DK1248836T3 - Fremgangsmåde til fremstilling af vacciner ved anvendelse af hybridceller - Google Patents

Fremgangsmåde til fremstilling af vacciner ved anvendelse af hybridceller

Info

Publication number: DK1248836T3
Authority: DK; Denmark
Prior art keywords: cells; hybrid cells; hybrid; preparing vaccines; preparing
Prior art date: 2000-01-11

Application number

DK01908591T

Other languages

Danish (da)

English (en)

Inventor

Thomas Wagner

Yanzhang Wei

Original Assignee

Greenville Hospital System

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-11

Filing date

2001-01-09

Publication date

2005-08-15

2001-01-09 Application filed by Greenville Hospital System filed Critical Greenville Hospital System

2005-08-15 Application granted granted Critical

2005-08-15 Publication of DK1248836T3 publication Critical patent/DK1248836T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/428—Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/46—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/04—Amoebicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/57—Skin; melanoma

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Biotechnology (AREA)
Cell Biology (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Biochemistry (AREA)
Diabetes (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Developmental Biology & Embryology (AREA)
Transplantation (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK01908591T 2000-01-11 2001-01-09 Fremgangsmåde til fremstilling af vacciner ved anvendelse af hybridceller DK1248836T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17537600P	2000-01-11	2000-01-11
PCT/US2001/000571 WO2001051608A2 (fr)	2000-01-11	2001-01-09	Cellules hybrides

Publications (1)

Publication Number	Publication Date
DK1248836T3 true DK1248836T3 (da)	2005-08-15

Family

ID=22640013

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01908591T DK1248836T3 (da)	2000-01-11	2001-01-09	Fremgangsmåde til fremstilling af vacciner ved anvendelse af hybridceller

Country Status (11)

Country	Link
US (2)	US6849451B2 (fr)
EP (1)	EP1248836B1 (fr)
JP (1)	JP2003519486A (fr)
CN (1)	CN1427889B (fr)
AT (1)	ATE297981T1 (fr)
AU (1)	AU783931B2 (fr)
CA (2)	CA2396992C (fr)
DE (1)	DE60111490T2 (fr)
DK (1)	DK1248836T3 (fr)
ES (1)	ES2240417T3 (fr)
WO (1)	WO2001051608A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040058017A1 (en) *	1999-01-15	2004-03-25	Chow Sek Chuen	Pro-apoptotic agents
WO2004091551A2 (fr) *	2003-03-31	2004-10-28	Greenville Hospital System	Effets vasculaires antitumoraux des derives de l'albumine du serum humain
WO2005084387A2 (fr) *	2004-03-02	2005-09-15	Tsuneya Ohno	Procedes et compositions ayant trait a des vaccins de cellules hybrides de traitement et prevention du cancer
WO2007130050A1 (fr) *	2006-05-08	2007-11-15	Wagner Thomas E	Cellules hybrides pour le traitement de mélanomes précoces et tardifs non évolutifs
CA2704232C (fr) *	2007-11-08	2017-05-02	Dana-Farber Cancer Institute, Inc.	Stimulation de l'immunite anticancereuse a l'aide de fusions de cellules dendritiques/cellules tumorales et anti-cd3/cd28
US20130131640A1 (en) *	2010-05-10	2013-05-23	Orbis Health Solutions Llc	Method of creating and sorting fused cells
CN105821030A (zh) *	2015-01-04	2016-08-03	彭霞	表达α1，3半乳糖转移酶的癌细胞/树突状细胞融合肿瘤疫苗及其制备方法
CN105821029A (zh) *	2015-01-04	2016-08-03	彭霞	异源融合基因修饰的癌细胞/树突状细胞融合肿瘤疫苗及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4762701A (en)	1986-10-31	1988-08-09	Smithkline Beckman Corporation	In vivo cellular tracking
US4859584A (en)	1986-10-31	1989-08-22	Smithkline Beckman Corporation	Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes
US4783401A (en)	1986-10-31	1988-11-08	Smithkline Beckman Corporation	Viable cell labelling
JP2907473B2 (ja)	1988-09-27	1999-06-21	カイロンコーポレーション	細胞選別技術及びその利用
US20010012632A1 (en) *	1995-03-31	2001-08-09	Muriel Moser	Dendritic-like cell/tumor cell hybrids and hybridomas for inducing an anti-tumor response
AU5436796A (en) *	1995-03-31	1996-10-16	Catherine Bruyns	Dendritic-like cell/tumor cell hybrids and hybridomas for in ducing an anti-tumor response
DE69839215T2 (de)	1997-04-15	2009-03-19	Dana-Farber Cancer Institute, Inc., Boston	Dendritische zellhybride
US6197593B1 (en) *	1998-10-20	2001-03-06	Coulter International Corp.	Method for enumerating blood cells

2001
- 2001-01-09 CN CN018062296A patent/CN1427889B/zh not_active Expired - Lifetime
- 2001-01-09 US US09/756,293 patent/US6849451B2/en not_active Expired - Lifetime
- 2001-01-09 ES ES01908591T patent/ES2240417T3/es not_active Expired - Lifetime
- 2001-01-09 JP JP2001551182A patent/JP2003519486A/ja active Pending
- 2001-01-09 WO PCT/US2001/000571 patent/WO2001051608A2/fr not_active Ceased
- 2001-01-09 DK DK01908591T patent/DK1248836T3/da active
- 2001-01-09 AT AT01908591T patent/ATE297981T1/de active
- 2001-01-09 DE DE60111490T patent/DE60111490T2/de not_active Expired - Lifetime
- 2001-01-09 CA CA2396992A patent/CA2396992C/fr not_active Expired - Lifetime
- 2001-01-09 AU AU36443/01A patent/AU783931B2/en not_active Expired
- 2001-01-09 CA CA2823768A patent/CA2823768A1/fr not_active Abandoned
- 2001-01-09 EP EP01908591A patent/EP1248836B1/fr not_active Expired - Lifetime
2004
- 2004-12-22 US US11/017,733 patent/US20050158244A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1248836A2 (fr)	2002-10-16
WO2001051608A2 (fr)	2001-07-19
ATE297981T1 (de)	2005-07-15
CA2396992A1 (fr)	2001-07-19
EP1248836B1 (fr)	2005-06-15
WO2001051608A3 (fr)	2001-12-27
AU3644301A (en)	2001-07-24
CA2823768A1 (fr)	2001-07-19
CN1427889A (zh)	2003-07-02
US20050158244A1 (en)	2005-07-21
CA2396992C (fr)	2013-10-29
DE60111490D1 (de)	2005-07-21
AU783931B2 (en)	2005-12-22
US6849451B2 (en)	2005-02-01
DE60111490T2 (de)	2006-05-18
CN1427889B (zh)	2011-06-29
HK1057233A1 (en)	2004-03-19
ES2240417T3 (es)	2005-10-16
JP2003519486A (ja)	2003-06-24
US20010049142A1 (en)	2001-12-06

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ATE500323T1 (de)	2011-03-15	Subtilisin-variante
DK0918848T3 (da)	2007-04-10	Fremgangsmåder til at behandle kræftsygdomme og patogene infektioner ved anvendelse af antigenpræsenterende celler påfyldt med RNA
ES2109924T3 (es)	1998-02-01	Metodo rapido, versatil y simple de expresion de genes en celulas eucarioticas.
BR0212469A (pt)	2004-08-24	Método para multiplicação de vìrus em cultura de célula
DK1526172T3 (da)	2011-10-03	Fremgangsmåde til replikation af influenzavira i cellekultur og ved fremgangsmåden opnåelige influenzavira
AU2001236042A1 (en)	2001-11-22	Cell usable in serum-free culture and suspension culture and process for producing virus for vaccine by using the cell
BG101103A (bg)	1997-10-31	Теломераза при бозайници
DK1187852T3 (da)	2007-11-26	Ekspression og eksport af interferon-alpha-proteiner som Fc-fusionsproteiner
ITTV930017A0 (it)	1993-02-15	Struttura di contenitore, particolarmente per le colture cellulari
EE05212B1 (et)	2009-10-15	Polpeptiidi kasutamine farmatseutilise kompositsiooni valmistamiseks, mis on m?eldud kasvajaraku raviks, mis ekspresseerib APRIL-i
EA200601231A1 (ru)	2007-06-29	Дефинитивная энтодерма
IL210618A (en)	2015-06-30	Cell cultures containing isolated and multiplied human cells other than embryonic and germ cells, pharmaceutical preparations containing them, methods of preparation, and methods for identifying modulators and differentiation factors.
DK1629088T3 (da)	2012-05-07	Varianter af prostatastamcelleantigen (psca) og undersekvenser deraf
DK0506884T3 (da)	1996-11-04	Fremgangsmåde til afgivelse af molekyler til eukaryotiske celler
ES2249058T3 (es)	2006-03-16	Factores de preservacion de celulas progenitoras y metodos y productos relacionados.
CY1113064T1 (el)	2016-04-13	Νουκλεϊνικο οξυ και αντιστοιχη πρωτεϊνη με τιτλο 184ρ1ε2 χρησιμα στη θεραπεια και ανιχνευση καρκινου
BRPI0410562A (pt)	2006-06-20	molécula recombinante e veìculo para expressão, liberação e purificação de polipeptìdeos alvo
DE60111490D1 (de)	2005-07-21	Herstellung von vakzinen unter der verwendung von hybrid-zellen
CY1107431T1 (el)	2012-12-19	Σωματιδια για γoνιδιακη θεραπεια
MXPA02006094A (es)	2004-08-23	Metodos para producir embriones clonadod y adultos a partir de celulas cultivadas.
PL367306A1 (pl)	2005-02-21	Szczepionki na bazie autologicznych komórek T i sposoby ich otrzymywania
EP1541675A3 (fr)	2007-08-08	Cellules hybrides obtenues à partir de cellules présentatrices d'antigènes
WO2004078915A3 (fr)	2004-10-28	Culture cellulaire
DE3071618D1 (en)	1986-07-03	Thermophilic aspartase, processes for producing, culture used, and l-aspartic acid preparation process using the same
ES2132027A1 (es)	1999-08-01	Desarrollo de una piel artificial mediante cultivo de queratinocitos sobre una base de fibrina y fibroblastos humanos y metodo de preparacion de esta piel para trasplante.