DK1294732T3 - Ruthenium (II)-forbindelser til anvendelse i cancerterapi - Google Patents

Ruthenium (II)-forbindelser til anvendelse i cancerterapi

Info

Publication number: DK1294732T3
Authority: DK; Denmark
Prior art keywords: compounds; ruthenium; cancer therapy; sup; cancer
Prior art date: 2000-06-30

Application number

DK01945472T

Other languages

English (en)

Inventor

Robert Edward Morris

Duncan Jodrell

Haimei Chen

Peter John Sadler

Original Assignee

Univ Edinburgh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-30

Filing date

2001-06-26

Publication date

2004-12-06

2001-06-26 Application filed by Univ Edinburgh filed Critical Univ Edinburgh

2004-12-06 Application granted granted Critical

2004-12-06 Publication of DK1294732T3 publication Critical patent/DK1294732T3/da

Links

238000011275 oncology therapy Methods 0.000 title 1
YAYGSLOSTXKUBW-UHFFFAOYSA-N ruthenium(2+) Chemical class [Ru+2] YAYGSLOSTXKUBW-UHFFFAOYSA-N 0.000 title 1
206010028980 Neoplasm Diseases 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
125000002837 carbocyclic group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0046—Ruthenium compounds

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Inorganic Chemistry (AREA)
Epidemiology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK01945472T 2000-06-30 2001-06-26 Ruthenium (II)-forbindelser til anvendelse i cancerterapi DK1294732T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0016052.3A GB0016052D0 (en)	2000-06-30	2000-06-30	Ruthenium (II) compounds
PCT/GB2001/002824 WO2002002572A1 (en)	2000-06-30	2001-06-26	Ruthenium (ii) compounds for use in the therapy of cancer

Publications (1)

Publication Number	Publication Date
DK1294732T3 true DK1294732T3 (da)	2004-12-06

Family

ID=9894730

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01945472T DK1294732T3 (da)	2000-06-30	2001-06-26	Ruthenium (II)-forbindelser til anvendelse i cancerterapi

Country Status (14)

Country	Link
US (1)	US6936634B2 (da)
EP (1)	EP1294732B1 (da)
JP (1)	JP2004502696A (da)
AT (1)	ATE273985T1 (da)
AU (1)	AU2001267687A1 (da)
BR (1)	BR0112122A (da)
CA (1)	CA2414446A1 (da)
DE (1)	DE60105028T2 (da)
DK (1)	DK1294732T3 (da)
ES (1)	ES2227225T3 (da)
GB (1)	GB0016052D0 (da)
MX (1)	MXPA02012911A (da)
PT (1)	PT1294732E (da)
WO (1)	WO2002002572A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001030790A1 (en) *	1999-10-27	2001-05-03	The University Court, The University Of Edinburgh	Half-sandwich ruthenium (ii) compounds comprising nitrogen containing ligands for treatment of cancer
JP2005517648A (ja) *	2001-12-07	2005-06-16	インターミューンインコーポレイテッド	肝炎ウイルス感染症を治療するための組成物および方法
GB0215526D0 (en) *	2002-07-05	2002-08-14	Univ Edinburgh	Anticancer compounds
DK1618116T3 (da)	2003-04-30	2008-09-08	Univ Edinburgh	Ruthenium(II)-komplekser til behandling af tumorer
GB0418643D0 (en) *	2004-08-20	2004-09-22	Univ Edinburgh	Ruthenium (II) compounds
GB0604602D0 (en) *	2006-03-07	2006-04-19	Univ Edinburgh	Ruthenium (II) compounds
GB0610062D0 (en) *	2006-05-19	2006-06-28	Univ Edinburgh	Ruthenium (ll) compounds
CN101851256B (zh) *	2010-04-30	2013-01-09	广东药学院	一种以柔性碳链联接的钌(ⅱ)卟啉配合物及其制备方法和应用
CN101863925B (zh) *	2010-05-21	2012-08-29	广东药学院	一种芳基钌(ⅱ)配合物及其制备方法和应用
US9751081B2 (en)	2014-12-01	2017-09-05	Clemson University	Self-regenerating antioxidant catalysts and methods of using the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4980472A (en)	1983-06-23	1990-12-25	American Cyanamid Company	Method of making (3-amino-1H-pyrazol-4-yl) (aryl)methanones
EP0191096B1 (de)	1984-07-24	1989-09-13	ASTA Pharma AG	Tumorhemmend wirkende rutheniumverbindungen
EP0188585A1 (de)	1984-07-24	1986-07-30	Byk Gulden Lomberg Chemische Fabrik GmbH	Tumorhemmend wirkende rutheniumverbindungen
US5225556A (en)	1985-01-18	1993-07-06	The Trustees Of Columbia University In The City Of New York	Chemical probes for left-handed DNA and for A-DNA; chiral metal complexes as Z-specific antitumor agents and as double strand cleavers
US4980473A (en) *	1985-01-18	1990-12-25	The Trustees Of Columbia University In The City Of New York	Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
US4699978A (en)	1985-01-18	1987-10-13	The Trustees Of Columbia University In The City Of New York	Site-specific chiral ruthenium (II) and cobalt (III) antitumor agents
WO1996013510A1 (en)	1994-10-28	1996-05-09	Procept, Inc.	Ruthenium complexes and their use as immunosuppressive agents
JPH11209314A (ja)	1997-09-30	1999-08-03	Takasago Internatl Corp	シクロオクタジエン類の製造方法
JP3488103B2 (ja) *	1998-11-12	2004-01-19	高砂香料工業株式会社	４−メチル−５−ヘキセン−１−アールを含有する香料組成物
GB0028025D0 (en)	2000-11-17	2001-01-03	Univ York	Compounds

2000
- 2000-06-30 GB GBGB0016052.3A patent/GB0016052D0/en not_active Ceased
2001
- 2001-06-26 ES ES01945472T patent/ES2227225T3/es not_active Expired - Lifetime
- 2001-06-26 JP JP2002507824A patent/JP2004502696A/ja active Pending
- 2001-06-26 US US10/312,940 patent/US6936634B2/en not_active Expired - Fee Related
- 2001-06-26 WO PCT/GB2001/002824 patent/WO2002002572A1/en not_active Ceased
- 2001-06-26 DK DK01945472T patent/DK1294732T3/da active
- 2001-06-26 DE DE60105028T patent/DE60105028T2/de not_active Expired - Fee Related
- 2001-06-26 BR BR0112122-7A patent/BR0112122A/pt not_active Application Discontinuation
- 2001-06-26 CA CA002414446A patent/CA2414446A1/en not_active Abandoned
- 2001-06-26 MX MXPA02012911A patent/MXPA02012911A/es active IP Right Grant
- 2001-06-26 AT AT01945472T patent/ATE273985T1/de not_active IP Right Cessation
- 2001-06-26 PT PT01945472T patent/PT1294732E/pt unknown
- 2001-06-26 EP EP01945472A patent/EP1294732B1/en not_active Expired - Lifetime
- 2001-06-26 AU AU2001267687A patent/AU2001267687A1/en not_active Abandoned

Also Published As

Publication number	Publication date
MXPA02012911A (es)	2004-07-30
WO2002002572A1 (en)	2002-01-10
GB0016052D0 (en)	2000-08-23
DE60105028T2 (de)	2005-08-18
ES2227225T3 (es)	2005-04-01
AU2001267687A1 (en)	2002-01-14
JP2004502696A (ja)	2004-01-29
US20040029852A1 (en)	2004-02-12
US6936634B2 (en)	2005-08-30
BR0112122A (pt)	2003-05-13
DE60105028D1 (de)	2004-09-23
PT1294732E (pt)	2004-12-31
EP1294732B1 (en)	2004-08-18
ATE273985T1 (de)	2004-09-15
CA2414446A1 (en)	2002-01-10
EP1294732A1 (en)	2003-03-26

Publication	Publication Date	Title
ES2133807T3 (es)	1999-09-16	Compuestos de peptidilo y su uso terapeutico como inhibidores de metaloproteasas.
TR199901417T2 (xx)	1999-10-21	Analjezik etkisi olan yeni bile�imler.
ES2170252T3 (es)	2002-08-01	Tetrahidroimidazopiridoindoldionas como inhibidores de cgmp especifico pde.
MY138059A (en)	2009-04-30	Use of ikb-kinase inhibitors in pain therapy
SE0101387D0 (sv)	2001-04-20	Novel compounds
NO20023934D0 (no)	2002-08-19	Nye forbindelser
ATE334985T1 (de)	2006-08-15	Verbindungen, verfahren und pharmazeutische zubereitungen zur behandlung von zellschäden wie zum beispiel schäden an nerven- oder kerzgefässgewebe
PE20020521A1 (es)	2002-07-15	Compuestos heterociclicos sustituidos para tratar la resistencia a multiples drogas
PA8432901A1 (es)	2000-05-24	Compuestos de piridilpirrol
BR9805544C1 (pt)	2000-06-06	Uso de um composto.
DE60045508D1 (de)	2011-02-24	Dalda-analoge und ihre verwendung
NZ513096A (en)	2003-01-31	Compositions for treating inflammatory response
ES2101858T3 (es)	1997-07-16	Derivados de geneserina como inhibidores de colinesterasa.
DK1294732T3 (da)	2004-12-06	Ruthenium (II)-forbindelser til anvendelse i cancerterapi
BR0205812A (pt)	2005-05-03	Benzimidazois úteis no tratamento da disfunção sexual
ES2135769T3 (es)	1999-11-01	Derivados de isotiourea como inhibidores de no-sintasa.
SE9904674D0 (sv)	1999-12-20	Novel compounds
SE0003476D0 (sv)	2000-09-28	Compounds
AR020563A1 (es)	2002-05-15	Compuestos (poli)tia-alquinoicos y sus derivados, composiciones que los incluyen y su utilizacion
BR0309996A (pt)	2005-02-22	Composto, composição farmacêutica, método de tratar ou melhorar doenças ou condições proliferativas, uso de um composto, e, método de tratar ou melhorar doenças inflamatórias
MX9700624A (es)	1997-12-31	Azolidinonas de imidazopiridina.
ES2149193T3 (es)	2000-11-01	Compuestos heterociclicos sustituidos con alquilo.
UY26498A1 (es)	2001-06-29	Pirroles sustituidos
SE0403118D0 (sv)	2004-12-21	New compounds 2
SE0004827D0 (sv)	2000-12-22	Therapeutic compounds