TR200201250T2 - Hidroksieikosatetraenoat tuzları, bileşimleri ve bunların göz kuruması bozukluklarının iyileştirilmesinde kullanım yöntemleri. - Google Patents
Hidroksieikosatetraenoat tuzları, bileşimleri ve bunların göz kuruması bozukluklarının iyileştirilmesinde kullanım yöntemleri.Info
- Publication number
- TR200201250T2 TR200201250T2 TR2002/01250T TR200201250T TR200201250T2 TR 200201250 T2 TR200201250 T2 TR 200201250T2 TR 2002/01250 T TR2002/01250 T TR 2002/01250T TR 200201250 T TR200201250 T TR 200201250T TR 200201250 T2 TR200201250 T2 TR 200201250T2
- Authority
- TR
- Turkey
- Prior art keywords
- compositions
- salts
- methods
- hydroxyiecosatetraenoate
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
HETE tuzlari, HETE tuzlarinin hazirlanisi, kararli ve sonuç verir HETE bilesimlerinin hazirlanisi, göz kurumasinin iyilestirilmesi için HETE bilesimleri ve yöntemler anlatilmistir.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16438499P | 1999-11-09 | 1999-11-09 | |
| US16438299P | 1999-11-09 | 1999-11-09 | |
| US16437099P | 1999-11-09 | 1999-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200201250T2 true TR200201250T2 (tr) | 2002-09-23 |
Family
ID=27389012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2002/01250T TR200201250T2 (tr) | 1999-11-09 | 2000-10-23 | Hidroksieikosatetraenoat tuzları, bileşimleri ve bunların göz kuruması bozukluklarının iyileştirilmesinde kullanım yöntemleri. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6429227B1 (tr) |
| EP (1) | EP1228028B1 (tr) |
| JP (1) | JP2003513949A (tr) |
| KR (1) | KR20020050240A (tr) |
| CN (1) | CN1387503A (tr) |
| AR (1) | AR032607A1 (tr) |
| AT (1) | ATE301630T1 (tr) |
| AU (1) | AU776187B2 (tr) |
| BR (1) | BR0015436A (tr) |
| CA (1) | CA2388044A1 (tr) |
| DE (1) | DE60021908T2 (tr) |
| DK (1) | DK1228028T3 (tr) |
| ES (1) | ES2242643T3 (tr) |
| HK (1) | HK1045302B (tr) |
| MX (1) | MXPA02004701A (tr) |
| PL (1) | PL356093A1 (tr) |
| PT (1) | PT1228028E (tr) |
| TR (1) | TR200201250T2 (tr) |
| TW (1) | TWI283176B (tr) |
| WO (1) | WO2001034549A1 (tr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020077358A1 (en) * | 2000-10-23 | 2002-06-20 | Alcon Universal Ltd. | Use of hydroperoxyeicosatetraenoic acid derivatives following refractive surgery |
| WO2003030892A1 (en) * | 2001-10-11 | 2003-04-17 | Alcon, Inc. | Methods for treating dry eye |
| US20030109508A1 (en) * | 2001-10-11 | 2003-06-12 | Alcon, Inc. | Methods for treating dry eye |
| US20030236284A1 (en) * | 2002-06-14 | 2003-12-25 | Alcon, Inc. | Use of hydroxyeicosatetraenoic acid compounds to treat vaginal dryness |
| WO2003105824A1 (en) * | 2002-06-14 | 2003-12-24 | Alcon, Inc. | Topical use of hydroxyeicosatetraenoic acid compounds to treat psoriasis |
| AU2003235452A1 (en) * | 2002-06-14 | 2003-12-31 | Alcon, Inc. | Use of hydroxyeicosatetraenoic acid compounds to treat dry mouth |
| US6825232B2 (en) * | 2002-06-14 | 2004-11-30 | Alcon, Inc. | Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders |
| BR0314603A (pt) * | 2002-09-20 | 2005-07-26 | Alcon Inc | Uso de inibidores da sìntese de citoquina para o tratamento de distúrbios de olhos secos |
| US7758883B2 (en) * | 2002-10-18 | 2010-07-20 | Aqueous Pharma Limited | Three layer artificial tear formulation |
| US20050187192A1 (en) * | 2004-02-20 | 2005-08-25 | Kucera Pharmaceutical Company | Phospholipids for the treatment of infection by togaviruses, herpes viruses and coronaviruses |
| CA2561513C (en) | 2004-03-29 | 2019-02-26 | University Of South Florida | Effective treatment of tumors and cancer with triciribine and related compounds |
| KR100642425B1 (ko) * | 2004-07-09 | 2006-11-03 | (유) 이도건설 | 친수호안 구조 |
| WO2006044155A2 (en) * | 2004-10-01 | 2006-04-27 | Lindstrom Richard L | Ophthalmic compositions including lubricant, deturgescent agent, and glycosaminoglycan and methods of using the same |
| US7638142B2 (en) * | 2005-10-12 | 2009-12-29 | Vitamin Science, Inc. | Therapeutic composition for the treatment of dry eye syndrome |
| US8669241B2 (en) * | 2008-12-02 | 2014-03-11 | Rohto Pharmaceutical Co., Ltd. | Ophthalmic composition |
| GB0907413D0 (en) | 2009-04-29 | 2009-06-10 | Equateq Ltd | Novel methods |
| HUE037660T2 (hu) * | 2011-01-26 | 2018-09-28 | Allergan Inc | Androgén készítmény szembetegség kezelésére |
| IL212725A (en) * | 2011-05-05 | 2016-06-30 | Resdevco Res And Dev Co | Glycerol Preparation for Non-surgical Conjunctivochalysis |
| JP6353365B2 (ja) * | 2012-09-27 | 2018-07-04 | 千寿製薬株式会社 | 水性液剤 |
| LT2950783T (lt) * | 2013-02-01 | 2019-10-25 | Allergan Inc | Dirbtinės ašaros, kurių sudėtyje yra natrio hialuronato ir karboksimetilceliuliozės |
| US10017453B2 (en) * | 2013-11-15 | 2018-07-10 | Ds Biopharma Limited | Pharmaceutically acceptable salts of fatty acids |
| US20210315851A1 (en) | 2020-04-03 | 2021-10-14 | Afimmune Limited | Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases |
| IT202300019488A1 (it) * | 2023-09-21 | 2025-03-21 | D&V Farma Soc A Responsabilita Limitata | Composizioni, usi e metodi per il trattamento della sindrome dell’occhio secco o per promuovere la guarigione delle ferite corneali |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3991759A (en) | 1975-10-28 | 1976-11-16 | Alza Corporation | Method and therapeutic system for treating aqueous deficient dry eye |
| US4131651A (en) | 1977-10-25 | 1978-12-26 | Barnes-Hind Pharmaceuticals, Inc. | Treatment of dry eye |
| US4409205A (en) | 1979-03-05 | 1983-10-11 | Cooper Laboratories, Inc. | Ophthalmic solution |
| US4370325A (en) | 1979-03-30 | 1983-01-25 | Dermik Laboratories | Pharmaceutical compositions and method of treatment |
| AU546872B2 (en) | 1982-06-16 | 1985-09-26 | Unilever Plc | Skin treatment compositions containing a fatty acid or ester |
| US4421748A (en) | 1982-07-13 | 1983-12-20 | Trager Seymour F | Artificial tear aid |
| GB8319073D0 (en) | 1983-07-14 | 1983-08-17 | Efamol Ltd | Fatty acid compositions |
| US4868154A (en) | 1986-02-19 | 1989-09-19 | Eye Research Institute Of Retina Foundation | Stimulation of tear secretion with melanocyte stimulating hormones |
| US4753945A (en) | 1986-02-19 | 1988-06-28 | Eye Research Institute Of Retina Foundation | Stimulation of tear secretion with phosphodiesterase inhibitors |
| US4744980A (en) | 1986-04-28 | 1988-05-17 | Holly Frank J | Ophthalmic solution for treatment of dry eye syndrome |
| US4883658A (en) | 1986-04-28 | 1989-11-28 | Holly Frank J | Ophthalmic solution for treatment of dry-eye syndrome |
| US4818537A (en) | 1986-10-21 | 1989-04-04 | Liposome Technology, Inc. | Liposome composition for treating dry eye |
| US4966773A (en) | 1986-11-25 | 1990-10-30 | Alcon Laboratories, Inc. | Topical ophthalmic compositions containing microfine retinoid particles |
| US5278151A (en) | 1987-04-02 | 1994-01-11 | Ocular Research Of Boston, Inc. | Dry eye treatment solution |
| US4914088A (en) | 1987-04-02 | 1990-04-03 | Thomas Glonek | Dry eye treatment solution and method |
| US4921644A (en) | 1988-02-29 | 1990-05-01 | Technology Unlimited, Inc. | Mucin directed lipsome |
| US4906467A (en) | 1988-03-24 | 1990-03-06 | New York Medical College | Novel, long-duration treatment for glaucoma |
| US4923700A (en) | 1988-06-03 | 1990-05-08 | Kaufman Herbert E | Artificial tear suspension |
| US5064655A (en) | 1989-02-24 | 1991-11-12 | Liposome Technology, Inc. | Liposome gel composition and method |
| US5075104A (en) | 1989-03-31 | 1991-12-24 | Alcon Laboratories, Inc. | Ophthalmic carboxy vinyl polymer gel for dry eye syndrome |
| US5174988A (en) | 1989-07-27 | 1992-12-29 | Scientific Development & Research, Inc. | Phospholipid delivery system |
| WO1991012808A1 (en) | 1990-02-22 | 1991-09-05 | Macnaught Pty Limited | Artificial tears |
| US5041434A (en) | 1991-08-17 | 1991-08-20 | Virginia Lubkin | Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application |
| ZA912797B (en) | 1990-05-29 | 1992-12-30 | Boston Ocular Res | Dry eye treatment process and solution |
| EP0459148B1 (en) | 1990-05-29 | 1996-01-03 | Ocular Research Of Boston Inc. | Dry eye treatment composition |
| US5102670A (en) | 1990-09-14 | 1992-04-07 | Abraham Nader G | Method for treating eye disorders by reducing 12(r)-hydroxyeicosatetraenoic acid and 12(r)-dihydroxyeicosatrienoic acid levels |
| DK0495421T3 (da) | 1991-01-15 | 1996-12-09 | Alcon Lab Inc | Anvendelse af carragenaner i topiske ophthalmiske sammensætninger |
| ZA927277B (en) | 1991-10-02 | 1993-05-19 | Boston Ocular Res | Dry eye treatment process and solution. |
| EP0546728A3 (en) | 1991-12-13 | 1993-09-08 | Alcon Laboratories Inc | Physiological tear compositions and methods for their preparation |
| EP0643581B1 (en) | 1992-04-21 | 1999-10-20 | The Schepens Eye Research Institute, Inc. | Ocular androgen therapy in sjögren's syndrome |
| US5290572A (en) | 1992-08-06 | 1994-03-01 | Deo Corporation | Opthalmic composition for treating dry eye |
| US5358706A (en) | 1992-09-30 | 1994-10-25 | Union Carbide Chemicals & Plastics Technology Corporation | Muco-adhesive polymers |
| US5455265A (en) | 1993-02-11 | 1995-10-03 | Allergan, Inc. | Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors |
| US5389383A (en) | 1993-06-18 | 1995-02-14 | Allergan, Inc. | Method for treating hypoxia-associated ocular complications |
| US5696166A (en) | 1995-10-31 | 1997-12-09 | Yanni; John M. | Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders |
| EP0964690B1 (en) | 1996-10-15 | 2003-07-09 | The Liposome Company, Inc. | Peptide-lipid conjugates, liposomes and liposomal drug delivery |
| US5800807A (en) | 1997-01-29 | 1998-09-01 | Bausch & Lomb Incorporated | Ophthalmic compositions including glycerin and propylene glycol |
| JP2002538124A (ja) | 1999-03-01 | 2002-11-12 | ヴィスタ サイエンティフィック エルエルシー | ムチンを含む眼科用調合物 |
-
2000
- 2000-10-23 KR KR1020027004608A patent/KR20020050240A/ko not_active Ceased
- 2000-10-23 BR BR0015436-9A patent/BR0015436A/pt not_active IP Right Cessation
- 2000-10-23 WO PCT/US2000/029227 patent/WO2001034549A1/en not_active Ceased
- 2000-10-23 AU AU11014/01A patent/AU776187B2/en not_active Ceased
- 2000-10-23 ES ES00972338T patent/ES2242643T3/es not_active Expired - Lifetime
- 2000-10-23 DE DE60021908T patent/DE60021908T2/de not_active Expired - Fee Related
- 2000-10-23 CN CN00815338A patent/CN1387503A/zh active Pending
- 2000-10-23 PT PT00972338T patent/PT1228028E/pt unknown
- 2000-10-23 CA CA002388044A patent/CA2388044A1/en not_active Abandoned
- 2000-10-23 DK DK00972338T patent/DK1228028T3/da active
- 2000-10-23 PL PL00356093A patent/PL356093A1/xx unknown
- 2000-10-23 AT AT00972338T patent/ATE301630T1/de not_active IP Right Cessation
- 2000-10-23 TR TR2002/01250T patent/TR200201250T2/tr unknown
- 2000-10-23 US US09/694,615 patent/US6429227B1/en not_active Expired - Lifetime
- 2000-10-23 JP JP2001536500A patent/JP2003513949A/ja not_active Withdrawn
- 2000-10-23 MX MXPA02004701A patent/MXPA02004701A/es active IP Right Grant
- 2000-10-23 HK HK02106795.2A patent/HK1045302B/en not_active IP Right Cessation
- 2000-10-23 EP EP00972338A patent/EP1228028B1/en not_active Expired - Lifetime
- 2000-11-08 AR ARP000105865A patent/AR032607A1/es not_active Application Discontinuation
- 2000-11-08 TW TW089123630A patent/TWI283176B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1228028A1 (en) | 2002-08-07 |
| DE60021908T2 (de) | 2006-04-06 |
| CN1387503A (zh) | 2002-12-25 |
| US6429227B1 (en) | 2002-08-06 |
| MXPA02004701A (es) | 2004-09-10 |
| HK1045302A1 (en) | 2002-11-22 |
| BR0015436A (pt) | 2002-07-16 |
| KR20020050240A (ko) | 2002-06-26 |
| PL356093A1 (en) | 2004-06-14 |
| EP1228028B1 (en) | 2005-08-10 |
| DE60021908D1 (de) | 2005-09-15 |
| TWI283176B (en) | 2007-07-01 |
| WO2001034549A1 (en) | 2001-05-17 |
| ES2242643T3 (es) | 2005-11-16 |
| AR032607A1 (es) | 2003-11-19 |
| AU1101401A (en) | 2001-06-06 |
| ATE301630T1 (de) | 2005-08-15 |
| HK1045302B (en) | 2005-10-14 |
| CA2388044A1 (en) | 2001-05-17 |
| JP2003513949A (ja) | 2003-04-15 |
| PT1228028E (pt) | 2005-10-31 |
| AU776187B2 (en) | 2004-09-02 |
| DK1228028T3 (da) | 2005-11-14 |
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