DK1086071T3 - Hyperforinforbindelser, anvendelse heraf og formuleringer indeholdende disse - Google Patents
Hyperforinforbindelser, anvendelse heraf og formuleringer indeholdende disseInfo
- Publication number
- DK1086071T3 DK1086071T3 DK99926516T DK99926516T DK1086071T3 DK 1086071 T3 DK1086071 T3 DK 1086071T3 DK 99926516 T DK99926516 T DK 99926516T DK 99926516 T DK99926516 T DK 99926516T DK 1086071 T3 DK1086071 T3 DK 1086071T3
- Authority
- DK
- Denmark
- Prior art keywords
- hyperforin
- compounds
- formulations containing
- glicoside
- antidepressive
- Prior art date
Links
- 150000002448 hyperforins Chemical class 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/647—Unsaturated compounds containing a keto groups being part of a ring having unsaturation outside the ring
- C07C49/653—Unsaturated compounds containing a keto groups being part of a ring having unsaturation outside the ring polycyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998MI001312A IT1301679B1 (it) | 1998-06-10 | 1998-06-10 | Derivati dell'iperforina, loro uso e formulazioni che licontengono. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1086071T3 true DK1086071T3 (da) | 2006-01-23 |
Family
ID=11380210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99926516T DK1086071T3 (da) | 1998-06-10 | 1999-06-04 | Hyperforinforbindelser, anvendelse heraf og formuleringer indeholdende disse |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6656510B2 (da) |
| EP (2) | EP1086071B1 (da) |
| JP (1) | JP4511726B2 (da) |
| KR (1) | KR100627933B1 (da) |
| CN (1) | CN1246278C (da) |
| AT (1) | ATE307103T1 (da) |
| AU (1) | AU763889B2 (da) |
| BR (1) | BR9910893B1 (da) |
| CA (1) | CA2334308C (da) |
| CZ (1) | CZ298859B6 (da) |
| DE (1) | DE69927813T2 (da) |
| DK (1) | DK1086071T3 (da) |
| ES (1) | ES2249893T3 (da) |
| HU (1) | HUP0102226A3 (da) |
| IL (2) | IL140151A0 (da) |
| IT (1) | IT1301679B1 (da) |
| MX (1) | MXPA00012177A (da) |
| NO (1) | NO328444B1 (da) |
| PL (1) | PL195797B1 (da) |
| RU (1) | RU2240304C2 (da) |
| SK (1) | SK286049B6 (da) |
| WO (1) | WO1999064388A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000025824A2 (de) * | 1998-11-04 | 2000-05-11 | Dr. Willmar Schwabe Gmbh & Co. | Stabile zubereitungen mit hyperforin |
| ITMI20020871A1 (it) * | 2002-04-23 | 2003-10-23 | Indena Spa | Derivati alogenati dell'iperforina loro uso e formulazioni che li contengono |
| ITMI20020872A1 (it) * | 2002-04-23 | 2003-10-23 | Indena Spa | Derivati dell'iperforina loro uso e formulazioni che li contengono |
| US20060115556A1 (en) * | 2004-12-01 | 2006-06-01 | Foulger Sidney W | Nutritional supplement drink containing xanthone extracts |
| US20060115555A1 (en) * | 2004-12-01 | 2006-06-01 | Foulger Sidney W | Nutritional supplements containing xanthone extracts |
| BRPI0900614A2 (pt) | 2009-02-13 | 2011-06-28 | Univ Fed Do Rio Grande Do Sul Ufrgs | extrato vegetal neuroativo, composição farmacêutica compreendendo o mesmo e processo para sua produção |
| US9321713B2 (en) * | 2011-06-03 | 2016-04-26 | President And Fellows Of Harvard College | Hyperforin analogs, methods of synthesis, and uses thereof |
| ITMI20131012A1 (it) | 2013-06-19 | 2014-12-20 | Indena Spa | Derivati dell'iperforina e loro uso nella malattia di alzheimer |
| RU2676100C1 (ru) * | 2018-10-05 | 2018-12-26 | федеральное государственное автономное образовательное учреждение высшего образования "Санкт-Петербургский политехнический университет Петра Великого" (ФГАОУ ВО "СПбПУ") | Применение производных пиперазина для лечения болезни Альцгеймера и деменций альцгеймеровского типа с нарушенной внутриклеточной кальциевой сигнализацией |
| CN118724815A (zh) * | 2024-06-20 | 2024-10-01 | 中日友好医院(中日友好临床医学研究所) | 一种间苯三酚类化合物Hyperforidiol E及其制备方法和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2550266A (en) * | 1948-12-11 | 1951-04-24 | Swift & Co | Preservation of food products |
| DE4239959A1 (de) * | 1992-11-27 | 1994-06-01 | Schwabe Willmar Gmbh & Co | Johanniskraut-Trockenextrakt, Verfahren zu seiner Herstellung und seine Verwendung |
| DE19646977A1 (de) * | 1995-09-29 | 1998-01-15 | Schwabe Willmar Gmbh & Co | Stabiler Extrakt aus Hypericum perforatum L., Verfahren zu seiner Herstellung und pharmazeutische Zubereitungen |
| DE19714450A1 (de) * | 1997-04-08 | 1998-10-15 | Schwabe Willmar Gmbh & Co | Stabiler Extrakt aus Hypericum perforatum L., Verfahren zu seiner Herstellung und pharmazeutische Zubereitung |
| JP2002509111A (ja) * | 1998-01-13 | 2002-03-26 | レクソール サンダウン インコーポレイテッド | オトギリソウ及びメチル供与体組成物、並びにその使用 |
| US6224906B1 (en) * | 1999-08-31 | 2001-05-01 | Natreon Inc. | St. John's wort composition |
-
1998
- 1998-06-10 IT IT1998MI001312A patent/IT1301679B1/it active IP Right Grant
-
1999
- 1999-06-04 CN CNB998071218A patent/CN1246278C/zh not_active Expired - Fee Related
- 1999-06-04 DE DE69927813T patent/DE69927813T2/de not_active Expired - Lifetime
- 1999-06-04 AT AT99926516T patent/ATE307103T1/de active
- 1999-06-04 EP EP99926516A patent/EP1086071B1/en not_active Expired - Lifetime
- 1999-06-04 KR KR1020007013866A patent/KR100627933B1/ko not_active Expired - Lifetime
- 1999-06-04 PL PL99344696A patent/PL195797B1/pl not_active IP Right Cessation
- 1999-06-04 MX MXPA00012177A patent/MXPA00012177A/es active IP Right Grant
- 1999-06-04 CZ CZ20004562A patent/CZ298859B6/cs not_active IP Right Cessation
- 1999-06-04 SK SK1871-2000A patent/SK286049B6/sk not_active IP Right Cessation
- 1999-06-04 BR BRPI9910893-3B1A patent/BR9910893B1/pt not_active IP Right Cessation
- 1999-06-04 CA CA002334308A patent/CA2334308C/en not_active Expired - Fee Related
- 1999-06-04 RU RU2000131214/04A patent/RU2240304C2/ru not_active IP Right Cessation
- 1999-06-04 EP EP05015870A patent/EP1607099A1/en not_active Withdrawn
- 1999-06-04 JP JP2000553398A patent/JP4511726B2/ja not_active Expired - Fee Related
- 1999-06-04 WO PCT/EP1999/003880 patent/WO1999064388A1/en not_active Ceased
- 1999-06-04 DK DK99926516T patent/DK1086071T3/da active
- 1999-06-04 AU AU43739/99A patent/AU763889B2/en not_active Ceased
- 1999-06-04 HU HU0102226A patent/HUP0102226A3/hu unknown
- 1999-06-04 ES ES99926516T patent/ES2249893T3/es not_active Expired - Lifetime
- 1999-06-04 IL IL14015199A patent/IL140151A0/xx active IP Right Grant
-
2000
- 2000-12-07 IL IL140151A patent/IL140151A/en not_active IP Right Cessation
- 2000-12-07 NO NO20006230A patent/NO328444B1/no not_active IP Right Cessation
- 2000-12-07 US US09/730,536 patent/US6656510B2/en not_active Expired - Lifetime
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