DK103680A - Fremgangsmaade til fremstilling af n-(6-( (acylamjnoacylamino eller aminoacylamino)phenyl)-1,2-dihydro-2-oxonicotinyl) penicillinforbindelser - Google Patents

Fremgangsmaade til fremstilling af n-(6-( (acylamjnoacylamino eller aminoacylamino)phenyl)-1,2-dihydro-2-oxonicotinyl) penicillinforbindelser

Info

Publication number
DK103680A
DK103680A DK103680A DK103680A DK103680A DK 103680 A DK103680 A DK 103680A DK 103680 A DK103680 A DK 103680A DK 103680 A DK103680 A DK 103680A DK 103680 A DK103680 A DK 103680A
Authority
DK
Denmark
Prior art keywords
acylaminoacylamino
oxonicotinyl
aminoacylamino
dihydro
phenyl
Prior art date
Application number
DK103680A
Other languages
English (en)
Inventor
T H Haskell
E D Nicolaides
G G Huang
M P Hutt
P W K Woo
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK103680A publication Critical patent/DK103680A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK103680A 1979-03-12 1980-03-11 Fremgangsmaade til fremstilling af n-(6-( (acylamjnoacylamino eller aminoacylamino)phenyl)-1,2-dihydro-2-oxonicotinyl) penicillinforbindelser DK103680A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2000079A 1979-03-12 1979-03-12
US06/112,657 US4278681A (en) 1979-03-12 1980-01-31 Antibacterial amide compounds and means for using the same

Publications (1)

Publication Number Publication Date
DK103680A true DK103680A (da) 1980-09-13

Family

ID=26692870

Family Applications (1)

Application Number Title Priority Date Filing Date
DK103680A DK103680A (da) 1979-03-12 1980-03-11 Fremgangsmaade til fremstilling af n-(6-( (acylamjnoacylamino eller aminoacylamino)phenyl)-1,2-dihydro-2-oxonicotinyl) penicillinforbindelser

Country Status (7)

Country Link
US (1) US4278681A (da)
EP (1) EP0015773B1 (da)
AU (1) AU541984B2 (da)
CA (1) CA1144158A (da)
DE (1) DE3064190D1 (da)
DK (1) DK103680A (da)
ES (2) ES8105007A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4382089A (en) * 1982-03-02 1983-05-03 Warner-Lambert Company Antibacterial amide compounds, compositions thereof and methods of using them
US7018988B2 (en) * 2000-03-27 2006-03-28 Applied Research Systems Ars Holding N.V. Pharmaceutically active pyrrolidine derivatives as Bax inhibitors
US7018642B2 (en) * 2001-04-27 2006-03-28 The Procter & Gamble Company Compounds, compositions, and methods for controlling biofilms
WO2016039939A1 (en) * 2014-09-09 2016-03-17 Ptc Therapeutics, Inc. Bicyclic and tricyclic substituted 2-pyridinone antibacterial compounds
WO2016039937A1 (en) * 2014-09-09 2016-03-17 Ptc Therapeutics, Inc. Bicyclic and tricyclic substituted 2-pyridinone antibacterial compounds
EP3787612A4 (en) 2018-05-04 2021-11-17 Remedy Plan, Inc. CANCER TREATMENTS AGAINST CANCER STEM CELLS
PH12022551081A1 (en) 2019-11-06 2024-06-19 Remedy Plan Inc Cancer treatments targeting cancer stem cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3873523A (en) * 1972-12-15 1975-03-25 Parke Davis & Co Derivatives of ampicillin
US3954734A (en) * 1974-01-21 1976-05-04 Parke, Davis & Company Novel antibacterial amide compounds and process means for producing the same
US4053470A (en) * 1974-12-23 1977-10-11 Parke, Davis & Company Substituted-1,2-dihydro-2-oxonicotinyl-cephalosporins
US4092309A (en) * 1977-04-27 1978-05-30 Warner-Lambert Company Derivatives of amoxicillin

Also Published As

Publication number Publication date
AU541984B2 (en) 1985-01-31
EP0015773A2 (en) 1980-09-17
EP0015773B1 (en) 1983-07-20
DE3064190D1 (en) 1983-08-25
ES489401A0 (es) 1981-05-16
ES8200687A1 (es) 1981-11-01
EP0015773A3 (en) 1980-11-26
ES8105007A1 (es) 1981-05-16
ES496567A0 (es) 1981-11-01
US4278681A (en) 1981-07-14
AU5634280A (en) 1980-09-18
CA1144158A (en) 1983-04-05

Similar Documents

Publication Publication Date Title
DK51280A (da) Fremgangsmaade til fremstilling af 1-( (acyltio)-eller (merkapto)-1-oxoalkyl)-1,2,3,4-tetrahydrokinolin-2-karbolxyrer
DK357181A (da) R fremgangsmaade til fremstilling af heterocycliske forbindelse
DK466681A (da) Analogifremgangmaade til fremstilling af benzo-kondenserede heterocycliske forbindelser
DK157019C (da) Analogifremgangsmaade til fremstilling af 2-amino-4-hydroxyquinazolinderivater
DK331881A (da) Fremgangsmaade til fremstilling af trisubstituerede imidazolderivater eller salte deraf
DK152125C (da) Analogifremgangsmaade til fremstilling af 1-(3'-trifluormethyl-4'-nitrophenyl)-4,4-dimethylimidazolidin-2,5-dion
DK159390C (da) Analogifremgangsmaade til fremstilling af 3-(1-piperidinylalkyl)-4h-pyridooe1,2-aaapyrimidin-4-on-derivater
DK357081A (da) Fremgangsmaade til fremstilling af heterocycliske forbindelser
DK151252C (da) Analogifremgangsmaade til fremstilling af 3-alkyltio-4-oxoquinolinforbindelser
DK357281A (da) R fremgangsmaade til fremstilling af heterocycliske forbindelse
DK447380A (da) Fremgangsmaade til fremstilling af d3-vitaminforbindelser
DK446980A (da) R fremgangsmaade til fremstilling af heterocycliske forbindelse
DK388079A (da) R fremgangsmaade til fremstilling af heterocycliske forbindelse
DK289580A (da) Fremgangsmaade til fremstilling af heterocycliske phenoxyaminer
DK90681A (da) R fremgangsmaade til fremstilling af heterocycliske forbindelse
DK89480A (da) R fremgangsmaade til fremstilling af heterocycliske forbindelse
DK161310C (da) Analogifremgangsmaade til fremstilling af aminopropoxyphenylderivater
DK150479C (da) Fremgangsmaade til fremstilling af 2-chlor-5-trifluormethylpyridin
DK420480A (da) R fremgangsmaade til fremstilling af heterocycliske forbindelse
DK103780A (da) Fremgangsmaade til fremstilling af n-(6- ( (acylaminoacylamino eller aminoacylamino)phenyl)-1,2-dihydro-2-oxonicotinyl) cephalosporinforbindelser
DK154136C (da) Analogifremgangsmaade til fremstilling af 2-amino-3-benzoylphenylacetamider
DK344180A (da) R fremgangsmaade til fremstilling af heterocycliske forbindelse
DK355180A (da) Fremgangsmaade til fremstilling af heterocycliske forbindelser
DK152674C (da) Analogifremgangsmaade til fremstilling af 3-metyltiometyl-4-oxo-quinolonderivater
DK146390C (da) Analogifremgangsmaade til fremstilling af 25-halogen-cholest-5-en-3beta,22-dioler eller estere deraf

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment