DK131858C - Analogifremgangsmade til fremstilling af 4-amino-6-arylpyrimidin-forbindelser eller syreadditionssalte deraf - Google Patents

Analogifremgangsmade til fremstilling af 4-amino-6-arylpyrimidin-forbindelser eller syreadditionssalte deraf

Info

Publication number: DK131858C
Authority: DK; Denmark
Prior art keywords: amino; preparation; additional salts; acid additional; arylpyrimidine
Prior art date: 1970-10-05

Application number

DK480171A

Other languages

English (en)

Other versions

DK131858B (da

Inventor

G G D Angelis

H J E Hess

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-10-05

Filing date

1971-10-01

Publication date

1976-02-16

1971-10-01 Application filed by Pfizer filed Critical Pfizer

1973-03-16 Priority to DK142973A priority Critical patent/DK130971B/da

1975-09-15 Publication of DK131858B publication Critical patent/DK131858B/da

1976-02-16 Application granted granted Critical

1976-02-16 Publication of DK131858C publication Critical patent/DK131858C/da

Links

239000002253 acid Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK480171A 1970-10-05 1971-10-01 Analogifremgangsmade til fremstilling af 4-amino-6-arylpyrimidin-forbindelser eller syreadditionssalte deraf DK131858C (da)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK142973A DK130971B (da)	1970-10-05	1973-03-16	Analogifremgangsmåde til fremstilling af 4-hydroxy-5-ethyl-6-phenylpyrimidin.

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US7821670A	1970-10-05	1970-10-05

Publications (2)

Publication Number	Publication Date
DK131858B DK131858B (da)	1975-09-15
DK131858C true DK131858C (da)	1976-02-16

Family

ID=22142671

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK480171A DK131858C (da)	1970-10-05	1971-10-01	Analogifremgangsmade til fremstilling af 4-amino-6-arylpyrimidin-forbindelser eller syreadditionssalte deraf

Country Status (16)

Country	Link
US (1)	US3707560A (da)
JP (2)	JPS5648511B1 (da)
AT (4)	AT315856B (da)
AU (1)	AU465734B2 (da)
BE (1)	BE773484A (da)
CA (1)	CA988519A (da)
CH (4)	CH554875A (da)
DE (2)	DE2149249C3 (da)
DK (1)	DK131858C (da)
ES (4)	ES395676A1 (da)
FI (1)	FI55502C (da)
FR (1)	FR2110227B1 (da)
GB (2)	GB1373535A (da)
NL (1)	NL168511C (da)
SE (2)	SE385885B (da)
ZA (1)	ZA716615B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3908012A (en) *	1970-10-05	1975-09-23	Pfizer	Arylpyrimidines-inhibitors of platelet aggregation and bronchodilators
US3895112A (en) *	1970-10-05	1975-07-15	Pfizer	Arylpyrimidines in the relaxation of smooth muscle
US3859288A (en) *	1970-10-05	1975-01-07	Pfizer	Arylpyrimidines - inhibitors of platelet aggregation and bronchodilators
US3835132A (en) *	1972-02-01	1974-09-10	Shell Oil Co	Morpholino-piperazinyl pyrimidines
US3950525A (en) *	1973-06-19	1976-04-13	Pfizer Inc.	Relaxation of smooth muscle in a mammal
DE2343419A1 (de) *	1973-08-29	1975-03-13	Gruenenthal Chemie	Verfahren zur herstellung von pyrimidinderivaten
US4725600A (en) *	1984-07-13	1988-02-16	Fujisawa Pharmaceutical Co., Ltd.	Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent
US4935516A (en) *	1988-01-29	1990-06-19	Ube Industries, Ltd.	Process for preparing 4-hydroxypyrimidine
JPH0625157B2 (ja) *	1988-01-29	1994-04-06	宇部興産株式会社	４―ヒドロキシピリミジン類の製造方法
DE3825647A1 (de) *	1988-07-28	1990-02-01	Geyer Gmbh & Co Christian	Vorrichtung zur befestigung eines elektrischen schaltgeraetes
DE3905364A1 (de) *	1989-02-22	1990-08-23	Hoechst Ag	Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool
ATE250053T1 (de) *	1999-07-15	2003-10-15	Pharmacopeia Inc	Bradikinin b1 rezeptor antagonisten
AU2003214110A1 (en) *	2002-03-15	2003-09-29	Ciba Specialty Chemicals Holding Inc.	4-aminopyrimidines and their use for the antimicrobial treatment of surfaces
JP2005531574A (ja) *	2002-05-22	2005-10-20	アムジエン・インコーポレーテツド	痛みの治療にバニロイド受容体リガンドとして使用するためのアミノ−ピリジン、−ピリジンおよびピリダジン誘導体
JP2006521345A (ja) *	2003-03-28	2006-09-21	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	ニコチン性アセチルコリン受容体の正のアロステリック調節剤
US20060235036A1 (en) *	2005-04-15	2006-10-19	Doherty Elizabeth M	Vanilloid receptor ligands and their use in treatments
JP2009164373A (ja) *	2008-01-08	2009-07-23	Toshiba Corp	半導体装置
NZ601547A (en) *	2010-01-25	2014-04-30	Chdi Foundation Inc	Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
WO2013033068A1 (en)	2011-08-30	2013-03-07	Stephen Martin Courtney	Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
SG2014012926A (en)	2011-08-30	2014-06-27	Chdi Foundation Inc	Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
MX372995B (es)	2014-07-17	2020-04-13	Chdi Foundation Inc	Metodos y composiciones para el tratamiento de trastornos relacionados con vih.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3047462A (en) *	1959-03-06	1962-07-31	Lab Jacques Logeais Soc D Expl	Quinazolone anti-inflammatory composition

1970
- 1970-10-05 US US78216A patent/US3707560A/en not_active Expired - Lifetime
1971
- 1971-09-30 FI FI2734/71A patent/FI55502C/fi active
- 1971-10-01 DK DK480171A patent/DK131858C/da not_active IP Right Cessation
- 1971-10-02 DE DE2149249A patent/DE2149249C3/de not_active Expired
- 1971-10-02 DE DE2165962A patent/DE2165962C2/de not_active Expired
- 1971-10-04 SE SE7112534-8A patent/SE385885B/xx unknown
- 1971-10-04 ZA ZA716615A patent/ZA716615B/xx unknown
- 1971-10-04 ES ES395676A patent/ES395676A1/es not_active Expired
- 1971-10-04 GB GB4615871A patent/GB1373535A/en not_active Expired
- 1971-10-04 SE SE7410488A patent/SE390304B/xx unknown
- 1971-10-04 GB GB3831673A patent/GB1373536A/en not_active Expired
- 1971-10-04 CA CA124,312A patent/CA988519A/en not_active Expired
- 1971-10-05 AT AT00148/73A patent/AT315856B/de not_active IP Right Cessation
- 1971-10-05 AT AT858071A patent/AT314540B/de not_active IP Right Cessation
- 1971-10-05 AT AT00149/73A patent/AT316563B/de not_active IP Right Cessation
- 1971-10-05 NL NLAANVRAGE7113670,A patent/NL168511C/xx not_active IP Right Cessation
- 1971-10-05 CH CH1521472A patent/CH554875A/fr not_active IP Right Cessation
- 1971-10-05 FR FR7135815A patent/FR2110227B1/fr not_active Expired
- 1971-10-05 AT AT605473A patent/AT317229B/de not_active IP Right Cessation
- 1971-10-05 CH CH1532172A patent/CH554346A/fr not_active IP Right Cessation
- 1971-10-05 JP JP7823771A patent/JPS5648511B1/ja active Pending
- 1971-10-05 BE BE773484A patent/BE773484A/xx not_active IP Right Cessation
- 1971-10-05 CH CH1452971A patent/CH554876A/fr not_active IP Right Cessation
- 1971-10-05 CH CH772973A patent/CH542218A/fr not_active IP Right Cessation
- 1971-10-06 AU AU34259/71A patent/AU465734B2/en not_active Expired
1973
- 1973-11-02 ES ES420211A patent/ES420211A1/es not_active Expired
- 1973-11-02 ES ES420209A patent/ES420209A1/es not_active Expired
- 1973-11-02 ES ES420210A patent/ES420210A1/es not_active Expired
1980
- 1980-08-11 JP JP11016380A patent/JPS5636468A/ja active Granted

Also Published As

Publication number	Publication date
SE7410488L (da)	1974-08-16
DE2165962C2 (de)	1982-05-13
NL7113670A (da)	1972-04-07
CH554876A (fr)	1974-10-15
GB1373535A (en)	1974-11-13
ES395676A1 (es)	1974-10-16
JPS578107B2 (da)	1982-02-15
ES420211A1 (es)	1976-03-16
SE390304B (sv)	1976-12-13
ZA716615B (en)	1972-06-28
SE385885B (sv)	1976-07-26
DE2149249C3 (de)	1975-07-03
FI55502B (fi)	1979-04-30
ES420210A1 (es)	1976-06-01
JPS5636468A (en)	1981-04-09
US3707560A (en)	1972-12-26
CH554875A (fr)	1974-10-15
CH554346A (fr)	1974-09-30
JPS5648511B1 (da)	1981-11-16
AT315856B (de)	1974-05-15
GB1373536A (en)	1974-11-13
ES420209A1 (es)	1976-06-01
AU3425971A (en)	1973-04-12
AT317229B (de)	1974-08-26
CA988519A (en)	1976-05-04
AU465734B2 (en)	1975-10-09
FR2110227B1 (da)	1975-02-07
FI55502C (fi)	1979-08-10
AT316563B (de)	1974-06-15
NL168511C (nl)	1982-04-16
CH542218A (fr)	1973-11-15
DK131858B (da)	1975-09-15
DE2149249B2 (de)	1974-11-07
AT314540B (de)	1974-04-10
DE2149249A1 (de)	1972-04-13
BE773484A (fr)	1972-04-05
FR2110227A1 (da)	1972-06-02
DE2165962A1 (de)	1972-08-31
NL168511B (nl)	1981-11-16

Legal Events

Date	Code	Title	Description
1985-06-03	PBP	Patent lapsed

Publication	Publication Date	Title
DK129446B (da)	1974-10-14	Analogifremgangsmåde til fremstilling af fenoxyhydroxypropylaminer eller syreadditionssalte heraf.
DK135585B (da)	1977-05-23	Analogifremgangsmade til fremstilling af cycloheptenderivater eller syreadditionssalte deraf
DK132759C (da)	1976-07-05	Analogifremgangsmade til fremstilling af alfa-aminopenicillinestere eller syreadditionssalte deraf eller de tilsvarende optiske antipoder
DK131858B (da)	1975-09-15	Analogifremgangsmåde til fremstilling af 4-amino-6-arylpyrimidin-forbindelser eller syreadditionssalte deraf.
DK131935C (da)	1976-02-23	Analogifremgangsmade til fremstilling af aminoalkynyllaktamforbindelser eller syreadditionssalte deraf
DK131778C (da)	1976-02-02	Fremgangsmade til fremstilling af substituerede 3-hydroksymetylisokinolinderivater eller syreadditionssalte heraf
DK137606C (da)	1978-09-18	Analogifremgangsmaade til fremstilling af substituerede 2-phenylamino-imidazoliner-(2) eller syreadditionssalte deraf
DK131857C (da)	1976-02-16	Analogifremgangsmade til fremstilling af 4-hydroxymethyl-1-phthalazonderivater eller syreadditionssalte deraf
DK139517C (da)	1979-08-20	Analogifremgangsmaade til fremstilling af substituerede thiazol-2-carboxamider eller syreadditionssalte deraf
DK142984C (da)	1981-09-28	Analogifremgangsmaade til fremstilling af benzobicycloalkanaminer eller farmaceutisk acceptable syreadditionssalte deraf
DK133301C (da)	1976-09-27	Analogifremgangsmade til fremstilling af penicillanforbindelser eller salte deraf
DK132627C (da)	1976-08-02	Analogifremgangsmade til fremstilling af kromanderivater eller syreadditionssalte deraf
DK133278C (da)	1976-09-20	Fremgangsmade til fremstilling af 1-phenyl-4-amino-cyclohex-2-en-1-carboxylsyreestere eller syreadditionssalte eller kvaternere ammoniumforbindelser deraf
DK134438C (da)	1977-05-31	Analogifremgangsmade til fremstilling af pencilliner eller salte deraf
DK133149B (da)	1976-03-29	Analogifremgangsmade til fremstilling af et guanidinphenylurinstofderivat eller syreadditionssalte deraf
DK131727C (da)	1976-03-29	Analogifremgangsmade til fremstilling af oxazinobenzoxaziner eller syreadditionssalte deraf
DK135941C (da)	1978-01-30	Analogifremgangsmaade til fremstilling af 1-cyclopropyl-1-phenyl-3-amino-1-propanoler eller syreaddittionssalte deraf
DK129164B (da)	1974-09-02	Analogifremgangsmåde til fremstilling af 3-alkyl-5-aryloxymethylisoxazoler eller syreadditionssalte deraf.
DK132755C (da)	1976-07-12	Analogifremgangsmade til fremstilling af benzomorphanderivater eller syreadditionssalte deraf
DK132076C (da)	1976-03-08	Fremgangsmade til fremstilling af benzomorphanderivater ellerdisses syreadditionssalte
DK129839B (da)	1974-11-25	Analogifremgangsmåde til fremstilling af N-vinylquinoloner eller syreadditionssalte deraf.
DK134752C (da)	1977-07-04	Analogifremgangsmade til fremstilling af(+)-3r-n-monomethyl-amino-4c-phenyl-4t-ethoxycarbonyl-cyclohexen-(1)eller syreadditionssalte deraf
DK132077C (da)	1976-03-15	Analogifremgangsmade til fremstilling af substituerede n-aminoalkyl-arylaminoimidazolin-(2)-forbindelser eller syreadditionssalte deraf
DK130965B (da)	1975-05-12	Fremgangsmåde til fremstilling af gamma-piperidinobutyrophenonforbindelser eller syreadditionssalte deraf.
DK240477A (da)	1977-06-01	Analogifremgangsmade til fremstilling af 3-phenoxyphenylalkyltetrazol-forbindelser eller syreadditionssalte deraf