NO332460B1 - Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling. - Google Patents

Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling. Download PDF

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Publication number
NO332460B1
NO332460B1 NO20012223A NO20012223A NO332460B1 NO 332460 B1 NO332460 B1 NO 332460B1 NO 20012223 A NO20012223 A NO 20012223A NO 20012223 A NO20012223 A NO 20012223A NO 332460 B1 NO332460 B1 NO 332460B1
Authority
NO
Norway
Prior art keywords
nogo
protein
nucleic acid
sequence
seq
Prior art date
Application number
NO20012223A
Other languages
English (en)
Norwegian (no)
Other versions
NO20012223L (no
NO20012223D0 (no
Inventor
Martin E Schwab
Maio S Chen
Original Assignee
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO332460(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Zuerich filed Critical Univ Zuerich
Publication of NO20012223D0 publication Critical patent/NO20012223D0/no
Publication of NO20012223L publication Critical patent/NO20012223L/no
Publication of NO332460B1 publication Critical patent/NO332460B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
NO20012223A 1998-11-06 2001-05-04 Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling. NO332460B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06
PCT/US1999/026160 WO2000031235A2 (en) 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon

Publications (3)

Publication Number Publication Date
NO20012223D0 NO20012223D0 (no) 2001-05-04
NO20012223L NO20012223L (no) 2001-07-02
NO332460B1 true NO332460B1 (no) 2012-09-24

Family

ID=22316666

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012223A NO332460B1 (no) 1998-11-06 2001-05-04 Renset humant NOGO protein, fusjon- eller kimaert protein, isolert nukleinsyre, kloningsvektor, rekombinant celle, fremgangsmate for fremstilling av proteinet, samt anvendelse av proteinet for fremstilling av et medikament for behandling.

Country Status (26)

Country Link
US (4) US7781188B1 (da)
EP (3) EP1124846B1 (da)
JP (2) JP2003531566A (da)
KR (1) KR100728405B1 (da)
CN (3) CN101684155A (da)
AT (1) ATE435232T1 (da)
AU (1) AU774367C (da)
BR (1) BR9915137A (da)
CA (1) CA2350395C (da)
CY (1) CY1110679T1 (da)
CZ (1) CZ304224B6 (da)
DE (1) DE69941059D1 (da)
DK (1) DK1124846T3 (da)
ES (2) ES2329635T3 (da)
HU (1) HUP0301829A3 (da)
IL (3) IL142989A0 (da)
MX (1) MXPA01004598A (da)
NO (1) NO332460B1 (da)
NZ (1) NZ511683A (da)
PL (1) PL204293B1 (da)
PT (1) PT1124846E (da)
RU (3) RU2304585C2 (da)
SK (1) SK287323B6 (da)
TR (1) TR200700740T2 (da)
WO (1) WO2000031235A2 (da)
ZA (1) ZA200103714B (da)

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US20020072493A1 (en) 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
JP2002522016A (ja) * 1998-07-22 2002-07-23 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 神経内分泌特異的タンパク質に類似したタンパク質、およびそれをコードするｃＤＮＡ
CN101684155A (zh) 1998-11-06 2010-03-31 苏黎世大学 Nogo基因的核苷酸序列和蛋白序列以及基于其的方法
WO2000060083A1 (en) * 1999-04-08 2000-10-12 Chiron Corporation Novel protein associated with cell stress response
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
HK1051543A1 (zh) * 2000-01-12 2003-08-08 Yale University Nogo受体介导的轴突生长封锁
US7119165B2 (en) 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
DE60141409D1 (de) 2000-10-06 2010-04-08 Biogen Idec Inc Homologe des nogo rezeptors
GB0101312D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
AR040778A1 (es) 2002-08-06 2005-04-20 Glaxo Group Ltd Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina).
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
US20060287501A1 (en) * 2002-10-31 2006-12-21 Pieris Proteolab Ag Soluble truncated polypeptides of the nogo-a protein
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
EP2213684A3 (en) * 2003-12-22 2011-05-18 Glaxo Group Limited Nogo-a antibodies for the treatment of Alzheimer disease
US8486893B2 (en) 2004-06-24 2013-07-16 Biogen Idec Ma Inc. Treatment of conditions involving demyelination
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
SG157418A1 (en) * 2004-12-01 2009-12-29 Univ Singapore Nogo a protein fragments as neuronal network- interacting peptides
WO2007008732A2 (en) 2005-07-07 2007-01-18 Yale University Compositions and methods for suppressing axonal growth inhibition
HRP20131066T1 (hr) 2005-07-08 2013-12-06 Biogen Idec Ma Inc. Sp35 antitijela i njihova upotreba
WO2007014382A1 (en) * 2005-07-28 2007-02-01 Wyeth Compositions and methods of mutant nogo-66 domain proteins
BRPI0618609A2 (pt) 2005-11-16 2011-09-06 Novartis Ag biomarcadores para tratamento com anticorpo anti-nogo-a em danos à medula espinhal
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
US20080025959A1 (en) * 2006-05-24 2008-01-31 Richard Daneman Permeability of blood-brain barrier
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
MX2010004831A (es) * 2007-11-02 2010-05-21 Novartis Ag Moleculas de enlace de nogo-a mejoradas y uso farmaceutico de las mismas.
RU2476886C2 (ru) * 2007-11-22 2013-02-27 Симфоген А/С Способ характеризации рекомбинантного поликлонального белка
CA2729961C (en) 2008-07-09 2018-05-01 Biogen Idec Ma Inc. Li113, li62 variant co2, anti-lingo antibodies
CA2764153C (en) * 2009-06-02 2021-07-27 The Board Of Regents Of The University Of Texas System Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
KR102142161B1 (ko) 2012-05-14 2020-08-06 바이오젠 엠에이 인코포레이티드 운동 뉴런 관련 병태 치료용 lingo-2 길항제
MX366880B (es) * 2013-08-08 2019-07-29 Global Bio Therapeutics Inc Dispositivo de inyección para procedimientos mínimamente invasivos y usos del mismo.
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
JP2018504400A (ja) 2015-01-08 2018-02-15 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． Ｌｉｎｇｏ‐１拮抗薬及び脱髄障害の治療のための使用
US20180015144A1 (en) * 2015-01-27 2018-01-18 Universitat Zurich Agonists of the nogo-a s1pr pathway for the treatment of glioblastoma

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US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
CA1173823A (en) 1980-08-26 1984-09-04 Leonard M. Hjelmeland Nondenaturing zwitterionic detergent for membrane biochemistry
CA1341401C (en) 1984-03-23 2002-11-26 Adriano Fontana Immunosuppressant factor derived from human glioblastoma cells
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US5250414A (en) 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
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US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
JP2002522016A (ja) * 1998-07-22 2002-07-23 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 神経内分泌特異的タンパク質に類似したタンパク質、およびそれをコードするｃＤＮＡ
WO2000011015A1 (en) * 1998-08-24 2000-03-02 Alphagene, Inc. Secreted proteins and polynucleotides encoding them
CN101684155A (zh) 1998-11-06 2010-03-31 苏黎世大学 Nogo基因的核苷酸序列和蛋白序列以及基于其的方法
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Also Published As

Publication number Publication date
RU2432364C2 (ru) 2011-10-27
US20050260616A1 (en) 2005-11-24
RU2304585C2 (ru) 2007-08-20
AU774367B2 (en) 2004-06-24
RU2001115705A (ru) 2004-03-10
CA2350395C (en) 2014-07-08
ES2329635T3 (es) 2009-11-27
DE69941059D1 (de) 2009-08-13
EP2333064A1 (en) 2011-06-15
PT1124846E (pt) 2009-10-08
ES2529196T3 (es) 2015-02-17
NZ511683A (en) 2004-06-25
PL204293B1 (pl) 2009-12-31
IL142989A0 (en) 2002-04-21
CY1110679T1 (el) 2015-06-10
PL362990A1 (en) 2004-11-15
KR100728405B1 (ko) 2007-06-13
EP1124846A2 (en) 2001-08-22
JP2003531566A (ja) 2003-10-28
RU2358982C2 (ru) 2009-06-20
EP1124846B1 (en) 2009-07-01
TR200700740T2 (tr) 2007-04-24
EP2093294B1 (en) 2014-10-29
HUP0301829A3 (en) 2009-03-30
JP2012213406A (ja) 2012-11-08
MXPA01004598A (es) 2002-04-24
RU2009103533A (ru) 2010-11-10
CN1721444A (zh) 2006-01-18
KR20020003353A (ko) 2002-01-12
BR9915137A (pt) 2004-06-08
CN101684155A (zh) 2010-03-31
CA2350395A1 (en) 2000-06-02
NO20012223L (no) 2001-07-02
DK1124846T3 (da) 2009-10-26
HUP0301829A2 (hu) 2003-08-28
IL198027A (en) 2011-10-31
US7781188B1 (en) 2010-08-24
CZ20011608A3 (cs) 2001-10-17
NO20012223D0 (no) 2001-05-04
WO2000031235A3 (en) 2000-11-09
US20090162367A1 (en) 2009-06-25
US7425334B2 (en) 2008-09-16
ZA200103714B (en) 2004-06-25
CN1354755B (zh) 2010-06-02
AU1469200A (en) 2000-06-13
CZ304224B6 (cs) 2014-01-15
SK287323B6 (sk) 2010-07-07
EP2093294A1 (en) 2009-08-26
IL142989A (en) 2010-12-30
HK1038027A1 (en) 2002-03-01
ATE435232T1 (de) 2009-07-15
RU2004103555A (ru) 2005-07-20
SK6222001A3 (en) 2001-12-03
WO2000031235A2 (en) 2000-06-02
AU774367C (en) 2005-04-21
US20110086034A1 (en) 2011-04-14
CN1354755A (zh) 2002-06-19
EP1124846A4 (en) 2002-06-12

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