DK0971946T3 - Selektion af proteiner ved anvendelse af RNA-protein-fusioner - Google Patents

Selektion af proteiner ved anvendelse af RNA-protein-fusioner

Info

Publication number
DK0971946T3
DK0971946T3 DK98904574T DK98904574T DK0971946T3 DK 0971946 T3 DK0971946 T3 DK 0971946T3 DK 98904574 T DK98904574 T DK 98904574T DK 98904574 T DK98904574 T DK 98904574T DK 0971946 T3 DK0971946 T3 DK 0971946T3
Authority
DK
Denmark
Prior art keywords
rna
selection
proteins
protein fusions
protein
Prior art date
Application number
DK98904574T
Other languages
English (en)
Inventor
Richard W Roberts
Jack W Szostak
Rihe Liu
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26712662&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0971946(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of DK0971946T3 publication Critical patent/DK0971946T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1062—Isolating an individual clone by screening libraries mRNA-Display, e.g. polypeptide and encoding template are connected covalently
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1048—SELEX
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK98904574T 1997-01-21 1998-01-14 Selektion af proteiner ved anvendelse af RNA-protein-fusioner DK0971946T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3596397P 1997-01-21 1997-01-21
US6449197P 1997-11-06 1997-11-06

Publications (1)

Publication Number Publication Date
DK0971946T3 true DK0971946T3 (da) 2006-10-30

Family

ID=26712662

Family Applications (2)

Application Number Title Priority Date Filing Date
DK98904574T DK0971946T3 (da) 1997-01-21 1998-01-14 Selektion af proteiner ved anvendelse af RNA-protein-fusioner
DK06013825.2T DK1712623T3 (da) 1997-01-21 1998-01-14 Udvælgelse af proteiner ved anvendelse af RNA-proteinfusioner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK06013825.2T DK1712623T3 (da) 1997-01-21 1998-01-14 Udvælgelse af proteiner ved anvendelse af RNA-proteinfusioner

Country Status (16)

Country Link
US (5) US6258558B1 (da)
EP (2) EP1712623B1 (da)
JP (1) JP3692542B2 (da)
KR (1) KR100566859B1 (da)
CN (1) CN1238366C (da)
AT (2) ATE529509T1 (da)
AU (1) AU738328B2 (da)
CA (1) CA2278786C (da)
DE (1) DE69835143T2 (da)
DK (2) DK0971946T3 (da)
ES (2) ES2268763T3 (da)
IL (1) IL131016A (da)
PT (2) PT1712623E (da)
RU (1) RU2233878C2 (da)
TW (1) TW589323B (da)
WO (1) WO1998031700A1 (da)

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CN1251593A (zh) 2000-04-26
US6518018B1 (en) 2003-02-11
WO1998031700A1 (en) 1998-07-23
EP0971946A1 (en) 2000-01-19
KR100566859B1 (ko) 2006-04-03
ES2373110T3 (es) 2012-01-31
AU738328B2 (en) 2001-09-13
DK1712623T3 (da) 2012-02-06
ES2268763T3 (es) 2007-03-16
ATE529509T1 (de) 2011-11-15
ATE332368T1 (de) 2006-07-15
DE69835143D1 (de) 2006-08-17
US6214553B1 (en) 2001-04-10
DE69835143T2 (de) 2007-06-06
CA2278786A1 (en) 1998-07-23
IL131016A (en) 2004-12-15
EP1712623B1 (en) 2011-10-19
US6207446B1 (en) 2001-03-27
AU6241998A (en) 1998-08-07
KR20000070361A (ko) 2000-11-25
JP2002513281A (ja) 2002-05-08
US6258558B1 (en) 2001-07-10
CN1238366C (zh) 2006-01-25
PT971946E (pt) 2006-11-30
JP3692542B2 (ja) 2005-09-07
IL131016A0 (en) 2001-01-28
TW589323B (en) 2004-06-01
EP0971946A4 (en) 2002-12-04
EP0971946B1 (en) 2006-07-05
EP1712623A3 (en) 2008-10-15
EP1712623A2 (en) 2006-10-18
CA2278786C (en) 2010-07-20
HK1027577A1 (en) 2001-01-19
US6281344B1 (en) 2001-08-28
RU2233878C2 (ru) 2004-08-10
PT1712623E (pt) 2011-12-21

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