DK1135383T3 - Blandede paroxetin-propan-2-ol-solvater - Google Patents
Blandede paroxetin-propan-2-ol-solvaterInfo
- Publication number
- DK1135383T3 DK1135383T3 DK99973027T DK99973027T DK1135383T3 DK 1135383 T3 DK1135383 T3 DK 1135383T3 DK 99973027 T DK99973027 T DK 99973027T DK 99973027 T DK99973027 T DK 99973027T DK 1135383 T3 DK1135383 T3 DK 1135383T3
- Authority
- DK
- Denmark
- Prior art keywords
- propan
- mixed
- solvate
- paroxetine
- solvates
- Prior art date
Links
- 239000012453 solvate Substances 0.000 title abstract 5
- AHOUBRCZNHFOSL-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine Chemical compound C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 abstract 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 229960005183 paroxetine hydrochloride Drugs 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 230000009466 transformation Effects 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000008280 chlorinated hydrocarbons Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9826182.9A GB9826182D0 (en) | 1998-11-30 | 1998-11-30 | Novel process |
| GBGB9916257.0A GB9916257D0 (en) | 1999-07-12 | 1999-07-12 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1135383T3 true DK1135383T3 (da) | 2004-04-05 |
Family
ID=26314751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99973027T DK1135383T3 (da) | 1998-11-30 | 1999-11-30 | Blandede paroxetin-propan-2-ol-solvater |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1408039A3 (da) |
| JP (1) | JP2002531452A (da) |
| AT (1) | ATE255577T1 (da) |
| AU (1) | AU1397900A (da) |
| DE (1) | DE69913377T2 (da) |
| DK (1) | DK1135383T3 (da) |
| ES (1) | ES2211232T3 (da) |
| PT (1) | PT1135383E (da) |
| WO (1) | WO2000032594A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL1017421C2 (nl) | 2001-02-21 | 2002-01-15 | Synthon Bv | Werkwijze voor het vervaardigen van paroxetine. |
| WO2007054978A2 (en) * | 2005-11-10 | 2007-05-18 | Jubilant Organosys Limited | Process for preparing paroxetine hydrochloride hemihydrate |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| GB8430581D0 (en) * | 1984-12-04 | 1985-01-09 | Ferrosan As | Treatment |
| EP0223403B1 (en) * | 1985-10-25 | 1993-08-04 | Beecham Group Plc | Piperidine derivative, its preparation, and its use as medicament |
| SK283608B6 (sk) * | 1995-02-06 | 2003-10-07 | Smithkline Beecham Plc | Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie |
| EP0812827B1 (en) * | 1996-06-13 | 2009-09-02 | Sumitomo Chemical Company, Limited | Piperidine derivative as intermediates for the preparation of paroxetine and process for their preparation |
| HU221921B1 (hu) * | 1996-07-08 | 2003-02-28 | Richter Gedeon Vegyészeti Gyár Rt. | N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására |
-
1999
- 1999-11-30 DK DK99973027T patent/DK1135383T3/da active
- 1999-11-30 WO PCT/GB1999/003993 patent/WO2000032594A1/en not_active Ceased
- 1999-11-30 EP EP03078795A patent/EP1408039A3/en not_active Withdrawn
- 1999-11-30 EP EP99973027A patent/EP1135383B1/en not_active Expired - Lifetime
- 1999-11-30 AU AU13979/00A patent/AU1397900A/en not_active Abandoned
- 1999-11-30 ES ES99973027T patent/ES2211232T3/es not_active Expired - Lifetime
- 1999-11-30 JP JP2000585236A patent/JP2002531452A/ja not_active Withdrawn
- 1999-11-30 AT AT99973027T patent/ATE255577T1/de active
- 1999-11-30 DE DE69913377T patent/DE69913377T2/de not_active Expired - Lifetime
- 1999-11-30 PT PT99973027T patent/PT1135383E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1135383E (pt) | 2004-04-30 |
| ES2211232T3 (es) | 2004-07-01 |
| ATE255577T1 (de) | 2003-12-15 |
| EP1408039A2 (en) | 2004-04-14 |
| WO2000032594A1 (en) | 2000-06-08 |
| EP1135383A1 (en) | 2001-09-26 |
| DE69913377T2 (de) | 2004-12-30 |
| AU1397900A (en) | 2000-06-19 |
| DE69913377D1 (de) | 2004-01-15 |
| EP1408039A3 (en) | 2004-05-12 |
| JP2002531452A (ja) | 2002-09-24 |
| EP1135383B1 (en) | 2003-12-03 |
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