DK1311264T3 - Substituerede og usubstituerede benzooxathiaxoler og deres afledte forbindelser - Google Patents

Substituerede og usubstituerede benzooxathiaxoler og deres afledte forbindelser

Info

Publication number
DK1311264T3
DK1311264T3 DK01969532T DK01969532T DK1311264T3 DK 1311264 T3 DK1311264 T3 DK 1311264T3 DK 01969532 T DK01969532 T DK 01969532T DK 01969532 T DK01969532 T DK 01969532T DK 1311264 T3 DK1311264 T3 DK 1311264T3
Authority
DK
Denmark
Prior art keywords
unsubstituted
substituted
benzooxathiaxols
derivative compounds
dioxides
Prior art date
Application number
DK01969532T
Other languages
English (en)
Inventor
Stefan Petry
Karl-Heinz Baringhaus
Swen Hoelder
Guenter Mueller
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1311264T3 publication Critical patent/DK1311264T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/14Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D291/00Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
    • C07D291/08Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DK01969532T 2000-08-09 2001-07-27 Substituerede og usubstituerede benzooxathiaxoler og deres afledte forbindelser DK1311264T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10038709A DE10038709A1 (de) 2000-08-09 2000-08-09 Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen
PCT/EP2001/008704 WO2002011722A1 (de) 2000-08-09 2001-07-27 Substituierte und unsubstituierte benzooxathiazole sowie daraus abgeleitete verbindungen

Publications (1)

Publication Number Publication Date
DK1311264T3 true DK1311264T3 (da) 2007-09-10

Family

ID=7651742

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01969532T DK1311264T3 (da) 2000-08-09 2001-07-27 Substituerede og usubstituerede benzooxathiaxoler og deres afledte forbindelser

Country Status (13)

Country Link
US (3) US6566390B2 (da)
EP (1) EP1311264B1 (da)
JP (1) JP2004505916A (da)
AT (1) ATE365552T1 (da)
AU (1) AU2001289763A1 (da)
CA (1) CA2418084C (da)
CY (1) CY1107736T1 (da)
DE (2) DE10038709A1 (da)
DK (1) DK1311264T3 (da)
ES (1) ES2284689T3 (da)
MX (1) MXPA03000678A (da)
PT (1) PT1311264E (da)
WO (1) WO2002011722A1 (da)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10038709A1 (de) * 2000-08-09 2002-02-28 Aventis Pharma Gmbh Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen
GB0227813D0 (en) * 2002-11-29 2003-01-08 Astrazeneca Ab Chemical compounds
DE10308355A1 (de) 2003-02-27 2004-12-23 Aventis Pharma Deutschland Gmbh Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
DE10334309A1 (de) * 2003-07-28 2005-03-03 Aventis Pharma Deutschland Gmbh Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
US7094794B2 (en) 2003-07-28 2006-08-22 Sanofi-Aventis Deutschland Gmbh Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use
US7141596B2 (en) 2003-10-08 2006-11-28 Incyte Corporation Inhibitors of proteins that bind phosphorylated molecules
DE102004026532A1 (de) 2004-05-29 2006-01-05 Sanofi-Aventis Deutschland Gmbh Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
WO2007014137A2 (en) * 2005-07-21 2007-02-01 Rensselaer Polytechnic Institute 8-carboxamido-substituted-2 , 6-methano-3-benzazocines and 3 - carboxamido- substituted morphanes as opioid receptor binding agents
WO2008107699A1 (en) * 2007-03-08 2008-09-12 Cambridge Enterprise Limited Diagnosing psychotic disorders
DE102008022221A1 (de) * 2008-05-06 2009-11-12 Universität des Saarlandes Inhibitoren der humanen Aldosteronsynthase CYP11B2
EP2683704B1 (de) * 2011-03-08 2014-12-17 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8895547B2 (en) 2011-03-08 2014-11-25 Sanofi Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2766349B1 (de) * 2011-03-08 2016-06-01 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2013078413A1 (en) * 2011-11-22 2013-05-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Modulators of lipid storage

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US3539584A (en) * 1967-11-14 1970-11-10 Colgate Palmolive Co 5-substituted-2,1-benzisothiazolines
DE3311636A1 (de) * 1983-03-30 1984-10-04 Bayer Ag, 5090 Leverkusen Neue fuenfgliedrige stickstoffhaltige heterocyclen, verfahren zu ihrer herstellung sowie ihre verwendung als schaedlingsbekaempfungsmittel
JPH04128276A (ja) 1990-09-19 1992-04-28 Pfizer Pharmaceut Co Ltd アミノベンゾサルタム誘導体およびその用途
US5504095A (en) * 1990-09-19 1996-04-02 Pfizer Inc. Aminobenzosultam derivatives as lipoxygenase inhibitors
US5130432A (en) * 1990-12-21 1992-07-14 Syntex (U.S.A.) Inc. Process for preparing cyclic amines and intermediate products thereof
EP0549348A1 (en) * 1991-12-24 1993-06-30 PHARMACIA S.p.A. Arylidene-heterocyclic derivatives, process for their preparation and their use as tyrisine kinase inhibitors
ES2173182T3 (es) * 1994-04-11 2002-10-16 Chugai Pharmaceutical Co Ltd Derivado de 4,6-dl-butil-2,3-dihidrobenzotiofenos como antioxidantes de ldl.
JPH07325942A (ja) 1994-05-31 1995-12-12 Mitsubishi Heavy Ind Ltd カード類処理装置
WO1995033746A1 (en) * 1994-06-08 1995-12-14 E.I. Du Pont De Nemours And Company Cyclic sulfonamide herbicides
AU6613296A (en) 1995-07-20 1997-02-18 Basf Aktiengesellschaft Chroman derivatives, their preparation and their use as stabilizers of organic material against light, oxygen and heat
US5874382A (en) * 1996-11-13 1999-02-23 E. I. Du Pont De Nemours And Company Cyclic sulfonamide herbicides
US5929250A (en) * 1997-01-23 1999-07-27 Smithkline Beecham Corporation IL-8 receptor antagonists
US6300325B1 (en) * 1997-01-23 2001-10-09 Smithkline Beecham Corporation IL-8 receptor antagonists
AR008331A1 (es) * 1997-01-23 1999-12-29 Smithkline Beecham Corp Compuestos antagonistas de un receptor de il-8, uso de los mismos para la fabricacion de medicamentos, procedimiento para su obtencion, composicionesfarmaceuticas que los contienen
DE19738005A1 (de) * 1997-08-30 1999-03-04 Bayer Ag Verwendung von substituierten 1,1-Bisphosphonaten
AR015426A1 (es) * 1997-09-05 2001-05-02 Smithkline Beecham Corp Compuestos de benzotiazol antagonistas del receptor de il-8, composicion farmaceutica que los contiene, su uso para la manufactura de un medicamento,procedimiento para su preparacion, compuestos intermediarios y procedimiento para su preparacion
AR015425A1 (es) * 1997-09-05 2001-05-02 Smithkline Beecham Corp Compuestos de benzotiazol, composicion farmaceutica que los contiene, su uso en la manufactura de un medicamento, procedimiento para su preparacion,compuestos intermediarios y procedimiento para su preparacion
CA2318195A1 (en) * 1998-01-16 1999-07-22 Deborah Lynne Bryan Il-8 receptor antagonists
WO1999046237A1 (en) * 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases
US6001867A (en) * 1998-05-12 1999-12-14 American Home Products Corporation 1-aryl-dibenzothiophenes
CN1314893A (zh) * 1998-07-23 2001-09-26 史密丝克莱恩比彻姆公司 Il-8受体拮抗剂
WO2000006557A1 (en) * 1998-07-27 2000-02-10 Smithkline Beecham Corporation Novel process for making il-8 receptor antagonists
JP2002527446A (ja) * 1998-10-14 2002-08-27 バーゼル、ポリプロピレン、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツング 固定した架橋を有するメタロセン
US6319912B1 (en) * 1999-05-04 2001-11-20 American Home Products Corporation Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides
US6339098B1 (en) * 1999-05-04 2002-01-15 American Home Products Corporation 2,1-benzisothiazoline 2,2-dioxides
DE10038709A1 (de) * 2000-08-09 2002-02-28 Aventis Pharma Gmbh Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen

Also Published As

Publication number Publication date
US7211592B2 (en) 2007-05-01
JP2004505916A (ja) 2004-02-26
WO2002011722A1 (de) 2002-02-14
ES2284689T3 (es) 2007-11-16
DE10038709A1 (de) 2002-02-28
US20050043373A1 (en) 2005-02-24
AU2001289763A1 (en) 2002-02-18
CA2418084C (en) 2010-03-30
CA2418084A1 (en) 2003-02-04
CY1107736T1 (el) 2013-04-18
US20020055523A1 (en) 2002-05-09
ATE365552T1 (de) 2007-07-15
US6566390B2 (en) 2003-05-20
PT1311264E (pt) 2007-07-31
EP1311264B1 (de) 2007-06-27
EP1311264A1 (de) 2003-05-21
DE50112671D1 (de) 2007-08-09
MXPA03000678A (es) 2003-06-06
US20030191161A1 (en) 2003-10-09

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