DK1321144T3 - Øjendråber - Google Patents
ØjendråberInfo
- Publication number
- DK1321144T3 DK1321144T3 DK01965597.6T DK01965597T DK1321144T3 DK 1321144 T3 DK1321144 T3 DK 1321144T3 DK 01965597 T DK01965597 T DK 01965597T DK 1321144 T3 DK1321144 T3 DK 1321144T3
- Authority
- DK
- Denmark
- Prior art keywords
- prostaglandin derivatives
- water
- liable
- ophthalmic solutions
- eye drops
- Prior art date
Links
- 239000003889 eye drop Substances 0.000 title 1
- 229940012356 eye drops Drugs 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- 239000002997 ophthalmic solution Substances 0.000 abstract 2
- SPSPIUSUWPLVKD-UHFFFAOYSA-N 2,3-dibutyl-6-methylphenol Chemical compound CCCCC1=CC=C(C)C(O)=C1CCCC SPSPIUSUWPLVKD-UHFFFAOYSA-N 0.000 abstract 1
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 abstract 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 abstract 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 235000010354 butylated hydroxytoluene Nutrition 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 abstract 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- -1 polyoxyethylene Polymers 0.000 abstract 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 abstract 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 abstract 1
- 229920000053 polysorbate 80 Polymers 0.000 abstract 1
- 229940068968 polysorbate 80 Drugs 0.000 abstract 1
- 125000003259 prostaglandin group Chemical class 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000277554 | 2000-09-13 | ||
| PCT/JP2001/007928 WO2002022131A1 (fr) | 2000-09-13 | 2001-09-13 | Collyre |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1321144T3 true DK1321144T3 (da) | 2011-03-07 |
Family
ID=18762864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01965597.6T DK1321144T3 (da) | 2000-09-13 | 2001-09-13 | Øjendråber |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20040097592A1 (da) |
| EP (1) | EP1321144B1 (da) |
| KR (1) | KR100854056B1 (da) |
| CN (1) | CN1243548C (da) |
| AT (1) | ATE490761T1 (da) |
| AU (1) | AU2001286210A1 (da) |
| CA (1) | CA2422031C (da) |
| CY (2) | CY1113200T1 (da) |
| DE (1) | DE60143615D1 (da) |
| DK (1) | DK1321144T3 (da) |
| ES (1) | ES2357551T3 (da) |
| NO (1) | NO332650B1 (da) |
| PT (1) | PT1321144E (da) |
| WO (1) | WO2002022131A1 (da) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2422031C (en) * | 2000-09-13 | 2011-11-15 | Santen Pharmaceutical Co., Ltd. | Ophthalmic solutions comprising difluoroprostaglandin f2 alpha |
| DK1532981T3 (da) * | 2002-08-23 | 2008-01-28 | Santen Pharmaceutical Co Ltd | Stabile öjendråber, der indeholder latanoprost som den aktive bestanddel |
| US7074827B2 (en) * | 2002-10-24 | 2006-07-11 | Sucampo Ag (Usa) Inc. | Method for treating ocular hypertension and glaucoma |
| WO2005011704A1 (ja) * | 2003-07-31 | 2005-02-10 | Santen Pharmaceutical Co., Ltd. | プロスタグランジン含有製品 |
| DE602004023106D1 (de) * | 2003-11-07 | 2009-10-22 | Senju Pharma Co | Pharmazeutische zusammensetzung mit prostaglandin |
| CN102526064A (zh) * | 2004-12-09 | 2012-07-04 | 参天制药株式会社 | 含有分子内具有氟原子的前列腺素的制品 |
| WO2006068266A1 (ja) * | 2004-12-24 | 2006-06-29 | Santen Pharmaceutical Co., Ltd. | プロスタグランジンF2a誘導体含有製品 |
| GB0501192D0 (en) | 2005-01-20 | 2005-03-02 | Resolution Chemicals Ltd | Stable prostaglandin-containing compositions |
| WO2006106915A1 (ja) | 2005-03-31 | 2006-10-12 | Asahi Glass Company, Limited | プロスタグランジンF2α誘導体を有効成分として含む網膜神経細胞保護剤 |
| JPWO2006112313A1 (ja) | 2005-04-13 | 2008-12-11 | 宇部興産株式会社 | インダゾール誘導体を有効成分として含む網膜神経細胞保護剤 |
| CN101400354B (zh) | 2006-03-13 | 2014-10-22 | 株式会社·R-技术上野 | 水性组合物 |
| FR2912207B1 (fr) * | 2007-02-01 | 2012-10-26 | Air Liquide | Procede et appareil de production de monoxyde de carbone par distillation cryogenique |
| WO2008123396A1 (ja) * | 2007-03-29 | 2008-10-16 | Santen Pharmaceutical Co., Ltd. | フルオロメトロンを含有する懸濁型点眼剤 |
| EP1985298A1 (en) * | 2007-04-24 | 2008-10-29 | Azad Pharma AG | Ophtalmic oil-in-water emulsions containing prostaglandins |
| TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
| WO2009131164A1 (ja) | 2008-04-23 | 2009-10-29 | 大塚製薬株式会社 | 点眼剤及び使用方法 |
| EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
| US20110136898A1 (en) * | 2008-08-05 | 2011-06-09 | University College Cork, National University Of Ireland, Cork | Treatment of retinal degeneration |
| CA2749352A1 (en) * | 2009-02-20 | 2010-09-10 | Micro Labs Limited | Storage stable prostaglandin product |
| EP2269575A1 (en) | 2009-06-30 | 2011-01-05 | Santen Pharmaceutical Co., Ltd | Method for improving bioavailability of latanoprost |
| US20110136872A1 (en) * | 2009-12-09 | 2011-06-09 | Burk Robert M | Stable aqueous compositions of prostglandin agonist prodrugs and methods for use thereof |
| ES2391721T3 (es) * | 2010-03-01 | 2012-11-29 | Laboratorios Salvat, S.A. | Disoluciones acuosas transparentes de acetónido de fluocinolona para el tratamiento de la infamación de oído |
| EP2452669A1 (en) | 2010-10-29 | 2012-05-16 | Omnivision GmbH | Ophthalmic composition |
| EP2567689A1 (en) | 2011-09-12 | 2013-03-13 | Visiotact Pharma | Ophthtalmic compositions comprising prostaglandin F2 alpha derivatives and hyaluronic acid |
| WO2013183778A1 (ja) * | 2012-06-08 | 2013-12-12 | ライオン株式会社 | 粘膜用組成物 |
| CN104288092A (zh) * | 2013-07-16 | 2015-01-21 | 广东东阳光药业有限公司 | 拉坦前列素滴眼剂 |
| CN104622798B (zh) * | 2014-12-05 | 2017-12-22 | 广东东阳光药业有限公司 | 一种含有他氟前列素的滴眼液及其制备方法 |
| WO2018033854A1 (en) | 2016-08-15 | 2018-02-22 | Santen Pharmaceutical Co., Ltd. | Ophthalmic composition and a method for treating ocular hypertension and glaucoma |
| EP3590513A4 (en) * | 2017-02-28 | 2020-12-30 | Kowa Company, Ltd. | DRUG |
| ES2972844T3 (es) * | 2017-03-27 | 2024-06-17 | Alcon Inc | Preparación farmacéutica |
| EA202190214A1 (ru) | 2018-07-09 | 2021-04-16 | Варшавске Закляды Фармацеутычне Польфа Са | Офтальмологическое дозирующее устройство |
| CA3112278A1 (en) * | 2018-09-21 | 2020-03-26 | Ps Therapy Ltd. | Artificial tear, contact lens and drug vehicle compositions and methods of use thereof |
| WO2020085812A1 (ko) | 2018-10-25 | 2020-04-30 | 주식회사 넥스모스 | 압타민c를 유효성분으로 포함하는 점안액 조성물 |
| CN115397392A (zh) * | 2019-12-05 | 2022-11-25 | Vanda制药公司 | 眼用药物组合物 |
| US12357594B1 (en) | 2021-06-30 | 2025-07-15 | Sage Products, Llc | Antimicrobial solution for pre-operative preparation |
| CN117180188B (zh) * | 2023-08-24 | 2026-04-24 | 南京海纳制药有限公司 | 一种含有他氟前列素滴眼水性药物及其制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4310543A (en) * | 1980-10-09 | 1982-01-12 | Hoffmann-La Roche Inc. | Prostaglandin compositions |
| DE3850676T2 (de) * | 1987-09-18 | 1994-11-03 | Ueno Seiyaku Oyo Kenkyujo Kk | Hypotensive okulare Mittel. |
| JPH0662417B2 (ja) * | 1987-12-25 | 1994-08-17 | 参天製薬株式会社 | 抗アレルギー点眼液 |
| US5565492A (en) * | 1988-07-18 | 1996-10-15 | Alcon Laboratories, Inc. | Prostaglandin combinations in glaucoma therapy |
| JPH063800A (ja) * | 1992-06-16 | 1994-01-14 | Dainippon Screen Mfg Co Ltd | 画像処理方法 |
| AU665287B2 (en) * | 1992-12-21 | 1995-12-21 | Alcon Laboratories, Inc. | Prostaglandin combinations in glaucoma therapy |
| US5486540A (en) * | 1993-10-28 | 1996-01-23 | Allergan, Inc. | Cyclopentane heptanoic or heptenoic acid, 2-arylalkyl or arylalkenyl and derivatives as therapeutic agents |
| US5631287A (en) * | 1994-12-22 | 1997-05-20 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
| ATE221048T1 (de) * | 1996-09-17 | 2002-08-15 | Asahi Glass Co Ltd | Fluorierte prostaglandinderivate und medikamente |
| JP3480549B2 (ja) * | 1996-12-26 | 2003-12-22 | 参天製薬株式会社 | ジフルオロプロスタグランジン誘導体およびその用途 |
| AR002194A1 (es) * | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
| WO2000003736A1 (en) * | 1998-07-14 | 2000-01-27 | Alcon Laboratories, Inc. | Prostaglandin product |
| US6235781B1 (en) * | 1998-07-14 | 2001-05-22 | Alcon Laboratories, Inc. | Prostaglandin product |
| AU2183900A (en) * | 1998-12-24 | 2000-07-31 | Alcon Laboratories, Inc. | Ep4 receptor agonists for treatment of dry eye |
| AU778270C (en) * | 1999-01-19 | 2005-07-21 | Pharmacia & Upjohn Company | Gamma-irradiation sterilized polyethylene packaging |
| CA2422031C (en) * | 2000-09-13 | 2011-11-15 | Santen Pharmaceutical Co., Ltd. | Ophthalmic solutions comprising difluoroprostaglandin f2 alpha |
| TW586946B (en) * | 2000-12-22 | 2004-05-11 | Novartis Ag | Process to improve stability |
| WO2005011704A1 (ja) * | 2003-07-31 | 2005-02-10 | Santen Pharmaceutical Co., Ltd. | プロスタグランジン含有製品 |
| US20050049311A1 (en) * | 2003-09-03 | 2005-03-03 | Pharmacia & Upjohn Company | Medicinal products comprising prostaglandin compositions and methods of packaging such compositions |
-
2001
- 2001-09-13 CA CA2422031A patent/CA2422031C/en not_active Expired - Lifetime
- 2001-09-13 EP EP01965597A patent/EP1321144B1/en not_active Expired - Lifetime
- 2001-09-13 PT PT01965597T patent/PT1321144E/pt unknown
- 2001-09-13 CN CNB018156177A patent/CN1243548C/zh not_active Ceased
- 2001-09-13 KR KR1020037003605A patent/KR100854056B1/ko not_active Ceased
- 2001-09-13 ES ES01965597T patent/ES2357551T3/es not_active Expired - Lifetime
- 2001-09-13 WO PCT/JP2001/007928 patent/WO2002022131A1/ja not_active Ceased
- 2001-09-13 US US10/380,401 patent/US20040097592A1/en not_active Abandoned
- 2001-09-13 DE DE60143615T patent/DE60143615D1/de not_active Expired - Lifetime
- 2001-09-13 DK DK01965597.6T patent/DK1321144T3/da active
- 2001-09-13 AT AT01965597T patent/ATE490761T1/de active
- 2001-09-13 AU AU2001286210A patent/AU2001286210A1/en not_active Abandoned
-
2003
- 2003-03-12 NO NO20031138A patent/NO332650B1/no not_active IP Right Cessation
-
2007
- 2007-06-26 US US11/823,068 patent/US20070248697A1/en not_active Abandoned
-
2011
- 2011-02-28 CY CY20111100235T patent/CY1113200T1/el unknown
- 2011-07-28 CY CY2011007C patent/CY2011007I2/el unknown
-
2015
- 2015-12-28 US US14/980,685 patent/US20160106757A1/en not_active Abandoned
-
2018
- 2018-08-21 US US16/106,634 patent/US20180353518A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20180353518A1 (en) | 2018-12-13 |
| DE60143615D1 (de) | 2011-01-20 |
| CN1457256A (zh) | 2003-11-19 |
| PT1321144E (pt) | 2011-03-10 |
| NO20031138L (no) | 2003-05-12 |
| CA2422031A1 (en) | 2003-03-12 |
| CA2422031C (en) | 2011-11-15 |
| ES2357551T3 (es) | 2011-04-27 |
| CN1243548C (zh) | 2006-03-01 |
| US20160106757A1 (en) | 2016-04-21 |
| NO332650B1 (no) | 2012-11-26 |
| ATE490761T1 (de) | 2010-12-15 |
| CY1113200T1 (el) | 2014-04-09 |
| EP1321144A4 (en) | 2009-07-29 |
| CY2011007I1 (el) | 2014-04-09 |
| WO2002022131A1 (fr) | 2002-03-21 |
| AU2001286210A1 (en) | 2002-03-26 |
| CY2011007I2 (el) | 2015-08-05 |
| KR100854056B1 (ko) | 2008-08-26 |
| US20040097592A1 (en) | 2004-05-20 |
| KR20030029981A (ko) | 2003-04-16 |
| EP1321144A1 (en) | 2003-06-25 |
| US20070248697A1 (en) | 2007-10-25 |
| EP1321144B1 (en) | 2010-12-08 |
| NO20031138D0 (no) | 2003-03-12 |
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