DK0983272T3 - En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater - Google Patents

En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater

Info

Publication number: DK0983272T3
Authority: DK; Denmark
Prior art keywords: new class; compounds consisting; photoactive compounds; benzoporphyrin derivatives; benzoporphyrin
Prior art date: 1997-05-07

Application number

DK98916765T

Other languages

English (en)

Inventor

Ethan Sternberg

David Dolphin

Julia G Levy

Anna M Richter

Andrew Tovey

Original Assignee

Univ British Columbia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-07

Filing date

1998-04-29

Publication date

2004-03-01

1997-08-26 Priority claimed from US08/918,840 external-priority patent/US5880145A/en

1998-04-29 Application filed by Univ British Columbia filed Critical Univ British Columbia

2004-03-01 Application granted granted Critical

2004-03-01 Publication of DK0983272T3 publication Critical patent/DK0983272T3/da

Links

150000001875 compounds Chemical class 0.000 title abstract 3
MHIITNFQDPFSES-UHFFFAOYSA-N 25,26,27,28-tetrazahexacyclo[16.6.1.13,6.18,11.113,16.019,24]octacosa-1(25),2,4,6,8(27),9,11,13,15,17,19,21,23-tridecaene Chemical class N1C(C=C2C3=CC=CC=C3C(C=C3NC(=C4)C=C3)=N2)=CC=C1C=C1C=CC4=N1 MHIITNFQDPFSES-UHFFFAOYSA-N 0.000 title 1
PLVAJLBZYYGQNL-UHFFFAOYSA-N C12CC=C(N1)C=C1C=CC(=N1)C=C1C=CC(N1)=CC=1C3=C(C(N=1)=C2)C=CC=C3 Chemical class C12CC=C(N1)C=C1C=CC(=N1)C=C1C=CC(N1)=CC=1C3=C(C(N=1)=C2)C=CC=C3 PLVAJLBZYYGQNL-UHFFFAOYSA-N 0.000 abstract 1
150000001298 alcohols Chemical class 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
238000002428 photodynamic therapy Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK98916765T 1997-05-07 1998-04-29 En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater DK0983272T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US85232697A	1997-05-07	1997-05-07
US08/918,840 US5880145A (en)	1997-05-07	1997-08-26	Class of benzoporphyrin derivative photoactive compounds
PCT/CA1998/000425 WO1998050386A1 (en)	1997-05-07	1998-04-29	A new class of benzoporphyrin derivative photoactive compounds

Publications (1)

Publication Number	Publication Date
DK0983272T3 true DK0983272T3 (da)	2004-03-01

Family

ID=27127060

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98916765T DK0983272T3 (da)	1997-05-07	1998-04-29	En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater

Country Status (18)

Country	Link
US (1)	US5990149A (da)
EP (1)	EP0983272B1 (da)
JP (2)	JP3907212B2 (da)
CN (1)	CN1120166C (da)
AT (1)	ATE253068T1 (da)
AU (1)	AU749741B2 (da)
CA (1)	CA2288045C (da)
CZ (1)	CZ299361B6 (da)
DE (1)	DE69819318T2 (da)
DK (1)	DK0983272T3 (da)
ES (1)	ES2210740T3 (da)
HU (1)	HU224176B1 (da)
IL (1)	IL132494A0 (da)
NO (1)	NO314806B1 (da)
PL (1)	PL202340B1 (da)
PT (1)	PT983272E (da)
TW (1)	TW474938B (da)
WO (1)	WO1998050386A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT983273E (pt) *	1997-05-07	2002-06-28	Quadra Logic Tech Inc	Esteres etilenoglicolicos de derivados de mono-hidrobenzoporfirina como agentes fotoactivos
US6756396B1 (en)	1997-05-07	2004-06-29	Qlt Inc.	Ethylene glycol esters as photoactive agents
AU4278400A (en) *	1999-04-14	2000-11-14	University Of British Columbia, The	Improved beta,beta,-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US20020022032A1 (en) *	1999-04-23	2002-02-21	Curry Patrick Mark	Immuno-adjuvant PDT treatment of metastatic tumors
US7122568B1 (en)	1999-11-17	2006-10-17	Qlt, Inc.	Use of low-dose PDT to inhibit restenosis
US6984395B2 (en) *	2001-04-11	2006-01-10	Qlt, Inc.	Drug delivery system for hydrophobic drugs
DE60225844T2 (de) *	2001-11-02	2009-04-09	The Governors Of The University Of Alberta, Edmonton	Micelle-zusammensetzungen enthaltend pegylierten phospholipide und einen photosensibilisator
EP1441767A1 (en) *	2001-11-09	2004-08-04	QLT Inc.	Compositions comprising a photosensitizer and a skin-penetration enhancer and their use in photodynamic treatment
CA2437638A1 (en) *	2003-08-20	2005-02-20	John Robert North	Photodynamic therapy
CA2457214A1 (en)	2004-02-06	2005-08-06	Qlt Inc.	Photodynamic therapy for the treatment of acne
GB0415663D0 (en) *	2004-07-13	2004-08-18	Psimei Pharmaceuticals Plc	Compound
FR2877943B1 (fr)	2004-11-16	2008-09-05	Univ De Coimbra	Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
KR20140089478A (ko)	2011-01-13	2014-07-15	큐엘티 인코포레이티드	감광제의 국소 전달용 약학 조성물 및 그의 이용
MX2015000429A (es)	2012-07-11	2015-07-14	Dermira Inc	Composiciones farmaceuticas para el suministro topico de fotosesibilizadores y usos de los mismos.
AU2024251073A1 (en) *	2023-04-14	2025-10-23	Nira Biosciences, Inc.	Benzoporphyrin analogs, conjugates, and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4883790A (en) *	1987-01-20	1989-11-28	University Of British Columbia	Wavelength-specific cytotoxic agents
US4920143A (en) *	1987-04-23	1990-04-24	University Of British Columbia	Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents
US5880145A (en) *	1997-05-07	1999-03-09	The University Of British Columbia	Class of benzoporphyrin derivative photoactive compounds

1998
- 1998-04-29 PT PT98916765T patent/PT983272E/pt unknown
- 1998-04-29 JP JP54757098A patent/JP3907212B2/ja not_active Expired - Fee Related
- 1998-04-29 IL IL13249498A patent/IL132494A0/xx active IP Right Grant
- 1998-04-29 CN CN98804869A patent/CN1120166C/zh not_active Expired - Fee Related
- 1998-04-29 HU HU0003939A patent/HU224176B1/hu not_active IP Right Cessation
- 1998-04-29 AT AT98916765T patent/ATE253068T1/de not_active IP Right Cessation
- 1998-04-29 PL PL336633A patent/PL202340B1/pl not_active IP Right Cessation
- 1998-04-29 EP EP98916765A patent/EP0983272B1/en not_active Expired - Lifetime
- 1998-04-29 CA CA002288045A patent/CA2288045C/en not_active Expired - Fee Related
- 1998-04-29 WO PCT/CA1998/000425 patent/WO1998050386A1/en not_active Ceased
- 1998-04-29 DE DE69819318T patent/DE69819318T2/de not_active Expired - Fee Related
- 1998-04-29 CZ CZ0385799A patent/CZ299361B6/cs not_active IP Right Cessation
- 1998-04-29 ES ES98916765T patent/ES2210740T3/es not_active Expired - Lifetime
- 1998-04-29 DK DK98916765T patent/DK0983272T3/da active
- 1998-04-29 AU AU70257/98A patent/AU749741B2/en not_active Ceased
- 1998-07-21 TW TW087111990A patent/TW474938B/zh not_active IP Right Cessation
1999
- 1999-03-09 US US09/265,245 patent/US5990149A/en not_active Expired - Fee Related
- 1999-11-05 NO NO19995440A patent/NO314806B1/no not_active IP Right Cessation
2004
- 2004-03-24 JP JP2004088106A patent/JP2004217671A/ja active Pending

Also Published As

Publication number	Publication date
CA2288045A1 (en)	1998-11-12
CN1120166C (zh)	2003-09-03
TW474938B (en)	2002-02-01
HUP0003939A3 (en)	2003-06-30
NO314806B1 (no)	2003-05-26
ES2210740T3 (es)	2004-07-01
AU749741B2 (en)	2002-07-04
EP0983272A1 (en)	2000-03-08
JP2000516636A (ja)	2000-12-12
IL132494A0 (en)	2001-03-19
ATE253068T1 (de)	2003-11-15
DE69819318D1 (de)	2003-12-04
CZ385799A3 (cs)	2000-04-12
US5990149A (en)	1999-11-23
WO1998050386A1 (en)	1998-11-12
CZ299361B6 (cs)	2008-07-02
JP2004217671A (ja)	2004-08-05
CN1255135A (zh)	2000-05-31
DE69819318T2 (de)	2004-08-19
HK1025324A1 (en)	2000-11-10
CA2288045C (en)	2007-01-23
PL336633A1 (en)	2000-07-03
AU7025798A (en)	1998-11-27
NO995440L (no)	1999-11-05
HU224176B1 (hu)	2005-06-28
JP3907212B2 (ja)	2007-04-18
HUP0003939A2 (en)	2001-03-28
NO995440D0 (no)	1999-11-05
PL202340B1 (pl)	2009-06-30
EP0983272B1 (en)	2003-10-29
PT983272E (pt)	2004-03-31

Publication	Publication Date	Title
DK0983272T3 (da)	2004-03-01	En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater
EP1380586A3 (en)	2004-02-11	Photoactive benzoporphyrin derivatives
DE60010098D1 (de)	2004-05-27	28-epirapaloge
DE69434281D1 (de)	2005-04-07	Stromversorgung
DE69402126D1 (de)	1997-04-24	Anthracenderivate
DE69330075D1 (de)	2001-05-10	Oxazolinderivate, ihre Herstellung und Anwendung
DE60119813D1 (de)	2006-06-29	Raupe und dessen Herstellungsverfahren
FI970449A7 (fi)	1997-04-03	N-substituoituja atsabisykloheptaanijohdannaisia, jotka ovat käyttökel poisia neuroleptisinä aineina
EE03615B1 (et)	2002-02-15	Pürasool-4-üülhetaroüülderivaadid herbitsiididena
FI940568A7 (fi)	1994-08-10	Anti-inflammatorisina aineina toimivia oksindoli-1-(N-(alkoksikarbonyyli))karboksamideja ja -1-(N-karboksamido)-karboksamideja
NO960636L (no)	1996-04-16	Kraft-forsterker
FI933675L (fi)	1995-02-21	Parannettu virtalähde
TR25943A (tr)	1993-11-01	DISAZOBILESIKLERI, BUNLARIN üRETILMELERINE MAHSUS USUL VE BOYAR MADDE OLARAK KULLANILMALARI
KR980000268U (ko)	1998-03-30	선글라스가 부설된 모자
KR950031717U (ko)	1995-11-22	휴대용 이어폰케이스
DE69328554D1 (de)	2000-06-08	Diguanamine, herstellung, derivate und anwendung
KR950004689U (ko)	1995-02-18	꽂음플럭용 캡타이어 전원코드
KR940025734U (ko)	1994-11-18	머리띠 겸용 무선이어폰
KR940026509U (ko)	1994-12-08	장신구가 내장된 양초
NO972805L (no)	1998-12-18	Strekkopptagende anordning
DK63593A (da)	1994-12-04	Ny energiform
FI932776A7 (fi)	1994-12-17	Pohjaan kiinnitettävä paalu
DK66993D0 (da)	1993-06-08	Braendeflaekker
DK71393D0 (da)	1993-06-16	Oeresmykke
KR950016032U (ko)	1995-06-19	스피커 고정장치