DK1313712T3 - Fremgangsmåde og mellemforbindelser til fremstilling af retrovirale proteaseinhibitorer - Google Patents

Fremgangsmåde og mellemforbindelser til fremstilling af retrovirale proteaseinhibitorer

Info

Publication number
DK1313712T3
DK1313712T3 DK01966367T DK01966367T DK1313712T3 DK 1313712 T3 DK1313712 T3 DK 1313712T3 DK 01966367 T DK01966367 T DK 01966367T DK 01966367 T DK01966367 T DK 01966367T DK 1313712 T3 DK1313712 T3 DK 1313712T3
Authority
DK
Denmark
Prior art keywords
intermediates
preparation
protease inhibitors
retroviral protease
amino
Prior art date
Application number
DK01966367T
Other languages
English (en)
Inventor
Sanjay R Chemburkar
Harry O Spiwek
Ketan M Patel
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24614772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1313712(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK1313712T3 publication Critical patent/DK1313712T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/10Oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
DK01966367T 2000-08-31 2001-08-29 Fremgangsmåde og mellemforbindelser til fremstilling af retrovirale proteaseinhibitorer DK1313712T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65191900A 2000-08-31 2000-08-31
PCT/US2001/026898 WO2002018349A2 (en) 2000-08-31 2001-08-29 Process and intermediates for preparing retroviral protease inhibitors

Publications (1)

Publication Number Publication Date
DK1313712T3 true DK1313712T3 (da) 2007-09-10

Family

ID=24614772

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01966367T DK1313712T3 (da) 2000-08-31 2001-08-29 Fremgangsmåde og mellemforbindelser til fremstilling af retrovirale proteaseinhibitorer

Country Status (16)

Country Link
EP (1) EP1313712B1 (da)
JP (1) JP5021141B2 (da)
KR (1) KR100806533B1 (da)
CN (1) CN1264823C (da)
AT (1) ATE361913T1 (da)
AU (1) AU2001286889A1 (da)
BR (1) BR0108146A (da)
CA (2) CA2731273C (da)
CY (1) CY1106738T1 (da)
DE (1) DE60128367T2 (da)
DK (1) DK1313712T3 (da)
ES (1) ES2284684T3 (da)
IL (1) IL153436A0 (da)
MX (1) MXPA03001751A (da)
PT (1) PT1313712E (da)
WO (1) WO2002018349A2 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2378669T3 (es) * 2003-12-11 2012-04-16 Abbott Laboratories Compuestos inhibidores de proteasa de VIH
CN100358521C (zh) * 2004-12-28 2008-01-02 哈尔滨欧替药业股份有限公司 一种双唑泰栓剂及其制备工艺
CN103910634B (zh) * 2012-12-29 2018-04-27 广东东阳光药业有限公司 西格列汀中间体的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914332A (en) * 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds

Also Published As

Publication number Publication date
CA2731273A1 (en) 2002-03-07
CA2731273C (en) 2013-10-15
PT1313712E (pt) 2007-07-25
CA2416955C (en) 2011-04-26
EP1313712B1 (en) 2007-05-09
KR20030061787A (ko) 2003-07-22
WO2002018349A2 (en) 2002-03-07
JP5021141B2 (ja) 2012-09-05
ES2284684T3 (es) 2007-11-16
CY1106738T1 (el) 2012-05-23
IL153436A0 (en) 2003-07-06
AU2001286889A1 (en) 2002-03-13
CA2416955A1 (en) 2002-03-07
WO2002018349A3 (en) 2002-05-10
HK1057040A1 (en) 2004-03-12
JP2004507528A (ja) 2004-03-11
MXPA03001751A (es) 2003-09-10
CN1449388A (zh) 2003-10-15
CN1264823C (zh) 2006-07-19
EP1313712A2 (en) 2003-05-28
DE60128367T2 (de) 2008-01-10
KR100806533B1 (ko) 2008-02-25
ATE361913T1 (de) 2007-06-15
DE60128367D1 (de) 2007-06-21
BR0108146A (pt) 2004-01-06

Similar Documents

Publication Publication Date Title
MXPA03005219A (es) Peptidos diarilicos como inhibidores de ns3-serina proteasa en hepatitis de virus c.
BR0215405A (pt) Composições e processos de uso de collajolie
NO20035488D0 (no) HV-protease-inhibitorer, blandinger inneholdende disse, deres farmas degree ytiskeanvendelser og materialer for deres syntese
DK1171417T3 (da) Fremgangsmåde til fremstilling af 3-aryloxy-3-arylpropylaminer og mellemprodukter deraf
TR200103390T2 (tr) Proteaz inhibitörleri olan yeni bileşikler ve terkipler.
DK1362052T3 (da) Inhibitorer af cruzipain og andre cysteinproteaser
SE0002102D0 (sv) Chemical compound
DK1097173T3 (da) Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler
TR200003028T2 (tr) Yeni ikame edilmiş amidler, bunların üretimi ve kullanımı.
DK1456212T3 (da) 6-aminomorphinanderivater, fremgangsmåder til fremstilling heraf og disses anvendelse
DE60215623D1 (de) Breitspektrum 2-(substituierte-amino)-benzothiazol-sulfonamide hiv protease inhibitoren
DK1017684T3 (da) Kontrastmiddel til afbildning af infarkter og nekroser
MXPA04004805A (es) Peptido novedoso que tiene un efecto inhibidor de la enzima convertidora de angiotensina.
BR0312889A (pt) Polipeptìdeo t20 peguilado
DK0804410T3 (da) Fremgangsmåde til fremstilling af retrovirale proteaseinhibitor-mellemprodukter
ATE433458T1 (de) Modulatoren von ship-1
DK1299429T3 (da) Scavengerharpiks og fremgangsmåder til anvendelse deraf
DK1313712T3 (da) Fremgangsmåde og mellemforbindelser til fremstilling af retrovirale proteaseinhibitorer
IS2273B (is) Aðferð fyrir nýsmíðina á HIV próteasa lötum
EA200400392A1 (ru) Связывающий каспазу-8 белок, его получение и применение
BR0316544A (pt) Compostos calcilìticos
DK1318142T3 (da) t-butoxycarbonylaminoethylamin til syntese af PNA-monomerenheder, aminosyrederivater, mellemprodukter deraf og fremgangsmåder til fremstilling af disse
NO20024679D0 (no) Krystallinsk farmasöytikum
TR200100906T2 (tr) Trombin inhibitörleri olarak benzamid türevleri
WO2003097593A3 (en) Protease inhibitors