DK107086D0 - Peptider - Google Patents

Peptider

Info

Publication number
DK107086D0
DK107086D0 DK107086A DK107086A DK107086D0 DK 107086 D0 DK107086 D0 DK 107086D0 DK 107086 A DK107086 A DK 107086A DK 107086 A DK107086 A DK 107086A DK 107086 D0 DK107086 D0 DK 107086D0
Authority
DK
Denmark
Prior art keywords
insulin
charge
amino acid
neutral
insulin derivatives
Prior art date
Application number
DK107086A
Other languages
English (en)
Other versions
DK158677C (da
DK158677B (da
DK107086A (da
Inventor
Jan Markussen
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK107086A priority Critical patent/DK158677C/da
Publication of DK107086D0 publication Critical patent/DK107086D0/da
Publication of DK107086A publication Critical patent/DK107086A/da
Priority to US07/075,387 priority patent/US4946828A/en
Priority to US07/424,503 priority patent/US5008241A/en
Publication of DK158677B publication Critical patent/DK158677B/da
Application granted granted Critical
Publication of DK158677C publication Critical patent/DK158677C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK107086A 1985-03-12 1986-03-10 Insulinderivater og anvendelsen deraf, injicerbar oploesning indeholdende insulinderivaterne samt fremgangsmaade til fremstilling af oploesningen. DK158677C (da)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DK107086A DK158677C (da) 1985-03-12 1986-03-10 Insulinderivater og anvendelsen deraf, injicerbar oploesning indeholdende insulinderivaterne samt fremgangsmaade til fremstilling af oploesningen.
US07/075,387 US4946828A (en) 1985-03-12 1987-07-20 Novel insulin peptides
US07/424,503 US5008241A (en) 1985-03-12 1989-10-20 Novel insulin peptides

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK113585A DK113585D0 (da) 1985-03-12 1985-03-12 Nye peptider
DK113585 1985-03-12
DK107086 1986-03-10
DK107086A DK158677C (da) 1985-03-12 1986-03-10 Insulinderivater og anvendelsen deraf, injicerbar oploesning indeholdende insulinderivaterne samt fremgangsmaade til fremstilling af oploesningen.

Publications (4)

Publication Number Publication Date
DK107086D0 true DK107086D0 (da) 1986-03-10
DK107086A DK107086A (da) 1986-11-07
DK158677B DK158677B (da) 1990-07-02
DK158677C DK158677C (da) 1990-12-31

Family

ID=8101410

Family Applications (2)

Application Number Title Priority Date Filing Date
DK113585A DK113585D0 (da) 1985-03-12 1985-03-12 Nye peptider
DK107086A DK158677C (da) 1985-03-12 1986-03-10 Insulinderivater og anvendelsen deraf, injicerbar oploesning indeholdende insulinderivaterne samt fremgangsmaade til fremstilling af oploesningen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK113585A DK113585D0 (da) 1985-03-12 1985-03-12 Nye peptider

Country Status (22)

Country Link
EP (1) EP0194864B1 (da)
JP (1) JPS61212598A (da)
KR (1) KR930007433B1 (da)
CN (1) CN86101489A (da)
AT (1) ATE77391T1 (da)
AU (1) AU612964B2 (da)
CS (1) CS259536B2 (da)
DD (1) DD244345A5 (da)
DE (1) DE3685668T2 (da)
DK (2) DK113585D0 (da)
ES (1) ES8800276A1 (da)
FI (1) FI861007A7 (da)
GR (1) GR860687B (da)
HU (1) HU201097B (da)
IL (1) IL78103A0 (da)
MY (1) MY102102A (da)
NO (1) NO172441C (da)
NZ (1) NZ215445A (da)
PH (1) PH24260A (da)
PT (1) PT82173B (da)
YU (1) YU46001B (da)
ZA (1) ZA861432B (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
KR900701842A (ko) * 1988-07-20 1990-12-04 헨리 브뢰늄 인간 인슐린 동족체와 그를 포함하는 제제
DE3827533A1 (de) * 1988-08-13 1990-02-15 Hoechst Ag Pharmazeutische zubereitung zur behandlung des diabetes mellitus
DE3837825A1 (de) * 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
US5130298A (en) * 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
DE3936876A1 (de) * 1989-11-06 1991-05-23 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
AUPP609198A0 (en) * 1998-09-22 1998-10-15 Curtin University Of Technology Use of non-peptidyl compounds for the treatment of insulin related ailments
US6933272B1 (en) 1998-09-22 2005-08-23 Erik Helmerhorst Use of non-peptidyl compounds for the treatment of insulin related ailments
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de) 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
ES2642214T3 (es) 2004-01-21 2017-11-15 Novo Nordisk Health Care Ag Conjugación de péptidos mediante transglutaminasa
US20090074882A1 (en) 2005-12-28 2009-03-19 Novo Nordisk A/S Insulin compositions and method of making a composition
DE102006031955A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
DE102006031962A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
BRPI0907119A2 (pt) * 2008-01-09 2015-07-14 Sanofi Aventis Deutschland Derivados de insulina tendo um perfil de ação de tempo extremamente retardado
DE102008003566A1 (de) * 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
AU2009203809B2 (en) * 2008-01-09 2013-07-25 Sanofi-Aventis Deutschland Gmbh Novel insulin derivatives having an extremely delayed time-action profile
PT3228320T (pt) 2008-10-17 2020-03-26 Sanofi Aventis Deutschland Combinação de uma insulina e de um agonista do glp-1
TW201105346A (en) * 2009-07-06 2011-02-16 Sanofi Aventis Deutschland Heat-stable and vibration-stable insulin preparations
KR101853606B1 (ko) 2009-07-06 2018-05-03 사노피-아벤티스 도이칠란트 게엠베하 메티오닌을 함유하는 수성 인슐린 제제
KR101337322B1 (ko) 2009-11-13 2013-12-06 사노피-아벤티스 도이칠란트 게엠베하 Ｇｌｐ-1 효능제 및 메티오닌을 포함하는 약제학적 조성물
DK2498802T3 (da) 2009-11-13 2015-04-13 Sanofi Aventis Deutschland Farmaceutisk præparat omfattende en glp-1-agonist, et insulin og en methionin
JP6249773B2 (ja) * 2010-05-10 2017-12-20 ノヴォ ノルディスク アー／エス インスリン−亜鉛錯体の調製方法
ES2606554T3 (es) 2010-08-30 2017-03-24 Sanofi-Aventis Deutschland Gmbh Uso de AVE0010 para la fabricación de un medicamento para el tratamiento de la diabetes mellitus de tipo 2
CN102174495A (zh) * 2011-01-20 2011-09-07 马忠仁 一种提取糜胰蛋白酶的方法
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PL2750699T3 (pl) 2011-08-29 2015-12-31 Sanofi Aventis Deutschland Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
AU2015359376B2 (en) 2014-12-12 2021-09-09 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
US12343383B2 (en) 2019-07-12 2025-07-01 Novo Nordisk A/S High concentration insulin formulation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat

Also Published As

Publication number Publication date
CN86101489A (zh) 1987-01-21
IL78103A0 (en) 1986-07-31
PT82173B (pt) 1988-07-29
ES8800276A1 (es) 1987-11-01
DE3685668T2 (de) 1993-01-14
DE3685668D1 (en) 1992-07-23
NO172441B (no) 1993-04-13
PH24260A (en) 1990-05-04
NO860920L (no) 1986-09-15
DD244345A5 (de) 1987-04-01
PT82173A (en) 1986-04-01
MY102102A (en) 1992-03-31
FI861007L (fi) 1986-09-13
DK158677C (da) 1990-12-31
NZ215445A (en) 1989-07-27
CS259536B2 (en) 1988-10-14
DK113585D0 (da) 1985-03-12
EP0194864B1 (en) 1992-06-17
CS166686A2 (en) 1987-12-17
YU46001B (sh) 1992-12-21
AU612964B2 (en) 1991-07-25
EP0194864A2 (en) 1986-09-17
ZA861432B (en) 1986-11-26
KR930007433B1 (ko) 1993-08-10
ES552879A0 (es) 1987-11-01
FI861007A7 (fi) 1986-09-13
KR860007288A (ko) 1986-10-10
JPS61212598A (ja) 1986-09-20
YU34586A (en) 1988-10-31
GR860687B (en) 1986-07-11
HUT41052A (en) 1987-03-30
EP0194864A3 (en) 1989-01-11
HU201097B (en) 1990-09-28
FI861007A0 (fi) 1986-03-11
DK158677B (da) 1990-07-02
NO172441C (no) 1993-07-21
AU5449586A (en) 1986-09-18
DK107086A (da) 1986-11-07
ATE77391T1 (de) 1992-07-15

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