DK0953563T3 - Fremgangsmåde til fremstilling af depsipeptidderivater samt hidtil ukendte intermediater derfor - Google Patents

Fremgangsmåde til fremstilling af depsipeptidderivater samt hidtil ukendte intermediater derfor

Info

Publication number
DK0953563T3
DK0953563T3 DK97941241T DK97941241T DK0953563T3 DK 0953563 T3 DK0953563 T3 DK 0953563T3 DK 97941241 T DK97941241 T DK 97941241T DK 97941241 T DK97941241 T DK 97941241T DK 0953563 T3 DK0953563 T3 DK 0953563T3
Authority
DK
Denmark
Prior art keywords
preparing
well
novel intermediates
intermediates therefor
derivatives
Prior art date
Application number
DK97941241T
Other languages
Danish (da)
English (en)
Inventor
Ryo Yamanishi
Masaru Ohgaki
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of DK0953563T3 publication Critical patent/DK0953563T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D273/00Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/12Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97941241T 1996-10-07 1997-09-24 Fremgangsmåde til fremstilling af depsipeptidderivater samt hidtil ukendte intermediater derfor DK0953563T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28604796 1996-10-07
PCT/JP1997/003417 WO1998015523A1 (fr) 1996-10-07 1997-09-24 Procede de production de derives de depsideptides et leurs nouveaux intermediaires

Publications (1)

Publication Number Publication Date
DK0953563T3 true DK0953563T3 (da) 2003-07-28

Family

ID=17699289

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97941241T DK0953563T3 (da) 1996-10-07 1997-09-24 Fremgangsmåde til fremstilling af depsipeptidderivater samt hidtil ukendte intermediater derfor

Country Status (12)

Country Link
US (1) US6235875B1 (fr)
EP (1) EP0953563B1 (fr)
JP (1) JP4035852B2 (fr)
CN (1) CN1205177C (fr)
AT (1) ATE237583T1 (fr)
BR (1) BR9712279A (fr)
CA (1) CA2267376C (fr)
DE (1) DE69721055T2 (fr)
DK (1) DK0953563T3 (fr)
ES (1) ES2191852T3 (fr)
PT (1) PT953563E (fr)
WO (1) WO1998015523A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ504812A (en) * 1997-11-10 2002-08-28 Fujisawa Pharmaceutical Co A crystal of a phenyl-morpholino substituted depsipeptide derivative
WO2006055621A2 (fr) * 2004-11-17 2006-05-26 The University Of Chicago Inhibiteurs de l'histone desacetylase et leurs methodes d'utilisation
CN107835818B (zh) 2015-05-20 2022-04-29 勃林格殷格翰动物保健美国公司 驱虫缩酚酸肽化合物
BR112018013369A2 (pt) 2015-12-28 2019-02-19 Merial, Inc. compostos depsipeptídicos anti-helmínticos
EP3541789A1 (fr) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Composés depsipeptidiques anthelminthiques

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ249588A (en) 1992-03-17 1996-08-27 Fujisawa Pharmaceutical Co Anthelmintic agent
DE4317432A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
DE4317457A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
NZ271739A (en) 1993-09-06 1996-09-25 Fujisawa Pharmaceutical Co Cyclodepsipeptide compounds and pharmaceutical compositions thereof
ATE425973T1 (de) 1995-06-30 2009-04-15 Astellas Pharma Inc Depsipeptid-derivat, verfahren zu dessen herstellung und zwischenprodukt dafur

Also Published As

Publication number Publication date
PT953563E (pt) 2003-08-29
DE69721055D1 (de) 2003-05-22
CA2267376C (fr) 2006-11-14
JP4035852B2 (ja) 2008-01-23
US6235875B1 (en) 2001-05-22
DE69721055T2 (de) 2004-02-19
CN1232446A (zh) 1999-10-20
EP0953563B1 (fr) 2003-04-16
EP0953563A1 (fr) 1999-11-03
WO1998015523A1 (fr) 1998-04-16
BR9712279A (pt) 1999-08-31
CA2267376A1 (fr) 1998-04-16
EP0953563A4 (fr) 2001-05-16
ES2191852T3 (es) 2003-09-16
ATE237583T1 (de) 2003-05-15
CN1205177C (zh) 2005-06-08

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