DK0970247T3 - Påvisning af DNA-beskadigende midler - Google Patents

Påvisning af DNA-beskadigende midler

Info

Publication number
DK0970247T3
DK0970247T3 DK98913889T DK98913889T DK0970247T3 DK 0970247 T3 DK0970247 T3 DK 0970247T3 DK 98913889 T DK98913889 T DK 98913889T DK 98913889 T DK98913889 T DK 98913889T DK 0970247 T3 DK0970247 T3 DK 0970247T3
Authority
DK
Denmark
Prior art keywords
dna
detection
damaging agents
regulatory element
dna molecules
Prior art date
Application number
DK98913889T
Other languages
Danish (da)
English (en)
Inventor
Richard Maurice Walmsley
Wolf Heyer
Original Assignee
Gentronix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10809987&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0970247(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gentronix Ltd filed Critical Gentronix Ltd
Application granted granted Critical
Publication of DK0970247T3 publication Critical patent/DK0970247T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5032Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on intercellular interactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK98913889T 1997-03-27 1998-03-27 Påvisning af DNA-beskadigende midler DK0970247T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9706414.1A GB9706414D0 (en) 1997-03-27 1997-03-27 Detection of DNA damage
EP98913889A EP0970247B1 (fr) 1997-03-27 1998-03-27 Detection de facteurs de dommage a l'adn
PCT/GB1998/000786 WO1998044149A1 (fr) 1997-03-27 1998-03-27 Detection de facteurs de dommage a l'adn

Publications (1)

Publication Number Publication Date
DK0970247T3 true DK0970247T3 (da) 2004-11-29

Family

ID=10809987

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98913889T DK0970247T3 (da) 1997-03-27 1998-03-27 Påvisning af DNA-beskadigende midler

Country Status (11)

Country Link
US (2) US6489099B1 (fr)
EP (2) EP0970247B1 (fr)
JP (1) JP4163757B2 (fr)
AT (1) ATE271615T1 (fr)
AU (1) AU747297B2 (fr)
CA (1) CA2285703C (fr)
DE (1) DE69825152T2 (fr)
DK (1) DK0970247T3 (fr)
ES (1) ES2226118T3 (fr)
GB (1) GB9706414D0 (fr)
WO (1) WO1998044149A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP438598A0 (en) 1998-06-29 1998-07-23 Garvan Institute Of Medical Research NPY-Y7 receptor gene
US6509161B1 (en) 2000-02-29 2003-01-21 Gentronix Limited Green fluorescent protein
JP2007500506A (ja) * 2003-07-31 2007-01-18 ジェントロニクス・リミテッド 遺伝子毒性試験法
GB0411198D0 (en) * 2004-05-20 2004-06-23 Gentronix Ltd Genotoxic testing
US8969008B2 (en) 2004-05-20 2015-03-03 Gentronix Limited Genotoxic testing
JP2006101705A (ja) * 2004-09-30 2006-04-20 Olympus Corp 細胞内小核の検出方法
US20080187927A1 (en) * 2006-11-12 2008-08-07 Palecek Sean P Using hug1 promoter and a reporter gene to detect genotoxicity and genoprotection
GB0921712D0 (en) 2009-12-11 2010-01-27 Ge Healthcare Uk Ltd Methods of detecting DNA damage
EP4069731A4 (fr) 2019-12-03 2024-05-29 Alamar Biosciences, Inc. Dosage immunologique-sandwich lié à un acide nucléique (nulisa)
CN115575369B (zh) * 2022-10-14 2025-10-28 中国药科大学 一种用于消化道内亚硝胺类化合物监测的金属有机配位凝胶保护的全细胞生物传感器

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL75210A0 (en) 1984-05-22 1985-09-29 Bioteknika International Yeast vector
HK1004920A1 (en) * 1993-01-21 1998-12-11 President And Fellows Of Harvard College Methods and diagnostic kits utilizing mammalian stress promoters to determine toxicity of a compound
EP0759170B1 (fr) * 1993-09-10 2008-07-09 The Trustees Of Columbia University In The City Of New York Methodes d'utilisation de protéine fluorescente verte

Also Published As

Publication number Publication date
CA2285703A1 (fr) 1998-10-08
DE69825152T2 (de) 2005-08-11
US20030049690A1 (en) 2003-03-13
DE69825152D1 (de) 2004-08-26
ES2226118T3 (es) 2005-03-16
CA2285703C (fr) 2011-02-08
WO1998044149A1 (fr) 1998-10-08
US7049071B2 (en) 2006-05-23
EP0970247A1 (fr) 2000-01-12
ATE271615T1 (de) 2004-08-15
AU6841998A (en) 1998-10-22
AU747297B2 (en) 2002-05-16
US6489099B1 (en) 2002-12-03
JP4163757B2 (ja) 2008-10-08
EP0970247B1 (fr) 2004-07-21
JP2001517083A (ja) 2001-10-02
EP1561822A1 (fr) 2005-08-10
GB9706414D0 (en) 1997-05-14

Similar Documents

Publication Publication Date Title
DK0971946T3 (da) Selektion af proteiner ved anvendelse af RNA-protein-fusioner
ES2149149T1 (es) Proteinas de fijacion de interleuquina-18, su preparacion y utilizacion.
ATE353965T1 (de) An g-protein gekoppelte rezeptoren und deren verwendungen
DK0929564T3 (da) Höjniveau-ekspression af proteiner
DK0851868T3 (da) Höjniveau-ekspression af proteiner
ATE454393T1 (de) Egvii-endoglucanase und dafür codierende nukleinsäuren
DK0970247T3 (da) Påvisning af DNA-beskadigende midler
DE69736177D1 (de) Mit aminosäuren stabilisierte erythropoietinlösung
CY1110868T1 (el) Ελαχιστη αλληλουχια dna που δρα ως μονωτης της χρωματινης και η χρηση της στην πρωτεϊνικη εκφραση
DK2316940T3 (da) Fokuserede biblioteker af genpakker
CY1106350T1 (el) Εμβολιο φυματιωσης
DE69931507D1 (de) Interferon-beta fusionsproteine und deren verwendungen
AR038568A1 (es) Anticuerpos anti-a beta y su uso
DE60234131D1 (de) Neue fusionsproteine und molekulare bindungsassays
DE69131580D1 (de) GDF-1 und UOG1 Proteine
EA200000144A1 (ru) Направленный цитолиз клеток-мишеней, агенты и композиции, вызывающие цитолиз, и соединения, которые можно использовать для получения этих агентов
DE50112802D1 (de) Peptide, deren herstellung und verwendung zur bindung von immunglobulinen
EA200700973A1 (ru) Слитый белок, содержащий домен bh3 белка «вh3-только»
DK0724637T3 (da) Kortikotropinfrigørende faktor2-receptorer
DK0434605T3 (da) Ny fremgangsmåde til fremstilling af ikke-fusioneret protein i E.coli
DE60330489D1 (de) Schnell abgebaute reporter-fusionsproteine
ATE435277T1 (de) 18477, eine menschliche proteinkinase und deren verwendung
CY1116756T1 (el) Αιμοκυανινη και κωδικευουσα γι'αυτην ακολουθια νουκλεϊνικου οξεος
DK1012256T3 (da) Rekombinante fusionsproteiner på basis af ribosom-inaktiverende proteiner fra misteltenen Viscum album
DE69813476D1 (de) G-protein-gekoppelter rezeptor mit selektiver affinität für atp