DK1095055T3 - Fremgangsmåde til fremstilling af rekombinante peptider med en lav trisulfidmængde - Google Patents

Fremgangsmåde til fremstilling af rekombinante peptider med en lav trisulfidmængde

Info

Publication number
DK1095055T3
DK1095055T3 DK99933442T DK99933442T DK1095055T3 DK 1095055 T3 DK1095055 T3 DK 1095055T3 DK 99933442 T DK99933442 T DK 99933442T DK 99933442 T DK99933442 T DK 99933442T DK 1095055 T3 DK1095055 T3 DK 1095055T3
Authority
DK
Denmark
Prior art keywords
amount
recombinant peptides
recombinant
preparing recombinant
peptide
Prior art date
Application number
DK99933442T
Other languages
Danish (da)
English (en)
Inventor
Barbro Hemmendorff
Andreas Castan
Anders Persson
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20412012&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1095055(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Application granted granted Critical
Publication of DK1095055T3 publication Critical patent/DK1095055T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99933442T 1998-07-08 1999-07-05 Fremgangsmåde til fremstilling af rekombinante peptider med en lav trisulfidmængde DK1095055T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9802454A SE9802454D0 (sv) 1998-07-08 1998-07-08 Production of peptides
PCT/SE1999/001222 WO2000002900A1 (en) 1998-07-08 1999-07-05 Method for the production of recombinant peptides with a low amount of trisulfides

Publications (1)

Publication Number Publication Date
DK1095055T3 true DK1095055T3 (da) 2003-12-22

Family

ID=20412012

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99933442T DK1095055T3 (da) 1998-07-08 1999-07-05 Fremgangsmåde til fremstilling af rekombinante peptider med en lav trisulfidmængde

Country Status (14)

Country Link
US (2) US7232894B1 (de)
EP (1) EP1095055B1 (de)
JP (1) JP2002520332A (de)
AT (1) ATE248855T1 (de)
AU (1) AU755083B2 (de)
CA (1) CA2344506C (de)
DE (1) DE69911024T2 (de)
DK (1) DK1095055T3 (de)
ES (1) ES2207255T3 (de)
IL (1) IL140668A0 (de)
NZ (1) NZ509179A (de)
PT (1) PT1095055E (de)
SE (1) SE9802454D0 (de)
WO (1) WO2000002900A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2119788A1 (de) 1999-03-02 2009-11-18 Life Technologies Corporation Zusammensetzungen und Verfahren zur Verwendung beim Rekombinationsklonen von Nukleinsäuren
CN101633692A (zh) 1999-06-28 2010-01-27 杰南技术公司 利用二价金属离子制备Apo-2配体的方法
ZA200501841B (en) * 2002-08-28 2007-06-27 Pharmacia Corp Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof
US20040048315A1 (en) 2002-08-28 2004-03-11 Pharmacia Corporation Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof
BRPI0314120B8 (pt) * 2002-09-20 2021-05-25 Pharmacia Corp processo para diminuição de um nível de agregado de um antagonista de hormônio do crescimento (gh) peguilado e isoformas do mesmo
US8304189B2 (en) 2003-12-01 2012-11-06 Life Technologies Corporation Nucleic acid molecules containing recombination sites and methods of using the same
JP4865728B2 (ja) * 2004-12-29 2012-02-01 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト ポリペプチドの三硫化物誘導体の形成を防止する方法
DK2483289T4 (da) 2009-10-02 2025-05-19 Biogen Ma Inc Fremgangsmåder til forebyggelse og fjernelse af trisulfidbindinger
DK2707383T3 (en) 2011-05-13 2018-07-23 Biogen Ma Inc PROCEDURES FOR PREVENTION AND REMOVAL OF TRISULPHIDE BINDINGS
CN106536540A (zh) 2014-07-24 2017-03-22 基因泰克公司 将试剂缀合至含有至少一个三硫键的蛋白质中的巯基部分的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256546A (en) * 1983-07-15 1993-10-26 Bio-Technology General Corp. Bacterial expression of porcine growth hormone
US4985544A (en) * 1987-08-04 1991-01-15 Kyowa Hakko Kogyo Co., Ltd. Process for renaturing fish growth hormone
DK44593D0 (da) * 1993-04-20 1993-04-20 Novo Nordisk As Fremgangsmaade til fremstilling af et polypeptid
US5663304A (en) 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
ZA955789B (en) 1994-07-15 1996-03-11 Novo Nordisk As A method of converting a hydrophobic derivative of a polypeptide into the native form

Also Published As

Publication number Publication date
AU755083B2 (en) 2002-12-05
EP1095055A1 (de) 2001-05-02
EP1095055B1 (de) 2003-09-03
US20070232792A1 (en) 2007-10-04
AU4949699A (en) 2000-02-01
DE69911024T2 (de) 2004-04-01
SE9802454D0 (sv) 1998-07-08
ATE248855T1 (de) 2003-09-15
WO2000002900A1 (en) 2000-01-20
ES2207255T3 (es) 2004-05-16
CA2344506A1 (en) 2000-01-20
NZ509179A (en) 2003-01-31
US7232894B1 (en) 2007-06-19
JP2002520332A (ja) 2002-07-09
DE69911024D1 (de) 2003-10-09
CA2344506C (en) 2010-05-11
PT1095055E (pt) 2003-12-31
IL140668A0 (en) 2002-02-10

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