CN104140386A (zh) *	2014-02-12	2014-11-12	上海应用技术学院	一种2-苄基-异硫脲三氟乙酸盐的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3123636A (en) *		1964-03-03		Thiuronium h alii
US3116327A (en) *	1960-07-22	1963-12-31	Baxter Laboratories Inc	Upsilon-dimethylaminopropyl isothiourea and acid addition salts thereof
US3657337A (en) *	1967-12-04	1972-04-18	Sandoz Ag	Benzylideneamino guanidines
FR2419675A1 (fr) *	1978-03-16	1979-10-12	Philagro Sa	Compositions fongicides a base de phosphites d'isothiouronium
AT395012B (de) *	1986-06-27	1992-08-25	Richter Gedeon Vegyeszet	Verfahren zur herstellung von n-(1(s)\|thoxycarbonyl-3-phenyl-propyl)-(s)-alanyl-(s)prolin und von dessen saeureadditionssalzen

1997
- 1997-09-25 WO PCT/IL1997/000314 patent/WO1998013036A1/fr not_active Ceased
- 1997-09-25 AT AT97941178T patent/ATE222758T1/de active
- 1997-09-25 CN CN97199137A patent/CN1116871C/zh not_active Expired - Fee Related
- 1997-09-25 PT PT97941178T patent/PT928191E/pt unknown
- 1997-09-25 EP EP97941178A patent/EP0928191B1/fr not_active Expired - Lifetime
- 1997-09-25 BR BR9712851-1A patent/BR9712851A/pt not_active IP Right Cessation
- 1997-09-25 US US09/269,405 patent/US6160008A/en not_active Expired - Fee Related
- 1997-09-25 DK DK97941178T patent/DK0928191T3/da active
- 1997-09-25 KR KR1019997002578A patent/KR100575507B1/ko not_active Expired - Fee Related
- 1997-09-25 JP JP51546498A patent/JP4260888B2/ja not_active Expired - Fee Related
- 1997-09-25 ES ES97941178T patent/ES2182116T3/es not_active Expired - Lifetime
- 1997-09-25 TR TR1999/00783T patent/TR199900783T2/xx unknown
- 1997-09-25 IL IL12902097A patent/IL129020A/en not_active IP Right Cessation
- 1997-09-25 AU AU43178/97A patent/AU717712B2/en not_active Ceased
- 1997-09-25 DE DE69715013T patent/DE69715013T2/de not_active Expired - Lifetime
- 1997-09-25 CA CA002266533A patent/CA2266533C/fr not_active Expired - Fee Related
1999
- 1999-03-24 NO NO19991419A patent/NO326600B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20000048636A (ko)	2000-07-25
NO326600B1 (no)	2009-01-19
TR199900783T2 (xx)	1999-07-21
CA2266533C (fr)	2007-08-07
NO991419L (no)	1999-05-21
BR9712851A (pt)	2000-01-18
DE69715013T2 (de)	2003-05-22
US6160008A (en)	2000-12-12
AU4317897A (en)	1998-04-17
PT928191E (pt)	2003-01-31
CN1234737A (zh)	1999-11-10
KR100575507B1 (ko)	2006-05-03
DE69715013D1 (de)	2002-10-02
JP4260888B2 (ja)	2009-04-30
ES2182116T3 (es)	2003-03-01
JP2001501928A (ja)	2001-02-13
IL129020A0 (en)	2000-02-17
HK1022833A1 (en)	2000-08-25
CN1116871C (zh)	2003-08-06
CA2266533A1 (fr)	1998-04-02
EP0928191B1 (fr)	2002-08-28
NO991419D0 (no)	1999-03-24
ATE222758T1 (de)	2002-09-15
AU717712B2 (en)	2000-03-30
IL129020A (en)	2004-06-20
EP0928191A1 (fr)	1999-07-14
WO1998013036A1 (fr)	1998-04-02

Publication	Publication Date	Title
DE69506882D1 (de)	1999-02-04	Wasserlösliche organische salze von kreatin
ATE345682T1 (de)	2006-12-15	In vitro verfahren zum einbringen von nukleinsäuren in eine zelle
GB9312508D0 (en)	1993-08-04	Compounds
AR021777A1 (es)	2002-08-07	UNA COMPOSICIoN PARA ACONDICIONAR, ACLARAR E ILUMINAR EL CABELLO Y UN MÉTODO PARA ACONDICIONAR, ACLARAR E ILUMINAR EL CABELLO.
ATE174065T1 (de)	1998-12-15	Simultane sequenzierung von nukleinsäuren
ATE268750T1 (de)	2004-06-15	Proteintyrosinphosphatase inhibitoren
DK0378262T3 (da)	1994-02-07	Flydende detergentsammensætning indeholdende et enzym og et enzymstabiliseringssystem
DE3882078D1 (de)	1993-08-05	Amperometrische methode zur titration von nadh (1,4-dihydronicotinamid-adenine-dinucleotide) in loesung.
DK0928191T3 (da)	2002-12-30	Farmaceutiske præparater indeholdende S-alkylisothiouroniumderivater
ES2117976T3 (es)	1998-09-01	Preparacion de derivados n-acetil neuraminicos.
DE69409649D1 (de)	1998-05-20	Nachweis von mikrobiellem wachstum
ATE232191T1 (de)	2003-02-15	Verfahren und zusammensetzung zur inhibierung der polymerisierung von ethylenisch ungesättigten kohlenwasserstoffen
ES2195586T3 (es)	2003-12-01	Almidon modificado, estable respecto a la sal.
ATE211719T1 (de)	2002-01-15	Korrosionsinhibitoren enthaltender injektionszement
EA200000522A1 (ru)	2000-10-30	5-htагонисты
ATE200805T1 (de)	2001-05-15	Verfahren zur reduktion von schwefel- und küpenfarbstoffen
DE69330465D1 (de)	2001-08-23	Verfahren zur behandlung von chronischer prostatitis mit 17-beta-n-tertbutylcarbamoyl-4-aza-5 alpha-androst-1-en-3-one
DE69520947D1 (de)	2001-06-21	Diarinopropanole abgeleitet von aminosäuren
ATE445021T1 (de)	2009-10-15	Reduktion von kreuzkontaminationen bei nukleinsäureamplifikationen
DE59611397D1 (de)	2006-12-14	Verfahren zur bekämpfung von fischmycosen und einzelligen ektoparasiten
ES2089091T3 (es)	1996-10-01	Complejos que contienen acidos s(+)-fenilalcanoicos y acidos alfa-hidroalcanoicos.
BR9807920A (pt)	2000-02-22	Processos para tratamento de uma demência em um sujeito e para prevenção de uma demência
FI940830A0 (fi)	1994-02-22	Menetelmä nopeasti hybridisoituvien, yksijuosteisten polynukleotidien tunnistamiseksi
TH20631A (fr)	1996-09-17