DK1173471T3 - Pseudomycinanaloger - Google Patents

Pseudomycinanaloger

Info

Publication number: DK1173471T3
Authority: DK; Denmark
Prior art keywords: pseudomycin; pseudomycins; analogues; nmr; mass spectrometry
Prior art date: 1999-04-15

Application number

DK00921593T

Other languages

English (en)

Inventor

Palaniappan Kulanthaivel

Matthew David Belvo

James William Martin

Thomas John Perun Jr

Douglas Joseph Zeckner

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-15

Filing date

2000-04-14

Publication date

2008-08-18

2000-04-14 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2008-08-18 Application granted granted Critical

2008-08-18 Publication of DK1173471T3 publication Critical patent/DK1173471T3/da

Links

238000005481 NMR spectroscopy Methods 0.000 abstract 2
238000004949 mass spectrometry Methods 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
NYRWZRIVFVWNTD-SGRJACMKSA-N (2s)-2-[(3s,6s,9z,12s,15s,18s,21s,24r,27s)-18-(4-aminobutyl)-15,24-bis(2-aminoethyl)-21-(carboxymethyl)-3-[(1s)-2-chloro-1-hydroxyethyl]-9-ethylidene-12-[(1s)-1-hydroxyethyl]-27-[[(3r)-3-hydroxytetradecanoyl]amino]-2,5,8,11,14,17,20,23,26-nonaoxo-1-oxa-4, Chemical compound CCCCCCCCCCC[C@@H](O)CC(=O)N[C@H]1COC(=O)[C@H]([C@H](O)CCl)NC(=O)[C@H]([C@H](O)C(O)=O)NC(=O)\C(=C\C)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CCN)NC1=O NYRWZRIVFVWNTD-SGRJACMKSA-N 0.000 abstract 1
XDPWWEOIDYYUDN-HCEIJDMSSA-N 2-[(9z)-18-(4-aminobutyl)-15,24-bis(2-aminoethyl)-21-(carboxymethyl)-3-(2-chloro-1-hydroxyethyl)-27-(3,4-dihydroxytetradecanoylamino)-9-ethylidene-12-(1-hydroxyethyl)-2,5,8,11,14,17,20,23,26-nonaoxo-1-oxa-4,7,10,13,16,19,22,25-octazacyclooctacos-6-yl]-2-h Chemical compound CCCCCCCCCCC(O)C(O)CC(=O)NC1COC(=O)C(C(O)CCl)NC(=O)C(C(O)C(O)=O)NC(=O)\C(=C\C)NC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCCCN)NC(=O)C(CC(O)=O)NC(=O)C(CCN)NC1=O XDPWWEOIDYYUDN-HCEIJDMSSA-N 0.000 abstract 1
230000000843 anti-fungal effect Effects 0.000 abstract 1
229930014626 natural product Natural products 0.000 abstract 1
108010033876 pseudomycin A Proteins 0.000 abstract 1
108010033821 pseudomycin B Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK00921593T 1999-04-15 2000-04-14 Pseudomycinanaloger DK1173471T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12944799P	1999-04-15	1999-04-15
PCT/US2000/008727 WO2000063237A2 (en)	1999-04-15	2000-04-14	Pseudomycin analogs

Publications (1)

Publication Number	Publication Date
DK1173471T3 true DK1173471T3 (da)	2008-08-18

Family

ID=22439989

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00921593T DK1173471T3 (da)	1999-04-15	2000-04-14	Pseudomycinanaloger

Country Status (17)

Country	Link
US (2)	US6630147B1 (da)
EP (1)	EP1173471B1 (da)
JP (1)	JP2002542257A (da)
CN (1)	CN1191269C (da)
AT (1)	ATE393773T1 (da)
AU (1)	AU4188700A (da)
BR (1)	BR0009731A (da)
CA (1)	CA2369136A1 (da)
DE (1)	DE60038735T2 (da)
DK (1)	DK1173471T3 (da)
EA (1)	EA004308B1 (da)
ES (1)	ES2304954T3 (da)
HU (1)	HUP0200896A3 (da)
MX (1)	MXPA01010245A (da)
NO (1)	NO20014937L (da)
PT (1)	PT1173471E (da)
WO (1)	WO2000063237A2 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6919188B1 (en)	1999-04-15	2005-07-19	Eli Lilly And Company	Pseudomycin production by Pseudomonas syringae
MXPA03001493A (es) *	2000-08-18	2003-06-06	Univ Montana Res Dev Inst	Seudomicinas utiles contra enfermedades de plantas.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5576298A (en) *	1992-11-30	1996-11-19	Research And Development Institute, Inc. At Montana State University	Peptides from pseudomonas syringae possessing broad-spectrum antibiotic activity
EP1171576B1 (en) *	1999-04-15	2007-07-11	Eli Lilly And Company	Pseudomycin production by pseudomonas syringae
HUP0200897A2 (en) *	1999-04-15	2002-08-28	Lilly Co Eli	Antifungal agents isolated from pseudomonas syringae
CA2396513A1 (en) *	1999-12-13	2001-06-14	Yanzhi Zhang	Pseudomycin phosphate prodrugs

2000
- 2000-04-14 DE DE60038735T patent/DE60038735T2/de not_active Expired - Fee Related
- 2000-04-14 EP EP00921593A patent/EP1173471B1/en not_active Expired - Lifetime
- 2000-04-14 AT AT00921593T patent/ATE393773T1/de not_active IP Right Cessation
- 2000-04-14 BR BR0009731-4A patent/BR0009731A/pt not_active Application Discontinuation
- 2000-04-14 ES ES00921593T patent/ES2304954T3/es not_active Expired - Lifetime
- 2000-04-14 US US09/958,995 patent/US6630147B1/en not_active Expired - Fee Related
- 2000-04-14 HU HU0200896A patent/HUP0200896A3/hu unknown
- 2000-04-14 AU AU41887/00A patent/AU4188700A/en not_active Abandoned
- 2000-04-14 CN CNB008062587A patent/CN1191269C/zh not_active Expired - Fee Related
- 2000-04-14 WO PCT/US2000/008727 patent/WO2000063237A2/en not_active Ceased
- 2000-04-14 JP JP2000612327A patent/JP2002542257A/ja active Pending
- 2000-04-14 CA CA002369136A patent/CA2369136A1/en not_active Abandoned
- 2000-04-14 EA EA200101090A patent/EA004308B1/ru not_active IP Right Cessation
- 2000-04-14 PT PT00921593T patent/PT1173471E/pt unknown
- 2000-04-14 MX MXPA01010245A patent/MXPA01010245A/es active IP Right Grant
- 2000-04-14 DK DK00921593T patent/DK1173471T3/da active
2001
- 2001-10-10 NO NO20014937A patent/NO20014937L/no not_active Application Discontinuation
2003
- 2003-08-07 US US10/636,376 patent/US6793925B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
PT1173471E (pt)	2008-07-21
EP1173471B1 (en)	2008-04-30
US6630147B1 (en)	2003-10-07
CA2369136A1 (en)	2000-10-26
WO2000063237A3 (en)	2001-01-04
NO20014937D0 (no)	2001-10-10
BR0009731A (pt)	2002-03-05
EA200101090A1 (ru)	2002-06-27
AU4188700A (en)	2000-11-02
HUP0200896A3 (en)	2002-09-30
JP2002542257A (ja)	2002-12-10
DE60038735D1 (de)	2008-06-12
MXPA01010245A (es)	2002-03-27
CN1191269C (zh)	2005-03-02
EA004308B1 (ru)	2004-02-26
CN1355812A (zh)	2002-06-26
EP1173471A2 (en)	2002-01-23
WO2000063237A2 (en)	2000-10-26
US20040067879A1 (en)	2004-04-08
DE60038735T2 (de)	2009-07-02
ES2304954T3 (es)	2008-11-01
ATE393773T1 (de)	2008-05-15
US6793925B2 (en)	2004-09-21
NO20014937L (no)	2001-12-13
HUP0200896A2 (en)	2002-08-28

Publication	Publication Date	Title
HN2000000109A (es)	2001-02-02	Trifluorbutenos nematicidas
MY126559A (en)	2006-10-31	Fungicidal 2-methoxybenzophenones
TR200002921T2 (tr)	2001-02-21	Yarı-Sentetik ekteinasidinler
ATE288900T1 (de)	2005-02-15	Substituierte benzoylcyclohexandione
MXPA04001686A (es)	2004-05-31	Combinaciones de productos activos fungicidas.
ATE202483T1 (de)	2001-07-15	Immuntolerante prothrombinkomplex-präparation
MXPA03009602A (es)	2004-04-02	Analogos de nociceptina.
BR0012751A (pt)	2002-06-04	Benzofuranos serotonérgicos
TR199900403T2 (xx)	2002-01-21	Amorf benzotiofenler, haz�rlama y�ntemleri ve kullanma y�ntemleri.
DK1173471T3 (da)	2008-08-18	Pseudomycinanaloger
DE60043228D1 (de)	2009-12-10	Herstellungsverfahren von 2-cyanopyridinen
IL138638A0 (en)	2001-10-31	Processes for preparing intermediates
ATE213236T1 (de)	2002-02-15	Substituierte benzyloxyimino-verbindungen
BR9908415A (pt)	2000-10-17	Fungicidas.
SE9800865D0 (sv)	1998-03-16	New Process
ATE247649T1 (de)	2003-09-15	Disubstituierte biphenyloxazoline
ATE265418T1 (de)	2004-05-15	Neue substituierte 3-phenoxy- und 3- phenylalkyloxy-2-phenyl-propylamine
ATE275551T1 (de)	2004-09-15	Halogenpyrimidine
BG104964A (bg)	2001-07-31	Подобрен метод за получаване на фармацевтично ценни норбензоморфанови производни
ZA200103910B (en)	2002-07-31	1,4-Diaryl-2-fluoro-1-buten-3-ol compounds and their use in the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene and 1,4-diaryl-2-fluoro-2-butene compounds.
ATE292627T1 (de)	2005-04-15	Hydroxamsäurederivate
IT1317000B1 (it)	2003-05-26	Uso di composti di origine naturale ad attivita' antiangiogenica.
WO2000020441A3 (en)	2000-11-23	Cyclic peptides as antifungal agents
PT1140932E (pt)	2004-08-31	Derivados de 1,8-benzonaftiridina
UA31206A (uk)	2000-12-15	Речовина 1,1-(2"-бром-2"-хлоретенил)-біс-(5-фторурацил)-у , яка має протипухлинну активність