DK1237575T3 - TNF-alfa-antagonist og LFA-1-antagonist til behandling af rheumatoid arthritis - Google Patents

TNF-alfa-antagonist og LFA-1-antagonist til behandling af rheumatoid arthritis

Info

Publication number
DK1237575T3
DK1237575T3 DK00986377T DK00986377T DK1237575T3 DK 1237575 T3 DK1237575 T3 DK 1237575T3 DK 00986377 T DK00986377 T DK 00986377T DK 00986377 T DK00986377 T DK 00986377T DK 1237575 T3 DK1237575 T3 DK 1237575T3
Authority
DK
Denmark
Prior art keywords
antagonist
lfa
treatment
rheumatoid arthritis
tnf alpha
Prior art date
Application number
DK00986377T
Other languages
English (en)
Inventor
Wyne Pun Lee
Daniel B Tumas
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK1237575T3 publication Critical patent/DK1237575T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
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  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
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  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Biophysics (AREA)
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DK00986377T 1999-12-14 2000-12-14 TNF-alfa-antagonist og LFA-1-antagonist til behandling af rheumatoid arthritis DK1237575T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17069699P 1999-12-14 1999-12-14
PCT/US2000/033875 WO2001043773A1 (en) 1999-12-14 2000-12-14 Tnf-alpha antagonist and lfa-1 antagonist for treating lfa-1 or tnf-alpha mediated disorder

Publications (1)

Publication Number Publication Date
DK1237575T3 true DK1237575T3 (da) 2008-12-08

Family

ID=22620900

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00986377T DK1237575T3 (da) 1999-12-14 2000-12-14 TNF-alfa-antagonist og LFA-1-antagonist til behandling af rheumatoid arthritis

Country Status (15)

Country Link
US (3) US20010031260A1 (da)
EP (1) EP1237575B1 (da)
JP (1) JP2003517022A (da)
KR (1) KR100567292B1 (da)
CN (1) CN1409639A (da)
AT (1) ATE403437T1 (da)
AU (1) AU768324B2 (da)
CA (1) CA2394862C (da)
DE (1) DE60039783D1 (da)
DK (1) DK1237575T3 (da)
ES (1) ES2311483T3 (da)
IL (1) IL149890A0 (da)
NZ (1) NZ519222A (da)
PT (1) PT1237575E (da)
WO (1) WO2001043773A1 (da)

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ES2763703T3 (es) * 2008-04-15 2020-05-29 Sarcode Bioscience Inc Antagonistas de LFA-1 tópicos utilizados en el tratamiento localizado de trastornos inmunes
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WO2011063127A1 (en) 2009-11-18 2011-05-26 University Of Medicine And Dentistry Of New Jersey Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies
PL2461700T3 (pl) * 2009-08-06 2016-11-30 Środek konserwujący do wody i pożywienia
US8378105B2 (en) * 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
US9849192B2 (en) 2009-11-18 2017-12-26 Rutgers, The State University Of New Jersey Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies
LT2611310T (lt) * 2010-08-27 2017-10-10 Anitox Corporation Antimikrobinė kompozicija
MX2014004618A (es) 2011-10-20 2014-05-27 Anitox Corp Formulaciones antimicrobianas con acido pelargonico.
ES2859788T3 (es) 2011-11-30 2021-10-04 Anitox Corp Mezcla antimicrobiana de aldehídos, ácidos orgánicos y ésteres de ácidos orgánicos
SI3715345T1 (sl) 2012-07-25 2024-07-31 Bausch + Lomb Ireland Limited Priprava zaviralca lfa-1
WO2014046631A1 (en) 2012-09-19 2014-03-27 Tezcaner Aysen CONTROLED DRUG DELIVERY SYSTEMS FOR ANTI-TNF-α
US9549993B2 (en) 2012-10-02 2017-01-24 Rutgers, The State University Of New Jersey Specific delivery of toxins conjugated with antibodies to activate matripase
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RU2613056C1 (ru) * 2016-03-14 2017-03-15 Государственное бюджетное образовательное учреждение высшего профессионального образования "Южно-Уральский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО ЮУГМУ Минздрава России) Способ прогнозирования развития увеита у детей с ювенильным идиопатическим артритом
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EP1237575A1 (en) 2002-09-11
PT1237575E (pt) 2008-11-17
US20050214291A1 (en) 2005-09-29
DE60039783D1 (de) 2008-09-18
CA2394862A1 (en) 2001-06-21
KR100567292B1 (ko) 2006-04-04
US20080031875A1 (en) 2008-02-07
US20010031260A1 (en) 2001-10-18
EP1237575B1 (en) 2008-08-06
AU5439701A (en) 2001-06-25
JP2003517022A (ja) 2003-05-20
ATE403437T1 (de) 2008-08-15
KR20020068372A (ko) 2002-08-27
NZ519222A (en) 2004-04-30
CA2394862C (en) 2011-10-11
CN1409639A (zh) 2003-04-09
AU768324B2 (en) 2003-12-11
ES2311483T3 (es) 2009-02-16
IL149890A0 (en) 2002-11-10
WO2001043773A1 (en) 2001-06-21

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