DK1007559T3 - Genetisk manipulerede celler, som udtrykker knoglemorfogene proteiner - Google Patents

Genetisk manipulerede celler, som udtrykker knoglemorfogene proteiner

Info

Publication number
DK1007559T3
DK1007559T3 DK98945924T DK98945924T DK1007559T3 DK 1007559 T3 DK1007559 T3 DK 1007559T3 DK 98945924 T DK98945924 T DK 98945924T DK 98945924 T DK98945924 T DK 98945924T DK 1007559 T3 DK1007559 T3 DK 1007559T3
Authority
DK
Denmark
Prior art keywords
cells expressing
genetically engineered
engineered cells
bone morphogenic
morphogenic proteins
Prior art date
Application number
DK98945924T
Other languages
English (en)
Inventor
Gadi Turgeman
Ioannis Moutsatsos
Dan Gazit
Yoram Zilberman
Original Assignee
Inst Genetics Llc
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Genetics Llc, Yissum Res Dev Co filed Critical Inst Genetics Llc
Application granted granted Critical
Publication of DK1007559T3 publication Critical patent/DK1007559T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK98945924T 1997-09-05 1998-09-04 Genetisk manipulerede celler, som udtrykker knoglemorfogene proteiner DK1007559T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5798997P 1997-09-05 1997-09-05
US09/148,234 US20020102728A1 (en) 1997-09-05 1998-09-04 Genetically engineered cells which express bone morphogenetic proteins

Publications (1)

Publication Number Publication Date
DK1007559T3 true DK1007559T3 (da) 2006-05-08

Family

ID=22013954

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98945924T DK1007559T3 (da) 1997-09-05 1998-09-04 Genetisk manipulerede celler, som udtrykker knoglemorfogene proteiner

Country Status (12)

Country Link
US (2) US20020102728A1 (da)
EP (1) EP1007559B1 (da)
JP (1) JP2001514026A (da)
AT (1) ATE314390T1 (da)
AU (1) AU752556B2 (da)
CA (1) CA2301882A1 (da)
DE (1) DE69832989T2 (da)
DK (1) DK1007559T3 (da)
ES (1) ES2255180T3 (da)
MX (1) MXPA00002318A (da)
PT (1) PT1007559E (da)
WO (1) WO1999011664A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8858981B2 (en) 1997-10-10 2014-10-14 Ed. Geistlich Soehne Fuer Chemistrie Industrie Bone healing material comprising matrix carrying bone-forming cells
US9034315B2 (en) 1997-10-10 2015-05-19 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Cell-charged multi-layer collagen membrane
US20050186283A1 (en) 1997-10-10 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
CA2379663A1 (en) * 1999-07-28 2001-02-08 Jamie M. Grooms Cartilage or bone matrix as a nucleic acid delivery vehicle
US6939540B1 (en) * 2000-07-31 2005-09-06 Cornell Research Foundation, Inc. Method of enhancing bone density
WO2003013588A1 (en) * 2001-08-08 2003-02-20 Kaken Pharmaceutical Co., Ltd. Kidney regeneration material comprising cells and cell growth factor
AU2002300450B2 (en) * 2001-08-10 2007-04-05 Ed. Geistlich Soehne Ag Fuer Chemische Industrie Collagen Carrier of Therapeutic Genetic Material, and Method
JP4097544B2 (ja) * 2003-02-27 2008-06-11 独立行政法人理化学研究所 人工リンパ節
AU2004255245B2 (en) * 2003-07-09 2009-10-22 Warsaw Orthopedic, Inc. Isolation of bone marrow fraction rich in connective tissue growth components and the use thereof to promote connective tissue formation
US20050272678A1 (en) * 2004-02-11 2005-12-08 Bodine Peter Van N BMP-6 estrogen responsive element and methods of use thereof
US7531355B2 (en) * 2005-07-29 2009-05-12 The Regents Of The University Of California Methods and compositions for smooth muscle reconstruction
WO2011060357A2 (en) * 2009-11-16 2011-05-19 The Ohio State University Engineered xenogeneic cells for repair of biological tissue
EP3359175B1 (en) 2015-10-05 2020-09-16 Salk Institute for Biological Studies Synthetic adenoviruses with tropism to damaged tissue for use in promoting wound repair and tissue regeneration

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763416A (en) * 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
US5942496A (en) * 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
WO1996039431A1 (en) * 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Bone morphogenic protein-10

Also Published As

Publication number Publication date
PT1007559E (pt) 2006-05-31
JP2001514026A (ja) 2001-09-11
AU9306298A (en) 1999-03-22
DE69832989T2 (de) 2006-08-24
AU752556B2 (en) 2002-09-19
EP1007559A1 (en) 2000-06-14
ES2255180T3 (es) 2006-06-16
ATE314390T1 (de) 2006-01-15
US20020102728A1 (en) 2002-08-01
CA2301882A1 (en) 1999-03-11
EP1007559B1 (en) 2005-12-28
US20110111505A1 (en) 2011-05-12
WO1999011664A1 (en) 1999-03-11
DE69832989D1 (de) 2006-02-02
MXPA00002318A (es) 2006-02-22

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