PT1237575E - Antagonista de tnf-alfa e antagonista de lfa-1 para tratar a artrite reumatóide - Google Patents

Antagonista de tnf-alfa e antagonista de lfa-1 para tratar a artrite reumatóide Download PDF

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Publication number
PT1237575E
PT1237575E PT00986377T PT00986377T PT1237575E PT 1237575 E PT1237575 E PT 1237575E PT 00986377 T PT00986377 T PT 00986377T PT 00986377 T PT00986377 T PT 00986377T PT 1237575 E PT1237575 E PT 1237575E
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PT
Portugal
Prior art keywords
antagonist
lfa
tnf
alpha
rheumatoid arthritis
Prior art date
Application number
PT00986377T
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English (en)
Inventor
Wyne Pun Lee
Daniel B Tumas
Original Assignee
Genentech Inc
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Publication of PT1237575E publication Critical patent/PT1237575E/pt

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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Molecular Biology (AREA)
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  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
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PT00986377T 1999-12-14 2000-12-14 Antagonista de tnf-alfa e antagonista de lfa-1 para tratar a artrite reumatóide PT1237575E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17069699P 1999-12-14 1999-12-14

Publications (1)

Publication Number Publication Date
PT1237575E true PT1237575E (pt) 2008-11-17

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PT00986377T PT1237575E (pt) 1999-12-14 2000-12-14 Antagonista de tnf-alfa e antagonista de lfa-1 para tratar a artrite reumatóide

Country Status (15)

Country Link
US (3) US20010031260A1 (pt)
EP (1) EP1237575B1 (pt)
JP (1) JP2003517022A (pt)
KR (1) KR100567292B1 (pt)
CN (1) CN1409639A (pt)
AT (1) ATE403437T1 (pt)
AU (1) AU768324B2 (pt)
CA (1) CA2394862C (pt)
DE (1) DE60039783D1 (pt)
DK (1) DK1237575T3 (pt)
ES (1) ES2311483T3 (pt)
IL (1) IL149890A0 (pt)
NZ (1) NZ519222A (pt)
PT (1) PT1237575E (pt)
WO (1) WO2001043773A1 (pt)

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WO2011063127A1 (en) 2009-11-18 2011-05-26 University Of Medicine And Dentistry Of New Jersey Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies
PL2461700T3 (pl) * 2009-08-06 2016-11-30 Środek konserwujący do wody i pożywienia
US8378105B2 (en) * 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
US9849192B2 (en) 2009-11-18 2017-12-26 Rutgers, The State University Of New Jersey Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies
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SI3715345T1 (sl) 2012-07-25 2024-07-31 Bausch + Lomb Ireland Limited Priprava zaviralca lfa-1
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US9549993B2 (en) 2012-10-02 2017-01-24 Rutgers, The State University Of New Jersey Specific delivery of toxins conjugated with antibodies to activate matripase
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US20050214291A1 (en) 2005-09-29
DE60039783D1 (de) 2008-09-18
CA2394862A1 (en) 2001-06-21
KR100567292B1 (ko) 2006-04-04
US20080031875A1 (en) 2008-02-07
US20010031260A1 (en) 2001-10-18
EP1237575B1 (en) 2008-08-06
AU5439701A (en) 2001-06-25
DK1237575T3 (da) 2008-12-08
JP2003517022A (ja) 2003-05-20
ATE403437T1 (de) 2008-08-15
KR20020068372A (ko) 2002-08-27
NZ519222A (en) 2004-04-30
CA2394862C (en) 2011-10-11
CN1409639A (zh) 2003-04-09
AU768324B2 (en) 2003-12-11
ES2311483T3 (es) 2009-02-16
IL149890A0 (en) 2002-11-10
WO2001043773A1 (en) 2001-06-21

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