DK0973780T3 - Antibakterielle substituerede 7-acylamino-3-(methylhydrazono)-methylcephalosporiner og mellemprodukter - Google Patents

Antibakterielle substituerede 7-acylamino-3-(methylhydrazono)-methylcephalosporiner og mellemprodukter

Info

Publication number
DK0973780T3
DK0973780T3 DK98922631T DK98922631T DK0973780T3 DK 0973780 T3 DK0973780 T3 DK 0973780T3 DK 98922631 T DK98922631 T DK 98922631T DK 98922631 T DK98922631 T DK 98922631T DK 0973780 T3 DK0973780 T3 DK 0973780T3
Authority
DK
Denmark
Prior art keywords
methylcephalosporins
methylhydrazono
acylamino
intermediates
antibacterial
Prior art date
Application number
DK98922631T
Other languages
English (en)
Inventor
Gerd Ascher
Josef Wieser
Michael Schranz
Johannes Ludescher
Johannes Hildebrandt
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT54797A external-priority patent/AT405180B/de
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Application granted granted Critical
Publication of DK0973780T3 publication Critical patent/DK0973780T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK98922631T 1997-04-01 1998-04-01 Antibakterielle substituerede 7-acylamino-3-(methylhydrazono)-methylcephalosporiner og mellemprodukter DK0973780T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AT54697 1997-04-01
AT54797A AT405180B (de) 1997-04-01 1997-04-01 Neue derivate von substituierten 3-cephem-4-carbonsäurederivaten und verfahren zu deren herstellung
AT54897 1997-04-01
PCT/EP1998/001890 WO1998043981A1 (en) 1997-04-01 1998-04-01 Antibacterial substituted 7-acylamino-3-(methylhydrazono)methyl -cephalosporins and intermediates

Publications (1)

Publication Number Publication Date
DK0973780T3 true DK0973780T3 (da) 2003-10-27

Family

ID=27146440

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98922631T DK0973780T3 (da) 1997-04-01 1998-04-01 Antibakterielle substituerede 7-acylamino-3-(methylhydrazono)-methylcephalosporiner og mellemprodukter

Country Status (20)

Country Link
EP (2) EP1300408A1 (da)
JP (2) JP3363157B2 (da)
KR (2) KR20040000380A (da)
CN (1) CN1117095C (da)
AU (1) AU734897B2 (da)
BR (1) BR9807913A (da)
CA (1) CA2284501C (da)
DE (1) DE69816057T2 (da)
DK (1) DK0973780T3 (da)
ES (1) ES2203955T3 (da)
ID (1) ID22441A (da)
IL (1) IL131849A (da)
NO (1) NO325687B1 (da)
NZ (1) NZ337732A (da)
PL (1) PL200130B1 (da)
PT (1) PT973780E (da)
RU (1) RU2201933C2 (da)
SK (1) SK133099A3 (da)
TR (1) TR199902387T2 (da)
WO (1) WO1998043981A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT406772B (de) * 1998-03-23 2000-08-25 Biochemie Gmbh Antibakterielle 7-acylamino-3-iminomethyl- cephalosporine und verfahren zu deren herstellung
US6504025B2 (en) * 2000-05-24 2003-01-07 Basilea Pharmaceutica Ag Process for the preparation of vinyl-pyrrolidinone cephalosporin derivatives
AT413282B (de) * 2002-02-01 2006-01-15 Sandoz Ag Kristalline salze der 7-(((5-amino-1,2,4-thiadiazol-3-yl) (fluoromethoxy-imino)acetyl)amino)-3- ((imino-1-piperazinylmethyl)
KR20220061163A (ko) 2019-09-06 2022-05-12 나브리바 테라퓨틱스 게엠베하 사이드로포어 세팔로스포린 접합체 및 이의 용도
CN111187281B (zh) * 2020-02-11 2023-03-14 广西科技大学 含胍基的头孢菌素衍生物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU190639B (en) * 1983-12-12 1986-09-29 Gyogyszerkutato Intezet Kv,Hu Process for production of new aminoguanidin derivatives
FI851934L (fi) * 1984-05-30 1985-12-01 Ici Plc Kefalosporinderivat.
RU2010796C1 (ru) * 1986-10-13 1994-04-15 Эйсай Ко., ЛТД Способ получения производных 3-пропенилцефема или их фармакологически приемлемых солей
ATE233268T1 (de) * 1995-05-11 2003-03-15 Biochemie Gmbh Antibakterielle cephalosporinverbindungen

Also Published As

Publication number Publication date
NO994719L (no) 1999-09-28
EP0973780B1 (en) 2003-07-02
DE69816057D1 (de) 2003-08-07
JP2000514832A (ja) 2000-11-07
NZ337732A (en) 2001-09-28
JP2002316992A (ja) 2002-10-31
WO1998043981A1 (en) 1998-10-08
NO325687B1 (no) 2008-07-07
DE69816057T2 (de) 2004-04-15
NO994719D0 (no) 1999-09-28
CA2284501A1 (en) 1998-10-08
JP3363157B2 (ja) 2003-01-08
KR100481143B1 (ko) 2005-04-08
BR9807913A (pt) 2000-02-22
CN1251591A (zh) 2000-04-26
EP0973780A1 (en) 2000-01-26
KR20000076288A (ko) 2000-12-26
PL200130B1 (pl) 2008-12-31
SK133099A3 (en) 2001-03-12
PT973780E (pt) 2003-11-28
CA2284501C (en) 2007-07-17
RU2201933C2 (ru) 2003-04-10
AU7521398A (en) 1998-10-22
TR199902387T2 (xx) 2000-01-21
EP1300408A1 (en) 2003-04-09
KR20040000380A (ko) 2004-01-03
ES2203955T3 (es) 2004-04-16
AU734897B2 (en) 2001-06-28
CN1117095C (zh) 2003-08-06
IL131849A0 (en) 2001-03-19
ID22441A (id) 1999-10-14
PL336004A1 (en) 2000-06-05
HK1026692A1 (en) 2000-12-22
IL131849A (en) 2004-05-12

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