ATE215555T1 - 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose - Google Patents

17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose

Info

Publication number: ATE215555T1
Authority: AT; Austria
Prior art keywords: alkyl; independently hydrogen; allyloxy; thio; meiosis
Prior art date: 1997-06-04

Application number

AT98936293T

Other languages

English (en)

Inventor

Johannes Antonius Jos Leemhuis

Der Louw Jaap Van

Marinus Bernard Groen

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-04

Filing date

1998-05-28

Publication date

2002-04-15

1998-05-28 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2002-04-15 Application granted granted Critical

2002-04-15 Publication of ATE215555T1 publication Critical patent/ATE215555T1/de

Links

230000021121 meiosis Effects 0.000 title abstract 2
SCVJRXQHFJXZFZ-KVQBGUIXSA-N 2-amino-9-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purine-6-thione Chemical class C1=2NC(N)=NC(=S)C=2N=CN1[C@H]1C[C@H](O)[C@@H](CO)O1 SCVJRXQHFJXZFZ-KVQBGUIXSA-N 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
229910020008 S(O) Inorganic materials 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
229910004727 OSO3H Inorganic materials 0.000 abstract 1
230000003213 activating effect Effects 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
150000001721 carbon Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
230000035558 fertility Effects 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
- C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT98936293T 1997-06-04 1998-05-28 17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose ATE215555T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97201691		1997-06-04
PCT/EP1998/003191 WO1998055498A1 (en)	1997-06-04	1998-05-28	17β-ALLYLOXY(THIO)ALKYL-ANDROSTANE DERIVATIVES FOR THE MODULATION OF MEIOSIS

Publications (1)

Publication Number	Publication Date
ATE215555T1 true ATE215555T1 (de)	2002-04-15

Family

ID=8228406

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98936293T ATE215555T1 (de)	1997-06-04	1998-05-28	17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose

Country Status (16)

Country	Link
US (1)	US6262282B1 (de)
EP (1)	EP0988312B1 (de)
JP (1)	JP2002502404A (de)
KR (1)	KR20010013401A (de)
CN (1)	CN1259138A (de)
AT (1)	ATE215555T1 (de)
AU (1)	AU8535398A (de)
CA (1)	CA2289524A1 (de)
DE (1)	DE69804611T2 (de)
DK (1)	DK0988312T3 (de)
HU (1)	HUP0002904A2 (de)
IL (1)	IL132799A0 (de)
NO (1)	NO995935L (de)
PL (1)	PL337188A1 (de)
TR (1)	TR199902873T2 (de)
WO (1)	WO1998055498A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2001526293A (ja) *	1997-12-18	2001-12-18	アクゾ・ノベル・エヌ・ベー	１７β−アリール（アリールメチル）オキシ（チオ）アルキル−アンドロスタン誘導体
WO1999058549A1 (en) *	1998-05-13	1999-11-18	Novo Nordisk A/S	Meiosis regulating compounds
IL140216A0 (en) *	1998-06-19	2002-02-10	Novo Nordisk As	Meiosis regulating compounds
CN1353617A (zh) *	1999-02-24	2002-06-12	诺沃挪第克公司	不孕症的治疗
AU2794000A (en)	1999-02-24	2000-09-14	Novo Nordisk A/S	Treatment of infertility
US6552011B1 (en)	1999-03-02	2003-04-22	Akzo Nobel Nv	(Androst-5-en-17beta -yl)alkyl sulfoxides and sulfones and their use for control of fertility
EP1212345B1 (de) *	1999-04-06	2003-08-06	Akzo Nobel N.V.	Oral wirksame 7-alpha-alkyl androgene
CA2382908A1 (en)	1999-09-16	2001-03-22	Novo Nordisk A/S	Composition for ivf
EP1127890A1 (de)	2000-02-22	2001-08-29	Schering Aktiengesellschaft	Steroid Derivate mit einem an Ring A des Steroidgerüstes kondensierten Ring zur Regulierung der Meiose
WO2001062260A2 (en) *	2000-02-25	2001-08-30	Schering Aktiengesellschaft	Improvement of implantation rate
MXPA02011271A (es) *	2000-05-18	2003-04-25	Schering Ag	Fertilizacion de oocitos envejecidos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5716777A (en) *	1994-06-23	1998-02-10	Novo Nordisk A/S	Regulation of meiosis using sterols
HUP9800731A3 (en) *	1995-03-06	2000-03-28	Novo Nordisk As	Stimulation of meiosis
CA2224866A1 (en) *	1995-06-23	1997-01-09	Novo Nordisk A/S	Meiosis regulating compounds

1998
- 1998-05-28 TR TR1999/02873T patent/TR199902873T2/xx unknown
- 1998-05-28 WO PCT/EP1998/003191 patent/WO1998055498A1/en not_active Ceased
- 1998-05-28 AT AT98936293T patent/ATE215555T1/de not_active IP Right Cessation
- 1998-05-28 CN CN98805807A patent/CN1259138A/zh active Pending
- 1998-05-28 CA CA002289524A patent/CA2289524A1/en not_active Abandoned
- 1998-05-28 HU HU0002904A patent/HUP0002904A2/hu unknown
- 1998-05-28 DE DE69804611T patent/DE69804611T2/de not_active Expired - Fee Related
- 1998-05-28 DK DK98936293T patent/DK0988312T3/da active
- 1998-05-28 PL PL98337188A patent/PL337188A1/xx unknown
- 1998-05-28 KR KR19997011402A patent/KR20010013401A/ko not_active Withdrawn
- 1998-05-28 EP EP98936293A patent/EP0988312B1/de not_active Expired - Lifetime
- 1998-05-28 US US09/445,202 patent/US6262282B1/en not_active Expired - Fee Related
- 1998-05-28 IL IL13279998A patent/IL132799A0/xx unknown
- 1998-05-28 AU AU85353/98A patent/AU8535398A/en not_active Abandoned
- 1998-05-28 JP JP50144599A patent/JP2002502404A/ja not_active Ceased
1999
- 1999-12-03 NO NO995935A patent/NO995935L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE69804611D1 (de)	2002-05-08
NO995935L (no)	2000-02-03
WO1998055498A1 (en)	1998-12-10
PL337188A1 (en)	2000-08-14
JP2002502404A (ja)	2002-01-22
KR20010013401A (ko)	2001-02-26
TR199902873T2 (xx)	2000-04-21
CN1259138A (zh)	2000-07-05
AU8535398A (en)	1998-12-21
DK0988312T3 (da)	2002-07-15
IL132799A0 (en)	2001-03-19
CA2289524A1 (en)	1998-12-10
EP0988312A1 (de)	2000-03-29
DE69804611T2 (de)	2002-10-02
NO995935D0 (no)	1999-12-03
HUP0002904A2 (hu)	2001-02-28
US6262282B1 (en)	2001-07-17
EP0988312B1 (de)	2002-04-03

Legal Events

Date	Code	Title	Description
2002-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DK0870768T3 (da)	2002-07-01	Azaindol-ethylaminderivater som nikotinacetylcholinreceptor-bindingsmidler
DE68914292D1 (de)	1994-05-11	Zusammensetzung zur Behandlung von ischämischen Störungen in Organen.
DE69728544D1 (de)	2004-05-13	Totalsynthese von acylfulvenen mit antitumorwirkung
ATE215555T1 (de)	2002-04-15	17-beta.-allyloxy(thio)alkyl-androstan derivative zur modulation von meiose
RU95105435A (ru)	1996-11-20	N-замещенные производные 3-азабицикло [3.2.0]гептана в качестве нейролептического средства
EP1004573A4 (de)	2000-10-18	Aryloxyanilin-derivate
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TR199902350T2 (xx)	2000-04-21	Yeni piridin t�revleri ve onlardan olu�an farmakotik bile�imler.
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DE60000978D1 (de)	2003-01-23	22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose
ATE86117T1 (de)	1993-03-15	Zusammensetzung gegen leberkrankheiten.
DE69806640D1 (de)	2002-08-22	17beta-aryl(arylmethyl)oxy(thio)alkyl-androstanderivative
ES2149180T3 (es)	2000-11-01	Derivado de pirazolotiazolopirimidina.
DE69303847D1 (de)	1996-09-05	Indolderivate
DE69903346D1 (de)	2002-11-07	22s-hydroxycholesta-8,14-dien derivate mit meiose regulierende aktivität