DK0988312T3 - 17beta-allyloxy(thio)alkyl-androstanderivater til modulering af meiose - Google Patents

17beta-allyloxy(thio)alkyl-androstanderivater til modulering af meiose

Info

Publication number: DK0988312T3
Authority: DK; Denmark
Prior art keywords: alkyl; 17beta; allyloxy; thio; independently hydrogen
Prior art date: 1997-06-04

Application number

DK98936293T

Other languages

English (en)

Inventor

Johannes Antonius Jos Leemhuis

Der Louw Jaap Van

Marinus Bernard Groen

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-04

Filing date

1998-05-28

Publication date

2002-07-15

1998-05-28 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2002-07-15 Application granted granted Critical

2002-07-15 Publication of DK0988312T3 publication Critical patent/DK0988312T3/da

Links

230000021121 meiosis Effects 0.000 title abstract 2
-1 alkyl androstane derivatives Chemical class 0.000 title 1
125000000446 sulfanediyl group Chemical group *S* 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
229910020008 S(O) Inorganic materials 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
229910004727 OSO3H Inorganic materials 0.000 abstract 1
230000003213 activating effect Effects 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
150000001721 carbon Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
230000035558 fertility Effects 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
- C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK98936293T 1997-06-04 1998-05-28 17beta-allyloxy(thio)alkyl-androstanderivater til modulering af meiose DK0988312T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97201691		1997-06-04
PCT/EP1998/003191 WO1998055498A1 (en)	1997-06-04	1998-05-28	17β-ALLYLOXY(THIO)ALKYL-ANDROSTANE DERIVATIVES FOR THE MODULATION OF MEIOSIS

Publications (1)

Publication Number	Publication Date
DK0988312T3 true DK0988312T3 (da)	2002-07-15

Family

ID=8228406

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98936293T DK0988312T3 (da)	1997-06-04	1998-05-28	17beta-allyloxy(thio)alkyl-androstanderivater til modulering af meiose

Country Status (16)

Country	Link
US (1)	US6262282B1 (da)
EP (1)	EP0988312B1 (da)
JP (1)	JP2002502404A (da)
KR (1)	KR20010013401A (da)
CN (1)	CN1259138A (da)
AT (1)	ATE215555T1 (da)
AU (1)	AU8535398A (da)
CA (1)	CA2289524A1 (da)
DE (1)	DE69804611T2 (da)
DK (1)	DK0988312T3 (da)
HU (1)	HUP0002904A2 (da)
IL (1)	IL132799A0 (da)
NO (1)	NO995935L (da)
PL (1)	PL337188A1 (da)
TR (1)	TR199902873T2 (da)
WO (1)	WO1998055498A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2181321T3 (es) *	1997-12-18	2003-02-16	Akzo Nobel Nv	Derivados 17beta-aril(arilmetil)oxi(tio)alquilandrostano.
DE69913513T2 (de) *	1998-05-13	2004-09-30	Novo Nordisk A/S	Verwendung von verbindungen mit der fähigkeit die meiose zu regulieren
AU4498299A (en) *	1998-06-19	2000-01-10	Novo Nordisk A/S	Meiosis regulating compounds
CN1353617A (zh) *	1999-02-24	2002-06-12	诺沃挪第克公司	不孕症的治疗
EP1156821B1 (en) *	1999-02-24	2007-05-02	Novo Nordisk A/S	Treatment of infertility
JP2002538123A (ja) *	1999-03-02	2002-11-12	アクゾ・ノベル・エヌ・ベー	（アンドロスト−５−エン−１７β−イル）アルキルスルホキシドおよびスルホンならびに受胎能の調節のためのその使用
US6756366B1 (en) *	1999-04-06	2004-06-29	Akzo Nobel N.V.	Orally active androgens
DE60023324T2 (de)	1999-09-16	2006-07-20	Novo Nordisk A/S	Zusammensetzung zur in-vitro befruchtung
EP1127890A1 (en)	2000-02-22	2001-08-29	Schering Aktiengesellschaft	Steroid derivatives with an additional ring annulated to ring A and use of these derivatives for the preparation of meiosis regulating medicaments
AU3376501A (en) *	2000-02-25	2001-09-03	Novo Nordisk A/S	Improvement of implantation rate
CA2404822A1 (en) *	2000-05-18	2001-11-22	Novo Nordisk A/S	Fertilization of aged oocytes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5716777A (en) *	1994-06-23	1998-02-10	Novo Nordisk A/S	Regulation of meiosis using sterols
PL322106A1 (en) *	1995-03-06	1998-01-05	Novo Nordisk As	Meiosis stimulation
PL185622B1 (pl) *	1995-06-23	2003-06-30	Novo Nordisk As	Zastosowanie związku steroidowego i sposób regulacji mejozy w komórce rozrodczej ssaka

1998
- 1998-05-28 AU AU85353/98A patent/AU8535398A/en not_active Abandoned
- 1998-05-28 CN CN98805807A patent/CN1259138A/zh active Pending
- 1998-05-28 DE DE69804611T patent/DE69804611T2/de not_active Expired - Fee Related
- 1998-05-28 PL PL98337188A patent/PL337188A1/xx unknown
- 1998-05-28 KR KR19997011402A patent/KR20010013401A/ko not_active Withdrawn
- 1998-05-28 IL IL13279998A patent/IL132799A0/xx unknown
- 1998-05-28 CA CA002289524A patent/CA2289524A1/en not_active Abandoned
- 1998-05-28 US US09/445,202 patent/US6262282B1/en not_active Expired - Fee Related
- 1998-05-28 EP EP98936293A patent/EP0988312B1/en not_active Expired - Lifetime
- 1998-05-28 JP JP50144599A patent/JP2002502404A/ja not_active Ceased
- 1998-05-28 WO PCT/EP1998/003191 patent/WO1998055498A1/en not_active Ceased
- 1998-05-28 TR TR1999/02873T patent/TR199902873T2/xx unknown
- 1998-05-28 DK DK98936293T patent/DK0988312T3/da active
- 1998-05-28 HU HU0002904A patent/HUP0002904A2/hu unknown
- 1998-05-28 AT AT98936293T patent/ATE215555T1/de not_active IP Right Cessation
1999
- 1999-12-03 NO NO995935A patent/NO995935L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CN1259138A (zh)	2000-07-05
DE69804611D1 (de)	2002-05-08
HUP0002904A2 (hu)	2001-02-28
JP2002502404A (ja)	2002-01-22
CA2289524A1 (en)	1998-12-10
NO995935D0 (no)	1999-12-03
EP0988312B1 (en)	2002-04-03
IL132799A0 (en)	2001-03-19
WO1998055498A1 (en)	1998-12-10
EP0988312A1 (en)	2000-03-29
TR199902873T2 (xx)	2000-04-21
DE69804611T2 (de)	2002-10-02
KR20010013401A (ko)	2001-02-26
US6262282B1 (en)	2001-07-17
AU8535398A (en)	1998-12-21
ATE215555T1 (de)	2002-04-15
PL337188A1 (en)	2000-08-14
NO995935L (no)	2000-02-03

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DK0870768T3 (da)	2002-07-01	Azaindol-ethylaminderivater som nikotinacetylcholinreceptor-bindingsmidler
YU34896A (sh)	1999-09-27	Supstituisani n-(indol-2-karbonil)-glicinamidi, njihovi intermedijeri i farmaceutske kompozicije
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ATE215555T1 (de)	2002-04-15	17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose
NO995590D0 (no)	1999-11-15	20-Aryl-5<alfa>-pregnan-derivater
TR199902350T2 (xx)	2000-04-21	Yeni piridin t�revleri ve onlardan olu�an farmakotik bile�imler.
NZ221699A (en)	1990-03-27	Pyridazinone derivatives; pharmaceutical compositions and intermediates
ATE79629T1 (de)	1992-09-15	17-substituierte androsta-1,4-dien-3-on-derivate.
DK1163258T3 (da)	2003-03-31	Derivater af 22R-hydroxycholesta-8, 14-dien til inhiberingen af meiosis
AU641686B2 (en)	1993-09-30	Benzanilides
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DK0565059T3 (da)	1996-10-14	Indolderivat
PT94906A (pt)	1991-04-18	Processo para a preparacao de novos derivados n-(23-vincristinoilicos) e n-(5'-noranidro-23-vinblastinoilicos) do acido 1-amino-metil-fosfonico
ES2115303T3 (es)	1998-06-16	Uso de compuestos de 5-tia-1,4-diazabiciclo(4.2.0)octan-3,8-dioxo en terapia antitumoral.
CO4920233A1 (es)	2000-05-29	Acidos aminobutiricos gamma substituidos como agentes farmaceuticos