DK1238094T3 - Fremgangsmåde til fremstilling af optisk aktive cyanhyhydriner under anvendelse af R-oxynitrilase - Google Patents

Fremgangsmåde til fremstilling af optisk aktive cyanhyhydriner under anvendelse af R-oxynitrilase

Info

Publication number
DK1238094T3
DK1238094T3 DK00989884T DK00989884T DK1238094T3 DK 1238094 T3 DK1238094 T3 DK 1238094T3 DK 00989884 T DK00989884 T DK 00989884T DK 00989884 T DK00989884 T DK 00989884T DK 1238094 T3 DK1238094 T3 DK 1238094T3
Authority
DK
Denmark
Prior art keywords
cyanhydrides
oxynitrilase
preparation
optically active
optically
Prior art date
Application number
DK00989884T
Other languages
Danish (da)
English (en)
Inventor
Peter Poechlauer
Irma Wirth
Herbert Mayrhofer
Rudolf Neuhofer
Original Assignee
Dsm Fine Chem Austria Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3527945&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1238094(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dsm Fine Chem Austria Gmbh filed Critical Dsm Fine Chem Austria Gmbh
Application granted granted Critical
Publication of DK1238094T3 publication Critical patent/DK1238094T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C12P13/004—Cyanohydrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK00989884T 1999-12-15 2000-11-25 Fremgangsmåde til fremstilling af optisk aktive cyanhyhydriner under anvendelse af R-oxynitrilase DK1238094T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0210899A AT408231B (de) 1999-12-15 1999-12-15 Verfahren zur herstellung von optisch aktiven cyanhydrinen unter verwendung von r-oxynitrilase
PCT/EP2000/011753 WO2001044487A1 (fr) 1999-12-15 2000-11-25 Procede de preparation de cyanhydrines actives du point de vue optique, par utilisation d'oxynitrilase r

Publications (1)

Publication Number Publication Date
DK1238094T3 true DK1238094T3 (da) 2004-04-13

Family

ID=3527945

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00989884T DK1238094T3 (da) 1999-12-15 2000-11-25 Fremgangsmåde til fremstilling af optisk aktive cyanhyhydriner under anvendelse af R-oxynitrilase

Country Status (12)

Country Link
US (1) US6717006B1 (fr)
EP (1) EP1238094B1 (fr)
JP (1) JP2003523736A (fr)
AT (1) AT408231B (fr)
AU (1) AU2668201A (fr)
CA (1) CA2393080A1 (fr)
CZ (1) CZ20021895A3 (fr)
DE (1) DE50005232D1 (fr)
DK (1) DK1238094T3 (fr)
ES (1) ES2211662T3 (fr)
IL (2) IL149891A0 (fr)
WO (1) WO2001044487A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT411065B (de) * 2001-12-27 2003-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von heterocyclischen (r)- und (s)-cyanhydrinen
AT411064B (de) * 2001-12-27 2003-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von enantiomerenangereicherten cyanhydrinen unter verwendung von acetalen oder ketalen als substrate
DE10219934A1 (de) * 2002-05-03 2003-11-20 Basf Ag Neue Proteine mit (R)-Hydroxynitril Lyase-Aktivität
EP2465929B1 (fr) 2006-12-14 2015-12-02 DSM IP Assets B.V. Variantes aléatoires de R-HNL et leur utilisation pour la préparation de cyanohydrines optiquement pures et stériquement entravées

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3701383A1 (de) * 1987-01-20 1988-07-28 Degussa Verfahren zur herstellung von optisch aktiven cyanhydrinen
DE3823864A1 (de) * 1988-01-29 1989-08-10 Kernforschungsanlage Juelich Enymatisches verfahren zur herstellung von optisch aktiven cyanhydrinen
DE4008412C1 (en) * 1990-03-16 1991-07-18 Forschungszentrum Juelich Gmbh, 5170 Juelich, De Optically active cyanohydrin prepn. useful insecticidal derivs. - comprising condensation of oxo-cpd. with hydrogen cyanide in presence of (R)- or (S) oxynitrilase
DE4102327C1 (en) * 1991-01-26 1992-06-04 Degussa Ag, 6000 Frankfurt, De (R)-keto:cyanohydrin prepn. - by reacting ketone with prussic acid in organic solvent in presence of (R)-oxy:nitrilase; used in prepn. of alpha-hydroxy-alpha-(m)ethyl carboxylic acid
EP0547655A1 (fr) * 1991-12-11 1993-06-23 Duphar International Research B.V Méthode de préparation de cyanohydrines optiquement actives
DE19506728A1 (de) 1995-02-27 1996-08-29 Degussa Verfahren zur Herstellung von (R)-Pantolacton
DE19703314A1 (de) 1996-02-09 1997-08-14 Degussa Verfahren zur Herstellung von (S)-Cyanhydrinen
AT406961B (de) 1997-12-29 2000-11-27 Dsm Fine Chem Austria Gmbh Enzymatisches verfahren zur herstellung von (s)-cyanhydrinen
DE19824491A1 (de) 1998-06-02 1999-12-09 Bayer Ag Verfahren zur stereoselektiven Herstellung von substituierten Cyclohexylcyanhydrinen

Also Published As

Publication number Publication date
EP1238094B1 (fr) 2004-02-04
AU2668201A (en) 2001-06-25
DE50005232D1 (de) 2004-03-11
ATA210899A (de) 2001-02-15
US6717006B1 (en) 2004-04-06
WO2001044487A1 (fr) 2001-06-21
CA2393080A1 (fr) 2001-06-21
AT408231B (de) 2001-09-25
EP1238094A1 (fr) 2002-09-11
IL149891A (en) 2008-04-13
ES2211662T3 (es) 2004-07-16
JP2003523736A (ja) 2003-08-12
CZ20021895A3 (cs) 2003-06-18
IL149891A0 (en) 2002-11-10

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