DK1034000T3 - Fremgangsmåde til fremstilling af vacciner til forebyggelse af de patogene virkninger relateret til en HIV-retrovirusinfektion - Google Patents

Fremgangsmåde til fremstilling af vacciner til forebyggelse af de patogene virkninger relateret til en HIV-retrovirusinfektion

Info

Publication number
DK1034000T3
DK1034000T3 DK98955673T DK98955673T DK1034000T3 DK 1034000 T3 DK1034000 T3 DK 1034000T3 DK 98955673 T DK98955673 T DK 98955673T DK 98955673 T DK98955673 T DK 98955673T DK 1034000 T3 DK1034000 T3 DK 1034000T3
Authority
DK
Denmark
Prior art keywords
prevent
effects related
pathogenic effects
retrovirus infection
preparing vaccines
Prior art date
Application number
DK98955673T
Other languages
English (en)
Inventor
Pierre-Francois Serres
Christophe Geourjon
Gilbert Deleage
Christophe Combet
Original Assignee
Mymetics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mymetics Sa filed Critical Mymetics Sa
Application granted granted Critical
Publication of DK1034000T3 publication Critical patent/DK1034000T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1145—Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/246—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK98955673T 1997-11-17 1998-11-17 Fremgangsmåde til fremstilling af vacciner til forebyggelse af de patogene virkninger relateret til en HIV-retrovirusinfektion DK1034000T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9714387A FR2771011B1 (fr) 1997-11-17 1997-11-17 Obtention de vaccins destines a prevenir les effets pathogenes associes a une infection retrovirale
PCT/FR1998/002447 WO1999025377A1 (fr) 1997-11-17 1998-11-17 Obtention de vaccins destines a prevenir les effets pathogenes associes a une infection retrovirale

Publications (1)

Publication Number Publication Date
DK1034000T3 true DK1034000T3 (da) 2007-06-04

Family

ID=9513450

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98955673T DK1034000T3 (da) 1997-11-17 1998-11-17 Fremgangsmåde til fremstilling af vacciner til forebyggelse af de patogene virkninger relateret til en HIV-retrovirusinfektion

Country Status (19)

Country Link
US (3) US6455265B1 (da)
EP (1) EP1034000B1 (da)
JP (1) JP4837823B2 (da)
KR (1) KR20010032210A (da)
CN (1) CN1281371A (da)
AP (1) AP2000001841A0 (da)
AT (1) ATE353017T1 (da)
AU (1) AU1243499A (da)
BR (1) BR9814204A (da)
CA (1) CA2309676C (da)
DE (1) DE69837012T2 (da)
DK (1) DK1034000T3 (da)
EA (1) EA200000528A1 (da)
ES (1) ES2281938T3 (da)
FR (1) FR2771011B1 (da)
IL (2) IL136163A0 (da)
OA (1) OA11522A (da)
PT (1) PT1034000E (da)
WO (1) WO1999025377A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2771011B1 (fr) * 1997-11-17 2000-01-28 Hippocampe Obtention de vaccins destines a prevenir les effets pathogenes associes a une infection retrovirale
CN1396178A (zh) * 2002-06-17 2003-02-12 成都阳辉生物科技有限责任公司 抗乙肝病毒等包膜病毒感染的工程多肽及其制备方法
EP1466924B9 (en) * 2003-04-11 2013-06-19 Institut Pasteur Synthetic peptide vaccines for HIV: the CBD epitope as an effective immunogen to elicit broadly neutralizing antibodies against HIV
EP1680444A1 (en) 2003-07-30 2006-07-19 Mymetics Corporation New soluble and stabilized trimeric form of gp41 polypeptides
JP2007505320A (ja) * 2003-09-11 2007-03-08 アイデックス ラボラトリーズ インコーポレイテッド ネコ免疫不全ウイルスの検出のための方法と装置
EP1709447B1 (en) * 2003-12-18 2009-06-24 Idexx Laboratories, Inc. Method for detecting feline immunodeficiency virus
AU2005215629B2 (en) * 2004-02-19 2009-01-29 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
ZA200608178B (en) * 2004-03-30 2008-10-29 Roussy Inst Gustave Polypeptide sequence involved in the modulation of the immunosuppresive effect of viral proteins
AU2005267605B2 (en) * 2004-06-30 2009-03-26 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
EP1761555A1 (en) * 2004-06-30 2007-03-14 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
JP4866848B2 (ja) * 2004-06-30 2012-02-01 アイデックス ラボラトリーズ インコーポレイテッド ネコ免疫不全ウイルス（ｆｉｖ）のｅｎｖタンパク質のｖ３領域に由来するペプチドの使用を含むｆｉｖを検出するための方法および装置
US7291338B2 (en) * 2005-03-09 2007-11-06 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
JP5020941B2 (ja) * 2005-05-02 2012-09-05 マイメティクス コーポレーション Ｈｉｖに対して中和活性を有するがｉｌ２には中和活性を有さない抗体又はその断片
TWI343180B (en) * 2005-07-01 2011-06-01 Ind Tech Res Inst The acoustic wave sensing-device integrated with micro channels
WO2007099387A1 (en) * 2006-03-03 2007-09-07 Mymetics Corporation Virosome-like vesicles comprising gp41-derived antigens
CN1869704B (zh) * 2006-06-14 2010-06-30 厦门大学 快速鉴定与病原菌互作的宿主蛋白的方法
US20110195089A1 (en) * 2008-10-08 2011-08-11 The Adminstrators Of The Tulane Educational Fund Compositions, methods, and kits for enhancing the immunogenicity of pathogenic antigens
BRPI1008671A2 (pt) 2009-02-06 2016-03-08 Mymetics Corp polipeptídeo modificado, composição aquosa, conjugado, polinucleotídeo, trímero, vetor de expressão, célula hospedeira, composição antigênica ou imunogênica, preparação farmacêutica, uso de pelo menos um polipeptídeo, e método de tratamento e/ou profilaxia contra uma infecção por iv.
US8652459B2 (en) 2009-02-06 2014-02-18 Mymetics Corporation Splitting GP41
CA2769407A1 (en) * 2009-08-21 2011-02-24 Dana-Farber Cancer Institute, Inc. Mimotopes of hiv and uses thereof
US8809004B2 (en) 2010-04-02 2014-08-19 Idexx Laboratories, Inc. Detection of feline immunodeficiency virus
CA2832109C (en) 2011-06-10 2021-07-06 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
NZ706288A (en) 2012-08-30 2016-06-24 Merial Inc Expression of chimeric ksac protein and method of producing soluble proteins by high pressure
US20220065857A1 (en) * 2018-12-12 2022-03-03 The Johns Hopkins University Hiv serosignatures for cross-sectional incidence estimation
WO2021185851A1 (en) 2020-03-17 2021-09-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Vaccine compositions for hiv prevention and treatment
CN111701016A (zh) * 2020-06-28 2020-09-25 张全志 逆转录病毒原病毒序列在逆转录病毒疫苗设计中的应用
CN118515733B (zh) * 2023-02-20 2025-11-18 菲鹏生物股份有限公司 Hiv蛋白及其在检测hiv抗体中的应用
CN118561966B (zh) * 2024-05-20 2025-07-11 浙江大学 人内源性逆转录病毒包膜蛋白突变体、截短体及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993001304A1 (en) * 1991-07-10 1993-01-21 Synbiotics Corporation Synthetic peptides related to fiv-env proteins
JP4010560B2 (ja) * 1992-07-20 2007-11-21 ドューク ユニバーシティー Ｈｉｖ複製を阻害する化合物
GB9219936D0 (en) * 1992-09-21 1992-11-04 Pitman Moore Inc Vaccines
US6017536A (en) * 1993-06-07 2000-01-25 Trimeris, Inc. Simian immunodeficiency virus peptides with antifusogenic and antiviral activities
US6479055B1 (en) * 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
FR2771011B1 (fr) * 1997-11-17 2000-01-28 Hippocampe Obtention de vaccins destines a prevenir les effets pathogenes associes a une infection retrovirale

Also Published As

Publication number Publication date
US6455265B1 (en) 2002-09-24
EA200000528A1 (ru) 2001-02-26
US7829683B2 (en) 2010-11-09
DE69837012D1 (de) 2007-03-22
JP4837823B2 (ja) 2011-12-14
JP2001524456A (ja) 2001-12-04
US7253270B2 (en) 2007-08-07
WO1999025377A1 (fr) 1999-05-27
AU1243499A (en) 1999-06-07
FR2771011B1 (fr) 2000-01-28
US20050048478A9 (en) 2005-03-03
CA2309676C (fr) 2012-08-07
US20040014046A1 (en) 2004-01-22
CA2309676A1 (fr) 1999-05-27
ES2281938T3 (es) 2007-10-01
KR20010032210A (ko) 2001-04-16
AP2000001841A0 (en) 2000-06-30
IL136163A0 (en) 2001-05-20
ATE353017T1 (de) 2007-02-15
FR2771011A1 (fr) 1999-05-21
US20080003229A1 (en) 2008-01-03
CN1281371A (zh) 2001-01-24
IL136163A (en) 2007-07-04
EP1034000A1 (fr) 2000-09-13
PT1034000E (pt) 2007-05-31
DE69837012T2 (de) 2007-11-29
BR9814204A (pt) 2000-10-03
OA11522A (fr) 2004-02-09
EP1034000B1 (fr) 2007-01-31

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