DK1112106T3 - Serotonerge 5HT2-agonister til behandling af glaukom - Google Patents

Serotonerge 5HT2-agonister til behandling af glaukom

Info

Publication number
DK1112106T3
DK1112106T3 DK99948085T DK99948085T DK1112106T3 DK 1112106 T3 DK1112106 T3 DK 1112106T3 DK 99948085 T DK99948085 T DK 99948085T DK 99948085 T DK99948085 T DK 99948085T DK 1112106 T3 DK1112106 T3 DK 1112106T3
Authority
DK
Denmark
Prior art keywords
serotonergic
glaucoma
agonists
treatment
Prior art date
Application number
DK99948085T
Other languages
English (en)
Inventor
Jesse A May
Thomas R Dean
Mark R Hellberg
Najam A Sharif
Original Assignee
Alcon Mfg Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Mfg Ltd filed Critical Alcon Mfg Ltd
Application granted granted Critical
Publication of DK1112106T3 publication Critical patent/DK1112106T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK99948085T 1998-09-18 1999-09-03 Serotonerge 5HT2-agonister til behandling af glaukom DK1112106T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10106798P 1998-09-18 1998-09-18

Publications (1)

Publication Number Publication Date
DK1112106T3 true DK1112106T3 (da) 2005-12-12

Family

ID=22282920

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99948085T DK1112106T3 (da) 1998-09-18 1999-09-03 Serotonerge 5HT2-agonister til behandling af glaukom

Country Status (17)

Country Link
US (2) US6664286B1 (da)
EP (1) EP1112106B1 (da)
JP (1) JP2002526443A (da)
KR (1) KR20010073153A (da)
CN (1) CN1269484C (da)
AR (1) AR020442A1 (da)
AT (1) ATE310566T1 (da)
AU (1) AU755119B2 (da)
BR (1) BR9913800A (da)
CA (1) CA2344150A1 (da)
DE (1) DE69928542T2 (da)
DK (1) DK1112106T3 (da)
ES (1) ES2252978T3 (da)
TR (1) TR200100754T2 (da)
TW (1) TWI229602B (da)
WO (1) WO2000016761A2 (da)
ZA (1) ZA200102157B (da)

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ATE317846T1 (de) * 2000-03-31 2006-03-15 Purdue Research Foundation Phosphoramidat-prodrugs
CA2447156A1 (en) 2001-06-01 2002-12-12 Alcon, Inc. Novel fused indazoles and indoles and their use for the treatment of glaucoma
ATE318821T1 (de) 2001-06-01 2006-03-15 Alcon Inc Pyranoindazole und ihre verwendung in der glaukombehandlung
WO2002098400A1 (en) 2001-06-01 2002-12-12 Alcon, Inc. Novel arylaminopropane analogues and their use for the treatment of glaucoma
US6884816B2 (en) * 2001-08-31 2005-04-26 Alcon, Inc. Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
TW593302B (en) * 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
MXPA05002259A (es) * 2002-08-30 2005-07-05 Alcon Inc Compuestos de 5-croman-5-il-etilamina sustituidos y uso para el tratamiento de glaucoma.
WO2004028451A2 (en) * 2002-09-24 2004-04-08 Virginia Commonwealth University β-HYDROXYPHENYLALKYLAMINES AND THEIR USE FOR TREATING GLAUCOMA
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WO2005053688A1 (en) * 2003-11-26 2005-06-16 Alcon, Inc. Substituted furo[2,3-g] indazoles for the treatment of glaucoma
AR046890A1 (es) * 2003-12-15 2005-12-28 Alcon Inc [1,4] oxazino [2,3-g] indazoles sustituidos para el tratamiento del glaucoma.
US7129257B1 (en) 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
EP1744784A2 (en) * 2004-05-11 2007-01-24 Becton, Dickinson and Company Formulations of anti-pain agents and methods of using the same
EP1792629A4 (en) 2004-08-25 2010-08-25 Takeda Pharmaceutical MEANS FOR THE PREVENTION / TREATMENT OF STRESS-RELATED HARNINE INCONTINENCE AND PRECAUTIONARY METHOD FOR THIS
US7425572B2 (en) * 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
US20060211700A1 (en) * 2005-03-21 2006-09-21 Alcon, Inc. (R)-8,9-dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one for controlling IOP and treating glaucoma
TW200744567A (en) * 2005-09-23 2007-12-16 Alcon Inc Phenylethylamine analogs and their use for treating glaucoma
EP2727585A1 (en) 2006-05-16 2014-05-07 Takeda Pharmaceutical Company Limited In-vivo screening method
US20070293475A1 (en) * 2006-06-20 2007-12-20 Alcon Manufacturing Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
CL2008003120A1 (es) 2007-11-01 2009-10-09 Acucela Inc Compuestos derivados de fenilalquil-, fenilalquenil-, fenilalquinil- amina, feniltioalquilamina, fenilaminoalquilamina, fenilalcoxiamina y fenilalquilguanidina; composicion farmaceutica; y uso de los compuestos para tratar un trastorno o enfermedad oftalmologica tal como retinopatia, maculopatia, retinitis pigmentosa, uveitis, entre otras.
EP2216023A4 (en) 2007-11-15 2013-03-13 Takeda Pharmaceutical CONDENSED PYRIDINE DERIVATIVE AND ITS USE
US9642819B2 (en) * 2008-07-10 2017-05-09 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical Low dosage serotonin 5-HT2A receptor agonist to suppress inflammation
US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
JPWO2011071136A1 (ja) 2009-12-11 2013-04-22 アステラス製薬株式会社 線維筋痛症治療剤
TW201210584A (en) 2010-08-18 2012-03-16 Alcon Res Ltd Bradykinin receptor agonists and uses thereof to treat ocular hypertension and glaucoma
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
JPWO2019131902A1 (ja) 2017-12-27 2020-12-10 武田薬品工業株式会社 腹圧性尿失禁および便失禁の治療薬
JP2022529781A (ja) 2019-04-17 2022-06-24 コンパス パスファインダー リミテッド サイロシビンによるうつ病及び他の様々な障害の治療
WO2024010765A1 (en) * 2022-07-05 2024-01-11 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions for treating 5-ht2 conditions and methods of using the same

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Also Published As

Publication number Publication date
WO2000016761A3 (en) 2000-05-25
CN1317979A (zh) 2001-10-17
AU6132699A (en) 2000-04-10
DE69928542T2 (de) 2006-03-30
TWI229602B (en) 2005-03-21
ZA200102157B (en) 2003-03-05
ATE310566T1 (de) 2005-12-15
WO2000016761A2 (en) 2000-03-30
BR9913800A (pt) 2001-05-29
HK1038516A1 (en) 2002-03-22
KR20010073153A (ko) 2001-07-31
DE69928542D1 (de) 2005-12-29
AR020442A1 (es) 2002-05-15
TR200100754T2 (tr) 2001-10-22
CN1269484C (zh) 2006-08-16
AU755119B2 (en) 2002-12-05
EP1112106A2 (en) 2001-07-04
JP2002526443A (ja) 2002-08-20
CA2344150A1 (en) 2000-03-30
US20030203912A1 (en) 2003-10-30
EP1112106B1 (en) 2005-11-23
US6664286B1 (en) 2003-12-16
ES2252978T3 (es) 2006-05-16

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