DK1173471T3 - Pseudomycinanaloger - Google Patents

Pseudomycinanaloger

Info

Publication number: DK1173471T3
Authority: DK; Denmark
Prior art keywords: pseudomycin; pseudomycins; analogues; nmr; mass spectrometry
Prior art date: 1999-04-15

Application number

DK00921593T

Other languages

English (en)

Inventor

Palaniappan Kulanthaivel

Matthew David Belvo

James William Martin

Thomas John Perun Jr

Douglas Joseph Zeckner

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-15

Filing date

2000-04-14

Publication date

2008-08-18

2000-04-14 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2008-08-18 Application granted granted Critical

2008-08-18 Publication of DK1173471T3 publication Critical patent/DK1173471T3/da

Links

238000005481 NMR spectroscopy Methods 0.000 abstract 2
238000004949 mass spectrometry Methods 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
NYRWZRIVFVWNTD-SGRJACMKSA-N (2s)-2-[(3s,6s,9z,12s,15s,18s,21s,24r,27s)-18-(4-aminobutyl)-15,24-bis(2-aminoethyl)-21-(carboxymethyl)-3-[(1s)-2-chloro-1-hydroxyethyl]-9-ethylidene-12-[(1s)-1-hydroxyethyl]-27-[[(3r)-3-hydroxytetradecanoyl]amino]-2,5,8,11,14,17,20,23,26-nonaoxo-1-oxa-4, Chemical compound CCCCCCCCCCC[C@@H](O)CC(=O)N[C@H]1COC(=O)[C@H]([C@H](O)CCl)NC(=O)[C@H]([C@H](O)C(O)=O)NC(=O)\C(=C\C)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CCN)NC1=O NYRWZRIVFVWNTD-SGRJACMKSA-N 0.000 abstract 1
XDPWWEOIDYYUDN-HCEIJDMSSA-N 2-[(9z)-18-(4-aminobutyl)-15,24-bis(2-aminoethyl)-21-(carboxymethyl)-3-(2-chloro-1-hydroxyethyl)-27-(3,4-dihydroxytetradecanoylamino)-9-ethylidene-12-(1-hydroxyethyl)-2,5,8,11,14,17,20,23,26-nonaoxo-1-oxa-4,7,10,13,16,19,22,25-octazacyclooctacos-6-yl]-2-h Chemical compound CCCCCCCCCCC(O)C(O)CC(=O)NC1COC(=O)C(C(O)CCl)NC(=O)C(C(O)C(O)=O)NC(=O)\C(=C\C)NC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCCCN)NC(=O)C(CC(O)=O)NC(=O)C(CCN)NC1=O XDPWWEOIDYYUDN-HCEIJDMSSA-N 0.000 abstract 1
230000000843 anti-fungal effect Effects 0.000 abstract 1
229930014626 natural product Natural products 0.000 abstract 1
108010033876 pseudomycin A Proteins 0.000 abstract 1
108010033821 pseudomycin B Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK00921593T 1999-04-15 2000-04-14 Pseudomycinanaloger DK1173471T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US12944799P	1999-04-15	1999-04-15
PCT/US2000/008727 WO2000063237A2 (en)	1999-04-15	2000-04-14	Pseudomycin analogs

Publications (1)

Publication Number	Publication Date
DK1173471T3 true DK1173471T3 (da)	2008-08-18

Family

ID=22439989

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00921593T DK1173471T3 (da)	1999-04-15	2000-04-14	Pseudomycinanaloger

Country Status (17)

Country	Link
US (2)	US6630147B1 (da)
EP (1)	EP1173471B1 (da)
JP (1)	JP2002542257A (da)
CN (1)	CN1191269C (da)
AT (1)	ATE393773T1 (da)
AU (1)	AU4188700A (da)
BR (1)	BR0009731A (da)
CA (1)	CA2369136A1 (da)
DE (1)	DE60038735T2 (da)
DK (1)	DK1173471T3 (da)
EA (1)	EA004308B1 (da)
ES (1)	ES2304954T3 (da)
HU (1)	HUP0200896A3 (da)
MX (1)	MXPA01010245A (da)
NO (1)	NO20014937L (da)
PT (1)	PT1173471E (da)
WO (1)	WO2000063237A2 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6919188B1 (en) *	1999-04-15	2005-07-19	Eli Lilly And Company	Pseudomycin production by Pseudomonas syringae
JP2004517044A (ja) *	2000-08-18	2004-06-10	リサーチ・アンド・ディヴェロップメント・インスティテュート・インコーポレイテッド	植物病に対して有用なシュードマイシン類

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5576298A (en)	1992-11-30	1996-11-19	Research And Development Institute, Inc. At Montana State University	Peptides from pseudomonas syringae possessing broad-spectrum antibiotic activity
MXPA01010246A (es) *	1999-04-15	2002-03-27	Lilly Co Eli	Produccion de pseudomicina por pseudomonas syringae.
EA200101086A1 (ru) *	1999-04-15	2002-04-25	Эли Лилли Энд Компани	Антигрибковые агенты, выделенные из pseudomonas syringae
WO2001041534A2 (en) *	1999-12-13	2001-06-14	Eli Lilly And Company	Pseudomycin phosphate prodrugs

2000
- 2000-04-14 CN CNB008062587A patent/CN1191269C/zh not_active Expired - Fee Related
- 2000-04-14 PT PT00921593T patent/PT1173471E/pt unknown
- 2000-04-14 BR BR0009731-4A patent/BR0009731A/pt not_active Application Discontinuation
- 2000-04-14 EA EA200101090A patent/EA004308B1/ru not_active IP Right Cessation
- 2000-04-14 MX MXPA01010245A patent/MXPA01010245A/es active IP Right Grant
- 2000-04-14 EP EP00921593A patent/EP1173471B1/en not_active Expired - Lifetime
- 2000-04-14 JP JP2000612327A patent/JP2002542257A/ja active Pending
- 2000-04-14 DK DK00921593T patent/DK1173471T3/da active
- 2000-04-14 ES ES00921593T patent/ES2304954T3/es not_active Expired - Lifetime
- 2000-04-14 DE DE60038735T patent/DE60038735T2/de not_active Expired - Fee Related
- 2000-04-14 CA CA002369136A patent/CA2369136A1/en not_active Abandoned
- 2000-04-14 WO PCT/US2000/008727 patent/WO2000063237A2/en not_active Ceased
- 2000-04-14 HU HU0200896A patent/HUP0200896A3/hu unknown
- 2000-04-14 AT AT00921593T patent/ATE393773T1/de not_active IP Right Cessation
- 2000-04-14 AU AU41887/00A patent/AU4188700A/en not_active Abandoned
- 2000-04-14 US US09/958,995 patent/US6630147B1/en not_active Expired - Fee Related
2001
- 2001-10-10 NO NO20014937A patent/NO20014937L/no not_active Application Discontinuation
2003
- 2003-08-07 US US10/636,376 patent/US6793925B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
NO20014937D0 (no)	2001-10-10
MXPA01010245A (es)	2002-03-27
WO2000063237A3 (en)	2001-01-04
US6630147B1 (en)	2003-10-07
US20040067879A1 (en)	2004-04-08
HUP0200896A2 (en)	2002-08-28
EP1173471B1 (en)	2008-04-30
DE60038735D1 (de)	2008-06-12
NO20014937L (no)	2001-12-13
DE60038735T2 (de)	2009-07-02
US6793925B2 (en)	2004-09-21
EA004308B1 (ru)	2004-02-26
AU4188700A (en)	2000-11-02
CN1355812A (zh)	2002-06-26
EP1173471A2 (en)	2002-01-23
HUP0200896A3 (en)	2002-09-30
BR0009731A (pt)	2002-03-05
ATE393773T1 (de)	2008-05-15
JP2002542257A (ja)	2002-12-10
CN1191269C (zh)	2005-03-02
PT1173471E (pt)	2008-07-21
WO2000063237A2 (en)	2000-10-26
CA2369136A1 (en)	2000-10-26
EA200101090A1 (ru)	2002-06-27
ES2304954T3 (es)	2008-11-01

Publication	Publication Date	Title
HN2000000109A (es)	2001-02-02	Trifluorbutenos nematicidas
MY126559A (en)	2006-10-31	Fungicidal 2-methoxybenzophenones
TR200002921T2 (tr)	2001-02-21	Yarı-Sentetik ekteinasidinler
ATE288900T1 (de)	2005-02-15	Substituierte benzoylcyclohexandione
MXPA04001686A (es)	2004-05-31	Combinaciones de productos activos fungicidas.
ATE202483T1 (de)	2001-07-15	Immuntolerante prothrombinkomplex-präparation
MXPA03009602A (es)	2004-04-02	Analogos de nociceptina.
DK1204659T3 (da)	2004-04-05	Serotonerge benzofuraner
BG105766A (en)	2002-03-29	New process for preparing pesticidal intermediates
TR199900403T2 (xx)	2002-01-21	Amorf benzotiofenler, haz�rlama y�ntemleri ve kullanma y�ntemleri.
NO20014937D0 (no)	2001-10-10	Naturlige pseudomycinprodukter
DE60043228D1 (de)	2009-12-10	Herstellungsverfahren von 2-cyanopyridinen
GB9806409D0 (en)	1998-05-20	Processes for preparing intermediates
ATE213236T1 (de)	2002-02-15	Substituierte benzyloxyimino-verbindungen
BR9908415A (pt)	2000-10-17	Fungicidas.
SE9800865D0 (sv)	1998-03-16	New Process
BR9808210A (pt)	2000-05-16	Befeniloxazolinas dissubstituìdas
DK1131273T3 (da)	2004-03-01	1,4-Diaryl-2-fluor-1-buten-3-olforbindelser og deres anvendelse til fremstilling af 1,4-diaryl-2-fluor-1,3-butadien- og 1,4-diaryl-2-fluor-2-butenforbindelser
ATE292627T1 (de)	2005-04-15	Hydroxamsäurederivate
IT1317000B1 (it)	2003-05-26	Uso di composti di origine naturale ad attivita' antiangiogenica.
UA31206A (uk)	2000-12-15	Речовина 1,1-(2"-бром-2"-хлоретенил)-біс-(5-фторурацил)-у , яка має протипухлинну активність
ATE244217T1 (de)	2003-07-15	Herstellung von beta-mehtylcarbapenem- zwischenprodukten
ES2151820A1 (es)	2001-01-01	Herbicidas a base de derivados de 1,3-oxazin-4-ona, composiciones que los contienen y procedimiento para su preparacion.