DK1043317T3 - Pyridazinderivater og medikamenter indeholdende dem som aktiv bestanddel - Google Patents

Pyridazinderivater og medikamenter indeholdende dem som aktiv bestanddel

Info

Publication number: DK1043317T3
Authority: DK; Denmark
Prior art keywords: group; alkoxyl; active ingredient; drugs containing; pyridazine derivatives
Prior art date: 1997-11-19

Application number

DK98951732T

Other languages

English (en)

Inventor

Masao Ohkuchi

Yoshinori Kyotani

Hiromichi Shigyo

Tomoyuki Koshi

Takayuki Matsuda

Hideo Yoshizaki

Takahiro Kitamura

Tadaaki Ohgiya

Yukiyoshi Yamazaki

Kyoko Kotaki

Yuriko Habata

Natsuyo Kumai

Original Assignee

Kowa Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-19

Filing date

1998-11-09

Publication date

2009-07-06

1997-11-19 Priority claimed from JP31813397A external-priority patent/JP3999861B2/ja

1998-11-09 Application filed by Kowa Co filed Critical Kowa Co

2009-07-06 Application granted granted Critical

2009-07-06 Publication of DK1043317T3 publication Critical patent/DK1043317T3/da

Links

150000004892 pyridazines Chemical class 0.000 title abstract 2
239000004480 active ingredient Substances 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
125000003545 alkoxy group Chemical group 0.000 abstract 4
125000001424 substituent group Chemical group 0.000 abstract 3
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 abstract 2
125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 2
125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
125000004450 alkenylene group Chemical group 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
125000004434 sulfur atom Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/18—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK98951732T 1997-11-19 1998-11-09 Pyridazinderivater og medikamenter indeholdende dem som aktiv bestanddel DK1043317T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP31813297		1997-11-19
JP31813397A JP3999861B2 (ja)	1997-11-19	1997-11-19	新規ピリダジン誘導体及びこれを有効成分とする医薬
PCT/JP1998/005023 WO1999025697A1 (en)	1997-11-19	1998-11-09	Novel pyridazine derivatives and drugs containing the same as the active ingredient

Publications (1)

Publication Number	Publication Date
DK1043317T3 true DK1043317T3 (da)	2009-07-06

Family

ID=26569260

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98951732T DK1043317T3 (da)	1997-11-19	1998-11-09	Pyridazinderivater og medikamenter indeholdende dem som aktiv bestanddel

Country Status (20)

Country	Link
US (11)	US6348468B1 (da)
EP (2)	EP1043317B1 (da)
KR (1)	KR100626605B1 (da)
CN (1)	CN1142148C (da)
AT (1)	ATE428700T1 (da)
AU (1)	AU738595B2 (da)
BR (1)	BR9813998A (da)
CA (1)	CA2307111C (da)
DE (1)	DE69840755D1 (da)
DK (1)	DK1043317T3 (da)
ES (1)	ES2324126T3 (da)
HU (1)	HUP0100059A3 (da)
ID (1)	ID24166A (da)
MX (1)	MXPA00004955A (da)
NO (1)	NO316021B1 (da)
NZ (1)	NZ504045A (da)
PT (1)	PT1043317E (da)
RU (1)	RU2209813C2 (da)
TW (1)	TW502025B (da)
WO (1)	WO1999025697A1 (da)

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DE102005057924A1 (de) *	2005-12-05	2007-06-06	Merck Patent Gmbh	Pyridazinonderivate
US20090203701A1 (en) *	2006-06-29	2009-08-13	Kowa Co., Ltd	Prophylactic and/or therapeutic agent for rheumatoid arthritis
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TW200838535A (en)	2007-01-29	2008-10-01	Kowa Co	Therapeutic agent for multiple sclerosis
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ES2550667T3 (es)	2010-02-18	2015-11-11	Vtv Therapeutics Llc	Derivados de fenilheteroarilo y métodos de uso de los mismos
WO2013097052A1 (en)	2011-12-30	2013-07-04	Abbott Laboratories	Bromodomain inhibitors
CN102603676B (zh) *	2012-02-20	2014-02-12	徐江平	一种能避免呕吐反应的磷酸二酯酶4抑制剂
CA3018802A1 (en)	2016-04-15	2017-10-19	Abbvie Inc.	Bromodomain inhibitors
AU2017348186A1 (en) *	2016-10-26	2019-05-16	Proteostasis Therapeutics, Inc	Pyridazine derivatives, compositions and methods for modulating CFTR
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PT1005460E (pt)	1997-08-22	2006-07-31	Abbott Lab	Biossintese de inibidores de prostaglandina-endoperoxido h-sintase
CN1142148C (zh) *	1997-11-19	2004-03-17	兴和株式会社	新颖的哒嗪衍生物和含有其作为有效成分的药物
TWI241295B (en) *	1998-03-02	2005-10-11	Kowa Co	Pyridazine derivative and medicine containing the same as effect component
JP2000247959A (ja) *	1999-02-26	2000-09-12	Kowa Co	ピリダジン−３−オン誘導体及びこれを含有する医薬
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1998
- 1998-11-09 CN CNB988113015A patent/CN1142148C/zh not_active Expired - Fee Related
- 1998-11-09 PT PT98951732T patent/PT1043317E/pt unknown
- 1998-11-09 WO PCT/JP1998/005023 patent/WO1999025697A1/ja not_active Ceased
- 1998-11-09 BR BR9813998-3A patent/BR9813998A/pt active Search and Examination
- 1998-11-09 US US09/530,949 patent/US6348468B1/en not_active Expired - Fee Related
- 1998-11-09 AU AU97626/98A patent/AU738595B2/en not_active Ceased
- 1998-11-09 CA CA002307111A patent/CA2307111C/en not_active Expired - Fee Related
- 1998-11-09 ID IDW20000931A patent/ID24166A/id unknown
- 1998-11-09 RU RU2000115577/04A patent/RU2209813C2/ru not_active IP Right Cessation
- 1998-11-09 AT AT98951732T patent/ATE428700T1/de not_active IP Right Cessation
- 1998-11-09 EP EP98951732A patent/EP1043317B1/en not_active Expired - Lifetime
- 1998-11-09 EP EP08019558A patent/EP2017266A1/en not_active Withdrawn
- 1998-11-09 KR KR1020007004967A patent/KR100626605B1/ko not_active Expired - Fee Related
- 1998-11-09 NZ NZ504045A patent/NZ504045A/en unknown
- 1998-11-09 DK DK98951732T patent/DK1043317T3/da active
- 1998-11-09 HU HU0100059A patent/HUP0100059A3/hu unknown
- 1998-11-09 ES ES98951732T patent/ES2324126T3/es not_active Expired - Lifetime
- 1998-11-09 DE DE69840755T patent/DE69840755D1/de not_active Expired - Lifetime
- 1998-11-09 MX MXPA00004955A patent/MXPA00004955A/es not_active IP Right Cessation
- 1998-11-17 TW TW087119032A patent/TW502025B/zh not_active IP Right Cessation
2000
- 2000-04-27 NO NO20002169A patent/NO316021B1/no not_active IP Right Cessation
2001
- 2001-11-30 US US09/996,804 patent/US20020123496A1/en not_active Abandoned
2004
- 2004-01-15 US US10/757,525 patent/US20040147516A1/en not_active Abandoned
- 2004-11-12 US US10/986,350 patent/US20050065155A1/en not_active Abandoned
2005
- 2005-08-15 US US11/203,174 patent/US20050267113A1/en not_active Abandoned
2006
- 2006-03-22 US US11/385,995 patent/US20060160804A1/en not_active Abandoned
- 2006-11-01 US US11/590,811 patent/US20070049595A1/en not_active Abandoned
2007
- 2007-04-30 US US11/741,947 patent/US20070208025A1/en not_active Abandoned
2008
- 2008-01-14 US US12/013,691 patent/US20080119474A1/en not_active Abandoned
- 2008-11-03 US US12/263,816 patent/US20090069332A1/en not_active Abandoned
2009
- 2009-07-06 US US12/497,797 patent/US20090270399A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN1279672A (zh)	2001-01-10
EP1043317B1 (en)	2009-04-15
US20070208025A1 (en)	2007-09-06
KR20010031880A (ko)	2001-04-16
AU9762698A (en)	1999-06-07
US20080119474A1 (en)	2008-05-22
CN1142148C (zh)	2004-03-17
ES2324126T3 (es)	2009-07-30
US20070049595A1 (en)	2007-03-01
CA2307111C (en)	2009-06-30
WO1999025697A1 (en)	1999-05-27
US20090069332A1 (en)	2009-03-12
EP1043317A4 (en)	2003-03-05
PT1043317E (pt)	2009-05-11
US20050267113A1 (en)	2005-12-01
NO20002169L (no)	2000-05-18
BR9813998A (pt)	2000-09-26
TW502025B (en)	2002-09-11
HUP0100059A2 (hu)	2002-02-28
NZ504045A (en)	2001-06-29
MXPA00004955A (es)	2002-10-17
DE69840755D1 (de)	2009-05-28
HK1032969A1 (en)	2001-08-10
AU738595B2 (en)	2001-09-20
US20020123496A1 (en)	2002-09-05
US20090270399A1 (en)	2009-10-29
KR100626605B1 (ko)	2006-09-22
US20050065155A1 (en)	2005-03-24
ID24166A (id)	2000-07-13
RU2209813C2 (ru)	2003-08-10
ATE428700T1 (de)	2009-05-15
NO316021B1 (no)	2003-12-01
US6348468B1 (en)	2002-02-19
NO20002169D0 (no)	2000-04-27
CA2307111A1 (en)	1999-05-27
HUP0100059A3 (en)	2002-08-28
US20040147516A1 (en)	2004-07-29
US20060160804A1 (en)	2006-07-20
EP2017266A1 (en)	2009-01-21
EP1043317A1 (en)	2000-10-11

Publication	Publication Date	Title
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