DK0973790T3 - Estra-5(10),7-diener med østrogen aktivitet - Google Patents

Estra-5(10),7-diener med østrogen aktivitet

Info

Publication number
DK0973790T3
DK0973790T3 DK98915224T DK98915224T DK0973790T3 DK 0973790 T3 DK0973790 T3 DK 0973790T3 DK 98915224 T DK98915224 T DK 98915224T DK 98915224 T DK98915224 T DK 98915224T DK 0973790 T3 DK0973790 T3 DK 0973790T3
Authority
DK
Denmark
Prior art keywords
estra
dienes
estrogenic activity
estrogenic
activity
Prior art date
Application number
DK98915224T
Other languages
English (en)
Inventor
Leonard Alexander Mcdonald
Michael Z Kagan
Syed Muzafar Shah
Panolil Raveendranath
Mark Andrew Collins
Fangming Kong
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK0973790T3 publication Critical patent/DK0973790T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005—Glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98915224T 1997-04-07 1998-04-02 Estra-5(10),7-diener med østrogen aktivitet DK0973790T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83533697A 1997-04-07 1997-04-07
US85057097A 1997-05-02 1997-05-02
PCT/US1998/006461 WO1998045315A1 (en) 1997-04-07 1998-04-02 Estra-5(10),7-dienes with estrogenic activity

Publications (1)

Publication Number Publication Date
DK0973790T3 true DK0973790T3 (da) 2003-09-22

Family

ID=27125779

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98915224T DK0973790T3 (da) 1997-04-07 1998-04-02 Estra-5(10),7-diener med østrogen aktivitet

Country Status (15)

Country Link
EP (1) EP0973790B1 (da)
JP (1) JP2001518896A (da)
KR (1) KR20010006118A (da)
CN (1) CN1259137A (da)
AR (1) AR012341A1 (da)
AT (1) ATE242263T1 (da)
AU (1) AU738486B2 (da)
BR (1) BR9809748A (da)
CA (1) CA2286457A1 (da)
DE (1) DE69815329T2 (da)
DK (1) DK0973790T3 (da)
ES (1) ES2200334T3 (da)
NZ (1) NZ500217A (da)
PT (1) PT973790E (da)
WO (1) WO1998045315A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1368037A2 (en) * 2001-03-16 2003-12-10 Wyeth Estrogen replacement therapy
EP2268655A4 (en) * 2008-03-24 2013-03-13 Signa Chemistry Llc BIRCH REDUCTION OF STEROIDSUBSTRATES ON ALKALIMETAL SILICA GEL MATERIALS
KR20150036319A (ko) 2012-07-10 2015-04-07 바이엘 파마 악티엔게젤샤프트 3-치환된 에스트라-1,3,5(10),16-테트라엔 유도체, 그의 제조방법, 이를 포함하는 약학 제제 및 의약품 제조를 위한 그의 용도
MX2015010876A (es) 2013-02-21 2015-12-03 Bayer Pharma AG Estra-1,3,5(10),16-tetraeno-3-carboxamidas para la inhibicion de la 17b-hidroxiesteroide deshidrogenasa (akr1 c3).

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2930805A (en) * 1959-01-19 1960-03-29 American Home Prod Novel derivatives of estrane
DE1093360B (de) * 1958-02-17 1960-11-24 Ayerst Mckenna & Harrison Verfahren zur Herstellung von stabilen antioestrogen wirksamen Verbindungen der Oestranreihe
US3340278A (en) * 1965-05-03 1967-09-05 American Home Prod 5(10), 7-estradiene-3, 17-dione and the process for the production thereof
EP0565296B1 (en) * 1992-04-07 1996-08-07 Neurim Pharmaceuticals (1991) Limited Use of melatonin for the manufacture of a medicament for the treatment of benign prostatic hyperplasia

Also Published As

Publication number Publication date
PT973790E (pt) 2003-10-31
EP0973790A1 (en) 2000-01-26
BR9809748A (pt) 2000-06-20
CN1259137A (zh) 2000-07-05
JP2001518896A (ja) 2001-10-16
WO1998045315A1 (en) 1998-10-15
DE69815329D1 (de) 2003-07-10
NZ500217A (en) 2001-11-30
EP0973790B1 (en) 2003-06-04
KR20010006118A (ko) 2001-01-26
AU738486B2 (en) 2001-09-20
DE69815329T2 (de) 2004-04-29
ES2200334T3 (es) 2004-03-01
CA2286457A1 (en) 1998-10-15
ATE242263T1 (de) 2003-06-15
AR012341A1 (es) 2000-10-18
AU6946298A (en) 1998-10-30

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