ATE255577T1 - Gemischte paroxetin-propan-2-olsolvate - Google Patents

Gemischte paroxetin-propan-2-olsolvate

Info

Publication number: ATE255577T1
Authority: AT; Austria
Prior art keywords: solvate; mixed; paroxetine; propane; propan
Prior art date: 1998-11-30

Application number

AT99973027T

Other languages

English (en)

Inventor

Andrew Simon Craig

Victor Witold Jacewicz

Neal Ward

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-30

Filing date

1999-11-30

Publication date

2003-12-15

1998-11-30 Priority claimed from GBGB9826182.9A external-priority patent/GB9826182D0/en

1999-07-12 Priority claimed from GBGB9916257.0A external-priority patent/GB9916257D0/en

1999-11-30 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2003-12-15 Application granted granted Critical

2003-12-15 Publication of ATE255577T1 publication Critical patent/ATE255577T1/de

Links

239000012453 solvate Substances 0.000 title abstract 5
AHOUBRCZNHFOSL-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine Chemical compound C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 abstract 4
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
229960005183 paroxetine hydrochloride Drugs 0.000 abstract 2
239000002904 solvent Substances 0.000 abstract 2
230000009466 transformation Effects 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
150000008280 chlorinated hydrocarbons Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
150000002576 ketones Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000002825 nitriles Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)

AT99973027T 1998-11-30 1999-11-30 Gemischte paroxetin-propan-2-olsolvate ATE255577T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9826182.9A GB9826182D0 (en)	1998-11-30	1998-11-30	Novel process
GBGB9916257.0A GB9916257D0 (en)	1999-07-12	1999-07-12	Novel compounds
PCT/GB1999/003993 WO2000032594A1 (en)	1998-11-30	1999-11-30	Mixed paroxetine propan-2-ol solvates

Publications (1)

Publication Number	Publication Date
ATE255577T1 true ATE255577T1 (de)	2003-12-15

Family

ID=26314751

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99973027T ATE255577T1 (de)	1998-11-30	1999-11-30	Gemischte paroxetin-propan-2-olsolvate

Country Status (9)

Country	Link
EP (2)	EP1408039A3 (de)
JP (1)	JP2002531452A (de)
AT (1)	ATE255577T1 (de)
AU (1)	AU1397900A (de)
DE (1)	DE69913377T2 (de)
DK (1)	DK1135383T3 (de)
ES (1)	ES2211232T3 (de)
PT (1)	PT1135383E (de)
WO (1)	WO2000032594A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL1017421C2 (nl)	2001-02-21	2002-01-15	Synthon Bv	Werkwijze voor het vervaardigen van paroxetine.
WO2007054978A2 (en) *	2005-11-10	2007-05-18	Jubilant Organosys Limited	Process for preparing paroxetine hydrochloride hemihydrate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1422263A (en) *	1973-01-30	1976-01-21	Ferrosan As	4-phenyl-piperidine compounds
GB8430581D0 (en) *	1984-12-04	1985-01-09	Ferrosan As	Treatment
EP0223403B1 (de) *	1985-10-25	1993-08-04	Beecham Group Plc	Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel
AR001982A1 (es) *	1995-02-06	1998-01-07	Smithkline Beecham Plc	Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion
EP1394160A1 (de) *	1996-06-13	2004-03-03	SUMIKA FINE CHEMICALS Co., Ltd.	Verfahren zur Herstellung von kristallinem Paroxetin-Hydrochlorid
HU221921B1 (hu) *	1996-07-08	2003-02-28	Richter Gedeon Vegyészeti Gyár Rt.	N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására

1999
- 1999-11-30 EP EP03078795A patent/EP1408039A3/de not_active Withdrawn
- 1999-11-30 AT AT99973027T patent/ATE255577T1/de active
- 1999-11-30 AU AU13979/00A patent/AU1397900A/en not_active Abandoned
- 1999-11-30 WO PCT/GB1999/003993 patent/WO2000032594A1/en not_active Ceased
- 1999-11-30 EP EP99973027A patent/EP1135383B1/de not_active Expired - Lifetime
- 1999-11-30 PT PT99973027T patent/PT1135383E/pt unknown
- 1999-11-30 DK DK99973027T patent/DK1135383T3/da active
- 1999-11-30 JP JP2000585236A patent/JP2002531452A/ja not_active Withdrawn
- 1999-11-30 ES ES99973027T patent/ES2211232T3/es not_active Expired - Lifetime
- 1999-11-30 DE DE69913377T patent/DE69913377T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
PT1135383E (pt)	2004-04-30
EP1408039A3 (de)	2004-05-12
ES2211232T3 (es)	2004-07-01
WO2000032594A1 (en)	2000-06-08
EP1135383B1 (de)	2003-12-03
DE69913377D1 (de)	2004-01-15
EP1135383A1 (de)	2001-09-26
AU1397900A (en)	2000-06-19
EP1408039A2 (de)	2004-04-14
JP2002531452A (ja)	2002-09-24
DK1135383T3 (da)	2004-04-05
DE69913377T2 (de)	2004-12-30

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2004-06-15

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