DK1040202T3 - DNA-polymorfiidentitetsbestemmelse under anvendelse af flowcytometri - Google Patents
DNA-polymorfiidentitetsbestemmelse under anvendelse af flowcytometriInfo
- Publication number
- DK1040202T3 DK1040202T3 DK98955222T DK98955222T DK1040202T3 DK 1040202 T3 DK1040202 T3 DK 1040202T3 DK 98955222 T DK98955222 T DK 98955222T DK 98955222 T DK98955222 T DK 98955222T DK 1040202 T3 DK1040202 T3 DK 1040202T3
- Authority
- DK
- Denmark
- Prior art keywords
- flow cytometry
- dna
- identity determination
- dna polymorphism
- immobilized
- Prior art date
Links
- 238000000684 flow cytometry Methods 0.000 title abstract 3
- 108020004414 DNA Proteins 0.000 abstract 3
- 102000053602 DNA Human genes 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- 239000005546 dideoxynucleotide Substances 0.000 abstract 2
- 102000012410 DNA Ligases Human genes 0.000 abstract 1
- 108010061982 DNA Ligases Proteins 0.000 abstract 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 238000011835 investigation Methods 0.000 abstract 1
- 239000004005 microsphere Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6862—Ligase chain reaction [LCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6368597P | 1997-10-28 | 1997-10-28 | |
| PCT/US1998/023143 WO1999022030A1 (fr) | 1997-10-28 | 1998-10-28 | Identification du polymorphisme adn par la cytometrie de flux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1040202T3 true DK1040202T3 (da) | 2009-04-14 |
Family
ID=22050818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98955222T DK1040202T3 (da) | 1997-10-28 | 1998-10-28 | DNA-polymorfiidentitetsbestemmelse under anvendelse af flowcytometri |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6287766B1 (fr) |
| EP (3) | EP1032701A1 (fr) |
| JP (3) | JP2003502005A (fr) |
| AT (1) | ATE419382T1 (fr) |
| AU (2) | AU754849B2 (fr) |
| CA (2) | CA2306907A1 (fr) |
| DE (1) | DE69840416D1 (fr) |
| DK (1) | DK1040202T3 (fr) |
| ES (1) | ES2320604T3 (fr) |
| IL (2) | IL135852A0 (fr) |
| IS (2) | IS2699B (fr) |
| PT (1) | PT1040202E (fr) |
| WO (2) | WO1999022029A1 (fr) |
Families Citing this family (72)
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|---|---|---|---|---|
| WO1999022029A1 (fr) * | 1997-10-28 | 1999-05-06 | The Regents Of The University Of California | Detection de mesappariements de bases d'adn par cytometrie de flux |
| EP1036332B1 (fr) * | 1997-12-04 | 2005-07-13 | Amersham Biosciences UK Limited | Procede pour dosages multiples |
| WO2000056925A2 (fr) * | 1999-03-19 | 2000-09-28 | Aclara Biosciences, Inc. | Techniques de detection de polymorphismes nucleotidiques uniques |
| JP3668075B2 (ja) | 1999-10-12 | 2005-07-06 | 光夫 板倉 | 遺伝物質シーケンス決定用懸濁系、その懸濁系を用いた遺伝物質シーケンス決定方法およびその懸濁系を用いたＳＮＰｓ高速スコアリング方法 |
| DE19958980A1 (de) * | 1999-11-18 | 2001-09-27 | Wolfgang Goehde | Verfahren zur Bestimmung von PCR-Produkten, sowie ein PCR-Detektions-Kit und eine Vorrichtung für ein solches Verfahren |
| JP2003521252A (ja) * | 2000-02-07 | 2003-07-15 | イルミナ インコーポレイテッド | ユニバーサルプライミングを用いる核酸検出方法 |
| US6365355B1 (en) | 2000-03-28 | 2002-04-02 | The Regents Of The University Of California | Chimeric proteins for detection and quantitation of DNA mutations, DNA sequence variations, DNA damage and DNA mismatches |
| US6340566B1 (en) * | 2000-03-28 | 2002-01-22 | The Regents Of The University Of California | Detection and quantitation of single nucleotide polymorphisms, DNA sequence variations, DNA mutations, DNA damage and DNA mismatches |
| AU7125401A (en) * | 2000-05-19 | 2001-12-03 | David J Marshall | Materials and methods for detection of nucleic acids |
| CA2389310A1 (fr) * | 2000-08-30 | 2002-03-07 | Sanko Junyaku Co., Ltd. | Procede de detection de gene |
| US7465540B2 (en) * | 2000-09-21 | 2008-12-16 | Luminex Corporation | Multiple reporter read-out for bioassays |
| DE60137649D1 (de) * | 2000-10-14 | 2009-03-26 | Eragen Biosciences Inc | Nachweissysteme auf festen trägern und methoden zur verwendung von nicht-standardbasen |
| US6592713B2 (en) | 2000-12-18 | 2003-07-15 | Sca Hygiene Products Ab | Method of producing a nonwoven material |
| US7083951B2 (en) * | 2001-02-14 | 2006-08-01 | The Regents Of The University Of California | Flow cytometric detection method for DNA samples |
| US20020115116A1 (en) * | 2001-02-22 | 2002-08-22 | Yong Song | Multiplex protein interaction determinations using glutathione-GST binding |
| US7153656B2 (en) * | 2001-09-11 | 2006-12-26 | Los Alamos National Security, Llc | Nucleic acid sequence detection using multiplexed oligonucleotide PCR |
| ES2712173T3 (es) | 2001-10-15 | 2019-05-09 | Bioarray Solutions Ltd | Análisis multiplexado de loci polimórficos mediante consulta simultánea y detección mediada por enzimas |
| AU2002366179A1 (en) * | 2001-11-20 | 2003-06-10 | The Regents Of The University Of California | Early leukemia diagnostics using microsphere arrays |
| AU2002357249A1 (en) * | 2001-12-13 | 2003-07-09 | Blue Heron Biotechnology, Inc. | Methods for removal of double-stranded oligonucleotides containing sequence errors using mismatch recognition proteins |
| WO2003078587A2 (fr) | 2002-03-13 | 2003-09-25 | Syngenta Participations, Ag. | Procede de detection des acides nucleiques |
| US7304128B2 (en) * | 2002-06-04 | 2007-12-04 | E.I. Du Pont De Nemours And Company | Carbon nanotube binding peptides |
| DE60335116D1 (de) * | 2002-06-28 | 2011-01-05 | Primeradx Inc | Verfahren zum nachweis von sequenzunterschieden |
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| EP2390352A1 (fr) | 2003-03-18 | 2011-11-30 | Quantum Genetics Ireland Limited | Systemes et procedes pour accroitre la production de proteines et de lait chez des bovins laitiers |
| WO2004090153A2 (fr) * | 2003-04-01 | 2004-10-21 | Eragen Biosciences,Inc. | Inhibiteur de polymerase et son procede d'utilisation |
| WO2004090170A1 (fr) * | 2003-04-02 | 2004-10-21 | Blue Heron Biotechnology, Inc. | Reduction d'erreur en genematique |
| US8637650B2 (en) | 2003-11-05 | 2014-01-28 | Genovoxx Gmbh | Macromolecular nucleotide compounds and methods for using the same |
| CA2556911C (fr) | 2004-02-19 | 2013-07-30 | The Governors Of The University Of Alberta | Polymorphismes du promoteur de la leptine et utilisations correspondantes |
| DE102005008583B4 (de) * | 2005-02-24 | 2007-10-25 | Johannes-Gutenberg-Universität Mainz | Verfahren zur Typisierung eines Individuums mittels short tandem repeat (STR)-Loci der genomischen DNA |
| JP4399575B2 (ja) * | 2005-03-31 | 2010-01-20 | 独立行政法人産業技術総合研究所 | 遺伝子断片中のヌクレオチドの種類の特定方法 |
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| EP1953241A1 (fr) * | 2005-11-29 | 2008-08-06 | Olympus Corporation | Méthode d'analyse de modifications de la structure primaire d'un acide nucléique |
| US7960116B2 (en) * | 2007-09-28 | 2011-06-14 | Pacific Biosciences Of California, Inc. | Nucleic acid sequencing methods and systems |
| US8871687B2 (en) * | 2007-09-28 | 2014-10-28 | Quest Diagnostics Investments Incorporated | Nucleic acid sequencing by single-base primer extension |
| US8093063B2 (en) | 2007-11-29 | 2012-01-10 | Quest Diagnostics Investments Incorporated | Assay for detecting genetic abnormalities in genomic nucleic acids |
| CN101445832B (zh) * | 2008-12-23 | 2011-09-14 | 广州益善生物技术有限公司 | Pik3ca基因突变的检测探针、液相芯片及其检测方法 |
| CN101487051B (zh) * | 2009-02-24 | 2011-07-20 | 广州益善生物技术有限公司 | Braf基因突变的检测探针、液相芯片及其检测方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4770992A (en) * | 1985-11-27 | 1988-09-13 | Den Engh Gerrit J Van | Detection of specific DNA sequences by flow cytometry |
| US4962037A (en) * | 1987-10-07 | 1990-10-09 | United States Of America | Method for rapid base sequencing in DNA and RNA |
| US4988617A (en) * | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
| US5512439A (en) * | 1988-11-21 | 1996-04-30 | Dynal As | Oligonucleotide-linked magnetic particles and uses thereof |
| US5629158A (en) * | 1989-03-22 | 1997-05-13 | Cemu Bitecknik Ab | Solid phase diagnosis of medical conditions |
| US5437976A (en) * | 1991-08-08 | 1995-08-01 | Arizona Board Of Regents, The University Of Arizona | Multi-domain DNA ligands bound to a solid matrix for protein and nucleic acid affinity chromatography and processing of solid-phase DNA |
| AU3919293A (en) * | 1992-03-27 | 1993-11-08 | University Of Maryland At Baltimore | Detection of gene mutations with mismatch repair enzymes |
| EP0705905B1 (fr) * | 1994-07-16 | 2001-10-10 | Roche Diagnostics GmbH | Procédé pour la détection sensible d'acides nucléiques |
| US5681702A (en) * | 1994-08-30 | 1997-10-28 | Chiron Corporation | Reduction of nonspecific hybridization by using novel base-pairing schemes |
| WO1996015271A1 (fr) * | 1994-11-16 | 1996-05-23 | Abbott Laboratories | Amplification multiplex dependant des ligatures |
| ATE496288T1 (de) * | 1995-10-11 | 2011-02-15 | Luminex Corp | Gleichzeitige mehrfachanalyse klinischer proben |
| US5736330A (en) * | 1995-10-11 | 1998-04-07 | Luminex Corporation | Method and compositions for flow cytometric determination of DNA sequences |
| ES2220997T3 (es) * | 1995-12-22 | 2004-12-16 | Exact Sciences Corporation | Metodos para la deteccion de poblaciones clonales de celulas transformadas en una muestra celular genomicamente heterogenea. |
| US5670325A (en) * | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
| DE69739357D1 (de) * | 1996-06-04 | 2009-05-28 | Univ Utah Res Found | Überwachung der hybridisierung während pcr |
| AU8162498A (en) * | 1997-06-25 | 1999-01-04 | Orchid Biosciences, Inc. | Methods for the detection of multiple single nucleotide polymorphisms in a single reaction |
| WO1999022029A1 (fr) * | 1997-10-28 | 1999-05-06 | The Regents Of The University Of California | Detection de mesappariements de bases d'adn par cytometrie de flux |
| WO1999067414A1 (fr) | 1998-06-24 | 1999-12-29 | Glaxo Group Limited | Procede de detection de nucleotide |
-
1998
- 1998-10-28 WO PCT/US1998/023142 patent/WO1999022029A1/fr not_active Ceased
- 1998-10-28 JP JP2000518118A patent/JP2003502005A/ja active Pending
- 1998-10-28 AU AU12078/99A patent/AU754849B2/en not_active Ceased
- 1998-10-28 IL IL13585298A patent/IL135852A0/xx unknown
- 1998-10-28 IL IL13585198A patent/IL135851A/en not_active IP Right Cessation
- 1998-10-28 WO PCT/US1998/023143 patent/WO1999022030A1/fr not_active Ceased
- 1998-10-28 AT AT98955222T patent/ATE419382T1/de active
- 1998-10-28 ES ES98955222T patent/ES2320604T3/es not_active Expired - Lifetime
- 1998-10-28 EP EP98955221A patent/EP1032701A1/fr not_active Withdrawn
- 1998-10-28 CA CA002306907A patent/CA2306907A1/fr not_active Abandoned
- 1998-10-28 AU AU12077/99A patent/AU1207799A/en not_active Abandoned
- 1998-10-28 DK DK98955222T patent/DK1040202T3/da active
- 1998-10-28 CA CA2308599A patent/CA2308599C/fr not_active Expired - Fee Related
- 1998-10-28 JP JP2000518119A patent/JP4502502B2/ja not_active Expired - Fee Related
- 1998-10-28 US US09/182,869 patent/US6287766B1/en not_active Expired - Lifetime
- 1998-10-28 EP EP98955222A patent/EP1040202B9/fr not_active Expired - Lifetime
- 1998-10-28 PT PT98955222T patent/PT1040202E/pt unknown
- 1998-10-28 DE DE69840416T patent/DE69840416D1/de not_active Expired - Lifetime
- 1998-10-28 EP EP08104631A patent/EP2034031A1/fr not_active Withdrawn
-
2000
- 2000-04-14 IS IS5454A patent/IS2699B/is unknown
- 2000-04-14 IS IS5455A patent/IS5455A/is unknown
-
2001
- 2001-09-11 US US09/953,534 patent/US20020015962A1/en not_active Abandoned
-
2009
- 2009-12-22 JP JP2009291170A patent/JP2010088454A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP4502502B2 (ja) | 2010-07-14 |
| IL135851A (en) | 2004-03-28 |
| CA2308599C (fr) | 2012-05-22 |
| EP1040202B9 (fr) | 2009-09-23 |
| IS5455A (is) | 2000-04-14 |
| IL135851A0 (en) | 2001-05-20 |
| PT1040202E (pt) | 2009-03-26 |
| WO1999022030A1 (fr) | 1999-05-06 |
| JP2003502005A (ja) | 2003-01-21 |
| JP2001520895A (ja) | 2001-11-06 |
| IS5454A (is) | 2000-04-14 |
| ATE419382T1 (de) | 2009-01-15 |
| ES2320604T3 (es) | 2009-05-25 |
| EP1032701A1 (fr) | 2000-09-06 |
| AU1207899A (en) | 1999-05-17 |
| CA2306907A1 (fr) | 1999-05-06 |
| WO1999022029A1 (fr) | 1999-05-06 |
| US20020015962A1 (en) | 2002-02-07 |
| EP1040202B1 (fr) | 2008-12-31 |
| US6287766B1 (en) | 2001-09-11 |
| EP1040202A1 (fr) | 2000-10-04 |
| AU754849B2 (en) | 2002-11-28 |
| JP2010088454A (ja) | 2010-04-22 |
| IS2699B (is) | 2010-11-15 |
| IL135852A0 (en) | 2001-05-20 |
| CA2308599A1 (fr) | 1999-05-06 |
| AU1207799A (en) | 1999-05-17 |
| DE69840416D1 (de) | 2009-02-12 |
| EP1040202A4 (fr) | 2004-08-18 |
| EP2034031A1 (fr) | 2009-03-11 |
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