DK1030842T3 - Metalloproteinaseinhibitorer - Google Patents
MetalloproteinaseinhibitorerInfo
- Publication number
- DK1030842T3 DK1030842T3 DK97912351T DK97912351T DK1030842T3 DK 1030842 T3 DK1030842 T3 DK 1030842T3 DK 97912351 T DK97912351 T DK 97912351T DK 97912351 T DK97912351 T DK 97912351T DK 1030842 T3 DK1030842 T3 DK 1030842T3
- Authority
- DK
- Denmark
- Prior art keywords
- methoxysuccinamide
- pyridin
- isobutyl
- propyl
- hydroxy
- Prior art date
Links
- 102000005741 Metalloproteases Human genes 0.000 title 1
- 108010006035 Metalloproteases Proteins 0.000 title 1
- 208000001382 Experimental Melanoma Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000002456 anti-arthritic effect Effects 0.000 abstract 1
- 230000002682 anti-psoriatic effect Effects 0.000 abstract 1
- 230000003356 anti-rheumatic effect Effects 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 239000000824 cytostatic agent Substances 0.000 abstract 1
- 230000001085 cytostatic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 229940121386 matrix metalloproteinase inhibitor Drugs 0.000 abstract 1
- 239000003771 matrix metalloproteinase inhibitor Substances 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
- 230000003204 osmotic effect Effects 0.000 abstract 1
- 230000036470 plasma concentration Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Lubricants (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pyridine Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB1997/003132 WO1999025693A1 (en) | 1997-11-13 | 1997-11-13 | Metalloproteinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1030842T3 true DK1030842T3 (da) | 2003-07-28 |
Family
ID=10807699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97912351T DK1030842T3 (da) | 1997-11-13 | 1997-11-13 | Metalloproteinaseinhibitorer |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1030842B1 (da) |
| JP (1) | JP2001523666A (da) |
| KR (1) | KR100485479B1 (da) |
| AT (1) | ATE236126T1 (da) |
| AU (1) | AU740420B2 (da) |
| BR (1) | BR9714934A (da) |
| CA (1) | CA2310593C (da) |
| DE (1) | DE69720554T2 (da) |
| DK (1) | DK1030842T3 (da) |
| ES (1) | ES2195122T3 (da) |
| GB (1) | GB2333524A (da) |
| HU (1) | HUP0002811A3 (da) |
| IL (1) | IL135210A0 (da) |
| NO (1) | NO315702B1 (da) |
| NZ (1) | NZ503642A (da) |
| PL (1) | PL189542B1 (da) |
| PT (1) | PT1030842E (da) |
| RU (1) | RU2198164C2 (da) |
| TR (1) | TR200001353T2 (da) |
| TW (1) | TW474919B (da) |
| WO (1) | WO1999025693A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20030701A1 (es) | 2001-12-20 | 2003-08-21 | Schering Corp | Compuestos para el tratamiento de trastornos inflamatorios |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2024507C1 (ru) * | 1991-11-18 | 1994-12-15 | Евгений Яковлевич Левитин | 5-хлор-2-пиридиламид-4-нитро-n-(карбоксиметил)антраниловой кислоты, проявляющий противовоспалительную активность |
| PT822186E (pt) * | 1994-01-20 | 2000-08-31 | British Biotech Pharm | L-tert-leucina-2-piridilamida |
| WO1997003966A1 (en) * | 1995-07-19 | 1997-02-06 | British Biotech Pharmaceuticals Limited | N-(amino acid) substituted succinic acid amide derivatives as metalloproteinase inhibitors |
-
1997
- 1997-11-13 NZ NZ503642A patent/NZ503642A/en unknown
- 1997-11-13 WO PCT/GB1997/003132 patent/WO1999025693A1/en not_active Ceased
- 1997-11-13 AU AU49584/97A patent/AU740420B2/en not_active Ceased
- 1997-11-13 GB GB9816317A patent/GB2333524A/en not_active Withdrawn
- 1997-11-13 PL PL97340494A patent/PL189542B1/pl not_active IP Right Cessation
- 1997-11-13 JP JP2000521077A patent/JP2001523666A/ja not_active Withdrawn
- 1997-11-13 CA CA002310593A patent/CA2310593C/en not_active Expired - Fee Related
- 1997-11-13 DK DK97912351T patent/DK1030842T3/da active
- 1997-11-13 TR TR2000/01353T patent/TR200001353T2/xx unknown
- 1997-11-13 RU RU2000114634/04A patent/RU2198164C2/ru not_active IP Right Cessation
- 1997-11-13 AT AT97912351T patent/ATE236126T1/de not_active IP Right Cessation
- 1997-11-13 PT PT97912351T patent/PT1030842E/pt unknown
- 1997-11-13 HU HU0002811A patent/HUP0002811A3/hu unknown
- 1997-11-13 BR BR9714934-9A patent/BR9714934A/pt not_active Application Discontinuation
- 1997-11-13 KR KR10-2000-7004964A patent/KR100485479B1/ko not_active Expired - Fee Related
- 1997-11-13 EP EP97912351A patent/EP1030842B1/en not_active Expired - Lifetime
- 1997-11-13 IL IL13521097A patent/IL135210A0/xx not_active IP Right Cessation
- 1997-11-13 ES ES97912351T patent/ES2195122T3/es not_active Expired - Lifetime
- 1997-11-13 DE DE69720554T patent/DE69720554T2/de not_active Expired - Fee Related
- 1997-12-02 TW TW086118078A patent/TW474919B/zh not_active IP Right Cessation
-
2000
- 2000-05-12 NO NO20002480A patent/NO315702B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20002480L (no) | 2000-05-12 |
| PL340494A1 (en) | 2001-02-12 |
| EP1030842A1 (en) | 2000-08-30 |
| DE69720554T2 (de) | 2004-01-08 |
| WO1999025693A1 (en) | 1999-05-27 |
| ATE236126T1 (de) | 2003-04-15 |
| AU740420B2 (en) | 2001-11-01 |
| CA2310593A1 (en) | 1999-05-27 |
| DE69720554D1 (de) | 2003-05-08 |
| PL189542B1 (pl) | 2005-08-31 |
| TW474919B (en) | 2002-02-01 |
| GB2333524A (en) | 1999-07-28 |
| TR200001353T2 (tr) | 2000-10-23 |
| PT1030842E (pt) | 2003-07-31 |
| KR20010031879A (ko) | 2001-04-16 |
| HUP0002811A3 (en) | 2002-11-28 |
| NZ503642A (en) | 2001-10-26 |
| NO20002480D0 (no) | 2000-05-12 |
| RU2198164C2 (ru) | 2003-02-10 |
| EP1030842B1 (en) | 2003-04-02 |
| JP2001523666A (ja) | 2001-11-27 |
| CA2310593C (en) | 2007-05-08 |
| ES2195122T3 (es) | 2003-12-01 |
| BR9714934A (pt) | 2000-10-03 |
| AU4958497A (en) | 1999-06-07 |
| NO315702B1 (no) | 2003-10-13 |
| IL135210A0 (en) | 2001-05-20 |
| GB9816317D0 (en) | 1998-09-23 |
| KR100485479B1 (ko) | 2005-04-27 |
| HUP0002811A2 (hu) | 2001-01-29 |
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