DK1114861T3 - LY6H-gen - Google Patents

LY6H-gen

Info

Publication number
DK1114861T3
DK1114861T3 DK99943357T DK99943357T DK1114861T3 DK 1114861 T3 DK1114861 T3 DK 1114861T3 DK 99943357 T DK99943357 T DK 99943357T DK 99943357 T DK99943357 T DK 99943357T DK 1114861 T3 DK1114861 T3 DK 1114861T3
Authority
DK
Denmark
Prior art keywords
gene
expression vector
product
disease
ly6h gene
Prior art date
Application number
DK99943357T
Other languages
Danish (da)
English (en)
Inventor
Masato Horie
Keiichi Okutomi
Yutaka Ohbuchi
Yoshihiro Taniguchi
Mikio Suzuki
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK1114861T3 publication Critical patent/DK1114861T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
DK99943357T 1998-09-17 1999-09-16 LY6H-gen DK1114861T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26355098 1998-09-17
PCT/JP1999/005039 WO2000017345A1 (en) 1998-09-17 1999-09-16 Ly6h gene

Publications (1)

Publication Number Publication Date
DK1114861T3 true DK1114861T3 (da) 2007-03-19

Family

ID=17391112

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99943357T DK1114861T3 (da) 1998-09-17 1999-09-16 LY6H-gen

Country Status (16)

Country Link
US (4) US7432363B2 (de)
EP (1) EP1114861B8 (de)
JP (1) JP4403443B2 (de)
KR (1) KR100640265B1 (de)
CN (1) CN1240834C (de)
AT (1) ATE346923T1 (de)
AU (1) AU767878B2 (de)
BR (1) BR9913850A (de)
CA (1) CA2342770C (de)
CY (1) CY1107552T1 (de)
DE (1) DE69934239T8 (de)
DK (1) DK1114861T3 (de)
ES (1) ES2276531T3 (de)
ID (1) ID29573A (de)
PT (1) PT1114861E (de)
WO (1) WO2000017345A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU767878B2 (en) * 1998-09-17 2003-11-27 Otsuka Pharmaceutical Co., Ltd. LY6H gene
WO2003020702A2 (en) 2001-08-31 2003-03-13 The Rockefeller University Phosphodiesterase activity and regulation of phosphodiesterase 1-b-mediated signaling in brain
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
PT1976877E (pt) 2005-11-30 2014-04-29 Abbvie Inc Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações
BRPI0619249A2 (pt) 2005-11-30 2011-09-20 Abbott Lab anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
US7875431B2 (en) * 2007-02-22 2011-01-25 Genentech, Inc. Methods for detecting inflammatory bowel disease
EP2124952A2 (de) 2007-02-27 2009-12-02 Abbott GmbH & Co. KG Verfahren zur behandlung von amyloidosen
JP6166534B2 (ja) 2009-08-05 2017-07-19 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 新規調節タンパク質および阻害剤
EP2558494B1 (de) 2010-04-15 2018-05-23 AbbVie Inc. Amyloid-beta-bindende proteine
CN105348387B (zh) 2010-08-14 2020-08-25 Abbvie 公司 β淀粉样蛋白结合蛋白
US20140286910A1 (en) * 2013-03-19 2014-09-25 Nikolai Tankovich Stem cells and methods incorporating environmental factors as a means for enhancing stem cell proliferation and plasticity
CN105385754B (zh) * 2015-10-28 2018-11-06 北京泱深生物信息技术有限公司 一种与胆管癌相关的分子标记物
US11434303B2 (en) * 2017-06-28 2022-09-06 Bluefin Biomedicine, Inc. Anti-LY6H antibodies and antibody drug conjugates
EP3658172A4 (de) 2017-07-25 2021-05-05 TrueBinding, Inc. Behandlung von krebs durch blockierung der interaktion von tim-3 und seinem liganden
KR102232200B1 (ko) * 2019-03-13 2021-03-25 아주대학교산학협력단 알츠하이머치매 진단 바이오마커
CN113711036B (zh) 2019-01-30 2025-03-18 真和制药有限公司 抗gal3抗体及其用途
CN116157151A (zh) 2020-05-26 2023-05-23 真和制药有限公司 通过阻断半乳凝素-3治疗炎性疾病的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011912A (en) 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
JPH0348696A (ja) * 1989-07-14 1991-03-01 Toray Ind Inc ヒトリンパ球表面抗原およびそれをコードする遺伝子
WO1997018224A1 (en) * 1995-11-13 1997-05-22 Human Genome Sciences, Inc. Human stem cell antigen 2
JP2002500009A (ja) * 1997-12-31 2002-01-08 インサイト・ファーマスーティカルズ・インコーポレイテッド ヒトシグナルペプチド含有タンパク質
AU767878B2 (en) * 1998-09-17 2003-11-27 Otsuka Pharmaceutical Co., Ltd. LY6H gene

Also Published As

Publication number Publication date
US20040254340A1 (en) 2004-12-16
AU5651899A (en) 2000-04-10
DE69934239T2 (de) 2007-06-28
CN1318099A (zh) 2001-10-17
PT1114861E (pt) 2007-01-31
JP4403443B2 (ja) 2010-01-27
EP1114861B1 (de) 2006-11-29
US7582732B2 (en) 2009-09-01
US20100261880A1 (en) 2010-10-14
US7432363B2 (en) 2008-10-07
KR20010085801A (ko) 2001-09-07
EP1114861A4 (de) 2004-10-13
HK1038380A1 (en) 2002-03-15
ID29573A (id) 2001-09-06
AU767878B2 (en) 2003-11-27
CA2342770A1 (en) 2000-03-30
CY1107552T1 (el) 2013-03-13
KR100640265B1 (ko) 2006-10-31
ATE346923T1 (de) 2006-12-15
EP1114861B8 (de) 2008-10-01
CA2342770C (en) 2011-06-21
US20080275218A1 (en) 2008-11-06
DE69934239D1 (de) 2007-01-11
WO2000017345A1 (en) 2000-03-30
CN1240834C (zh) 2006-02-08
US20090017479A1 (en) 2009-01-15
EP1114861A1 (de) 2001-07-11
DE69934239T8 (de) 2007-12-06
ES2276531T3 (es) 2007-06-16
BR9913850A (pt) 2001-10-23

Similar Documents

Publication Publication Date Title
CY1107552T1 (el) Ly6h γονιδιο
WO1999053061A3 (en) Tumor associated nucleic acids and uses therefor
DE69636866D1 (en) Reverse "two-hybrid"-systeme
EP0804609A4 (de) NEUARTIGE AUF p53 ANSPRECHENDE GENE
DE69635207D1 (de) Auf Chromosom 1 lokalisiertes Gen dessen Genprodukt mit der Alzheimerschen Krankheit assoziiert ist.
CY1106806T1 (el) Dna και πολυπεπτιδια ανθρωπινης tslp
DK1005540T3 (da) IKK-beta-proteiner, nukleinsyrer og fremgangsmåder
ATE394484T1 (de) Smad 6 und dessen anwendungen
IL135687A0 (en) A novel human checkpoint kinase, hcds1, compositions and methods
WO2003011898A3 (fr) Peptides synthetiques ou naturels liant la proteine phosphatase 2a, methode d'identification et utilisations
WO2002004677A3 (en) Methods for diagnosis and treatment of psychiatric disorders
AU2001238064A1 (en) 18477, a human protein kinase and uses therefor
WO1997002730A3 (en) Enamel matrix related polypeptide
WO2001059120A3 (en) Il-17 like molecules and uses thereof
EP0816498A3 (de) Exzitatorische Aminosäure Rezeptor-Protein und verwante Nukleinsäure
AU2002350406A1 (en) Identification of ses-3 (spr-5) in c. elegans and the uses of the same
WO2004003170A3 (en) Agents capable of inhibiting ras and uses thereof
AU2002314193A1 (en) Identification of ses-1 and the uses of the same
WO2000008143A3 (de) Gen isoliert auf dem kurzen arm des menschlichen chromosoms 17
WO2003051174A3 (en) Single nucleotide polymorphisms and mutations on alpha-2-macroglobulin
EP1430070A4 (de) Neues clark-protein und nukleinsäuremoleküle und deren verwendungen
WO2002000827A3 (fr) Nouveau polypeptide, proteine de methylation d'adn-cysteine methyl-transferase 10, et polynucleotide codant ce polypeptide