DK1225174T3 - Vandfri mirtazapinkrystaller og fremgangsmåde til fremstilling deraf - Google Patents

Vandfri mirtazapinkrystaller og fremgangsmåde til fremstilling deraf

Info

Publication number: DK1225174T3
Authority: DK; Denmark
Prior art keywords: crystals; anhydrous mirtazapine; mirtazapine crystals; preparation; anhydrous
Prior art date: 1999-11-24

Application number

DK00962908T

Other languages

Danish (da)

English (en)

Inventor

Eiichi Iishi

Yoshiyuki Imamiya

Original Assignee

Sumika Fine Chemicals Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-24

Filing date

2000-09-28

Publication date

2004-07-05

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26574376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1225174(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-09-28 Application filed by Sumika Fine Chemicals Co Ltd filed Critical Sumika Fine Chemicals Co Ltd

2004-07-05 Application granted granted Critical

2004-07-05 Publication of DK1225174T3 publication Critical patent/DK1225174T3/da

Links

239000013078 crystal Substances 0.000 title abstract 6
229960001785 mirtazapine Drugs 0.000 title abstract 4
RONZAEMNMFQXRA-UHFFFAOYSA-N mirtazapine Chemical compound C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 RONZAEMNMFQXRA-UHFFFAOYSA-N 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 abstract 3
230000001430 anti-depressive effect Effects 0.000 abstract 1
239000000935 antidepressant agent Substances 0.000 abstract 1
229940005513 antidepressants Drugs 0.000 abstract 1
MHSHMTBXVDLHCQ-UHFFFAOYSA-N mirtazapine hydrate Chemical compound O.C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 MHSHMTBXVDLHCQ-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK00962908T 1999-11-24 2000-09-28 Vandfri mirtazapinkrystaller og fremgangsmåde til fremstilling deraf DK1225174T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP33304999		1999-11-24
JP2000067476		2000-03-10
PCT/JP2000/004835 WO2001038329A1 (en)	1999-11-24	2000-07-19	Anhydrous mirtazapine crystals and process for producing the same
PCT/JP2000/006687 WO2001038330A1 (en)	1999-11-24	2000-09-28	Anhydrous mirtazapine crystals and process for the production thereof

Publications (1)

Publication Number	Publication Date
DK1225174T3 true DK1225174T3 (da)	2004-07-05

Family

ID=26574376

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00962908T DK1225174T3 (da)	1999-11-24	2000-09-28	Vandfri mirtazapinkrystaller og fremgangsmåde til fremstilling deraf

Country Status (11)

Country	Link
US (3)	US6552189B2 (de)
EP (1)	EP1225174B2 (de)
JP (1)	JP3699680B2 (de)
AT (1)	ATE261966T1 (de)
AU (2)	AU6019900A (de)
CA (1)	CA2370376C (de)
DE (1)	DE60009117T2 (de)
DK (1)	DK1225174T3 (de)
ES (1)	ES2214318T5 (de)
PT (1)	PT1225174E (de)
WO (2)	WO2001038329A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001038329A1 (en) *	1999-11-24	2001-05-31	Sumika Fine Chemicals Co., Ltd.	Anhydrous mirtazapine crystals and process for producing the same
US7838029B1 (en) *	2003-07-31	2010-11-23	Watson Laboratories, Inc.	Mirtazapine solid dosage forms
EP1689371A2 (de) *	2003-11-25	2006-08-16	Aurobindo Pharma Limited	Pharmazeutische zusammensetzung mirtazapine enthaltend
WO2005051925A1 (ja) *	2003-11-27	2005-06-09	Ajinomoto Co., Inc.	フェニルアラニン誘導体の結晶及びその製造方法
US20060039866A1 (en) *	2004-08-20	2006-02-23	Cypress Bioscience, Inc.	Method for treating sleep-related breathing disorders
JP5192707B2 (ja) *	2007-03-22	2013-05-08	住友化学株式会社	ミルタザピンの製造方法
US8425723B2 (en) *	2007-04-05	2013-04-23	Akzo Nobel N.V.	Process for improving optical properties of paper
CA2704117C (en) *	2007-11-02	2015-11-17	Acrux Dds Pty Ltd	Transdermal delivery system
CN103520169B (zh) *	2013-10-25	2015-07-15	山东鲁药制药有限公司	米氮平片及其制备方法
WO2016138357A1 (en)	2015-02-27	2016-09-01	Kindred Biosciences, Inc.	Stimulation of appetite, management of weight loss, and treatment of anorexia in dogs and cats
JP6452575B2 (ja) *	2015-08-19	2019-01-16	株式会社トクヤマ	ミルタザピンの製造方法
JP6571497B2 (ja) *	2015-11-13	2019-09-04	株式会社トクヤマ	ミルタザピンの製造方法
JP2017088564A (ja) *	2015-11-13	2017-05-25	株式会社トクヤマ	ミルタザピンの製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL189199C (nl) *	1975-04-05	1993-02-01	Akzo Nv	Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
US4524146A (en)	1982-12-08	1985-06-18	Ciba-Geigy Corporation	Certain -2-heterocycle substituted pyrazoloquinolines
NZ230711A (en)	1988-09-23	1990-10-26	Ortho Pharma Corp	Substituted thienopyrans as antihypertensive agents
US5354763A (en)	1993-11-17	1994-10-11	American Home Products Corporation	Substituted N-heteroaryl and N-aryl-1,2-diaminocyclobutene-3,4-diones
US5468768A (en)	1994-01-06	1995-11-21	Bristol-Myers Squibb Company	Antimigraine derivatives of indolylcycloalkanylamines
JPH07247286A (ja) *	1994-01-18	1995-09-26	Sankyo Co Ltd	含窒素環状化合物の光学分割方法
US6545149B2 (en)	1999-04-19	2003-04-08	Teva Pharmaceutical Industries Ltd.	Synthesis and crystallization of piperazine ring-containing compounds
CA2368815A1 (en) *	1999-04-19	2000-10-26	Claude Singer	Novel synthesis and crystallization of piperazine ring-containing compounds
WO2001038329A1 (en) *	1999-11-24	2001-05-31	Sumika Fine Chemicals Co., Ltd.	Anhydrous mirtazapine crystals and process for producing the same
US20020072602A1 (en)	2000-07-07	2002-06-13	Claude Singer	Micronized mirtazapine
US6660730B2 (en) *	2000-11-27	2003-12-09	Sumika Fine Chemicals Co., Ltd.	Anhydrous mirtazapine and process for preparing the same

2000
- 2000-07-19 WO PCT/JP2000/004835 patent/WO2001038329A1/ja not_active Ceased
- 2000-07-19 AU AU60199/00A patent/AU6019900A/en not_active Abandoned
- 2000-09-28 CA CA002370376A patent/CA2370376C/en not_active Expired - Fee Related
- 2000-09-28 EP EP00962908A patent/EP1225174B2/de not_active Expired - Lifetime
- 2000-09-28 AT AT00962908T patent/ATE261966T1/de not_active IP Right Cessation
- 2000-09-28 DK DK00962908T patent/DK1225174T3/da active
- 2000-09-28 WO PCT/JP2000/006687 patent/WO2001038330A1/ja not_active Ceased
- 2000-09-28 PT PT00962908T patent/PT1225174E/pt unknown
- 2000-09-28 AU AU74471/00A patent/AU763502B2/en not_active Ceased
- 2000-09-28 DE DE60009117T patent/DE60009117T2/de not_active Expired - Lifetime
- 2000-09-28 ES ES00962908T patent/ES2214318T5/es not_active Expired - Lifetime
- 2000-09-28 JP JP2001540093A patent/JP3699680B2/ja not_active Expired - Lifetime
2002
- 2002-01-10 US US10/041,495 patent/US6552189B2/en not_active Expired - Fee Related
2003
- 2003-01-07 US US10/337,277 patent/US6723845B2/en not_active Expired - Fee Related
- 2003-12-24 US US10/743,740 patent/US7297790B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU7447100A (en)	2001-06-04
JP3699680B2 (ja)	2005-09-28
ES2214318T5 (es)	2010-10-15
US6723845B2 (en)	2004-04-20
PT1225174E (pt)	2004-05-31
EP1225174B1 (de)	2004-03-17
EP1225174A1 (de)	2002-07-24
US20040138447A1 (en)	2004-07-15
WO2001038330A1 (en)	2001-05-31
US6552189B2 (en)	2003-04-22
WO2001038329A1 (en)	2001-05-31
AU763502B2 (en)	2003-07-24
US7297790B2 (en)	2007-11-20
ATE261966T1 (de)	2004-04-15
DE60009117D1 (de)	2004-04-22
US20030130504A1 (en)	2003-07-10
EP1225174A4 (de)	2002-10-23
AU6019900A (en)	2001-06-04
US20020103372A1 (en)	2002-08-01
EP1225174B2 (de)	2010-06-02
CA2370376A1 (en)	2001-05-31
DE60009117T2 (de)	2004-10-21
ES2214318T3 (es)	2004-09-16
CA2370376C (en)	2005-08-02

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