DK123877A - Fremgangsmade til fremstilling af 14-hydroxymorphinan-derivater - Google Patents

Fremgangsmade til fremstilling af 14-hydroxymorphinan-derivater

Info

Publication number: DK123877A
Authority: DK; Denmark
Prior art keywords: procedure; preparation; hydroxymorphinan derivatives; hydroxymorphinan; derivatives
Prior art date: 1976-03-23

Application number

DK123877A

Other languages

English (en)

Other versions

DK155322B (da

DK155322C (da

Inventor

I Monkovic

C Bachand

H Wong

G Lim

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-03-23

Filing date

1977-03-21

Publication date

1977-09-24

1976-03-23 Priority claimed from US05/669,795 external-priority patent/US4058531A/en

1977-02-17 Priority claimed from US05/769,808 external-priority patent/US4139534A/en

1977-03-21 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1977-09-24 Publication of DK123877A publication Critical patent/DK123877A/da

1989-03-28 Publication of DK155322B publication Critical patent/DK155322B/da

1989-09-11 Application granted granted Critical

1989-09-11 Publication of DK155322C publication Critical patent/DK155322C/da

Links

BLUMEJOOWLSPSE-OWCLPIDISA-N (1S,9R,10S)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2,4,6-trien-10-ol Chemical class C1CCC[C@@]2(O)[C@]3([H])NCC[C@@]21C1=CC=CC=C1C3 BLUMEJOOWLSPSE-OWCLPIDISA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pain & Pain Management (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)

DK123877A 1976-03-23 1977-03-21 Fremgangsmaade til fremstilling af 14-hydroxymorphinan-derivater og farmaceutisk acceptable syreadditionssalte deraf samt mellemprodukt til anvendelse ved fremgangsmaaden DK155322C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US05/669,795 US4058531A (en)	1976-03-23	1976-03-23	Process for the preparation of 14-hydroxymorphinan derivatives
US66979576		1976-03-23
US05/769,808 US4139534A (en)	1977-02-17	1977-02-17	Process for the preparation of 14-hydroxymorphinan derivatives
US76980877		1977-02-17

Publications (3)

Publication Number	Publication Date
DK123877A true DK123877A (da)	1977-09-24
DK155322B DK155322B (da)	1989-03-28
DK155322C DK155322C (da)	1989-09-11

Family

ID=27100195

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK123877A DK155322C (da)	1976-03-23	1977-03-21	Fremgangsmaade til fremstilling af 14-hydroxymorphinan-derivater og farmaceutisk acceptable syreadditionssalte deraf samt mellemprodukt til anvendelse ved fremgangsmaaden
DK597188A DK160987C (da)	1976-03-23	1988-10-27	9,10-dihydroxy-perhydroisoquinolinderivater til anvendelse som mellemprodukt ved fremstilling af 14-hydroxy-morphinanderivater

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK597188A DK160987C (da)	1976-03-23	1988-10-27	9,10-dihydroxy-perhydroisoquinolinderivater til anvendelse som mellemprodukt ved fremstilling af 14-hydroxy-morphinanderivater

Country Status (8)

Country	Link
JP (1)	JPS52136176A (da)
CA (1)	CA1086723A (da)
CH (1)	CH629783A5 (da)
DK (2)	DK155322C (da)
FI (1)	FI61486C (da)
LU (1)	LU77000A1 (da)
NL (2)	NL189846C (da)
SE (1)	SE431749B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0373510U (da) *	1989-11-15	1991-07-24
CA3019491A1 (en) *	2016-03-29	2017-10-05	Hikal Limited	An improved process for the preparation of butorphanol tartrate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3634429A (en) *	1969-09-30	1972-01-11	Hoffmann La Roche	Morphinan derivatives and preparation thereof
CA919668A (en) *	1970-06-20	1973-01-23	Murakami Masuo	Morphinan derivatives
BE788478A (fr) *	1971-09-08	1973-03-06	Bristol Myers Co	Procede de preparation de composes analgesiques
US3775414A (en) *	1972-05-10	1973-11-27	Bristol Myers Co	Process for the preparation of 14-hydroxymorphinan derivatives

1977
- 1977-03-17 JP JP2871277A patent/JPS52136176A/ja active Granted
- 1977-03-18 FI FI770865A patent/FI61486C/fi not_active IP Right Cessation
- 1977-03-18 NL NLAANVRAGE7703000,A patent/NL189846C/xx active Protection Beyond IP Right Term
- 1977-03-18 CA CA274,241A patent/CA1086723A/en not_active Expired
- 1977-03-21 DK DK123877A patent/DK155322C/da not_active IP Right Cessation
- 1977-03-21 SE SE7703236A patent/SE431749B/xx not_active IP Right Cessation
- 1977-03-22 CH CH358077A patent/CH629783A5/de not_active IP Right Cessation
- 1977-03-23 LU LU77000A patent/LU77000A1/xx unknown
1988
- 1988-10-27 DK DK597188A patent/DK160987C/da active
1996
- 1996-09-16 NL NL960022C patent/NL960022I1/nl unknown

Also Published As

Publication number	Publication date
FI61486B (fi)	1982-04-30
NL189846C (nl)	1993-08-16
DK597188A (da)	1988-10-27
FI770865A7 (da)	1977-09-24
SE431749B (sv)	1984-02-27
DK160987B (da)	1991-05-13
CH629783A5 (en)	1982-05-14
SE7703236L (sv)	1977-09-24
JPS52136176A (en)	1977-11-14
DK160987C (da)	1991-11-11
DK597188D0 (da)	1988-10-27
DK155322B (da)	1989-03-28
NL7703000A (nl)	1977-09-27
NL189846B (nl)	1993-03-16
FI61486C (fi)	1982-08-10
LU77000A1 (da)	1977-10-03
CA1086723A (en)	1980-09-30
JPS6139938B2 (da)	1986-09-06
NL960022I1 (nl)	1996-12-02
DK155322C (da)	1989-09-11

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Legal Events

Date	Code	Title	Description
1997-04-28	PUP	Patent expired