DK0975775T3 - Regulatorisk system til inducerbar ekspression af gener med lambdapromotorer - Google Patents
Regulatorisk system til inducerbar ekspression af gener med lambdapromotorerInfo
- Publication number
- DK0975775T3 DK0975775T3 DK98924212T DK98924212T DK0975775T3 DK 0975775 T3 DK0975775 T3 DK 0975775T3 DK 98924212 T DK98924212 T DK 98924212T DK 98924212 T DK98924212 T DK 98924212T DK 0975775 T3 DK0975775 T3 DK 0975775T3
- Authority
- DK
- Denmark
- Prior art keywords
- antirepressor
- promoter
- gene coding
- genes
- gene
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 9
- 230000001939 inductive effect Effects 0.000 title abstract 4
- 230000001105 regulatory effect Effects 0.000 title abstract 3
- 101710197208 Regulatory protein cro Proteins 0.000 abstract 5
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/73—Expression systems using phage (lambda) regulatory sequences
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10311—Siphoviridae
- C12N2795/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Mushroom Cultivation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1005884 | 1997-04-23 | ||
| PCT/EP1998/002465 WO1998048025A2 (fr) | 1997-04-23 | 1998-04-23 | Systeme regulateur destine a l'expression induite de genes au moyen de promoteurs lambdoides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0975775T3 true DK0975775T3 (da) | 2004-07-26 |
Family
ID=19764839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98924212T DK0975775T3 (da) | 1997-04-23 | 1998-04-23 | Regulatorisk system til inducerbar ekspression af gener med lambdapromotorer |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6485934B1 (fr) |
| EP (1) | EP0975775B1 (fr) |
| JP (1) | JP2001526533A (fr) |
| AT (1) | ATE262041T1 (fr) |
| AU (1) | AU729712B2 (fr) |
| CA (1) | CA2287541C (fr) |
| DE (1) | DE69822453T2 (fr) |
| DK (1) | DK0975775T3 (fr) |
| PT (1) | PT975775E (fr) |
| WO (1) | WO1998048025A2 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ541551A (en) * | 2003-02-21 | 2007-02-23 | Biotecnol Sa | Use of caspase enzymes for maturation of engineered recombinant polypeptide fusions |
| WO2008120107A2 (fr) | 2007-04-03 | 2008-10-09 | Oxyrane (Uk) Limited | Glycosylation de molécules |
| US9598682B2 (en) | 2009-09-29 | 2017-03-21 | Vib Vzw | Hydrolysis of mannose-1-phospho-6-mannose linkage to phospho-6-mannose |
| US20130053550A1 (en) | 2009-11-19 | 2013-02-28 | Oxyrane Uk Limited | Yeast strains producing mammalian-like complex n-glycans |
| US9347050B2 (en) | 2010-09-29 | 2016-05-24 | Oxyrane Uk Limited | Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated N-glycans and methods of facilitating mammalian cellular uptake of glycoproteins |
| WO2012042387A2 (fr) | 2010-09-29 | 2012-04-05 | Oxyrane Uk Limited | Démannosylation des n-glycanes phosphorylés |
| WO2012170433A1 (fr) * | 2011-06-08 | 2012-12-13 | Sutro Biopharma, Inc. | Cassettes de terminaison des multiples arn polymérases pour une transcription efficace d'échantillons d'arn discrets |
| EP3628326B1 (fr) | 2012-03-15 | 2024-02-28 | Oxyrane UK Limited | Méthodes et substances permettant de traiter la maladie de pompe |
| CN112521472B (zh) * | 2020-12-04 | 2023-02-07 | 海南波莲水稻基因科技有限公司 | 一种与水稻育性及花器官数目相关的分子标记及其应用 |
| GB202205833D0 (en) * | 2022-04-21 | 2022-06-08 | Glaxosmithkline Biologicals Sa | Bacteriophage |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3319242A1 (de) * | 1983-05-27 | 1984-11-29 | Battelle-Institut E.V., 6000 Frankfurt | Verfahren und plasmid zur steuerung der expression von klonierten genen |
| US5571786A (en) | 1990-08-16 | 1996-11-05 | Immuno Aktiengesellschaft | Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation |
| US5416008A (en) * | 1991-10-01 | 1995-05-16 | California Institute Of Technology | Cross-regulation of gene expression in recombinant cells |
-
1998
- 1998-04-23 AT AT98924212T patent/ATE262041T1/de active
- 1998-04-23 AU AU76491/98A patent/AU729712B2/en not_active Ceased
- 1998-04-23 JP JP54504898A patent/JP2001526533A/ja active Pending
- 1998-04-23 CA CA2287541A patent/CA2287541C/fr not_active Expired - Fee Related
- 1998-04-23 PT PT98924212T patent/PT975775E/pt unknown
- 1998-04-23 US US09/403,651 patent/US6485934B1/en not_active Expired - Fee Related
- 1998-04-23 DE DE69822453T patent/DE69822453T2/de not_active Expired - Lifetime
- 1998-04-23 WO PCT/EP1998/002465 patent/WO1998048025A2/fr not_active Ceased
- 1998-04-23 DK DK98924212T patent/DK0975775T3/da active
- 1998-04-23 EP EP98924212A patent/EP0975775B1/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001526533A (ja) | 2001-12-18 |
| WO1998048025A3 (fr) | 1999-01-21 |
| DE69822453D1 (de) | 2004-04-22 |
| US6485934B1 (en) | 2002-11-26 |
| CA2287541C (fr) | 2010-04-20 |
| CA2287541A1 (fr) | 1998-10-29 |
| WO1998048025A2 (fr) | 1998-10-29 |
| ATE262041T1 (de) | 2004-04-15 |
| EP0975775A2 (fr) | 2000-02-02 |
| AU7649198A (en) | 1998-11-13 |
| DE69822453T2 (de) | 2005-03-24 |
| PT975775E (pt) | 2004-07-30 |
| AU729712B2 (en) | 2001-02-08 |
| EP0975775B1 (fr) | 2004-03-17 |
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