DK0929677T3 - Rekombinant fremgangsmåde til fremstilling af et fuldstændigt malaria-antigen GP190/MSP1 - Google Patents

Rekombinant fremgangsmåde til fremstilling af et fuldstændigt malaria-antigen GP190/MSP1

Info

Publication number
DK0929677T3
DK0929677T3 DK97911173T DK97911173T DK0929677T3 DK 0929677 T3 DK0929677 T3 DK 0929677T3 DK 97911173 T DK97911173 T DK 97911173T DK 97911173 T DK97911173 T DK 97911173T DK 0929677 T3 DK0929677 T3 DK 0929677T3
Authority
DK
Denmark
Prior art keywords
msp1
producing
complete
recombinant method
malaria antigen
Prior art date
Application number
DK97911173T
Other languages
English (en)
Inventor
Hermann Bujard
Ralf Tolle
Weiqing Pan
Original Assignee
Hermann Bujard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hermann Bujard filed Critical Hermann Bujard
Application granted granted Critical
Publication of DK0929677T3 publication Critical patent/DK0929677T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK97911173T 1996-10-02 1997-10-02 Rekombinant fremgangsmåde til fremstilling af et fuldstændigt malaria-antigen GP190/MSP1 DK0929677T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19640817A DE19640817A1 (de) 1996-10-02 1996-10-02 Rekombinantes Herstellungsverfahren für ein vollständiges Malaria-Antigen gp190/MSP 1

Publications (1)

Publication Number Publication Date
DK0929677T3 true DK0929677T3 (da) 2005-11-14

Family

ID=7807776

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97911173T DK0929677T3 (da) 1996-10-02 1997-10-02 Rekombinant fremgangsmåde til fremstilling af et fuldstændigt malaria-antigen GP190/MSP1

Country Status (11)

Country Link
US (2) US6933130B1 (da)
EP (2) EP1637602A1 (da)
JP (1) JP2000516477A (da)
CN (1) CN1148448C (da)
AT (1) ATE299939T1 (da)
AU (1) AU727864B2 (da)
DE (2) DE19640817A1 (da)
DK (1) DK0929677T3 (da)
ES (1) ES2244993T3 (da)
ID (1) ID22037A (da)
WO (1) WO1998014583A2 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999020766A2 (en) 1997-10-20 1999-04-29 Genzyme Transgenics Corporation NOVEL MODIFIED NUCLEIC ACID SEQUENCES AND METHODS FOR INCREASING mRNA LEVELS AND PROTEIN EXPRESSION IN CELL SYSTEMS
WO2001066776A2 (de) * 2000-03-10 2001-09-13 Institut für Molekulare Biotechnologie E.V. Neuartige l-form-bakterienstämme, verfahren zu deren herstellung sowie deren verwendung zur herstellung von genprodukten
CN1176945C (zh) * 2001-02-01 2004-11-24 中国人民解放军第二军医大学 疟原虫融合抗原及其制法和用途
US20040005600A1 (en) * 2002-04-01 2004-01-08 Evelina Angov Method of designing synthetic nucleic acid sequences for optimal protein expression in a host cell
DE10249390A1 (de) * 2002-10-23 2004-05-13 Ruprecht-Karls-Universität Heidelberg Rekombinante MVA-Stämme als potentielle Impfstoffe gegen P.falciparum-Malaria
US7928215B2 (en) 2002-11-22 2011-04-19 Eisai R&D Management Co., Ltd. Methods of screening for compounds that inhibit the biosynthesis of GPI in malaria parasites
EP1649869A1 (en) * 2004-10-21 2006-04-26 Vakzine Projekt Management GmbH Combination of a recombinant mycobacterium and a biologically active agent as a vaccine
EP2431469A3 (en) * 2006-05-15 2012-05-30 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
WO2008059314A1 (es) * 2006-11-14 2008-05-22 Centro Internacional De Vacunas Vacuna contra la malaria, basada en la subunidad 200l de la proteína msp1 de plasmodium vivax
EP1944313A1 (en) * 2007-01-15 2008-07-16 Vakzine Projekt Management GmbH Recombinant malaria vaccine
EP2141177A1 (en) * 2008-07-04 2010-01-06 Bujard, Hermann MSP-1 protein preparations from Plasmodium
US8501926B2 (en) * 2008-09-24 2013-08-06 The Johns Hopkins University Malaria vaccine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2154592A (en) * 1984-02-22 1985-09-11 Wellcome Found Cloning of a malarial gene
US4978621A (en) * 1985-09-03 1990-12-18 Scripps Clinic And Research Foundation Merozoite surface antigens
WO1988000595A1 (en) * 1986-07-17 1988-01-28 Saramane Pty. Ltd. Merozoite surface antigen of plasmodium falciparum
US4897354A (en) * 1986-07-28 1990-01-30 University Of Hawaii Monoclonal antibody-specific merozoite antigens
GB8810808D0 (en) * 1988-05-06 1988-06-08 Wellcome Found Vectors
NZ230375A (en) 1988-09-09 1991-07-26 Lubrizol Genetics Inc Synthetic gene encoding b. thuringiensis insecticidal protein
CA2024811A1 (en) 1989-02-24 1990-08-25 David A. Fischhoff Synthetic plant genes and method for preparation
US5766597A (en) * 1991-03-07 1998-06-16 Virogenetics Corporation Malaria recombinant poxviruses
JPH06505397A (ja) * 1991-03-20 1994-06-23 ヴァイロジェネティクス　コーポレイション マラリア組換体ポックスウイルス

Also Published As

Publication number Publication date
DE59712370D1 (de) 2005-08-25
EP0929677B1 (de) 2005-07-20
US6933130B1 (en) 2005-08-23
EP0929677A2 (de) 1999-07-21
ES2244993T3 (es) 2005-12-16
WO1998014583A2 (de) 1998-04-09
ATE299939T1 (de) 2005-08-15
JP2000516477A (ja) 2000-12-12
CN1236391A (zh) 1999-11-24
AU727864B2 (en) 2001-01-04
CN1148448C (zh) 2004-05-05
DE19640817A1 (de) 1998-05-14
ID22037A (id) 1999-08-26
EP1637602A1 (de) 2006-03-22
AU4864997A (en) 1998-04-24
US20050095256A1 (en) 2005-05-05

Similar Documents

Publication Publication Date Title
DK0929677T3 (da) Rekombinant fremgangsmåde til fremstilling af et fuldstændigt malaria-antigen GP190/MSP1
GR3022403T3 (en) RNA catalyst for cleaving specific RNA sequences
WO2002032962A3 (en) Compositions of human proteins and method of use thereof
WO2001062794A3 (en) 18607, a human calcium channel
EP0804609A4 (en) NEW GENES OF RESPONSE p53
WO2002014358A3 (en) Novel secreted proteins and their uses
DK1187852T3 (da) Ekspression og eksport af interferon-alpha-proteiner som Fc-fusionsproteiner
WO2001072976A3 (en) 32142, 21481, 25964, 21686, novel human dehydrogenase molecules and uses therefor
ES2002467A6 (es) Procedimiento para la preparacion de un antigeno peptido inmunogenico correspondiente a la proteina circumsporozoito de plasmodium vivax
WO2002008277A3 (en) Nucleic acids, vectors, host cells, polypeptides, and uses thereof
WO2002000722A3 (en) Human calcium channels (48000; 52920) and uses thereof
EP2044950A3 (en) Attenuated VIF DNA immunization cassettes for genetic vaccines
GB0118532D0 (en) Materials and methods relating to improved vaccination strategies
AU2992489A (en) Method for producing recombinant protein derived from the circumsporozoite gene of plasmodium falciparum
AU2001238064A1 (en) 18477, a human protein kinase and uses therefor
WO2001092493A3 (en) 21956 and 25856, human aminopeptidases and uses thereof
EE03074B1 (et) Rekombinantsed eukarüootsed rakud, nende saamiseks vajalikud DNA järjestused, meetod eukarüootsete rakkude konstrueerimiseks ja sekreteeritavate valkude ning biomassi tootmismeetod
WO2002074960A3 (en) 38650, 28472, 5495, 65507, 81588 and 14354 methods and compositions of human proteins and uses thereof
WO2002016578A3 (en) Secreted proteins and methods of using same
WO2001075076A3 (en) 33167, a novel human hydrolase and uses therefor
AU2001253258A1 (en) Human trp-like calcium channel protein-2 (tlcc-2)
MXPA01011563A (es) Una novedosa proteina 5 relacionada al factro-h y anticuerpos relacionados.
WO2001096542A3 (en) A human aminotransferase (23680) and uses thereof
WO2001079293A3 (en) Human cadherin molecules and uses therefor
EP1241186A3 (en) Human growth arrest specific gene 6 (gas-6) and nucleic acids encoding the same