DK1054064T3 - Vehikler til adenovirus afledt genafgivelse omfattende mindst et element af adenovirus type 35 - Google Patents

Vehikler til adenovirus afledt genafgivelse omfattende mindst et element af adenovirus type 35

Info

Publication number: DK1054064T3
Authority: DK; Denmark
Prior art keywords: adenovirus; serotypes; tropism; proteins; vehicles
Prior art date: 1999-05-17

Application number

DK00201738T

Other languages

English (en)

Other versions

DK1054064T4 (da

Inventor

Abraham Bout

Menzo Jans Emco Havenga

Ronald Vogels

Original Assignee

Crucell Holland Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-17

Filing date

2000-05-16

Publication date

2005-01-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8240209&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1054064(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-05-16 Application filed by Crucell Holland Bv filed Critical Crucell Holland Bv

2005-01-10 Application granted granted Critical

2005-01-10 Publication of DK1054064T3 publication Critical patent/DK1054064T3/da

2010-05-03 Publication of DK1054064T4 publication Critical patent/DK1054064T4/da

Links

241000701161 unidentified adenovirus Species 0.000 title abstract 6
238000001476 gene delivery Methods 0.000 title 1
108090000565 Capsid Proteins Proteins 0.000 abstract 3
102100023321 Ceruloplasmin Human genes 0.000 abstract 3
230000010415 tropism Effects 0.000 abstract 3
108090000623 proteins and genes Proteins 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
101710145505 Fiber protein Proteins 0.000 abstract 1
NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 abstract 1
210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
210000004072 lung Anatomy 0.000 abstract 1
238000012986 modification Methods 0.000 abstract 1
230000004048 modification Effects 0.000 abstract 1
230000010076 replication Effects 0.000 abstract 1
230000000241 respiratory effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/861—Adenoviral vectors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10345—Special targeting system for viral vectors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6009—Vectors comprising as targeting moiety peptide derived from defined protein from viruses dsDNA viruses
- C12N2810/6018—Adenoviridae

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Virology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK00201738.2T 1999-05-17 2000-05-16 Vehikler til adenovirus afledt genafgivelse omfattende mindst et element af adenovirus type 35 DK1054064T4 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP99201545		1999-05-17
PCT/NL2000/000325 WO2000070071A1 (en)	1999-05-17	2000-05-16	Adenovirus derived gene delivery vehicles comprising at least one element of adenovirus type 35

Publications (2)

Publication Number	Publication Date
DK1054064T3 true DK1054064T3 (da)	2005-01-10
DK1054064T4 DK1054064T4 (da)	2010-05-03

Family

ID=8240209

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
DK07106054.5T DK1816205T3 (da)	1999-05-17	2000-05-16	Rekombinant adenovirus på grundlag af serotypen Ad48
DK07106036.2T DK1818408T3 (da)	1999-05-17	2000-05-16	Rekombinant adenovirus af serotypen Ad11
DK04077434T DK1550722T3 (da)	1999-05-17	2000-05-16	Rekombinant human adenovirus serotype 35
DK07106044.6T DK1816204T3 (da)	1999-05-17	2000-05-16	Rekombinant adenovirus af Ad26-serotypen
DK05077719T DK1681353T3 (da)	1999-05-17	2000-05-16	Af adenovirus afledte genoverförselsvehikler indeholdende mindste ét element af adenovirus type 35
DK00201738.2T DK1054064T4 (da)	1999-05-17	2000-05-16	Vehikler til adenovirus afledt genafgivelse omfattende mindst et element af adenovirus type 35

Family Applications Before (5)

Application Number	Title	Priority Date	Filing Date
DK07106054.5T DK1816205T3 (da)	1999-05-17	2000-05-16	Rekombinant adenovirus på grundlag af serotypen Ad48
DK07106036.2T DK1818408T3 (da)	1999-05-17	2000-05-16	Rekombinant adenovirus af serotypen Ad11
DK04077434T DK1550722T3 (da)	1999-05-17	2000-05-16	Rekombinant human adenovirus serotype 35
DK07106044.6T DK1816204T3 (da)	1999-05-17	2000-05-16	Rekombinant adenovirus af Ad26-serotypen
DK05077719T DK1681353T3 (da)	1999-05-17	2000-05-16	Af adenovirus afledte genoverförselsvehikler indeholdende mindste ét element af adenovirus type 35

Country Status (14)

Country	Link
EP (6)	EP1816205B1 (da)
JP (2)	JP4843145B2 (da)
KR (1)	KR100741247B1 (da)
AT (6)	ATE485382T1 (da)
AU (1)	AU777041B2 (da)
CA (1)	CA2372655C (da)
CY (4)	CY1106762T1 (da)
DE (4)	DE60014489T3 (da)
DK (6)	DK1816205T3 (da)
ES (5)	ES2372823T3 (da)
IL (3)	IL146479A0 (da)
NZ (1)	NZ515582A (da)
PT (5)	PT1816205E (da)
WO (1)	WO2000070071A1 (da)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
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US6929946B1 (en)	1998-11-20	2005-08-16	Crucell Holland B.V.	Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
US6869936B1 (en)	1999-03-04	2005-03-22	Crucell Holland B.V.	Means and methods for fibroblast-like or macrophage-like cell transduction
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US6558948B1 (en)	1999-11-23	2003-05-06	Stefan Kochanek	Permanent amniocytic cell line, its production and use for the production of gene transfer vectors
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EP1195440A1 (en) *	2000-10-06	2002-04-10	Introgene B.V.	Gene delivery vectors for stem cells
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BRPI0510475B8 (pt)	2004-05-26	2021-05-25	Bayer Pharma AG	adenovírus quimérico recombinante, uso do mesmo no tratamento de câncer e métodos de inibição de crescimento de uma célula de câncer, de fornecimento de uma proteína terapêutica a uma célula e para o isolamento do adenovírus
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CN102220357B (zh)	2004-11-16	2013-12-25	克鲁塞尔荷兰公司	包含重组病毒载体的多价疫苗
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US8771709B2 (en)	2010-09-20	2014-07-08	Crucell Holland B.V.	Therapeutic vaccination against active Tuberculosis
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Publication number	Publication date
ES2289426T3 (es)	2008-02-01
DE60043126D1 (de)	2009-11-19
AU777041B2 (en)	2004-09-30
WO2000070071A1 (en)	2000-11-23
EP1816205A1 (en)	2007-08-08
PT1054064E (pt)	2005-02-28
ATE519855T1 (de)	2011-08-15
JP4843145B2 (ja)	2011-12-21
KR100741247B1 (ko)	2007-07-19
DE60014489T3 (de)	2010-08-12
CY1112189T1 (el)	2015-12-09
EP1054064A1 (en)	2000-11-22
ES2231103T5 (es)	2010-04-15
ATE364707T1 (de)	2007-07-15
EP1816205B1 (en)	2011-08-10
ES2231103T3 (es)	2005-05-16
CA2372655A1 (en)	2000-11-23
PT1816205E (pt)	2011-11-15
ES2372824T3 (es)	2012-01-26
EP1818408A1 (en)	2007-08-15
IL214413A (en)	2014-04-30
CY1112008T1 (el)	2015-11-04
ATE445018T1 (de)	2009-10-15
DK1681353T3 (da)	2010-01-04
JP2011224014A (ja)	2011-11-10
DK1054064T4 (da)	2010-05-03
EP1550722B1 (en)	2007-06-13
EP1681353B1 (en)	2009-10-07
ATE278792T1 (de)	2004-10-15
CY1106762T1 (el)	2012-05-23
ATE485382T1 (de)	2010-11-15
IL214413A0 (en)	2011-09-27
CA2372655C (en)	2011-11-15
DK1550722T3 (da)	2007-10-08
DE60035229D1 (de)	2007-07-26
EP1550722A1 (en)	2005-07-06
DE60045138D1 (de)	2010-12-02
EP1054064B2 (en)	2009-12-16
AU4954700A (en)	2000-12-05
DK1818408T3 (da)	2011-10-17
IL146479A0 (en)	2002-07-25
JP2002543846A (ja)	2002-12-24
EP1816204A1 (en)	2007-08-08
DK1816204T3 (da)	2011-01-24
ES2372823T3 (es)	2012-01-26
PT1816204E (pt)	2011-01-24
ATE519854T1 (de)	2011-08-15
EP1681353A1 (en)	2006-07-19
PT1818408E (pt)	2011-11-15
NZ515582A (en)	2003-11-28
CY1111494T1 (el)	2015-08-05
DE60014489D1 (de)	2004-11-11
JP5335037B2 (ja)	2013-11-06
PT1550722E (pt)	2007-09-25
IL146479A (en)	2011-12-29
ES2354578T3 (es)	2011-03-16
DK1816205T3 (da)	2011-11-21
DE60035229T2 (de)	2008-02-21
DE60014489T2 (de)	2005-11-24
EP1054064B1 (en)	2004-10-06
EP1818408B1 (en)	2011-08-10
KR20020028879A (ko)	2002-04-17
EP1816204B1 (en)	2010-10-20

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DK1015595T3 (da)	2005-04-11	Peptider afledt fra bindings (G)-proteinet fra respiratorisk syncytialvirus