DK0970247T3 - Påvisning af DNA-beskadigende midler - Google Patents
Påvisning af DNA-beskadigende midlerInfo
- Publication number
- DK0970247T3 DK0970247T3 DK98913889T DK98913889T DK0970247T3 DK 0970247 T3 DK0970247 T3 DK 0970247T3 DK 98913889 T DK98913889 T DK 98913889T DK 98913889 T DK98913889 T DK 98913889T DK 0970247 T3 DK0970247 T3 DK 0970247T3
- Authority
- DK
- Denmark
- Prior art keywords
- dna
- detection
- damaging agents
- regulatory element
- dna molecules
- Prior art date
Links
- 239000012623 DNA damaging agent Substances 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 108020004414 DNA Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 1
- 230000033616 DNA repair Effects 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 231100000024 genotoxic Toxicity 0.000 abstract 1
- 230000001738 genotoxic effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5032—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on intercellular interactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
- C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Plant Pathology (AREA)
- General Physics & Mathematics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9706414.1A GB9706414D0 (en) | 1997-03-27 | 1997-03-27 | Detection of DNA damage |
| EP98913889A EP0970247B1 (fr) | 1997-03-27 | 1998-03-27 | Detection de facteurs de dommage a l'adn |
| PCT/GB1998/000786 WO1998044149A1 (fr) | 1997-03-27 | 1998-03-27 | Detection de facteurs de dommage a l'adn |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0970247T3 true DK0970247T3 (da) | 2004-11-29 |
Family
ID=10809987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98913889T DK0970247T3 (da) | 1997-03-27 | 1998-03-27 | Påvisning af DNA-beskadigende midler |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6489099B1 (fr) |
| EP (2) | EP0970247B1 (fr) |
| JP (1) | JP4163757B2 (fr) |
| AT (1) | ATE271615T1 (fr) |
| AU (1) | AU747297B2 (fr) |
| CA (1) | CA2285703C (fr) |
| DE (1) | DE69825152T2 (fr) |
| DK (1) | DK0970247T3 (fr) |
| ES (1) | ES2226118T3 (fr) |
| GB (1) | GB9706414D0 (fr) |
| WO (1) | WO1998044149A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPP438598A0 (en) | 1998-06-29 | 1998-07-23 | Garvan Institute Of Medical Research | NPY-Y7 receptor gene |
| US6509161B1 (en) | 2000-02-29 | 2003-01-21 | Gentronix Limited | Green fluorescent protein |
| JP2007500506A (ja) * | 2003-07-31 | 2007-01-18 | ジェントロニクス・リミテッド | 遺伝子毒性試験法 |
| GB0411198D0 (en) * | 2004-05-20 | 2004-06-23 | Gentronix Ltd | Genotoxic testing |
| US8969008B2 (en) | 2004-05-20 | 2015-03-03 | Gentronix Limited | Genotoxic testing |
| JP2006101705A (ja) * | 2004-09-30 | 2006-04-20 | Olympus Corp | 細胞内小核の検出方法 |
| US20080187927A1 (en) * | 2006-11-12 | 2008-08-07 | Palecek Sean P | Using hug1 promoter and a reporter gene to detect genotoxicity and genoprotection |
| GB0921712D0 (en) | 2009-12-11 | 2010-01-27 | Ge Healthcare Uk Ltd | Methods of detecting DNA damage |
| EP4069731A4 (fr) | 2019-12-03 | 2024-05-29 | Alamar Biosciences, Inc. | Dosage immunologique-sandwich lié à un acide nucléique (nulisa) |
| CN115575369B (zh) * | 2022-10-14 | 2025-10-28 | 中国药科大学 | 一种用于消化道内亚硝胺类化合物监测的金属有机配位凝胶保护的全细胞生物传感器 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL75210A0 (en) | 1984-05-22 | 1985-09-29 | Bioteknika International | Yeast vector |
| HK1004920A1 (en) * | 1993-01-21 | 1998-12-11 | President And Fellows Of Harvard College | Methods and diagnostic kits utilizing mammalian stress promoters to determine toxicity of a compound |
| EP0759170B1 (fr) * | 1993-09-10 | 2008-07-09 | The Trustees Of Columbia University In The City Of New York | Methodes d'utilisation de protéine fluorescente verte |
-
1997
- 1997-03-27 GB GBGB9706414.1A patent/GB9706414D0/en active Pending
-
1998
- 1998-03-27 EP EP98913889A patent/EP0970247B1/fr not_active Expired - Lifetime
- 1998-03-27 EP EP04077056A patent/EP1561822A1/fr not_active Withdrawn
- 1998-03-27 JP JP54127198A patent/JP4163757B2/ja not_active Expired - Fee Related
- 1998-03-27 US US09/381,989 patent/US6489099B1/en not_active Expired - Fee Related
- 1998-03-27 DK DK98913889T patent/DK0970247T3/da active
- 1998-03-27 CA CA2285703A patent/CA2285703C/fr not_active Expired - Fee Related
- 1998-03-27 WO PCT/GB1998/000786 patent/WO1998044149A1/fr not_active Ceased
- 1998-03-27 DE DE69825152T patent/DE69825152T2/de not_active Expired - Lifetime
- 1998-03-27 ES ES98913889T patent/ES2226118T3/es not_active Expired - Lifetime
- 1998-03-27 AU AU68419/98A patent/AU747297B2/en not_active Ceased
- 1998-03-27 AT AT98913889T patent/ATE271615T1/de not_active IP Right Cessation
-
2002
- 2002-09-16 US US10/244,292 patent/US7049071B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2285703A1 (fr) | 1998-10-08 |
| DE69825152T2 (de) | 2005-08-11 |
| US20030049690A1 (en) | 2003-03-13 |
| DE69825152D1 (de) | 2004-08-26 |
| ES2226118T3 (es) | 2005-03-16 |
| CA2285703C (fr) | 2011-02-08 |
| WO1998044149A1 (fr) | 1998-10-08 |
| US7049071B2 (en) | 2006-05-23 |
| EP0970247A1 (fr) | 2000-01-12 |
| ATE271615T1 (de) | 2004-08-15 |
| AU6841998A (en) | 1998-10-22 |
| AU747297B2 (en) | 2002-05-16 |
| US6489099B1 (en) | 2002-12-03 |
| JP4163757B2 (ja) | 2008-10-08 |
| EP0970247B1 (fr) | 2004-07-21 |
| JP2001517083A (ja) | 2001-10-02 |
| EP1561822A1 (fr) | 2005-08-10 |
| GB9706414D0 (en) | 1997-05-14 |
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