DK1187601T3 - Hidtil ukendt præparat og administrationsform som omfatter en syrelabil protonpumpeinhibitor - Google Patents

Hidtil ukendt præparat og administrationsform som omfatter en syrelabil protonpumpeinhibitor

Info

Publication number
DK1187601T3
DK1187601T3 DK00935151T DK00935151T DK1187601T3 DK 1187601 T3 DK1187601 T3 DK 1187601T3 DK 00935151 T DK00935151 T DK 00935151T DK 00935151 T DK00935151 T DK 00935151T DK 1187601 T3 DK1187601 T3 DK 1187601T3
Authority
DK
Denmark
Prior art keywords
acid
administration
proton pump
pump inhibitor
novel composition
Prior art date
Application number
DK00935151T
Other languages
English (en)
Inventor
Rango Dietrich
Rudolf Linder
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of DK1187601T3 publication Critical patent/DK1187601T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK00935151T 1999-06-07 2000-05-31 Hidtil ukendt præparat og administrationsform som omfatter en syrelabil protonpumpeinhibitor DK1187601T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99110865 1999-06-07
PCT/EP2000/004958 WO2000074654A1 (en) 1999-06-07 2000-05-31 Novel preparation and administration form comprising an acid-labile active compound

Publications (1)

Publication Number Publication Date
DK1187601T3 true DK1187601T3 (da) 2005-11-21

Family

ID=8238296

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00935151T DK1187601T3 (da) 1999-06-07 2000-05-31 Hidtil ukendt præparat og administrationsform som omfatter en syrelabil protonpumpeinhibitor

Country Status (31)

Country Link
US (3) US7794752B1 (da)
EP (2) EP1187601B1 (da)
JP (1) JP4980527B2 (da)
KR (1) KR100833633B1 (da)
CN (1) CN1361683A (da)
AT (1) ATE300285T1 (da)
AU (1) AU775995B2 (da)
BG (1) BG106165A (da)
BR (1) BR0011347A (da)
CA (1) CA2376202C (da)
CZ (1) CZ20014405A3 (da)
DE (1) DE60021570T2 (da)
DK (1) DK1187601T3 (da)
EA (2) EA006899B1 (da)
EE (1) EE200100660A (da)
ES (1) ES2246238T3 (da)
HK (1) HK1046643A1 (da)
HR (1) HRP20020006A2 (da)
HU (1) HUP0201637A3 (da)
IL (2) IL146504A0 (da)
MX (1) MXPA01012659A (da)
NO (1) NO20015980L (da)
PL (1) PL352882A1 (da)
PT (1) PT1187601E (da)
SI (1) SI1187601T1 (da)
SK (1) SK285247B6 (da)
TR (1) TR200103527T2 (da)
UA (1) UA74339C2 (da)
WO (1) WO2000074654A1 (da)
YU (1) YU86001A (da)
ZA (1) ZA200110000B (da)

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DE60021570T2 (de) 2006-05-24
ATE300285T1 (de) 2005-08-15
KR100833633B1 (ko) 2008-05-30
US7785630B2 (en) 2010-08-31
US20080069882A1 (en) 2008-03-20
CZ20014405A3 (cs) 2002-04-17
IL146504A0 (en) 2002-07-25
HRP20020006A2 (en) 2003-04-30
SK285247B6 (sk) 2006-09-07
IL146504A (en) 2007-02-11
US7790198B2 (en) 2010-09-07
MXPA01012659A (es) 2003-09-04
DE60021570D1 (de) 2005-09-01
EP1187601A1 (en) 2002-03-20
EE200100660A (et) 2003-04-15
BR0011347A (pt) 2002-03-19
CA2376202C (en) 2008-11-18
HUP0201637A2 (hu) 2002-11-28
CN1361683A (zh) 2002-07-31
EA200401241A1 (ru) 2005-02-24
PT1187601E (pt) 2005-11-30
HK1046643A1 (zh) 2003-01-24
EP1187601B1 (en) 2005-07-27
EA200101266A1 (ru) 2002-06-27
AU5074100A (en) 2000-12-28
NO20015980L (no) 2002-01-23
YU86001A (sh) 2004-07-15
BG106165A (bg) 2002-09-30
ZA200110000B (en) 2002-12-24
CA2376202A1 (en) 2000-12-14
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JP2003501377A (ja) 2003-01-14
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UA74339C2 (uk) 2005-12-15
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US20060127477A1 (en) 2006-06-15
AU775995B2 (en) 2004-08-19
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SK18022001A3 (sk) 2002-04-04
KR20020011997A (ko) 2002-02-09
EA005803B1 (ru) 2005-06-30
PL352882A1 (en) 2003-09-22
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US7794752B1 (en) 2010-09-14
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JP4980527B2 (ja) 2012-07-18
EA006899B1 (ru) 2006-04-28

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