PT1237575E - Antagonista de tnf-alfa e antagonista de lfa-1 para tratar a artrite reumatóide - Google Patents

Antagonista de tnf-alfa e antagonista de lfa-1 para tratar a artrite reumatóide Download PDF

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Publication number
PT1237575E
PT1237575E PT00986377T PT00986377T PT1237575E PT 1237575 E PT1237575 E PT 1237575E PT 00986377 T PT00986377 T PT 00986377T PT 00986377 T PT00986377 T PT 00986377T PT 1237575 E PT1237575 E PT 1237575E
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PT
Portugal
Prior art keywords
antagonist
lfa
tnf
alpha
rheumatoid arthritis
Prior art date
Application number
PT00986377T
Other languages
English (en)
Inventor
Wyne Pun Lee
Daniel B Tumas
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of PT1237575E publication Critical patent/PT1237575E/pt

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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Proteomics, Peptides & Aminoacids (AREA)
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PT00986377T 1999-12-14 2000-12-14 Antagonista de tnf-alfa e antagonista de lfa-1 para tratar a artrite reumatóide PT1237575E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17069699P 1999-12-14 1999-12-14

Publications (1)

Publication Number Publication Date
PT1237575E true PT1237575E (pt) 2008-11-17

Family

ID=22620900

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00986377T PT1237575E (pt) 1999-12-14 2000-12-14 Antagonista de tnf-alfa e antagonista de lfa-1 para tratar a artrite reumatóide

Country Status (15)

Country Link
US (3) US20010031260A1 (pt)
EP (1) EP1237575B1 (pt)
JP (1) JP2003517022A (pt)
KR (1) KR100567292B1 (pt)
CN (1) CN1409639A (pt)
AT (1) ATE403437T1 (pt)
AU (1) AU768324B2 (pt)
CA (1) CA2394862C (pt)
DE (1) DE60039783D1 (pt)
DK (1) DK1237575T3 (pt)
ES (1) ES2311483T3 (pt)
IL (1) IL149890A0 (pt)
NZ (1) NZ519222A (pt)
PT (1) PT1237575E (pt)
WO (1) WO2001043773A1 (pt)

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US9849192B2 (en) 2009-11-18 2017-12-26 Rutgers, The State University Of New Jersey Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies
CA2818237C (en) 2009-11-18 2021-05-18 University Of Medicine And Dentistry Of New Jersey Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies
HUE036334T2 (hu) * 2010-08-27 2018-07-30 Anitox Corp Antimikrobális készítmény
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PL2785205T3 (pl) 2011-11-30 2021-06-28 Anitox Corporation Przeciwbakteryjna mieszanina aldehydów, kwasów organicznych i estrów kwasów organicznych
CA2879982C (en) 2012-07-25 2020-09-01 Sarcode Bioscience Inc. Lfa-1 inhibitor and polymorph thereof
WO2014046631A1 (en) 2012-09-19 2014-03-27 Tezcaner Aysen CONTROLED DRUG DELIVERY SYSTEMS FOR ANTI-TNF-α
CA2887037A1 (en) * 2012-10-02 2014-04-10 Rutgers, The State University Of New Jersey Specific delivery of toxins conjugated with antibodies to activated matriptase
KR20170138426A (ko) * 2015-03-13 2017-12-15 삼성바이오에피스 주식회사 항-tnf-알파 폴리펩티드 조성물 및 그 용도
RU2613056C1 (ru) * 2016-03-14 2017-03-15 Государственное бюджетное образовательное учреждение высшего профессионального образования "Южно-Уральский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО ЮУГМУ Минздрава России) Способ прогнозирования развития увеита у детей с ювенильным идиопатическим артритом
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EP1237575B1 (en) 2008-08-06
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US20050214291A1 (en) 2005-09-29
WO2001043773A1 (en) 2001-06-21
CA2394862C (en) 2011-10-11
DE60039783D1 (de) 2008-09-18
ES2311483T3 (es) 2009-02-16
EP1237575A1 (en) 2002-09-11
CN1409639A (zh) 2003-04-09
KR20020068372A (ko) 2002-08-27
US20080031875A1 (en) 2008-02-07
ATE403437T1 (de) 2008-08-15
CA2394862A1 (en) 2001-06-21
US20010031260A1 (en) 2001-10-18
NZ519222A (en) 2004-04-30
AU768324B2 (en) 2003-12-11
KR100567292B1 (ko) 2006-04-04
AU5439701A (en) 2001-06-25
IL149890A0 (en) 2002-11-10

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