DK1022272T3 - Substituerede, fusionerede, heterocykliske forbindelser - Google Patents

Substituerede, fusionerede, heterocykliske forbindelser

Info

Publication number: DK1022272T3
Authority: DK; Denmark
Prior art keywords: group; hydrogen atom; substituted; chem; oxygen
Prior art date: 1997-10-08

Application number

DK98947789T

Other languages

Danish (da)

English (en)

Inventor

Takashi Fujita

Kunio Wada

Toshihiko Fujiwara

Original Assignee

Sankyo Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-08

Filing date

1998-10-08

Publication date

2004-09-27

1998-10-08 Application filed by Sankyo Co filed Critical Sankyo Co

2004-09-27 Application granted granted Critical

2004-09-27 Publication of DK1022272T3 publication Critical patent/DK1022272T3/da

Links

150000002391 heterocyclic compounds Chemical class 0.000 title abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
230000002401 inhibitory effect Effects 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
229910052717 sulfur Inorganic materials 0.000 abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
-1 2,4-dioxothiazolidin-5-ylmethyl group Chemical group 0.000 abstract 1
102000001381 Arachidonate 5-Lipoxygenase Human genes 0.000 abstract 1
108010093579 Arachidonate 5-lipoxygenase Proteins 0.000 abstract 1
MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
206010022489 Insulin Resistance Diseases 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1
125000004434 sulfur atom Chemical group 0.000 abstract 1
208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Obesity (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Joining Of Building Structures In Genera (AREA)

DK98947789T 1997-10-08 1998-10-08 Substituerede, fusionerede, heterocykliske forbindelser DK1022272T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP27606397		1997-10-08

Publications (1)

Publication Number	Publication Date
DK1022272T3 true DK1022272T3 (da)	2004-09-27

Family

ID=17564291

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98947789T DK1022272T3 (da)	1997-10-08	1998-10-08	Substituerede, fusionerede, heterocykliske forbindelser

Country Status (24)

Country	Link
US (1)	US6432993B1 (fr)
EP (1)	EP1022272B1 (fr)
KR (1)	KR100666887B1 (fr)
CN (1)	CN1255386C (fr)
AT (1)	ATE267814T1 (fr)
AU (1)	AU740704B2 (fr)
BR (1)	BR9813848B1 (fr)
CA (1)	CA2305807C (fr)
CZ (1)	CZ302475B6 (fr)
DE (1)	DE69824194T2 (fr)
DK (1)	DK1022272T3 (fr)
ES (1)	ES2221203T3 (fr)
HU (1)	HU228193B1 (fr)
ID (1)	ID23891A (fr)
IL (1)	IL135537A (fr)
MX (1)	MXPA00003546A (fr)
NO (1)	NO318070B1 (fr)
NZ (1)	NZ503794A (fr)
PL (1)	PL200859B1 (fr)
PT (1)	PT1022272E (fr)
RU (1)	RU2196141C2 (fr)
TR (1)	TR200000946T2 (fr)
TW (1)	TW475931B (fr)
WO (1)	WO1999018081A1 (fr)

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1998
- 1998-10-08 KR KR1020007003711A patent/KR100666887B1/ko not_active Expired - Fee Related
- 1998-10-08 IL IL135537A patent/IL135537A/en not_active IP Right Cessation
- 1998-10-08 HU HU0003859A patent/HU228193B1/hu unknown
- 1998-10-08 AT AT98947789T patent/ATE267814T1/de active
- 1998-10-08 DK DK98947789T patent/DK1022272T3/da active
- 1998-10-08 DE DE1998624194 patent/DE69824194T2/de not_active Expired - Lifetime
- 1998-10-08 TW TW087116711A patent/TW475931B/zh not_active IP Right Cessation
- 1998-10-08 BR BRPI9813848-0A patent/BR9813848B1/pt not_active IP Right Cessation
- 1998-10-08 EP EP98947789A patent/EP1022272B1/fr not_active Expired - Lifetime
- 1998-10-08 CN CNB988116928A patent/CN1255386C/zh not_active Expired - Fee Related
- 1998-10-08 AU AU94587/98A patent/AU740704B2/en not_active Ceased
- 1998-10-08 PL PL339771A patent/PL200859B1/pl not_active IP Right Cessation
- 1998-10-08 CA CA002305807A patent/CA2305807C/fr not_active Expired - Fee Related
- 1998-10-08 RU RU2000109326/04A patent/RU2196141C2/ru not_active IP Right Cessation
- 1998-10-08 ID IDW20000649A patent/ID23891A/id unknown
- 1998-10-08 PT PT98947789T patent/PT1022272E/pt unknown
- 1998-10-08 TR TR2000/00946T patent/TR200000946T2/xx unknown
- 1998-10-08 WO PCT/JP1998/004548 patent/WO1999018081A1/fr not_active Ceased
- 1998-10-08 MX MXPA00003546A patent/MXPA00003546A/es active IP Right Grant
- 1998-10-08 NZ NZ503794A patent/NZ503794A/xx not_active IP Right Cessation
- 1998-10-08 ES ES98947789T patent/ES2221203T3/es not_active Expired - Lifetime
- 1998-10-08 CZ CZ20001219A patent/CZ302475B6/cs not_active IP Right Cessation
2000
- 2000-04-07 US US09/543,667 patent/US6432993B1/en not_active Expired - Lifetime
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Also Published As

Publication number	Publication date
CA2305807C (fr)	2008-01-22
CN1255386C (zh)	2006-05-10
ATE267814T1 (de)	2004-06-15
DE69824194D1 (de)	2004-07-01
HUP0003859A2 (hu)	2001-08-28
CN1280570A (zh)	2001-01-17
EP1022272A4 (fr)	2002-07-17
NO20001816D0 (no)	2000-04-07
HK1027354A1 (en)	2001-01-12
TR200000946T2 (tr)	2000-07-21
ID23891A (id)	2000-05-25
PL339771A1 (en)	2001-01-02
KR100666887B1 (ko)	2007-01-10
DE69824194T2 (de)	2005-01-13
NO20001816L (no)	2000-06-07
EP1022272B1 (fr)	2004-05-26
RU2196141C2 (ru)	2003-01-10
EP1022272A1 (fr)	2000-07-26
ES2221203T3 (es)	2004-12-16
PT1022272E (pt)	2004-08-31
PL200859B1 (pl)	2009-02-27
TW475931B (en)	2002-02-11
KR20010030961A (ko)	2001-04-16
IL135537A (en)	2006-08-20
AU740704B2 (en)	2001-11-15
MXPA00003546A (es)	2002-08-06
NZ503794A (en)	2002-09-27
HUP0003859A3 (en)	2005-09-28
US6432993B1 (en)	2002-08-13
AU9458798A (en)	1999-04-27
BR9813848A (pt)	2000-10-03
CA2305807A1 (fr)	1999-04-15
NO318070B1 (no)	2005-01-31
BR9813848B1 (pt)	2011-07-12
CZ302475B6 (cs)	2011-06-08
IL135537A0 (en)	2001-05-20
WO1999018081A1 (fr)	1999-04-15
HU228193B1 (en)	2013-01-28
CZ20001219A3 (cs)	2000-08-16

Publication	Publication Date	Title
PT1022272E (pt)	2004-08-31	Compostos heterociclicos fundidos substituidos
ATE401312T1 (de)	2008-08-15	Pyrimidin-5-carboxamid-derivate
DK1323710T3 (da)	2008-12-01	Nitrogenholdige femleddede ringforbindelser
ATE271045T1 (de)	2004-07-15	Sauerstoffhaltige heterocyclische verbindungen
DK0979821T3 (da)	2007-01-29	Tricykliske forbindelser
DE69813605D1 (de)	2003-05-22	Benzofuranderivate
DK0695755T3 (da)	1999-06-28	Pyrrolocarbazoler
NO974588D0 (no)	1997-10-03	Triazol-antifungaltmiddel
ATE504572T1 (de)	2011-04-15	Derivate von aromatische heterocyclen enthaltende integraseinhibitoren
DE69915514D1 (de)	2004-04-15	Prenyltransferase-inhibitoren
ATE161820T1 (de)	1998-01-15	Carboxylatderivate mit einer die phospholipase a2 hemmenden aktivität
ATE284884T1 (de)	2005-01-15	Triazolderivate mit amidbindungen
EG19396A (en)	1995-01-31	Pesticidal heterocyclic compounds
ATE119523T1 (de)	1995-03-15	Isochinolinderivate und ihre salze als proteasehemmer.
ATE30916T1 (de)	1987-12-15	Fungizide heterocyclische verbindungen.