ATE255103T1 - Verfahren zur herstellung von pyridinmethanol- verbindungen - Google Patents

Verfahren zur herstellung von pyridinmethanol- verbindungen

Info

Publication number: ATE255103T1
Authority: AT; Austria
Prior art keywords: pyridine methanol; producing pyridine; methanol compounds; compounds; producing
Prior art date: 1999-12-13

Application number

AT00962909T

Other languages

English (en)

Inventor

E Iishi

Kanami Yoshikawa

Original Assignee

Sumika Fine Chemicals Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-13

Filing date

2000-09-28

Publication date

2003-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18431365&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE255103(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-09-28 Application filed by Sumika Fine Chemicals Co Ltd filed Critical Sumika Fine Chemicals Co Ltd

2003-12-15 Application granted granted Critical

2003-12-15 Publication of ATE255103T1 publication Critical patent/ATE255103T1/de

Links

238000004519 manufacturing process Methods 0.000 title 1
VRWLBMGRSLQKSU-UHFFFAOYSA-N methanol;pyridine Chemical class OC.C1=CC=NC=C1 VRWLBMGRSLQKSU-UHFFFAOYSA-N 0.000 title 1
-1 pyridinemethanol compound Chemical class 0.000 abstract 2
230000001430 anti-depressive effect Effects 0.000 abstract 1
239000000935 antidepressant agent Substances 0.000 abstract 1
229940005513 antidepressants Drugs 0.000 abstract 1
229910052987 metal hydride Inorganic materials 0.000 abstract 1
150000004681 metal hydrides Chemical class 0.000 abstract 1
229960001785 mirtazapine Drugs 0.000 abstract 1
RONZAEMNMFQXRA-UHFFFAOYSA-N mirtazapine Chemical compound C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 RONZAEMNMFQXRA-UHFFFAOYSA-N 0.000 abstract 1
HJIGRHPMRXZAEJ-UHFFFAOYSA-M potassium;pyridine-2-carboxylate Chemical compound [K+].[O-]C(=O)C1=CC=CC=N1 HJIGRHPMRXZAEJ-UHFFFAOYSA-M 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT00962909T 1999-12-13 2000-09-28 Verfahren zur herstellung von pyridinmethanol- verbindungen ATE255103T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP35351499		1999-12-13
PCT/JP2000/005384 WO2001042239A1 (en)	1999-12-13	2000-08-11	Process for the preparation of a pyridinemethanol compound
PCT/JP2000/006688 WO2001042240A1 (fr)	1999-12-13	2000-09-28	Procede de preparation d'un compose pyridinemethanol

Publications (1)

Publication Number	Publication Date
ATE255103T1 true ATE255103T1 (de)	2003-12-15

Family

ID=18431365

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00962909T ATE255103T1 (de)	1999-12-13	2000-09-28	Verfahren zur herstellung von pyridinmethanol- verbindungen

Country Status (12)

Country	Link
US (2)	US6376668B1 (de)
EP (1)	EP1238977B2 (de)
JP (1)	JP3930736B2 (de)
AT (1)	ATE255103T1 (de)
AU (2)	AU6474200A (de)
CA (1)	CA2394439C (de)
DE (1)	DE60006857T3 (de)
DK (1)	DK1238977T4 (de)
ES (1)	ES2209985T5 (de)
IL (2)	IL150120A0 (de)
PT (1)	PT1238977E (de)
WO (2)	WO2001042239A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL358548A1 (en) *	2000-04-24	2004-08-09	Teva Pharmaceutical Industries Ltd.	Zolpidem hemitartrate
JP2005501808A (ja) *	2001-03-01	2005-01-20	テバファーマシューティカルインダストリーズリミティド	ミルタザピン中間体の製造方法
CZ296992B6 (cs) *	2002-10-03	2006-08-16	Zentiva, A.S.	Príprava a izolace 2-substituovaných-3-pyridylkarboxylových kyselin, jejich karboxylových solí a produktu redukce
UA83666C2 (ru) *	2003-07-10	2008-08-11	Н.В. Органон	Способ получения энантиомерно чистого миртазапина
US7838029B1 (en)	2003-07-31	2010-11-23	Watson Laboratories, Inc.	Mirtazapine solid dosage forms
TW200538100A (en) *	2004-04-21	2005-12-01	Akzo Nobel Nv	Mirtazapine salts
EP2146993B1 (de)	2007-04-11	2015-08-05	Merck Sharp & Dohme B.V.	Methode zur herstellung von mirtazapin
US20080255348A1 (en) *	2007-04-11	2008-10-16	N.V. Organon	Method for the preparation of an enantiomer of a tetracyclic benzazepine
WO2010046851A1 (en) *	2008-10-22	2010-04-29	Watson Pharma Private Limited	Process for the preparation of 1- ( 3-hydroxymethylpyrid-2 -yl ) -2 -phenyl-4-methylpiperazine and mirtazapine
JP6433809B2 (ja) *	2015-02-20	2018-12-05	株式会社トクヤマ	１−（３−ヒドロキシメチルピリジル−２−）−２−フェニル−４−メチルピペラジンの製造方法
PT3261645T (pt)	2015-02-27	2021-06-17	Dechra Ltd	Estimulação do apetite, gestão da perda de peso, e tratamento da anorexia em cães e gatos
JP6571497B2 (ja) *	2015-11-13	2019-09-04	株式会社トクヤマ	ミルタザピンの製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL189199C (nl)	1975-04-05	1993-02-01	Akzo Nv	Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
US5196532A (en) *	1989-02-08	1993-03-23	Basf Aktiengesellschaft	Diaryl-substituted heterocyclic compounds, their preparation and drugs and cosmetics obtained therefrom
CZ20013658A3 (cs) *	1999-04-19	2002-08-14	Teva Pharmaceutical Industries Ltd.	Syntéza a krystalizace sloučenin obsahujících piperazinový kruh
HK1042696A1 (zh) *	1999-04-19	2002-08-23	Teva Pharmaceutical Industries Ltd.	哌嗪环的新合成方法
JP3817424B2 (ja) †	2000-12-28	2006-09-06	キヤノン株式会社	シート折り装置及びこれを備えた画像形成装置

2000
- 2000-08-11 WO PCT/JP2000/005384 patent/WO2001042239A1/ja not_active Ceased
- 2000-08-11 AU AU64742/00A patent/AU6474200A/en not_active Abandoned
- 2000-09-28 PT PT00962909T patent/PT1238977E/pt unknown
- 2000-09-28 ES ES00962909T patent/ES2209985T5/es not_active Expired - Lifetime
- 2000-09-28 DE DE60006857T patent/DE60006857T3/de not_active Expired - Lifetime
- 2000-09-28 CA CA002394439A patent/CA2394439C/en not_active Expired - Fee Related
- 2000-09-28 JP JP2001543539A patent/JP3930736B2/ja not_active Expired - Fee Related
- 2000-09-28 WO PCT/JP2000/006688 patent/WO2001042240A1/ja not_active Ceased
- 2000-09-28 IL IL15012000A patent/IL150120A0/xx active IP Right Grant
- 2000-09-28 EP EP00962909A patent/EP1238977B2/de not_active Expired - Lifetime
- 2000-09-28 AU AU74472/00A patent/AU771484B2/en not_active Ceased
- 2000-09-28 AT AT00962909T patent/ATE255103T1/de active
- 2000-09-28 DK DK00962909.8T patent/DK1238977T4/da active
- 2000-11-07 US US09/706,803 patent/US6376668B1/en not_active Expired - Fee Related
2001
- 2001-10-19 US US09/981,919 patent/US6437120B1/en not_active Expired - Fee Related
2002
- 2002-06-10 IL IL150120A patent/IL150120A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO2001042239A1 (en)	2001-06-14
JP3930736B2 (ja)	2007-06-13
CA2394439C (en)	2007-09-11
US6437120B1 (en)	2002-08-20
ES2209985T5 (es)	2010-12-03
DE60006857D1 (de)	2004-01-08
IL150120A0 (en)	2002-12-01
IL150120A (en)	2007-09-20
WO2001042240A1 (fr)	2001-06-14
DE60006857T3 (de)	2011-02-10
DK1238977T4 (da)	2010-10-11
DE60006857T2 (de)	2004-08-26
US6376668B1 (en)	2002-04-23
PT1238977E (pt)	2004-03-31
US20020035255A1 (en)	2002-03-21
AU771484B2 (en)	2004-03-25
EP1238977A4 (de)	2003-02-12
ES2209985T3 (es)	2004-07-01
DK1238977T3 (da)	2004-03-08
CA2394439A1 (en)	2001-06-14
EP1238977B2 (de)	2010-07-21
AU6474200A (en)	2001-06-18
AU7447200A (en)	2001-06-18
EP1238977A1 (de)	2002-09-11
EP1238977B1 (de)	2003-11-26

Legal Events

Date

Code

Title

Description

2004-08-15

UEP

Publication of translation of european patent specification

Ref document number: 1238977

Country of ref document: EP

2011-08-15

EEIH

Change in the person of patent owner

2012-01-15

UEP