DK1228028T3 - Hydroxyicosatetraenoatsalte, præparater og fremgangsmåder til anvendelse til behandling af öjentörhedslidelser - Google Patents

Hydroxyicosatetraenoatsalte, præparater og fremgangsmåder til anvendelse til behandling af öjentörhedslidelser

Info

Publication number
DK1228028T3
DK1228028T3 DK00972338T DK00972338T DK1228028T3 DK 1228028 T3 DK1228028 T3 DK 1228028T3 DK 00972338 T DK00972338 T DK 00972338T DK 00972338 T DK00972338 T DK 00972338T DK 1228028 T3 DK1228028 T3 DK 1228028T3
Authority
DK
Denmark
Prior art keywords
hydroxyicosatetraenoate
preparations
salts
treatment
methods
Prior art date
Application number
DK00972338T
Other languages
English (en)
Inventor
L Wayne Schneider
Raymond E Conrow
Daniel A Gamache
Terri Pasquine
John M Yanni
Haresh G Bhagat
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of DK1228028T3 publication Critical patent/DK1228028T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK00972338T 1999-11-09 2000-10-23 Hydroxyicosatetraenoatsalte, præparater og fremgangsmåder til anvendelse til behandling af öjentörhedslidelser DK1228028T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16437099P 1999-11-09 1999-11-09
US16438299P 1999-11-09 1999-11-09
US16438499P 1999-11-09 1999-11-09

Publications (1)

Publication Number Publication Date
DK1228028T3 true DK1228028T3 (da) 2005-11-14

Family

ID=27389012

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00972338T DK1228028T3 (da) 1999-11-09 2000-10-23 Hydroxyicosatetraenoatsalte, præparater og fremgangsmåder til anvendelse til behandling af öjentörhedslidelser

Country Status (20)

Country Link
US (1) US6429227B1 (da)
EP (1) EP1228028B1 (da)
JP (1) JP2003513949A (da)
KR (1) KR20020050240A (da)
CN (1) CN1387503A (da)
AR (1) AR032607A1 (da)
AT (1) ATE301630T1 (da)
AU (1) AU776187B2 (da)
BR (1) BR0015436A (da)
CA (1) CA2388044A1 (da)
DE (1) DE60021908T2 (da)
DK (1) DK1228028T3 (da)
ES (1) ES2242643T3 (da)
HK (1) HK1045302B (da)
MX (1) MXPA02004701A (da)
PL (1) PL356093A1 (da)
PT (1) PT1228028E (da)
TR (1) TR200201250T2 (da)
TW (1) TWI283176B (da)
WO (1) WO2001034549A1 (da)

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US20020077358A1 (en) * 2000-10-23 2002-06-20 Alcon Universal Ltd. Use of hydroperoxyeicosatetraenoic acid derivatives following refractive surgery
WO2003030894A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
WO2003030892A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
AU2003221707A1 (en) * 2002-06-14 2003-12-31 Alcon, Inc. Topical use of hydroxyeicosatetraenoic acid compounds to treat psoriasis
WO2003105831A1 (en) * 2002-06-14 2003-12-24 Alcon, Inc. Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders
WO2003105823A1 (en) * 2002-06-14 2003-12-24 Alcon, Inc. Use of hydroxyeicosatetraenoic acid compounds to treat dry mouth
AU2003221715A1 (en) * 2002-06-14 2003-12-31 Alcon, Inc. Use of hydroxyeicosatetraenoic acid compounds to treat vaginal dryness
JP2006502183A (ja) * 2002-09-20 2006-01-19 アルコン，インコーポレイテッド ドライアイ障害の処置のためのサイトカイン合成インヒビターの使用
PT1551417E (pt) * 2002-10-18 2008-10-31 Aqueous Pharma Ltd Formulação de lágrimas com três camadas
US20050187192A1 (en) * 2004-02-20 2005-08-25 Kucera Pharmaceutical Company Phospholipids for the treatment of infection by togaviruses, herpes viruses and coronaviruses
CN1984663A (zh) 2004-03-29 2007-06-20 南佛罗里达大学 用曲西瑞宾和相关化合物有效治疗肿瘤和癌症
KR100642425B1 (ko) * 2004-07-09 2006-11-03 (유) 이도건설 친수호안 구조
US7820639B2 (en) * 2004-10-01 2010-10-26 Lindstrom Richard L Ophthalmic compositions including lubricant, deturgescent agent, and glycosaminoglycan and methods of using the same
US7638142B2 (en) * 2005-10-12 2009-12-29 Vitamin Science, Inc. Therapeutic composition for the treatment of dry eye syndrome
JP5670200B2 (ja) * 2008-12-02 2015-02-18 ロート製薬株式会社 眼科用組成物
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
AU2012209184B2 (en) 2011-01-26 2017-06-15 Allergan, Inc. Androgen composition for treating an opthalmic condition
IL212725A (en) * 2011-05-05 2016-06-30 Resdevco Res And Dev Co Glycerol Preparation for Non-surgical Conjunctivochalysis
JP6353365B2 (ja) * 2012-09-27 2018-07-04 千寿製薬株式会社 水性液剤
DK2950783T3 (da) * 2013-02-01 2019-07-22 Allergan Inc Kunstige tårer omfattende natriumhyaluronat og carboxymethylcellulose
ES2727387T3 (es) * 2013-11-15 2019-10-15 Ds Biopharma Ltd Sal de lisina de ácido 15-hidroxi-8(Z),11(Z),13(E)-eicosatrienoico
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases
IT202300019488A1 (it) * 2023-09-21 2025-03-21 D&V Farma Soc A Responsabilita Limitata Composizioni, usi e metodi per il trattamento della sindrome dell’occhio secco o per promuovere la guarigione delle ferite corneali

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US4131651A (en) 1977-10-25 1978-12-26 Barnes-Hind Pharmaceuticals, Inc. Treatment of dry eye
US4409205A (en) 1979-03-05 1983-10-11 Cooper Laboratories, Inc. Ophthalmic solution
US4370325A (en) 1979-03-30 1983-01-25 Dermik Laboratories Pharmaceutical compositions and method of treatment
AU546872B2 (en) 1982-06-16 1985-09-26 Unilever Plc Skin treatment compositions containing a fatty acid or ester
US4421748A (en) 1982-07-13 1983-12-20 Trager Seymour F Artificial tear aid
GB8319073D0 (en) 1983-07-14 1983-08-17 Efamol Ltd Fatty acid compositions
US4868154A (en) 1986-02-19 1989-09-19 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with melanocyte stimulating hormones
US4753945A (en) 1986-02-19 1988-06-28 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with phosphodiesterase inhibitors
US4883658A (en) 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4744980A (en) 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US4818537A (en) 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
US4966773A (en) 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
US4914088A (en) 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US5278151A (en) 1987-04-02 1994-01-11 Ocular Research Of Boston, Inc. Dry eye treatment solution
US4921644A (en) 1988-02-29 1990-05-01 Technology Unlimited, Inc. Mucin directed lipsome
US4906467A (en) 1988-03-24 1990-03-06 New York Medical College Novel, long-duration treatment for glaucoma
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US5064655A (en) 1989-02-24 1991-11-12 Liposome Technology, Inc. Liposome gel composition and method
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US5696166A (en) 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
WO1998016240A1 (en) 1996-10-15 1998-04-23 The Liposome Company, Inc. Peptide-lipid conjugates, liposomes and liposomal drug delivery
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Also Published As

Publication number Publication date
HK1045302A1 (en) 2002-11-22
CA2388044A1 (en) 2001-05-17
PL356093A1 (en) 2004-06-14
EP1228028A1 (en) 2002-08-07
HK1045302B (en) 2005-10-14
DE60021908T2 (de) 2006-04-06
AU1101401A (en) 2001-06-06
PT1228028E (pt) 2005-10-31
KR20020050240A (ko) 2002-06-26
WO2001034549A1 (en) 2001-05-17
ES2242643T3 (es) 2005-11-16
US6429227B1 (en) 2002-08-06
CN1387503A (zh) 2002-12-25
DE60021908D1 (de) 2005-09-15
JP2003513949A (ja) 2003-04-15
BR0015436A (pt) 2002-07-16
MXPA02004701A (es) 2004-09-10
ATE301630T1 (de) 2005-08-15
AR032607A1 (es) 2003-11-19
TR200201250T2 (tr) 2002-09-23
TWI283176B (en) 2007-07-01
EP1228028B1 (en) 2005-08-10
AU776187B2 (en) 2004-09-02

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