DK1032379T3 - Præparat med azelainsyre - Google Patents

Præparat med azelainsyre

Info

Publication number: DK1032379T3
Authority: DK; Denmark
Prior art keywords: azelaic acid; preparation; composition; presbyderma; triacylglyceride
Prior art date: 1997-11-19

Application number

DK98962351T

Other languages

Danish (da)

English (en)

Inventor

Patrick Franke

Clemens Guenther

Jutta Riedl

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-19

Filing date

1998-11-18

Publication date

2002-04-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27217979&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1032379(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-11-18 Application filed by Schering Ag filed Critical Schering Ag

2002-04-02 Application granted granted Critical

2002-04-02 Publication of DK1032379T3 publication Critical patent/DK1032379T3/da

Links

BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical compound OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 title abstract 4
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
206010008570 Chloasma Diseases 0.000 abstract 1
208000003351 Melanosis Diseases 0.000 abstract 1
241001303601 Rosacea Species 0.000 abstract 1
206010040880 Skin irritation Diseases 0.000 abstract 1
229920002125 Sokalan® Polymers 0.000 abstract 1
239000000470 constituent Substances 0.000 abstract 1
239000000017 hydrogel Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000004584 polyacrylic acid Substances 0.000 abstract 1
229950008882 polysorbate Drugs 0.000 abstract 1
229920000136 polysorbate Polymers 0.000 abstract 1
201000004700 rosacea Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000036556 skin irritation Effects 0.000 abstract 1
231100000475 skin irritation Toxicity 0.000 abstract 1
239000008347 soybean phospholipid Substances 0.000 abstract 1
150000003626 triacylglycerols Chemical class 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK98962351T 1997-11-19 1998-11-18 Præparat med azelainsyre DK1032379T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
DE19753044		1997-11-19
US7485098P	1998-02-12	1998-02-12
DE19808086		1998-02-20
PCT/EP1998/007370 WO1999025332A1 (de)	1997-11-19	1998-11-18	Zusammensetzung mit azelainsäure

Publications (1)

Publication Number	Publication Date
DK1032379T3 true DK1032379T3 (da)	2002-04-02

Family

ID=27217979

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98962351T DK1032379T3 (da)	1997-11-19	1998-11-18	Præparat med azelainsyre

Country Status (21)

Country	Link
US (1)	US6534070B1 (cs)
EP (1)	EP1032379B1 (cs)
JP (1)	JP3867123B2 (cs)
KR (1)	KR100534511B1 (cs)
AT (1)	ATE210438T1 (cs)
AU (1)	AU743437B2 (cs)
BR (1)	BR9814214B1 (cs)
CA (1)	CA2311128C (cs)
CZ (1)	CZ299116B6 (cs)
DE (2)	DE59802473D1 (cs)
DK (1)	DK1032379T3 (cs)
ES (1)	ES2169566T3 (cs)
HU (1)	HU226592B1 (cs)
IL (1)	IL136101A (cs)
IS (1)	IS2257B (cs)
NO (1)	NO327712B1 (cs)
PL (1)	PL202454B1 (cs)
PT (1)	PT1032379E (cs)
SK (1)	SK284338B6 (cs)
TR (1)	TR200001393T2 (cs)
WO (1)	WO1999025332A1 (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE369866T1 (de) *	2003-06-10	2007-09-15	Intendis Gmbh	Zusammensetzung aus alkandicarbonsäuren und einem pharmazeutischen wirkstoff
US20050026982A1 (en) *	2003-06-10	2005-02-03	Soenke Johannsen	Composition that consists of alkanedicarboxylic acids and a pharmaceutical active ingredient
ATE347367T1 (de) *	2003-10-13	2006-12-15	Zoser B Salama	Pharmazeutische zusammensetzung umfassend oxoplatin und dessen salze
DE10356288B4 (de)	2003-11-28	2014-04-03	Siemens Aktiengesellschaft	Röntgendetektorlade
CA2600054A1 (en) *	2005-03-09	2006-09-21	Combe Incorporated	Stable mixed emulsions
CA2600288A1 (en) *	2005-09-19	2007-04-12	Combe Incorporated	Stable emulsion systems with high salt tolerance
KR100861978B1 (ko) *	2007-03-22	2008-10-07	한국콜마 주식회사	아젤라산을 이용한 여드름 치료용 화장료 조성물 및 그 제조방법
US8729108B2 (en) *	2008-06-17	2014-05-20	Christopher J Dannaker	Waterborne topical compositions for the delivery of active ingredients such as azelaic acid
EP2201930A1 (en) *	2008-12-23	2010-06-30	Intendis GmbH	Hydrogel composition for the treatment of dermatological disorders
US20100247693A1 (en) *	2009-03-24	2010-09-30	Marini Jan L	Cosmetic formulation to treat rosacea telangiectasia
PL217786B1 (pl) *	2009-05-28	2014-08-29	P P F Hasco Lek Spółka Akcyjna	Żel z kwasem azelainowym i sposób wytwarzania żelu z kwasem azelainowym
GB2486371A (en)	2009-08-21	2012-06-13	Targeted Delivery Technologies Ltd	Vesicular formulations
DE102010021671A1 (de)	2010-05-27	2011-12-01	Intendis Gmbh	Azelainsäurehaltige Formulierung mit Pigmentzusatz
GB201205642D0 (en) *	2012-03-29	2012-05-16	Sequessome Technology Holdings Ltd	Vesicular formulations
GB201208409D0 (en) *	2012-05-14	2012-06-27	Sequessome Technology Holdings Ltd	Vesicular formulations, kits and uses
ES2895910T3 (es)	2015-06-30	2022-02-23	Sequessome Tech Holdings Limited	Composiciones multifásicas
US11198831B2 (en)	2019-01-31	2021-12-14	Kvi Llc	Lubricant for a device
CN116747147B (zh) *	2023-04-27	2025-10-17	南京市苗本堂健康管理有限公司	一种靶向祛痘的壬二酸微纳晶混悬液及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3811081A1 (de)	1988-03-30	1989-10-12	Schering Ag	Verwendung von topisch applizierbaren praeparaten zur behandlung der altershaut
EP0510165B1 (fr) *	1990-11-14	1995-01-25	L'oreal	Composes amphiphiles non-ioniques derives du glycerol, leur procede de preparation, composes intermediaires correspondants et compositions contenant lesdits composes
GB9316323D0 (en) *	1993-08-06	1993-09-22	Procter & Gamble	Cosmetic compositions
US5744155A (en)	1993-08-13	1998-04-28	Friedman; Doron	Bioadhesive emulsion preparations for enhanced drug delivery
WO1995011700A1 (en)	1993-10-29	1995-05-04	Pharmos Corp.	Submicron emulsions as vaccine adjuvants
ES2094688B1 (es)	1994-08-08	1997-08-01	Cusi Lab	Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion.
US5547989A (en)	1994-08-19	1996-08-20	Schering-Plough Healthcare Products, Inc.	Compositions for treating corns and calluses
US5618522A (en) *	1995-01-20	1997-04-08	The Procter & Gamble Company	Emulsion compositions
UY24246A1 (es) *	1995-06-06	1996-06-14	Neutrogena Corp	Vehiculos tropicos que contienen acido azelaico solubilizado y estabilizado

1998
- 1998-11-18 US US09/554,738 patent/US6534070B1/en not_active Expired - Lifetime
- 1998-11-18 AT AT98962351T patent/ATE210438T1/de active
- 1998-11-18 CZ CZ20001844A patent/CZ299116B6/cs not_active IP Right Cessation
- 1998-11-18 HU HU0004375A patent/HU226592B1/hu unknown
- 1998-11-18 EP EP98962351A patent/EP1032379B1/de not_active Expired - Lifetime
- 1998-11-18 JP JP2000520766A patent/JP3867123B2/ja not_active Expired - Lifetime
- 1998-11-18 BR BRPI9814214-3A patent/BR9814214B1/pt not_active IP Right Cessation
- 1998-11-18 TR TR2000/01393T patent/TR200001393T2/xx unknown
- 1998-11-18 KR KR10-2000-7005430A patent/KR100534511B1/ko not_active Expired - Lifetime
- 1998-11-18 DK DK98962351T patent/DK1032379T3/da active
- 1998-11-18 ES ES98962351T patent/ES2169566T3/es not_active Expired - Lifetime
- 1998-11-18 PL PL340631A patent/PL202454B1/pl unknown
- 1998-11-18 SK SK708-2000A patent/SK284338B6/sk not_active IP Right Cessation
- 1998-11-18 CA CA002311128A patent/CA2311128C/en not_active Expired - Lifetime
- 1998-11-18 PT PT98962351T patent/PT1032379E/pt unknown
- 1998-11-18 DE DE59802473T patent/DE59802473D1/de not_active Expired - Lifetime
- 1998-11-18 WO PCT/EP1998/007370 patent/WO1999025332A1/de not_active Ceased
- 1998-11-18 DE DE19881737T patent/DE19881737D2/de not_active Ceased
- 1998-11-18 IL IL13610198A patent/IL136101A/xx not_active IP Right Cessation
- 1998-11-18 AU AU17551/99A patent/AU743437B2/en not_active Expired
2000
- 2000-05-09 IS IS5484A patent/IS2257B/is unknown
- 2000-05-12 NO NO20002487A patent/NO327712B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20010032229A (ko)	2001-04-16
BR9814214B1 (pt)	2010-07-13
PT1032379E (pt)	2002-06-28
ES2169566T3 (es)	2002-07-01
CZ299116B6 (cs)	2008-04-30
JP2001522879A (ja)	2001-11-20
HU226592B1 (en)	2009-04-28
CZ20001844A3 (cs)	2000-10-11
NO327712B1 (no)	2009-09-14
KR100534511B1 (ko)	2005-12-08
TR200001393T2 (tr)	2000-10-23
AU1755199A (en)	1999-06-07
CA2311128C (en)	2008-01-29
EP1032379A1 (de)	2000-09-06
US6534070B1 (en)	2003-03-18
DE59802473D1 (de)	2002-01-24
IL136101A (en)	2005-08-31
JP3867123B2 (ja)	2007-01-10
BR9814214A (pt)	2000-10-03
HUP0004375A2 (hu)	2001-08-28
IS5484A (is)	2000-05-09
CA2311128A1 (en)	1999-05-27
PL202454B1 (pl)	2009-06-30
WO1999025332A1 (de)	1999-05-27
EP1032379B1 (de)	2001-12-12
NO20002487D0 (no)	2000-05-12
SK284338B6 (sk)	2005-02-04
AU743437B2 (en)	2002-01-24
NO20002487L (no)	2000-07-18
PL340631A1 (en)	2001-02-12
SK7082000A3 (en)	2001-06-11
DE19881737D2 (de)	2001-03-22
IS2257B (is)	2007-06-15
IL136101A0 (en)	2001-05-20
ATE210438T1 (de)	2001-12-15
HUP0004375A3 (en)	2006-06-28

Publication	Publication Date	Title
DK1032379T3 (da)	2002-04-02	Præparat med azelainsyre
TR200000576T1 (tr)	2000-11-21	Lipozomal kapsüllenmiş taksan uygulanması için bir yöntem
DK0839026T3 (da)	2002-01-21	Micellære polyether-blokcopolymerkompositioner til målretning af biologiske midler
BR9916694A (pt)	2001-12-11	Composição de lenço facial e método de uso parasequestração de irritantes cutâneos de secreçãonasal
BR9911076A (pt)	2001-02-20	Uso de peg-ifn-alfa e ribavirina para o tratamento de hepatite c crÈnica
AR002974A1 (es)	1998-05-27	Utilización de por lo menos un antagonista de cgrppara la preparación de una composición cosmética, farmacéutica y/o dermatológica para tratar las manchas rojas cutáneas de origen neurógeno, composición obtenida y procedimiento de tratamiento cosmético empleando dicho antagonista.
DK261490D0 (da)	1990-10-31	New pharmaceutical compound
TR200201089T2 (tr)	2002-09-23	Dipiridamol veya mopidamolün fibrine bağlı mikrodolaşım bozukluklarının tedavisi
ES2160643T3 (es)	2001-11-16	Composiciones que contienen g-csf y proteina de union al tnf.
BR9811298A (pt)	2000-08-29	Uso de um composto de vanádio fisiologicamente aceitável
BRPI0409699A (pt)	2006-04-18	métodos de indução do efeito diurético, de indução, manutenção ou restauração do efeito diurético de diurético não modificador de adenosina, de manutenção, restauração ou melhoria da função renal em paciente, de indução de diurese, de prevenção do inìcio de deficiência renal em paciente com sobrecarga de fluidos ou chf, de tratamento de paciente que sofre de chf e de melhoria dos resultados globais da saúde, composição farmacêutica e seus usos
ATE395064T1 (de)	2008-05-15	Kombinationspräparate von 3-n- formylhydroxylaminopropylphosphonsäurederivaten oder 3-n- acetylhydroxylaminopropylphosphonsäurederivaten mit speziellen pharmazeutischen wirkstoffen
BR9701455A (pt)	1998-08-18	Uso de antagonistas de bradicinina para a preparaçao de medicamentos para o tratamento de doenças fibrogenéticas crônicas do fígado e doenças agudas do fígado
ES283591Y (es)	1986-04-01	Una tableta de dosificacion farmaceutica adecuada para administracion oral
MY129121A (en)	2007-03-30	Composition with azelaic acid
AU6725300A (en)	2001-04-10	Non-hygroscopic salts of active ingredients having therapeutical and/or nutritional activities and orally administrable compositions containing same
WO2000010590A3 (en)	2000-05-18	Cancer treatment
FR2547730B1 (fr)	1987-11-13	Medicament hypolipidemiant contenant comme ingredient actif la d-3-acetoxy-cis-2,3-dihydro-5-(2-(dimethylamino)ethyl)-2-(p-methoxyphenyl)-1,5-benzothiazepine-4(5h)-one ou un de ses sels d'addition d'acides acceptables en pharmacie
TR199801801T2 (xx)	1998-12-21	Madde k�t�ye kullan�m�n�n tedavisi.
FR2786699B1 (fr)	2002-10-04	Medicament destine notamment a prevenir ou traiter les dysfonctions sexuelles
EA199800953A1 (ru)	1999-04-29	Компонент в, используемый в качестве рубцующего агента, содержащая его фармацевтическая композиция и способ лечения
PT1313500E (pt)	2005-02-28	Associacoes de dalfopristina/quinupristina com o cefpirome
EP1106177A4 (en)	2002-03-13	AGENTS FOR INCREASING MEDICINE ACCUMULATION IN TUMOR TISSUES
ES2062752T3 (es)	1994-12-16	Preparado de una sal de oxipurinol en forma oral para el tratamiento de hiperuricemia.
ITMI950625A0 (it)	1995-03-28	Composizione farmaceutica attiva nella cura di affezioni dermatologiche