NO20002169D0 - Nye pyridazinderivater og medikamenter inneholdende disse som effektive ingredienser - Google Patents

Nye pyridazinderivater og medikamenter inneholdende disse som effektive ingredienser

Info

Publication number: NO20002169D0
Authority: NO; Norway
Prior art keywords: group; alkoxyl; effective ingredients; drugs containing; pyridazine derivatives
Prior art date: 1997-11-19

Application number

NO20002169A

Other languages

English (en)

Other versions

NO20002169L (no

NO316021B1 (no

Inventor

Masao Ohkuchi

Yoshinori Kyotani

Hiromichi Shigyo

Tomoyuki Koshi

Takahiro Kitamura

Tadaaki Ohgiya

Takayuki Matsuda

Yukiyoshi Yamazaki

Natsuyo Kumai

Kyoko Kotaki

Hideo Yoshizaki

Yuriko Habata

Original Assignee

Kowa Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-19

Filing date

2000-04-27

Publication date

2000-04-27

1997-11-19 Priority claimed from JP31813397A external-priority patent/JP3999861B2/ja

2000-04-27 Application filed by Kowa Co filed Critical Kowa Co

2000-04-27 Publication of NO20002169D0 publication Critical patent/NO20002169D0/no

2000-05-18 Publication of NO20002169L publication Critical patent/NO20002169L/no

2003-12-01 Publication of NO316021B1 publication Critical patent/NO316021B1/no

Links

150000004892 pyridazines Chemical class 0.000 title abstract 2
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
239000004615 ingredient Substances 0.000 title 1
125000003545 alkoxy group Chemical group 0.000 abstract 4
125000001424 substituent group Chemical group 0.000 abstract 3
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 abstract 2
125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 2
125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
125000004450 alkenylene group Chemical group 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
125000004434 sulfur atom Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/18—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20002169A 1997-11-19 2000-04-27 Nye pyridazinderivater, anveldelse derav og medikamenter inneholdende dissesom effektive ingredienser NO316021B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP31813297		1997-11-19
JP31813397A JP3999861B2 (ja)	1997-11-19	1997-11-19	新規ピリダジン誘導体及びこれを有効成分とする医薬
PCT/JP1998/005023 WO1999025697A1 (en)	1997-11-19	1998-11-09	Novel pyridazine derivatives and drugs containing the same as the active ingredient

Publications (3)

Publication Number	Publication Date
NO20002169D0 true NO20002169D0 (no)	2000-04-27
NO20002169L NO20002169L (no)	2000-05-18
NO316021B1 NO316021B1 (no)	2003-12-01

Family

ID=26569260

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20002169A NO316021B1 (no)	1997-11-19	2000-04-27	Nye pyridazinderivater, anveldelse derav og medikamenter inneholdende dissesom effektive ingredienser

Country Status (20)

Country	Link
US (11)	US6348468B1 (no)
EP (2)	EP1043317B1 (no)
KR (1)	KR100626605B1 (no)
CN (1)	CN1142148C (no)
AT (1)	ATE428700T1 (no)
AU (1)	AU738595B2 (no)
BR (1)	BR9813998A (no)
CA (1)	CA2307111C (no)
DE (1)	DE69840755D1 (no)
DK (1)	DK1043317T3 (no)
ES (1)	ES2324126T3 (no)
HU (1)	HUP0100059A3 (no)
ID (1)	ID24166A (no)
MX (1)	MXPA00004955A (no)
NO (1)	NO316021B1 (no)
NZ (1)	NZ504045A (no)
PT (1)	PT1043317E (no)
RU (1)	RU2209813C2 (no)
TW (1)	TW502025B (no)
WO (1)	WO1999025697A1 (no)

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DE102005057924A1 (de) *	2005-12-05	2007-06-06	Merck Patent Gmbh	Pyridazinonderivate
US20090203701A1 (en) *	2006-06-29	2009-08-13	Kowa Co., Ltd	Prophylactic and/or therapeutic agent for rheumatoid arthritis
DE102006037478A1 (de) *	2006-08-10	2008-02-14	Merck Patent Gmbh	2-(Heterocyclylbenzyl)-pyridazinonderivate
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TW200838535A (en)	2007-01-29	2008-10-01	Kowa Co	Therapeutic agent for multiple sclerosis
US20100120732A1 (en) *	2007-03-09	2010-05-13	Kowa Co., Ltd.	Agent for prevention and/or treatment of systemic lupus erythematosus
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WO2013097052A1 (en)	2011-12-30	2013-07-04	Abbott Laboratories	Bromodomain inhibitors
CN102603676B (zh) *	2012-02-20	2014-02-12	徐江平	一种能避免呕吐反应的磷酸二酯酶4抑制剂
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1998
- 1998-11-09 CN CNB988113015A patent/CN1142148C/zh not_active Expired - Fee Related
- 1998-11-09 PT PT98951732T patent/PT1043317E/pt unknown
- 1998-11-09 WO PCT/JP1998/005023 patent/WO1999025697A1/ja not_active Ceased
- 1998-11-09 BR BR9813998-3A patent/BR9813998A/pt active Search and Examination
- 1998-11-09 US US09/530,949 patent/US6348468B1/en not_active Expired - Fee Related
- 1998-11-09 AU AU97626/98A patent/AU738595B2/en not_active Ceased
- 1998-11-09 CA CA002307111A patent/CA2307111C/en not_active Expired - Fee Related
- 1998-11-09 ID IDW20000931A patent/ID24166A/id unknown
- 1998-11-09 RU RU2000115577/04A patent/RU2209813C2/ru not_active IP Right Cessation
- 1998-11-09 AT AT98951732T patent/ATE428700T1/de not_active IP Right Cessation
- 1998-11-09 EP EP98951732A patent/EP1043317B1/en not_active Expired - Lifetime
- 1998-11-09 EP EP08019558A patent/EP2017266A1/en not_active Withdrawn
- 1998-11-09 KR KR1020007004967A patent/KR100626605B1/ko not_active Expired - Fee Related
- 1998-11-09 NZ NZ504045A patent/NZ504045A/en unknown
- 1998-11-09 DK DK98951732T patent/DK1043317T3/da active
- 1998-11-09 HU HU0100059A patent/HUP0100059A3/hu unknown
- 1998-11-09 ES ES98951732T patent/ES2324126T3/es not_active Expired - Lifetime
- 1998-11-09 DE DE69840755T patent/DE69840755D1/de not_active Expired - Lifetime
- 1998-11-09 MX MXPA00004955A patent/MXPA00004955A/es not_active IP Right Cessation
- 1998-11-17 TW TW087119032A patent/TW502025B/zh not_active IP Right Cessation
2000
- 2000-04-27 NO NO20002169A patent/NO316021B1/no not_active IP Right Cessation
2001
- 2001-11-30 US US09/996,804 patent/US20020123496A1/en not_active Abandoned
2004
- 2004-01-15 US US10/757,525 patent/US20040147516A1/en not_active Abandoned
- 2004-11-12 US US10/986,350 patent/US20050065155A1/en not_active Abandoned
2005
- 2005-08-15 US US11/203,174 patent/US20050267113A1/en not_active Abandoned
2006
- 2006-03-22 US US11/385,995 patent/US20060160804A1/en not_active Abandoned
- 2006-11-01 US US11/590,811 patent/US20070049595A1/en not_active Abandoned
2007
- 2007-04-30 US US11/741,947 patent/US20070208025A1/en not_active Abandoned
2008
- 2008-01-14 US US12/013,691 patent/US20080119474A1/en not_active Abandoned
- 2008-11-03 US US12/263,816 patent/US20090069332A1/en not_active Abandoned
2009
- 2009-07-06 US US12/497,797 patent/US20090270399A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN1279672A (zh)	2001-01-10
EP1043317B1 (en)	2009-04-15
US20070208025A1 (en)	2007-09-06
KR20010031880A (ko)	2001-04-16
AU9762698A (en)	1999-06-07
US20080119474A1 (en)	2008-05-22
CN1142148C (zh)	2004-03-17
ES2324126T3 (es)	2009-07-30
US20070049595A1 (en)	2007-03-01
CA2307111C (en)	2009-06-30
WO1999025697A1 (en)	1999-05-27
US20090069332A1 (en)	2009-03-12
EP1043317A4 (en)	2003-03-05
PT1043317E (pt)	2009-05-11
US20050267113A1 (en)	2005-12-01
NO20002169L (no)	2000-05-18
BR9813998A (pt)	2000-09-26
TW502025B (en)	2002-09-11
HUP0100059A2 (hu)	2002-02-28
NZ504045A (en)	2001-06-29
MXPA00004955A (es)	2002-10-17
DE69840755D1 (de)	2009-05-28
HK1032969A1 (en)	2001-08-10
AU738595B2 (en)	2001-09-20
US20020123496A1 (en)	2002-09-05
US20090270399A1 (en)	2009-10-29
KR100626605B1 (ko)	2006-09-22
US20050065155A1 (en)	2005-03-24
ID24166A (id)	2000-07-13
RU2209813C2 (ru)	2003-08-10
ATE428700T1 (de)	2009-05-15
NO316021B1 (no)	2003-12-01
US6348468B1 (en)	2002-02-19
DK1043317T3 (da)	2009-07-06
CA2307111A1 (en)	1999-05-27
HUP0100059A3 (en)	2002-08-28
US20040147516A1 (en)	2004-07-29
US20060160804A1 (en)	2006-07-20
EP2017266A1 (en)	2009-01-21
EP1043317A1 (en)	2000-10-11

Legal Events

Date	Code	Title	Description
2011-06-27	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
NO20002169L (no)	2000-05-18	Nye pyridazinderivater og medikamenter inneholdende disse som effektive ingredienser
PT976748E (pt)	2004-03-31	Derivados de pirrolidina com actividade inibidora de fosfolipase a2
DE69434136D1 (de)	2004-12-23	Dolastatin-derivate
EP0900795A4 (en)	2000-12-13	HETEROCYCLICALLY SUBSTITUTED BENZENE DERIVATIVES AND HERBICIDES
NO981269D0 (no)	1998-03-20	Forbindelser som forsterker virkningen av retinoider
DE69839735D1 (de)	2008-08-28	Pyrimidin-5-carboxamid-derivate
ATE268767T1 (de)	2004-06-15	N-aryl-piperidinderivate und ihre verwendung als 5-ht1b-rezeptorliganden
IL124944A (en)	2003-06-24	Quinolonecarboxylic acid derivatives or their salts and pharmaceutical compositions containing them
FR15C0027I1 (no)	2015-05-15
NO913087L (no)	1992-02-10	Ny tricyklisk forbindelse eller salter derav, fremgangsmaate for fremstilling derav og antimikrobielt middel inneholdende slike.
DK0947504T3 (da)	2003-11-24	16-en-vitamin D-derivater
DE60223904D1 (de)	2008-01-17	Benzylaminanalogen
ES2140524T3 (es)	2000-03-01	Derivados de metotrexato.
DE69815347D1 (de)	2003-07-10	Tetrahydrofuranderivate