DK1102596T3 - Peptidantagonister af zonulin og fremgangsmåder til anvendelse heraf - Google Patents

Peptidantagonister af zonulin og fremgangsmåder til anvendelse heraf

Info

Publication number: DK1102596T3
Authority: DK; Denmark
Prior art keywords: peptide antagonists; methods; zonulin; zonulin peptide; opening
Prior art date: 1998-08-03

Application number

DK99940809T

Other languages

Danish (da)

English (en)

Inventor

Alessio Fasano

Original Assignee

Univ Maryland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-03

Filing date

1999-07-28

Publication date

2006-10-09

1999-07-28 Application filed by Univ Maryland filed Critical Univ Maryland

2006-10-09 Application granted granted Critical

2006-10-09 Publication of DK1102596T3 publication Critical patent/DK1102596T3/da

Links

239000005557 antagonist Substances 0.000 title abstract 3
108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
102100025255 Haptoglobin Human genes 0.000 title abstract 2
108010027843 zonulin Proteins 0.000 title abstract 2
210000001578 tight junction Anatomy 0.000 abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4716—Muscle proteins, e.g. myosin, actin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK99940809T 1998-08-03 1999-07-28 Peptidantagonister af zonulin og fremgangsmåder til anvendelse heraf DK1102596T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US09/127,815 US6458925B1 (en)	1998-08-03	1998-08-03	Peptide antagonists of zonulin and methods for use of the same

Publications (1)

Publication Number	Publication Date
DK1102596T3 true DK1102596T3 (da)	2006-10-09

Family

ID=22432094

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99940809T DK1102596T3 (da)	1998-08-03	1999-07-28	Peptidantagonister af zonulin og fremgangsmåder til anvendelse heraf

Country Status (18)

Country	Link
US (10)	US6458925B1 (de)
EP (2)	EP1698345B1 (de)
JP (1)	JP4822585B2 (de)
KR (1)	KR100610389B1 (de)
CN (2)	CN100348266C (de)
AT (2)	ATE480252T1 (de)
AU (1)	AU745507B2 (de)
CA (1)	CA2338005C (de)
DE (2)	DE69942753D1 (de)
DK (1)	DK1102596T3 (de)
ES (1)	ES2267282T3 (de)
HU (1)	HU228079B1 (de)
IL (2)	IL141082A0 (de)
NO (1)	NO326552B1 (de)
NZ (1)	NZ509579A (de)
RU (1)	RU2214267C2 (de)
WO (1)	WO2000007609A1 (de)
ZA (1)	ZA200100829B (de)

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1998
- 1998-08-03 US US09/127,815 patent/US6458925B1/en not_active Expired - Lifetime
1999
- 1999-07-28 ES ES99940809T patent/ES2267282T3/es not_active Expired - Lifetime
- 1999-07-28 CN CNB2005100077127A patent/CN100348266C/zh not_active Expired - Lifetime
- 1999-07-28 AT AT06006483T patent/ATE480252T1/de not_active IP Right Cessation
- 1999-07-28 JP JP2000563294A patent/JP4822585B2/ja not_active Expired - Lifetime
- 1999-07-28 EP EP06006483A patent/EP1698345B1/de not_active Expired - Lifetime
- 1999-07-28 DK DK99940809T patent/DK1102596T3/da active
- 1999-07-28 KR KR1020017001503A patent/KR100610389B1/ko not_active Expired - Lifetime
- 1999-07-28 CA CA2338005A patent/CA2338005C/en not_active Expired - Lifetime
- 1999-07-28 HU HU0103321A patent/HU228079B1/hu unknown
- 1999-07-28 WO PCT/US1999/016683 patent/WO2000007609A1/en not_active Ceased
- 1999-07-28 DE DE69942753T patent/DE69942753D1/de not_active Expired - Lifetime
- 1999-07-28 CN CN998100315A patent/CN1217697C/zh not_active Expired - Lifetime
- 1999-07-28 AT AT99940809T patent/ATE329606T1/de active
- 1999-07-28 RU RU2001106615/14A patent/RU2214267C2/ru active
- 1999-07-28 NZ NZ509579A patent/NZ509579A/en not_active IP Right Cessation
- 1999-07-28 IL IL14108299A patent/IL141082A0/xx unknown
- 1999-07-28 AU AU54590/99A patent/AU745507B2/en not_active Expired
- 1999-07-28 DE DE69931929T patent/DE69931929T2/de not_active Expired - Lifetime
- 1999-07-28 EP EP99940809A patent/EP1102596B1/de not_active Expired - Lifetime
2001
- 2001-01-24 IL IL141082A patent/IL141082A/en not_active IP Right Cessation
- 2001-01-30 ZA ZA2001/00829A patent/ZA200100829B/en unknown
- 2001-02-02 NO NO20010567A patent/NO326552B1/no not_active IP Right Cessation
2002
- 2002-03-13 US US10/095,450 patent/US6670448B2/en not_active Expired - Lifetime
2003
- 2003-08-27 US US10/648,642 patent/US6936689B2/en not_active Expired - Lifetime
2005
- 2005-03-09 US US11/074,727 patent/US7189696B2/en not_active Expired - Fee Related
2006
- 2006-08-08 US US11/500,429 patent/US7531504B2/en not_active Expired - Fee Related
2007
- 2007-08-21 US US11/842,738 patent/US20090082279A1/en not_active Abandoned
- 2007-08-21 US US11/842,763 patent/US7582603B2/en not_active Expired - Fee Related
2010
- 2010-10-20 US US12/908,709 patent/US20110183923A1/en not_active Abandoned
2013
- 2013-01-09 US US13/737,517 patent/US20130190247A1/en not_active Abandoned
- 2013-11-01 US US14/070,208 patent/US20140128328A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2338005C (en)	2012-05-29
US20040082512A1 (en)	2004-04-29
ATE329606T1 (de)	2006-07-15
EP1102596B1 (de)	2006-06-14
EP1102596A4 (de)	2002-08-14
US20080051349A1 (en)	2008-02-28
US7189696B2 (en)	2007-03-13
NO326552B1 (no)	2009-01-05
US6670448B2 (en)	2003-12-30
US20110183923A1 (en)	2011-07-28
US20130190247A1 (en)	2013-07-25
EP1698345B1 (de)	2010-09-08
US20020115825A1 (en)	2002-08-22
US20060276399A1 (en)	2006-12-07
RU2214267C2 (ru)	2003-10-20
IL141082A0 (en)	2002-02-10
US6936689B2 (en)	2005-08-30
ATE480252T1 (de)	2010-09-15
CN1313772A (zh)	2001-09-19
AU5459099A (en)	2000-02-28
EP1102596A1 (de)	2001-05-30
ES2267282T3 (es)	2007-03-01
HK1082210A1 (zh)	2006-06-02
CN1217697C (zh)	2005-09-07
JP4822585B2 (ja)	2011-11-24
CA2338005A1 (en)	2000-02-17
US20050209161A1 (en)	2005-09-22
NO20010567L (no)	2001-04-02
HUP0103321A3 (en)	2006-01-30
DE69931929T2 (de)	2007-02-08
US20090082279A1 (en)	2009-03-26
DE69942753D1 (de)	2010-10-21
EP1698345A3 (de)	2006-09-13
HUP0103321A2 (hu)	2001-12-28
US7582603B2 (en)	2009-09-01
HU228079B1 (en)	2012-10-29
KR100610389B1 (ko)	2006-08-09
JP2002524393A (ja)	2002-08-06
ZA200100829B (en)	2002-06-26
AU745507B2 (en)	2002-03-21
NO20010567D0 (no)	2001-02-02
US6458925B1 (en)	2002-10-01
US20140128328A1 (en)	2014-05-08
DE69931929D1 (de)	2006-07-27
NZ509579A (en)	2003-07-25
US7531504B2 (en)	2009-05-12
EP1698345A2 (de)	2006-09-06
IL141082A (en)	2012-09-24
WO2000007609A1 (en)	2000-02-17
CN100348266C (zh)	2007-11-14
KR20010072245A (ko)	2001-07-31
CN1679915A (zh)	2005-10-12

Publication	Publication Date	Title
NO20010567D0 (no)	2001-02-02	Zonulin peptidantagonister og fremgangsmåter for anvendelse av disse
TR199801255T2 (xx)	1998-10-21	Vitronektin resept�r antagonistleri.
EA200101177A1 (ru)	2002-04-25	Производные индола в качестве антагонистов прогестерона
IL140622A0 (en)	2002-02-10	Biphenyl sufonamide derivatives, pharmaceutical compositions containing the same and methods for the preparation thereof
CY1107821T1 (el)	2013-06-19	Πολυπεπτιδιο παραγοντα viii με ενεργοτητα παραγοντα viii:c
BR0213207A (pt)	2006-10-31	remodelagem e glicoconjugação de peptìdeos
CY1106366T1 (el)	2011-10-12	Ενωση λακταμης για την αναστολη της απελευθερωσης ή της συνθεσης βητα-αμυλοειδους πεπτιδιου
ATE280826T1 (de)	2004-11-15	Cc-chemokinzeptor c-c ckr-5, dessen derivate und verwendungen
TR199700993T1 (xx)	1998-03-21	5-ikameli-3-(1,2,3,6-tetrahidropridin-4-il)- ve 3-(piperidin-4-il)-1H-indoller: yeni 5-HT1F agonistler.
TR200002896T2 (tr)	2001-01-22	Kalsilitik Bileşimler
TR200001012T2 (tr)	2000-09-21	Yeni ariloksi-alkil-dialkilaminler.
DE69824719D1 (de)	2004-07-29	Cytokinähnlicher faktor-7 aus säugetieren
ATE274348T1 (de)	2004-09-15	Überbrückte indenopyrrolocarbazole
TR200100462T2 (tr)	2001-09-21	Muskarinik agonistleri ve antagonistleri
EA200201138A1 (ru)	2003-06-26	Пептид, модулирующий рецептор тромбопоэтина
EA200000086A1 (ru)	2000-08-28	Алатрофлоксациновые парентеральные составы
PE20010516A1 (es)	2001-04-29	Peptidos ciclicos con afinidad mejorada por los receptores de somatostatina
ATE359294T1 (de)	2007-05-15	Toxinrezeptoren aus zonula occludens
TR200102041T2 (tr)	2001-12-21	Progesteron reseptör bağlama aktif maddeleri olarak ikameli 2-arilimino heterosaykıllar
DK0783521T3 (da)	2003-01-27	Polypeptidforbindelser indeholdende D-2-alkyltryptophan, hvilke er i stand til at fremme frigivelsen af væksthormon
DE69920717D1 (de)	2004-11-04	Glucocorticoid selektive entzündungshemmende mittel
ATE385805T1 (de)	2008-03-15	Neue peptide
TR200002072T2 (tr)	2000-12-21	Spiropiperidin türevleri
DE69725459D1 (de)	2003-11-13	Substituierte 1,2,3,4-tetrahydro-2-dibenzofuranamine und 2-aminocyclohepta(b)benzofurane
EA200000875A1 (ru)	2001-10-22	Белки, взаимодействующие с каспазой-8