DK1022337T3 - Plasmider, deres konstruktion og deres anvendelse til fremstilling af interleukin-4 og interleukin-4-muteiner - Google Patents

Plasmider, deres konstruktion og deres anvendelse til fremstilling af interleukin-4 og interleukin-4-muteiner

Info

Publication number
DK1022337T3
DK1022337T3 DK00100129T DK00100129T DK1022337T3 DK 1022337 T3 DK1022337 T3 DK 1022337T3 DK 00100129 T DK00100129 T DK 00100129T DK 00100129 T DK00100129 T DK 00100129T DK 1022337 T3 DK1022337 T3 DK 1022337T3
Authority
DK
Denmark
Prior art keywords
interleukin
muteins
construction
plasmids
preparation
Prior art date
Application number
DK00100129T
Other languages
Danish (da)
English (en)
Inventor
Heiner Dr Apeler
Hermann Dr Wehlmann
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Application granted granted Critical
Publication of DK1022337T3 publication Critical patent/DK1022337T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK00100129T 1999-01-20 2000-01-07 Plasmider, deres konstruktion og deres anvendelse til fremstilling af interleukin-4 og interleukin-4-muteiner DK1022337T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99100967A EP1022339B1 (fr) 1999-01-20 1999-01-20 Plasmides, leur construction et utilisation pour la préparation d'Interleukine-4 et ses mutéines

Publications (1)

Publication Number Publication Date
DK1022337T3 true DK1022337T3 (da) 2006-11-06

Family

ID=8237378

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00100129T DK1022337T3 (da) 1999-01-20 2000-01-07 Plasmider, deres konstruktion og deres anvendelse til fremstilling af interleukin-4 og interleukin-4-muteiner

Country Status (15)

Country Link
US (1) US6506590B1 (fr)
EP (1) EP1022339B1 (fr)
JP (2) JP2000210091A (fr)
KR (1) KR100665148B1 (fr)
AT (1) ATE334202T1 (fr)
AU (1) AU772897B2 (fr)
CA (1) CA2294575C (fr)
CZ (1) CZ294279B6 (fr)
DE (1) DE69929638T2 (fr)
DK (1) DK1022337T3 (fr)
ES (1) ES2269027T3 (fr)
HU (1) HU224491B1 (fr)
NO (1) NO327317B1 (fr)
PT (1) PT1022337E (fr)
SK (1) SK285603B6 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10022258A1 (de) 2000-05-08 2001-11-15 Bayer Ag Reinigung von Proteineinschlusskörpern durch Querstrom-Mikrofiltration
KR100443570B1 (ko) * 2001-07-31 2004-08-09 크레아젠 주식회사 재조합 인간 인터루킨-4의 제조방법
EP1314739A1 (fr) 2001-11-22 2003-05-28 Bayer Ag Procédé de renaturation de protéines recombinantes renfermant des liasons disulfure, à des concentrations élevées de protéines en présence d'amines
JP2006055082A (ja) * 2004-08-20 2006-03-02 National Institute Of Advanced Industrial & Technology 発光甲虫由来赤色発光酵素安定体の生産及び精製法
CN118440969B (zh) * 2024-07-08 2024-10-15 天津凯莱英生物科技有限公司 可溶性表达质粒突变体库的构建方法及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689406A (en) * 1983-08-10 1987-08-25 Amgen Enhancement of microbial expression of polypeptides
EP0241446B1 (fr) * 1986-03-27 1995-03-01 Monsanto Company Production stimulée de protéines par des bactéries, par utilisation d'un nouveau site de fixation de ribosomes
DK443288A (da) * 1987-08-17 1989-02-18 Hoffmann La Roche Ekspressionskontrolsekvenser
FR2724665B1 (fr) * 1994-09-16 1996-12-20 Rhone Poulenc Rorer Sa Procede de production de proteines recombinantes, plasmides et cellules modifiees
MY124565A (en) * 1996-07-19 2006-06-30 Bayer Corp High-affinity interleukin-4-muteins

Also Published As

Publication number Publication date
NO20000262D0 (no) 2000-01-19
CA2294575A1 (fr) 2000-07-20
DE69929638D1 (de) 2006-04-13
SK762000A3 (en) 2000-08-14
JP2010284174A (ja) 2010-12-24
US6506590B1 (en) 2003-01-14
CA2294575C (fr) 2009-04-07
KR100665148B1 (ko) 2007-01-09
CZ2000214A3 (cs) 2000-08-16
ES2269027T3 (es) 2007-04-01
CZ294279B6 (cs) 2004-11-10
NO20000262L (no) 2000-07-21
HUP0000185A2 (en) 2002-09-28
AU772897B2 (en) 2004-05-13
HU224491B1 (hu) 2005-09-28
KR20000053523A (ko) 2000-08-25
PT1022337E (pt) 2006-11-30
SK285603B6 (sk) 2007-04-05
HU0000185D0 (en) 2000-04-28
AU1250700A (en) 2000-07-27
EP1022339B1 (fr) 2006-02-01
DE69929638T2 (de) 2006-09-21
NO327317B1 (no) 2009-06-08
ATE334202T1 (de) 2006-08-15
EP1022339A1 (fr) 2000-07-26
JP2000210091A (ja) 2000-08-02

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